• Title/Summary/Keyword: Tae-Eum type

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Energy metabolism and whole-exome sequencing-based analysis of Sasang constitution: a pilot study

  • Kim, Hyoung Kyu;Lee, Heetak;So, Ji Ho;Jeong, Seung Hun;Seo, Dae Yun;Kim, Jong-Yeol;Kim, Sanguk;Han, Jin
    • Integrative Medicine Research
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    • v.6 no.2
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    • pp.165-178
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    • 2017
  • Background: Traditional Korean Sasang constitutional (SC) medicine categorizes individuals into four constitutional types [Tae-eum (TE), So-eum (SE), Tae-yang (TY), or So-yang (SY)] based on biological and physiological characteristics. As these characteristics are closely related to the bioenergetics of the human body, we assessed the correlation between SC type and energy metabolism features. Methods: Forty healthy, young ($22.3{\pm}1.4$ years) males volunteered to participate in this study. Participants answered an SC questionnaire, and their face shape, voice tone, and body shape were assessed using an SC analysis tool. Thirty-one participants (10 TE, 10 SE, 3 TY, and 8 SY) were selected for further analysis. Collected blood samples were subjected to blood composition analysis, mitochondrial function analysis, and whole-exome sequencing. Results: The SY type showed significantly lower total cholesterol and high-density lipoprotein cholesterol levels than the SE type. Cellular and mitochondrial Adenosine triphosphate (ATP) levels were similar across types. All types showed similar basal mitochondrial oxygen consumption rates, whereas the TE type showed a significantly lower ATP-linked oxygen consumption rate than the other types. Whole-exome sequencing identified several genes variants that were exclusively detected in particular SC types, including 19 for SE, seven for SY, 11 for TE, and six for TY. Conclusion: SC type-specific differences in mitochondrial function and gene mutations were detected in a small group of healthy, young Korean males. These results are expected to greatly improve the accurate screening and utilization of SC medicine.

Cross-sectional study on the distribution of Sasang constitution in acute stroke patients (급성기 뇌경색 환자의 사상체질별 분포에 관한 단면적 연구)

  • Sun, Jong-joo;Jung, Jae-han;Jung, Woo-sang;Moon, Sang-kwan;Cho, Ki-ho;Ko, Seong-gyu;Chen, Chan-yong;Han, Chang-ho
    • The Journal of the Society of Stroke on Korean Medicine
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    • v.7 no.1
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    • pp.40-45
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    • 2006
  • Objectives : This study was aimed to assess the distribution of Sasang constitution(SC) in acute stroke patients. Methods : We assessed the type of SC of acute stroke patients in the oriental medical hospitals of 3 universities located in metropolitan region from October 2005 to October 2006 by Questionnaire for the Sasang Constitution Clssification II(QSCCII). We investigated general characteristics, stroke type, blood test results, alcohol drinking, smoking and dietary preferences according to SC. Results : 236 subjects were included into the final analysis. 1. This study showed that the proportion of So-yang was highest of all constitutions(45.3%). And the body weight, body mass index, the waist circumference(WC), the hip circumference(HC), and the WC/HC ratio recorded the significantly high result in Tae-eum. 2. In the TOAST classification, SVO was the major type occupying 81.7% in the total subjects. 3. In Tae-eum, total cholesterol, triglyceride and 2 hours postprandial plasma glucose level were the highest and fasting glucose was significantly highest of all constitutions. Conclusion : From this study, we could roughly seize the distribution of Sasang constitution in acute stroke patients. For the further research, it seems to be necessary to construct fundamental databases for stroke by increasing the number of patients and by analyzing delicate characteristics of each constitution type.

