• Title/Summary/Keyword: TTF-1

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Comparison of Overwintering, Biomass, Inorganic N Concentration in Hairy Vetch (Vice villosa Roth) Cultivars (헤어리베치(Vice villosa Roth) 품종별 국내 월동성, Biomass 및 무기태 질소 함량비교)

  • Lee, Sang-Min;Lee, Youn;Lee, Yong-Hwan;Sung, Jwa-Kyung;Yun, Hong-Bae;Choi, Hyun-Sug
    • Korean Journal of Organic Agriculture
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    • v.21 no.1
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    • pp.61-68
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    • 2013
  • This study was conducted to evaluate overwintering of hairy vetch (Vicia villosa Roth), biomass, and inorganic N concentration in soil to verify the adaptability of eight cultivars of hairy vetch into country. Winter survival rate was higher for the hairy vetch cultivars, such as Hungvillosa or Ostsaat, than those of Minnie, Oregon common, and TTF1, which affected amount of biomass of each hairy vetch, with higher biomass observed in Hungvillosa or Ostsaat cultivar. There were no significant difference for the mineral nutrients of each hairy vetch cultivar. Inorganic N concentration in soil was increased at 10 days after mowing by application of Hungvillosa and Ostsaat cultivars that had highly produced N content from the raw materials.

Trophic transfer of organochlorine pesticides through food-chain in coastal marine ecosystem

  • Kim, Seung-Kyu
    • Environmental Engineering Research
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    • v.25 no.1
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    • pp.43-51
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    • 2020
  • The present study was designed to characterize the bioaccumulation of organochlorine pesticides (OCPs) in marine organisms (zooplankton, oyster, crab, and goby) on different trophic level. In the present study, sedentary bivalve (oyster) showed strong correlations in OCPs levels with surface sediment in the study area. This indicates the two compartments can be used as alternative for pollution monitoring of OCPs even in narrow scale in space. Bioaccumulation and trophic transfer of OCPs was strongly associated with their hydrophobicity (i.e., KOW). HCHs with log KOW < 5 did not show any enrichment through food-chain. However, log BAF values of OCPs with log KOW > 5 positioned over the 1:1 lines of log BAF and log KOW of the top predator, indicating the greater fugacities in the higher trophic level and thus the occurrence of biomagnification via ingestion. Based on trophic transfer factors (TTF), more hydrophobic OCPs with log KOW > 5 were enriched by several to several ten times in the highest trophic level relative to the lowest trophic level. This finding can be used in the establishment of marine environmental water quality criteria by considering biomagnification factors (TTF in this study) of OCPs.

A Comparative Study on the Conditioning and Dewaterability of Digested Sludge from Intermittent Aerobic Digestion (간헐포기 소화슬러지의 개량과 탈수 특성에 관한 비교 연구)

  • Kim, Seong Hong;Choi, Young Gyun;Chung, Tai Hak
    • Journal of Korean Society on Water Environment
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    • v.20 no.4
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    • pp.370-375
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    • 2004
  • Synthetic organic polyelectrolytes can be used to condition sludges to enhance their dewaterability. When conditioning biological sludges, the charge on the polymer has a significant impact on the effectiveness of the polymer as a conditioner. The objectives of this investigation were to determine the most effective type and dosage of polymer for conditioning digested sludge prior to dewatering, and to investigate the relationship between dewaterability and particle size. 3 types of digested sludge were used under the different digestion processes like anaerobic digestion, aerobic digestion and intermittent aerobic digestion. CST(capillary suction time), TTF(time-to-filter) and SRF(specific resistance to filtration) were tested as a dewaterability index and the number of particle distribution was analyzed using particle size analyzer. The results indicate that cationic polymer appears to be required for effective conditioning of these 3 types digested sludge and the optimal polymer dosage is about 0.6% of SS. CST and TTF are well correlated with mean particle diameter of which the dimension order is 1.7.

