• 제목/요약/키워드: Target Synthesis

검색결과 462건 처리시간 0.03초

CDM과 리파토프 정리를 이용한 구간 플랜트의 목적다항식 설계 (Target Polynomial Design for Interval Plant Using Lipatov Theorem and CDM)

  • 오학준;정태진;이진규;정찬수
    • 대한전기학회논문지:시스템및제어부문D
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    • 제50권1호
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    • pp.1-7
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    • 2001
  • For a parametric uncertain system, there are many results on stability analysis, but only a few synthesis methods. In this paper, we proposed a new target polynomial decision method for the parametric uncertain system to stabilize the closed loop system with maximal parametric $l_2$ stability margin. To this, we used both Lipatov Theorem and coefficient diagram method(CDM). To show the effectiveness of the proposed method, we designed a robust controller for the inverted pendulum system with parametric uncertainties using fixed order pole assignment(FOPA) method and its performance was compared with that of the ${\mu}$ synthesis methods.

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Regulation of skeletal muscle protein synthesis by amino acid and resistance exercise

  • Nakai, Naoya
    • 운동영양학회지
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    • 제15권4호
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    • pp.153-161
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    • 2011
  • The maintenance of skeletal muscle mass is very important for the prevention of life style-related diseases and the improvement of quality of life. It is well-known that resistance exercise and nutrition (especially amino acids) are the most effective interventions for maintaining skeletal muscle mass. It has been reported that many molecules are involved in the regulation of protein synthesis in response to resistance exercise and nutrition. Understanding the molecular mechanisms regulating muscle protein synthesis is crucial for the development of appropriate interventions. The role of intracellular signaling pathways through the mammalian target of rapamycin (mTOR), a serine/threonine protein kinase in the regulation of muscle protein synthesis, has been extensively investigated for these years. Control of protein synthesis by mTOR is mediated through phosphorylation of downstream targets that modulate translation initiation and elongation step. In contrast, upstream mediators regulating mTOR and protein synthesis in response to resistance exercise and amino acid still needed to be determined. In this brief review, we discuss the current progress of intracellular mechanisms for exercise- and amino acid-induced activation of mTOR pathways and protein synthesis in skeletal muscle.

이동하는 표적의 방사소음 합성기법 연구 (Research on Synthesis of Radiation Noise from Moving Target)

  • 배재휘
    • 한국군사과학기술학회지
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    • 제3권1호
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    • pp.58-65
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    • 2000
  • A target signal simulation method for passive sonar systems is introduced. The method uses multirate signal processing techniques to simulate moving target signals in the multi-path sound propagation environment by introducing Lloyd's mirror and Doppler effect. Time and frequency variation of target signal due to the target maneuvering is also considered to provide realistic ship signatures in the LOFAR gram so that the simulated target is used for sonar operator training. Synthesized target characteristics is analyzed and compared with real target signal in terms of interference pattern and frequency variation in the LOFAR gram.

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부울함수의 XOR 표현을 기초로 한 저전력 논리합성 (Low Power Logic Synthesis based on XOR Representation of Boolean Functions)

  • 황민;이귀상
    • 대한전자공학회:학술대회논문집
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    • 대한전자공학회 2000년도 추계종합학술대회 논문집(2)
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    • pp.337-340
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    • 2000
  • In this paper, we put forth a procedure that target low power logic synthesis based on XOR representation of Boolean functions, and the results of synthesis procedure are a multi-level XOR form with minimum switching activity. Specialty, this paper show a method to extract the common cubes or kernels by Boolean matrix and rectangle covering, and to estimate the power consumption in terms of the extracted common sub-functions.

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A Possible Target for the Heat Inactivation of SCK Tumor Cells

  • 강만식;정주영
    • 한국동물학회지
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    • 제32권4호
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    • pp.305-313
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    • 1989
  • The present investigation aims at inquiring into a possible target for the heat inactivation of SCK tumor cells by comparing the kinetics of cell survival, rate of protein synthesis, and DNA polymerase activity in the presence of heat protector or heat sensitirer. A possible conclusion to be drawn from the present experiment is that there is no direct correlation between cell death and decrease in the rate of protein synthesis, but that the loss of DNA polvmerase $\beta$ activity correlates quite well with cell inactivation. Thus, protein degrada-tion and/or abnormal protein synthesis causes cell inactivation innireuv, possibly by altering the cellular environment which in turn affects the DNA polymerase $\beta$ activity. Accordingly, further studies, dealing with the correlation between changes in the cellular environment and DNA polymerase $\beta$ activity, are needed to set insight into a possible target for the heat inactivation of cells. 본 연구는 열보호제 또는 열증감제의 존재하에서 세포 생존곡선, 단백질 합성률, DNA 중합효소 $\beta$의 활성변화를 비교 검토함으로써 SCK 종양세포가 열에 의해서 불활성화될 때의 표적이 무엇인지를 밝혀보기 위해서 수행되었다. 본 실험의 결과로 추정하건대 열에 의한 세포치사는 단백질 합성률의 변화와는 직접적인 연관성이 없으나, DNA 중합효소 $\beta$의 활성도와는 밀접한 연관성이 있음을 알 수 있다. 즉, 단백질의 분해 또는 비정상적인 단백질의 합성이 세포의 환경을 변화시키고 이것이 DNA 중합효소 $\beta$의 활성에 영향을 미침으로써 간접적으로 세포의 치사를 초래할 것으로 짐작할 수 있다. 따라서, 세포의 열불화성화의 표적을 좀더 분명히 밝히기 위해서는 세포의 환경변화와 DNA 중합효소 $\beta$의 활성과의 관계를 추구하는 연구가 수행되어야 할 것으로 사료된다.