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Study on the Psychobiological Characteristics of Sasang Typology Based on the Type-Specific Pathophysiological Digestive Symptom (사상 소화기능 소증에 따른 체질별 생리심리 특성 연구)

  • Chae, Han;Kim, Sung Hye;Han, Seung Yoon;Lee, Sang Jae;Kim, Byung Joo;Kwon, Young Kyu;Lee, Soo Jin
    • Journal of Physiology & Pathology in Korean Medicine
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    • v.28 no.4
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    • pp.417-424
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    • 2014
  • The purpose of this study was to analyze the psychobiological traits of each Sasang typology based on the Sasang Digestive function Inventory (SDFI) which measures the Sasang type-specific pathophysiological digestive symptom. The SDFI, Temperament and Character Inventory (TCI) and NEO-Personality Inventory (NEOPI) were measured with 199 College students. The correlation coefficient was measured with Pearson correlation among SDFI, TCI, and NEOPI. The influence of TCI, sex and age on SDFI and its subscales were analyzed with regression analysis. We also compared the psychobiological features between high and low SDFI score groups to elucidate its psychobiological profiles. There was significant correlation between SDFI and TCI Harm-Avoidance (r=-0.192, p<0.001). The SDFI subscales were showed to have significant correlations with subscales of NEOPI and TCI. The regression model with TCI can explain 8-16% of type-specific pathophysiological digestive symptoms. The low SDFI score group ($39{\pm}9.3$) has significantly (p=0.007) higher than the high SDFI group ($33.6{\pm}12.2$) in TCI Harm-Avoidance which is considered important for the gastrointestinal dysfunction and So-Eum type differentiation. We found that the TCI may explain the mechanism underneath the Sasang type-specific pathophysiological symptom. It was suggested that the TCI Reward-Dependence would be useful for the study on Tae-Eum Sasang type, and its clinical meanings were discussed in the pathophysiological perspectives.

Data mining Algorithms for the Development of Sasang Type Diagnosis (사상체질 진단검사를 위한 데이터마이닝 알고리즘 연구)

  • Hong, Jin-Woo;Kim, Young-In;Park, So-Jung;Kim, Byoung-Chul;Eom, Il-Kyu;Hwang, Min-Woo;Shin, Sang-Woo;Kim, Byung-Joo;Kwon, Young-Kyu;Chae, Han
    • Journal of Physiology & Pathology in Korean Medicine
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    • v.23 no.6
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    • pp.1234-1240
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    • 2009
  • This study was to compare the effectiveness and validity of various data-mining algorithm for Sasang type diagnostic test. We compared the sensitivity and specificity index of nine attribute selection and eleven class classification algorithms with 31 data-set characterizing Sasang typology and 10-fold validation methods installed in Waikato Environment Knowledge Analysis (WEKA). The highest classification validity score can be acquired as follows; 69.9 as Percentage Correctly Predicted index with Naive Bayes Classifier, 80 as sensitivity index with LWL/Tae-Eum type, 93.5 as specificity index with Naive Bayes Classifier/So-Eum type. The classification algorithm with highest PCP index of 69.62 after attribute selection was Naive Bayes Classifier. In this study we can find that the best-fit algorithm for traditional medicine is case sensitive and that characteristics of clinical circumstances, and data-mining algorithms and study purpose should be considered to get the highest validity even with the well defined data sets. It is also confirmed that we can't find one-fits-all algorithm and there should be many studies with trials and errors. This study will serve as a pivotal foundation for the development of medical instruments for Pattern Identification and Sasang type diagnosis on the basis of traditional Korean Medicine.

Study on the Revision and Clinical Validation of the Sasang Digestive Function Inventory (사상소화기능검사의 개정 및 임상 타당화 연구)