A Study on the Conditioning with Polymer and the Particle Size Distribution of Intermittent Aerobic Digestion Sludge (간헐포기 소화 슬러지의 고분자 응집제에 의한 개량과 입도 분포 변화에 관한 연구)

  • Kim, Hee-Jun;Kim, Seong-Hong;Choi, Jae-Seong
    • Journal of Environmental Health Sciences
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    • v.30 no.3
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    • pp.253-258
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    • 2004
  • Synthetic organic polyelectrolytes can be used to condition sludges to enhance their dewaterability. Intermittent aerobic digestion is an useful digestion technology and has many advantages like neutral pH, low installation cost and easiness to operation. The objectives of this study were to investigate the dewaterability of intemittent aerobic digestion sludge and to find the relationship between dewaterability and particle size distribution change under the conditioning of intermittent aerobic digestion sludge by cationic polyelectrolyte. Digested sludge from intermittent aerobic digestion was used and cationic polyacrylamide polymer was added as a conditioner. CST(capillary suction time), TTF(time-to-filtration) were tested as a dewaterability index and the number of particle distribution was analyzed using particle size analyzer. The results indicate that cationic polyelectrolytes is useful to enhance dewaterability of intermittent aerobic digestion sludge. Mean particle diameter was increased as polymer dosage increased and its value was reached up to 100 mm on the condition of optimal cationic polymer dosage. CST and TTF are well correlated with mean particle diameter when the weighting order is 1.7. By the optimal conditioning with cationic polymer, particles in the filtrate are also reduced significantly and this means that conditioning is helpful to main stream by reducing SS loading from return flow.

Primary Signet Ring Cell Carcinoma of the Lung: A Case Report (원발성 반지세포 폐암종 1예)

  • Cho, Joo Yeon;Lee, Hyun-Kyung;Lee, Sung Soon;Lee, Young Min;Jin, Jae Yong;Lee, Hyuk Pyo;Kim, Joo In;Choi, Soo Jeon;Kang, Yun Kyung;Ro, Jae Yoon;Yum, Ho-Kee
    • Tuberculosis and Respiratory Diseases
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    • v.57 no.5
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    • pp.461-464
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    • 2004
  • Signet ring cell carcinoma (SRCC) of the lung is a rare variant of pulmonary adenocarcinoma. Because the majority of SRCCs in the lung are metastatic tumors from stomach, colon, or breast. The differential diagnosis of primary SRCC from metastatic SRCC is important but may be problematic. Recently, immunohistochemical studies are known to be valuable in determining primary sites of SRCC. Herein, we present a case of primary signet ring cell carcinoma of the lung in a 67-year-old man. Even though radiographic findings of our case were more suggestive of metastatic orgin of SRCC in the lung, we could finally conclude that lung was the primary site of SRCC with the help of immunohistochemical studies (positive TTF-1 and CK7, and negative CK 20) and other diagnostic work up.

Fulvestrant 250mg versus Anastrozole 1 mg in the Treatment of Advanced Breast Cancer: a Meta-Analysis of Randomized Controlled Trials

  • Gong, Dan-Dan;Man, Chang-Feng;Xu, Juan;Fan, Yu
    • Asian Pacific Journal of Cancer Prevention
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    • v.15 no.5
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    • pp.2095-2100
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    • 2014
  • Objective: Most patients with advanced breast cancer experience resistance to endocrine treatment and eventual disease progression. This meta-analysis was designed to compare the efficacy and tolerability of fulvestrant 250mg with anastrozole 1mg in postmenopausal women with advanced breast cancer. Methods: Electronic literature databases (Cochrane Library, Medline, and Embase) were searched for randomized controlled trials (RCTs) published prior to August 2013. Only RCTs that compared fulvestrant 250mg to anastrozole 1mg in postmenopausal women with advanced breast cancer were selected. The main outcomes were time to treatment failure (TTF), time to progression (TTP), duration of response (DOR), clinical benefit rate, and tolerability. Results: Four RCTs covering 1,226 patients (fulvestrant, n=621; anastrozole, n=605) were included in the meta-analysis. Fulvestrant increased the DOR compared to anastrozole (HR =1.31, 95% confidence interval [CI] 1.13-1.51). There was no statistically significant difference between fulvestrant and anastrozole in terms of TTF (HR=1.02, 95%CI 0.89-1.17), complete response (RR=1.79, 95%CI, 0.93-3.43), and partial response (RR=0.91, 95%CI 0.69-1.21). As for safety, there was no statistical significance between the two groups for common adverse events. Conclusion: Fulvestrant 250mg is as effective and well-tolerated as anastrozole 1mg treatment for advanced breast cancer in postmenopausal women whose disease progressed after prior endocrine treatment. Thus, fulvestrant may serve as a reasonable alternative to anastrozole when resistance is experienced in breast cancer cases.

