• KSII Transactions on Internet and Information Systems (TIIS)
• /
• v.12 no.11
• /
• pp.5344-5356
• /
• 2018

Nowadays with the help of Location-Based Social Networks (LBSNs), users of Point-of-Interest (POI) recommendation service in LBSNs are able to publish their geo-tagged information and physical locations in the form of sign-ups and share their experiences with friends on POI, which can help users to explore new areas and discover new points-of-interest, and promote advertisers to push mobile ads to target users. POI recommendation service in LBSNs is attracting more and more attention from all over the world. Due to the sparsity of users' activity history data set and the aggregation characteristics of sign-in area, conventional recommendation algorithms usually suffer from low accuracy. To address this problem, this paper proposes a new recommendation algorithm based on a novel Preference-Content-Region Model (PCRM). In this new algorithm, three kinds of information, that is, user's preferences, content of the Point-of-Interest and region of the user's activity are considered, helping users obtain ideal recommendation service everywhere. We demonstrate that our algorithm is more effective than existing algorithms through extensive experiments based on an open Eventbrite data set.

• Journal of Animal Reproduction and Biotechnology
• /
• v.37 no.3
• /
• pp.176-182
• /
• 2022

Norflurazon is widely used on agricultural lands and has a high potential to pollute water sources. However, its effects on fish have not been fully elucidated. The purpose of our study was to determine whether norflurazon adversely affects the developmental stage of zebrafish, which are frequently used as a model system to evaluate the environmental impact of pollutants. Norflurazon interfered with the hatching of zebrafish embryos and induced several sublethal deformities including body length reduction, increased yolk sac volume, and enlargement of the pericardial region. We further examined the cardiotoxicity of norflurazon in the flk1:eGFP transgenic zebrafish line. The vascular network, mainly in the brain region, was significantly disrupted in norflurazon-exposed zebrafish. In addition, due to the failure of cardiac looping, norflurazon-exposed zebrafish had an abnormal cardiac structure. These developmental abnormalities were related to the apoptotic process triggered by norflurazon. Overall, the present study demonstrated the non-target toxicity of norflurazon by analyzing the hazardous effects of norflurazon on developing zebrafish.

• Journal of Nuclear Fuel Cycle and Waste Technology(JNFCWT)
• /
• v.21 no.1
• /
• pp.165-173
• /
• 2023

Various linear system solvers with multi-physics analysis schemes are compared focusing on the near-field region considering thermal-hydraulic-chemical (THC) coupled multi-physics phenomena. APro, developed at KAERI for total system performance assessment (TSPA), performs a finite element analysis with COMSOL, for which the various combinations of linear system solvers and multi-physics analysis schemes should to be compared. The KBS-3 type disposal system proposed by Sweden is set as the target system and the near-field region, which accounts for most of the computational burden is considered. For comparison of numerical analysis methods, the computing time and memory requirement are the main concerns and thus the simulation time is set up to one year. With a single deposition hole problem, PARDISO and GMRES-SSOR are selected as representative direct and iterative solvers respectively. The performance of representative linear system solvers is then examined through a problem with an increasing number of deposition holes and the GMRES-SSOR solver with a segregated scheme shows the best performance with respect to the computing time and memory requirement. The results of the comparative analysis are expected to provide a good guideline to choose better numerical analysis methods for TSPA.

• SUVANNABHUMI
• /
• v.11 no.2
• /
• pp.59-83
• /
• 2019

The Chinese Belt Road initiatives in the Southeast Asian countries marked a new chapter in the development of China political influence on this region. This article looks at the initiative from the cultural dimension and aims to place its narrative as the entry point to understand the use of identity politics in Asian countries that target the Chinese diaspora. This topic relates to the primordial sentiments of Southeast Asian nations amid massive Chinese investment in the region. The issue of Chinese investments under the Belt Road Initiative corridor has a relationship with the formation of anti-Chinese discourse and anti-communist in some Southeast Asian countries. We took the cases of Indonesian and Malaysian elections to observe the use of identity politics and anti-Chinese political discourse in Southeast Asia. In both cases, a common issue emerged, that of the strengthening both Islamic and indigenous sensibilities. The establishment of ASEAN during the Cold War may be seen then as an anti-thesis to emerging Chinese power. However, anti-Chinese and anti-communism sentiments were not enough to unite the forces of the nations of Southeast Asia. We have concluded that brotherhood, mutual prosperity, and anti-neo-colonialism are yet to be fostered completely to make a distinct ASEAN identity.

• Journal of the Korean Society of Surveying, Geodesy, Photogrammetry and Cartography
• /
• v.28 no.6
• /
• pp.579-586
• /
• 2010

Due to the recent development of measuring technology and 3D programs, it has become possible to obtain various spatial data. This study utilizes the 2-dimensional data and 3-dimensional data extraction technology based on the existing empirical and statistical DB. The data obtained from geospatial data technology are integrated with civil engineering BIM to conduct the modeling of the topography of the target region and select the optimum location condition by using the cut and fill balance of the volume of earth. The target area is the land around Tamjin River, Jangheong-gun, Jeolla-do. The 3-dimensional topology linked with 3-dimensional mapping technology by using the orth-image and aerial LiDAR that uses aerial photo of the target area is visualized with Civil3D of AutoDesk. By using Civil3D program, the Thanks to the recent development of measuring technology and 3D programs, target area is analyzed through visualization and related data can be obtained for analysis. The method of using civil engineering BIM enables to obtain various and accurate information about the target area which is helpful for addressing the issues risen from the existing methodology. In this regard, it aims at searching for the alternatives and provides suggestions to utilize the information.