  • Lee, Yong-jae;Lee, Seul;Kim, So-hyung;Lee, Jeongyun;Chae, Han
    • Journal of Sasang Constitutional Medicine
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    • v.33 no.3
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    • pp.54-71
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    • 2021
  • Objectives The purpose of this study was to revise Sasang Digestive Function Inventory (SDFI) and improve its validity and reliability using clinical data. Methods The Sasang type and Cold-Heat pattern differentiation by certified clinical specialist and responses to SDFI items were acquired from 419 hospital patients. The revision of SDFI was performed using item analysis and Explorative Factor Analysis (EFA). Furthermore, the validity and reliability of the revised SDFI (rSDFI) were investigated using Confirmatory Factor Analysis (CFA), Internal Consistency and Item Response Theory (IRT). And, clinical significance of the rSDFI was examined for the differentiation of Sasang types and Cold-Heat patterns. Results The number of the SDFI items were modified from 21 to 15. And, the validity and reliability of the rSDFI subscale structure were found to be acceptable. The scores of rSDFI-total and rSDFI-E significantly decreased in the order of Tae-Eum (TE), So-Yang (SY), So-Eum (SE) types, and the rSDFI score of SE type was significantly lower than that of TE and SY types. The rSDFI-total score could differentiate Cold-Heat pattern in both SY and SE types. And the difference of digestive function between Cold and Heat pattern of SE type could be explained with the rSDFI-D score. The rSDFI-total score in Cold pattern significantly decreased in the order of TE, SY, and SE types, and the rSDFI-total score of TE type is significantly higher than that of SE type in Heat pattern. Conclusions Current results demonstrated the reliability, validity and clinical usefulness of the rSDFI in clinical patients. Therefore, rSDFI can be utilized as an objective clinical measure supporting the differential diagnosis of Sasang typology.

Effect of Safety Factors of Public Transportation on Customer Satisfaction (대중교통의 안전요인이 고객만족에 미치는 영향)

  • Woo, Tae-Hee;Eum, Kee-Soo
    • Journal of the Korea Safety Management & Science
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    • v.13 no.4
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    • pp.81-89
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    • 2011
  • The purpose of this study is to understand the safety factors of the public transportation and recommend the experimental factors of customer satisfaction. The survey consist of 28 questions of 5 factors about users characteristics on roads, railways, ships, and flights. As a result of multiple regression analysis, we knew that there are three potential factors affecting customer satisfaction. The Factors are named 'expected', 'attitude', 'management', and the variable of factors affect customer satisfaction significantly. Therefore, it is good strategy for effective working to improve customer satisfaction that maintain attitude with safety minds, try to specialized management, and creating expectation for safety considering the difference by the type of public transportation. After considering the meaningful result, for the development of policies for customer satisfaction for safety, we have to consider expected, attitude, and management factors of workers and officials that influence customer safety and try to improve the managerial factors considering the characteristics of their own.

A Folded Label Tag for Metallic Environment over UHF Band (금속환경에 적용가능한 UHF대역 라벨 태그의 구현 및 성능평가)

  • Eum, Tae-Hwan;Moon, Byung Hyun
    • Journal of Korea Society of Industrial Information Systems
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    • v.20 no.2
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    • pp.19-24
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    • 2015
  • In this paper, a folded label type RFID tag antenna is designed and produecd for metellic environment over UHF band. Since performance of regular label type RFID tag is seriously degraded for the metallic environment, a folded label tag is proposed to improve the performance. The proposed tag is operating at 910MHz by using inductive T Matching Feed and simulated in HFSS by Ansoft. The actual size is $65{\times}23{\times}3(mm)$ with the impedance of $52-j158{\Omega}$. The maximum distance of identification for the proposed tag is measured as 5.5 meters.

The Effects of Participation Rates in Bakery Promotional Events on Repurchase and Recommendation Intention (베이커리 판촉 행사 참여도가 재구매 의도 및 추천 의도에 미치는 영향)

  • Eum, Tae-Sung;Byun, Gwang-In;Kim, Dong-Jin
    • Culinary science and hospitality research
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    • v.14 no.3
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    • pp.109-122
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    • 2008
  • This study aims to examine the properties of using bakeries based on demographic variables and repurchase intention and recommendation intention according to participation rates in promotional events. First, demographic characteristics and frequency of using bakeries were analyzed. Second, crosstabulation analysis on usability was conducted according to demographic variables. Third, effects of participation rates in promotional events on repurchase intention and recommendation intention were examined. This study could provide the reasons why bakeries should do promotional events, showing their effects on sales. Surveys were conducted with the students of the culinary department and bakery customers to investigate the influence on repurchase intention and recommendation intention according to participation rates in promotional events. As a result, both repurchase intention and recommendation intention showed a significant result. Also, the study aims to improve understanding by analyzing demographic variables on the properties of using bakeries(frequency in use of bakeries, purchase type, bakery type that is preferred, a time slot being made a purchase, objects of purchase, and purchasing price per person) and create data to help the management of a bakery.