Solid-liquid Separation Characteristics of Membrane Filter Press according to Coagulant Properties of Anaerobic Digestion Waste Water (혐기소화폐액의 응집제 특성에 따른 멤브레인 필터프레스의 고액분리 특성)

  • Han, Seong Kuk;Jung, Hee Suk;Song, Hyoung Woon;Kim, Ho;Ahn, Dae Hyun
    • Journal of the Korea Organic Resources Recycling Association
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    • v.22 no.3
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    • pp.23-32
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    • 2014
  • Recently, it is increase in the processing of organic waste using anaerobic digestion. Therefore, the studies on the processing method for increasing the anaerobic digestion waste water. But it is very difficult to solid-liquid separation, because the characteristics of anaerobic digestion waste water. So this study evaluate solid-liquid separation efficiency of anaerobic digestion sludge using CST(Capillary Suction Time), TTF(Time to Filter). To address this problem, a membrane filter press of the lab scale was produced and the anaerobic digestion wastewater was applied to it. Polymer coagulants were found to be most suitable 7192PLUS and 1T60, It is necessary to minimum injection concentration is 7192PLUS (200 mg/L), 1T60 (100 mg/L). To evaluate dehydration efficiency, it was measured the moisture content of the dehydrated cake and suspended solids of decanted water. As a result, showed that a high removal efficiency of 97.4% when the solid-liquid separation using the membrane filter press. And the moisture content of the dehydrated cake was less than 65%.

Metastatic Adenocarcinoma of the Skin - Immunohistochemical Study (전이성 피부 샘암종의 면역조직화학적 고찰)

  • Choi, Keum-Ha;Jang, Kyu-Yun
    • Journal of Physiology & Pathology in Korean Medicine
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    • v.23 no.5
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    • pp.1041-1048
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    • 2009
  • The development of skin metastasis is usually a morbid prognostic feature although they occur infrequently. Adenocarcinomas account for up to about 70% of all metastatic skin cancer. In general, adenocarcinomas are the most difficult metastatic tumor to accurately identify the primary site because they don't have distinctive histological features. For this reason, immunohistochemistry have been used to help identify the origin of metastatic adenocarcinomas. This study performed immunohistochemical staining with metastatic adenocarcinomas of the skin using a variety of antisera to find out characteristic immunohistochemical findings of them. This study was made upon the 29 cases of metastatic adenocarcinomas of the skin, which had been confirmed histopathologically in Chonbuk National University Hospital from January, 1986 to April, 2006, Paraffin blocks were colledted and homemade tissue arrays were made. We performed immunohistochemical staning using 12 antibodies (MUC1, 2, 5AC, 6, cytokeratin (CK) 7, 20, thyroid transcription factor-1 (TTF-1), estrogen receptor (ER), progesterone receptor (PR), beta-catenin, cox-2, claudin-1). The mean age at the time of diagnosis was 60.7 years and the male to female ratio was 1.2:1.0. The most common primary site was lung, followed by stomach and colorectum. MUC1 was expressed by most colorectal, breast and lung adenocarcinoma. MUC2 was expressed infrequently. MUCSAC was expressed by most gastric and colorectal cancer MUC6 was not specific of any primary site in this series. CK7+/CK20+immunophenotype was observed in gastric, lung, colorectal adenocarcinoma. CK7+/CK20- immunophenotype was observed in breast, lung, endometrial, uterine cervical, bile duct adenocarcinoma, while CK7-/CK20+ immunophenotype was observed only in colorectal adenocarcinoma. This results show the utility of TTF-1 to confirm the pulmonary origin. On the other hand ER and PR were not useful markers to assess the origin of primary tumor in this series.