• Radiation Oncology Journal
• /
• v.11 no.2
• /
• pp.431-437
• /
• 1993

An important problem in radiosurgery is the utilization of the proper beam parameters, to which dose shape is sensitive. Streotactic radiosurgery techniques for a linear accelerator typically, use circular radiation fields with multiple arcs to produce an spherical radiation distribution. Target volumes are irregular in shape for a certain case, and spherical distributions can irradiate normal tissues to high dose as well as the target region. The current improvement to dose distribution utilizes treating multiple isocenters or weighting various arcs to change treatment volume shape. in this paper another promising study relies upon dynamically shaping the treatment beam to fit the beam's eye view of the target. This conformal irradiation technique was evaluated by means of visual three dimensional dose distribution, dose volume histograms to the target volume and surrounding normal brain. It is shown that using even less arcs than multiple isocenter irradiation technique, the conformal therapy yields comparable dose gradients and superior homogeneity of dose within the target volume.

• Journal of Life Science
• /
• v.27 no.7
• /
• pp.767-782
• /
• 2017

MicroRNAs control the differentiation and proliferation of human adipose tissue-derived stromal cells (hADSCs). However, the role of miR-200a and miR210 on the osteogenic differentiaton of hADSCs has not been determined. hADSCs were isolated from human adipose tissues. Direct binding of mircoRNA to target mRNAs was determined by luciferase assay of the constructs containing putative microRNA binding sites within 3' untranslated region of target mRNAs. Overexpression of miR-200a increased the proliferation and osteogenic differentiation of hADSCs, while causing downregulation of the levels of ZEB2. Inhibition of miR-200a with antisense RNAs inhibited the proliferation and osteogenic differentiation of hADSCs. Overexpression of miR-210 was found to inhibit the proliferation of hADSCs but increase the osteogenic differentiation, while causing downregulation of the levels of IGFBP3. Inhibition of miR-210 with antisense RNAs increased the proliferation but inhibited the osteogenic differentiation of hADSCs. Analysis of the luciferase activity of the constructs containing the miR-200a target site within the ZEB2 3' region and the miR-210 target site within the IGFBP3 3' region revealed lower activity in the miR-200a- or miR-210-transfected hADSCs than in control miRNA-transfected hADSCs. Downregulation of ZEB2 or IGFBP3 in the hADSCs showed similar effects on both their proliferation and osteogenic differentiation with that of miR-200a and miR-210 overexpression, respectively. The results of the current study indicate that miR-200a and miR-210 regulate the osteogenic differentiation and proliferation of hADSCs through the direct targeting of IGFBP3 and ZEB2, respectively.

• Journal of the Korean Ceramic Society
• /
• v.39 no.10
• /
• pp.935-942
• /
• 2002

Gallium-doped ZnO (GZO) films were deposited on soda-lime glass substrate without heating using Ne, Ar, or Kr gas. Electrical properties of GZO films deposited at various total gas pressures were investigated for the film positions corresponding to the erosion region (region B) and outside the erosion region (region A) of the target. Region B showed high resistivity, which was attributed to the decrease in carrier density and Hall mobility, compared to region A. GZO films deposited using Ne gas showed the degradation in resistivity and crystallinity, whereas, GZO films deposited using Kr gas showed the improvement in resistivity and crystallinity. This degradation in film properties could be attributed to the film damage caused by the bombardment of high-energy particles. Especially, the energies of recoiled neutral atoms ($Ne^0,\;Ar^0,\;Kr^0$) calculated by Monte Carlo simulation corresponded to experimental results.

• The Journal of Korean Institute of Communications and Information Sciences
• /
• v.41 no.4
• /
• pp.387-394
• /
• 2016

A stereo matching method is one of the ways to obtain a depth value from two dimensional images. This method estimates the depth value of target images using stereo images which have two different viewpoints. In the result of stereo matching, the depth value is represented by a disparity value. The disparity means a distance difference between a current pixel in one side of stereo images and its corresponding point in the other side of stereo images. The stereo matching in a homogeneous region is always difficult to find corresponding points because there are no textures in that region. In this paper, we propose a novel matching equation using the distance transform to estimate accurate disparity values in the homogeneous region. The distance transform calculates pixel distances from the edge region. For this reason, pixels in the homogeneous region have specific values when we apply this transform to pixels in that region. Therefore, the stereo matching method using the distance transform improves the matching accuracy in the homogeneous regions. In addition, we also propose an adaptive matching cost computation using a kernel of one dimensional array depending on the characteristic of regions in the image. In order to aggregate the matching cost, we apply a cross-scale cost aggregation method to our proposed method. As a result, the proposed method has a lower average error rate than that of the conventional method in all regions.

• Reproductive and Developmental Biology
• /
• v.32 no.1
• /
• pp.33-38
• /
• 2008

DNA methylation is involved in tissue-specific gene control and essential for normal embryo development Octamer-binding transcription factor 4 (Oct-4) is one of the most important transcription factors for early differentiation. This study was performed whether the bovine Oct-4 is tissue specific or developmental dependent epigenetic mark, we investigated transcripts and the methylation status of CpGs of 5'-promoter region of Oct-4 in bovine preimplantation embryos. Oct-4 transcripts were highly detected in morula and blastocyst, while they were present low levels in sperm and 2- to 8-cell stage embryos. These results suggest that de novo expression of Oct-4 initiates at morula stage of embryogenesis. Here we determined that there is a tissue-dependent differentially methylated region (T-DMR) in the 5'-promoter region of Oct-4. The methylation status of the Oct-4 T-DMR was distinctively different in the oocyte from that in the sperm and adult somatic tissues and changed from zygote to blastocyst stage, suggesting that active methylation and demethylation occur during preimplantation development. Based on these results, the 5'-promoter region of Oct-4 gene is target for DNA methylation and the methylation status changes variously during embryonic development in bovine.