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Study on the Validation of Sasang Urination Inventory (SUI) for Analyzing Pathophysiological Symptoms and Diagnosing Sasang Types (배뇨 소증 분석과 사상체질 진단을 위한 사상소변기능검사(SUI)의 타당화 연구)

  • Chae, Han;Lee, Seul;Park, Yu-Gyeong;Lee, Jeongyun
    • Journal of Sasang Constitutional Medicine
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    • v.33 no.3
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    • pp.16-28
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    • 2021
  • Introduction The Sasang Urination Defecation Inventory was developed to analyze Sasang-type specific pathophysiological clinical symptoms, and its revised Sasang Urination Inventory (SUI) illustrated its clinical usefulness in Sasang type differentiation. However, the correlation with established clinical measures for its concurrent validity were not provided yet. Methods Total of 48 healthy university students were recruited to response Urogenital Distress Inventory-6 (UDI-6) and Overactive Bladder Symptom Score (OABSS) of Western medicine along with the SUI of traditional Korean medicine. The correlation coefficients between UDI-6 and OABSS and SUI were acquired with Pearson's correlation, and Analysis of Variance (ANOVA) and Profile Analysis were used to analyze significant differences in SUI subscale profiles of each Sasang types. Results The SUI-HSS of urogenital hypersensitivity correlated positively with OABSS (r=0.442, p<0.01), and the SUI-DIS of urinary discomfort positively with UDI-6 (r=0.289, p<0.05). Interestingly, the SUI-total was correlated positively with age (r=0.326), height (r=0.318) and weight (r=0.304). The SUI-DIS for urinary discomfort of So-Yang (9.48±2.11) type was significantly (p<0.05) higher than that of Tae-Eum (7.2±2.90) type. And SUI subscale profiles of each Sasang type were significantly (Wilks' Lambda=0.792, F=2.723, p=0.034) distinctive to each other. Discussion The acceptable convergent validity of SUI was shown using established measures of urogenital symptoms. The SUI might be used as an objective traditional Korean clinical measure for Sasang type differentiation and urological patients.

Clinical Validation of the Sasang Personality Questionnaire (사상성격검사(SPQ)의 임상 타당화 연구)

  • Jang, Eun-Su;Lee, Soo-Jin;Park, Soo-Hyun;Lee, Si-Woo;Joo, Jong-Cheon;Lee, Mi-Suk;Kim, Yun-Hee;Chae, Han
    • Journal of Oriental Neuropsychiatry
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    • v.23 no.3
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    • pp.23-32
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    • 2012
  • Objectives : The purpose of this study was to validate the Sasang Personality Questionnaire (SPQ), based on the diagnosis of Sasang constitutional medicine clinical specialist. Methods : We performed Sasang type differentiation of 103 college students by certified specialist, and analyzed biopsychological traits of each groups with SPQ, Temperament and Character Inventory (TCI), Positive and Negative Affection Schedule (PANAS) and Body Mass Index (BMI). Results : The SPQ score of So-Yang ($33.1{\pm}0.79$), Tae-Eum ($29.03{\pm}0.67$) and So-Eum ($25.76{\pm}0.98$) Sasang groups showed significant differences from each other. The SPQ showed significant correlation with TCI Novelty-Seeking (r=.346), TCI Harm-Avoidance (r=-.348) and TCI Persistence (r=.346). But the BMI and PANAS did not show significant correlation with SPQ, although the PANAS Positive Affection (r=.332) has significant correlation with SPQ-Behavior. Conclusions : We confirmed the clinical validity of SPQ with clinical specialist and established biopsychosocial instruments. This study would contribute to a more objective diagnosis and studies on biopsychosocial mechanism of Sasang constitutional medicine.