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선배열 예인음탐기 표적신호 시뮬레이터 개발 (Development of Target Signal Simulator for Towed Line Array Sonar)

  • 손권;최재용
    • 한국군사과학기술학회지
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    • 제6권3호
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    • pp.36-43
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    • 2003
  • Multi-target away signal simulator which can simulate the radiated noises of maneuvering targets in a specified ocean range is an essential equipment for the validation of developed towed array sonar system. This simulator should provide realistic multi-channel signals those are required for beamforming on the signal processing unit of towed away system. This paper describes the overall system configuration and signal synthesis techniques for the target radiated noise. And this paper considers why the time delays between target and individual sensors are caused and how to compensate these time delays to individual sensors output. This multi-purpose target simulator could be used for the training of TASS operators.

능동소나 표적 인식을 위한 신호합성 및 특징추출 (Signal Synthesis and Feature Extraction for Active Sonar Target Classification)

  • 어윤;석종원
    • 한국멀티미디어학회논문지
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    • 제18권1호
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    • pp.9-16
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    • 2015
  • Various approaches to process active sonar signals are under study, but there are many problems to be considered. The sonar signals are distorted by the underwater environment, and the spatio-temporal and spectral characteristics of active sonar signals change in accordance with the aspect of the target even though they come from the same one. And it has difficulties in collecting actual underwater data. In this paper, we synthesized active target echoes based on ray tracing algorithm using target model having 3-dimensional highlight distribution. Then, Fractional Fourier transform was applied to synthesized target echoes to extract feature vector. Recognition experiment was performed using probabilistic neural network classifier.

Guidance Synthesis to Control Impact Angle and Time

  • Shin, Hyo-Sang;Lee, Jin-Ik;Tahk, Min-Jea
    • International Journal of Aeronautical and Space Sciences
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    • 제7권1호
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    • pp.129-136
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    • 2006
  • A new guidance synthesis for anti-ship missiles to control impact angle and impact time is proposed in this paper. The flight vehicle is assumed as a 1st order lag system to consider more practical system. The proposed guidance synthesis enhances the survivability of anti-ship missiles because multiple anti-ship missiles with the proposed synthesis can hit the target simultaneously. The control input to satisfy constraints of zero miss distance and impact angle, and the feedforward bias control input to control impact time constitute the guidance law. The former is from trajectory shaping guidance, the latter is from neural network. And particle swarm optimization method is introduced to furnish reference input and output for learning in neural network. The performance of the proposed synthesis in the accuracy of impact time and angle is validated by numerical examples.

Nano-particles of Mechanochemical Synthesis

  • Urakaev, Farit Kh.
    • 동굴
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    • 제71호
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    • pp.5-11
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    • 2006
  • A theoretical investigation of the solid phase mechanochemical synthesis of nano sized target product on the basis of dilution of the initial powdered reagent mixture by another product of an exchange reaction is presented. On the basis of the proposed 3 mode particle size distribution in mechanically activated mixture, optimal molar ratios of the components in mixture are calculated, providing the occurrence of impact friction contacts of reagent particles and excluding aggregation of the nanosized particles of the target reaction product. Derivation of kinetic equations for mechanochemical synthesis of nanoscale particles by the final product dilution method in the systems of exchange reactions is submitted. On the basis of obtained equations the necessary times of mechanical activation for complete course of mechanochemical reactions are designed. Kinetics of solid phase mechanosynthesis of nano TlCl by dilution of initial (2NaCl+$Tl_2SO_4$) mixture with the exchange reaction product (diluent,$zNa_2SO_4$, z=z*=11.25) was studied experimentally. Some peculiar features of the reaction mechanism were found. Parameters of the kinetic curve of nano TlCl obtained experimentally were compared with those for the model reaction KBr+TlCl+zKCl=(z+1) KCl+TlBr (z=z1*=13.5), and for the first time the value of mass transfer coefficient in a mechanochemical reactor with mobile milling balls was evaluated. Dynamics of the size change was followed for nanoparticle reaction product as a function of mechanical activation time.

Rapamycin Inhibits Expression of Elongation of Very-long-chain Fatty Acids 1 and Synthesis of Docosahexaenoic Acid in Bovine Mammary Epithelial Cells

  • Guo, Zhixin;Wang, Yanfeng;Feng, Xue;Bao, Chaogetu;He, Qiburi;Bao, Lili;Hao, Huifang;Wang, Zhigang
    • Asian-Australasian Journal of Animal Sciences
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    • 제29권11호
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    • pp.1646-1652
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    • 2016
  • Mammalian target of rapamycin complex 1 (mTORC1) is a central regulator of cell growth and metabolism and is sufficient to induce specific metabolic processes, including de novo lipid biosynthesis. Elongation of very-long-chain fatty acids 1 (ELOVL1) is a ubiquitously expressed gene and the product of which was thought to be associated with elongation of carbon (C) chain in fatty acids. In the present study, we examined the effects of rapamycin, a specific inhibitor of mTORC1, on ELOVL1 expression and docosahexaenoic acid (DHA, C22:6 n-3) synthesis in bovine mammary epithelial cells (BMECs). We found that rapamycin decreased the relative abundance of ELOVL1 mRNA, ELOVL1 expression and the level of DHA in a time-dependent manner. These data indicate that ELOVL1 expression and DHA synthesis are regulated by mTORC1 in BMECs.