• 생물정신의학
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• 제4권1호
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• pp.102-107
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• 1997

홍삼사포닌분획의 항불안작용의 양상을 검색하고자 사포닌분획을 사용하여 실험 동물에서 항불안작용을 검색하고 이들의 작용을 benzodiazepine의 대표적 약물인 diazepam의 효과와 비교하여 보았다. 실험동물에서 항불안효과의 검정을 위하여 생쥐에게 각각 상이 한 단일성분 함량을 지닌 여러분획들을 투여 후 elevated plus maze법을 사용하여 항불안효과를 비교, 관찰하였다. 실험결과 홍삼 ginsenoside Rg1, Rf 및 Re 등의 함량이 보다 높은 TSI 분획에서 항불안 효과를 관찰하였다. 중추신경계에 작용하여 진정효과를 나타내는 약물 중 특히 항불안제의 작용에 관여하는 신경전달물질 수용체로 현재까지 가장 주목을 받고 있는 것은 GABA A-benzodiazepine 수용체-chloride통로 복합체에 있는 benzodiazepine 수용체이다. 본 실험결과 관찰한 홍삼 사포닌의 항불안작용의 기전 규명을 위한 접근방법으로 홍삼 사포닌의 benzodiazepine 수용체에 대한 수용체 결합력을 관찰하고자, 흰쥐의 대뇌 피질을 검체로 하여 benzodiazepine 수용체에 대한 [$^3H$] Ro15-1788 결합 실험을 실시하였다. 홍삼 사포닌 분획들은 benzodiazpine 수용체에 결합하는 반응성을 보였으며, ginsenoside Rb, Re 및 Rd등의 함량이 높은 TSIV 분획이 가장 높은 결합력을 나타내었는데, 이 분획에서는 항불안 작용을 관찰할 수 없었다. 이상의 결과에서 볼 때 홍삼사포닌은 항불안작용을 나타내었으며, 이 항불안작용과 benzodiazepine 수용체에 대한 결합력과의 연관성은 관찰되지 않았다.

• 한국안전학회지
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• 제33권2호
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• pp.52-60
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• 2018

This study compares the differences of the fit factor by the order of wearing preference between Particulate filtering facepiece respirators(PFFR) and glasses when participants wore simultaneously and a survey of physical and visual complaint. Recognition level about fit of respirators was investigated and the educational (before- and after-) effect of the fit factor. When participants wore PFFR and glasses, physical complaints were nose pressure, slipping, nose and ear pressure, ear pressure and rim loosen, the most highly physical complaints were nose pressure. Visual complaints were demister, blurry vision, dizziness, visual field, and lens dirty, the most highly visual complaints were demister. But, there was significant difference in physical complaint such as nose pressure(10.3%), slipping (23.0%), nose and ear pressure(14.3%), and rim loosen(16.2%), visual complaint such as visual field(13.8%) and lens dirty(32.4%). For the recognition of fit of respirators, respirators fitness, leak site, an initial point and an object, faulty factor, recognition level was higher. Fit factor was increased after education of proper wearing of respirator. Change of the fit factor was smaller compared to the normal breathing and after 6 actions in case of after education. Questionnaire consisted of general characteristics and physical/visual complaint, recognition of fit. Complaints were measured after the QNFT with multiple choices. Quantitative fit factor was measured by device and compared the result of (before- and after-) educational effect. Also, we selected to 6 actions (Normal breathing, Deep breathing, Bending over, Turning head side to side, Moving head up and down, Normal breathing) among 8 actions OSHA QNFT (Quantitative Fit testing) protocol to measure the fit factors. The fit factor was higher after the training (p=0.000). Descriptive statistics, paired t-test, and Wilcoxon analysis were performed to describe the result of questionnaire and fit test. (P=0.05) Therefore, it is necessary to investigate the quantitative research such as training program and glasses fitting factor about the wearing of PFFR and glasses simultaneously.

• 유통과학연구
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• 제12권2호
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• pp.105-112
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• 2014

Purpose - This research undertakes to understand the trade structures of both China and Japan to strengthen Sino-Japan economic cooperation and examines impediments to trade between the 2 countries to analyze causes which affect trade and to examine improvements in these areas to find out ways of trade expansion. Through this survey of a defined period of time, we can identify the structural factors of trade dependence in the relationship between China and Japan. Research design, data, methodology - The data were collected from Korea Traders Association, Korea Customs Office and UN Comtrade, from which whole table indexes are calculated by author. This research methodology uses trade related indexes to focus on analyzing comparative advantages based on time-series analysis statistics data (2000~2012), by using the analysis index of Trade Intensity Index (TII), Revealed Comparative Advantage Index (RCA) and Trade Specialization Index (TSI). Results - The export ratio for China against Japan was a little higher in 2000 at 2.867 and the export ratio for China against Japan was sustained in 2005. However, it diminished gradually and reached 1.263 in 2012. During the whole period of 2000~2012, the indexes were maintained without any significant change. However, they are still moving closer to -1. Especially, in 2012 it is the closest it has been to -1. Therefore, Japan has a comparative advantage toward export specialization. On the other hand, China has a comparative advantage toward import specialization. For the whole research period, all indexes were much smaller than 1, which means that China has comprehensively had a comparative disadvantage against Japan for the past 10 years when compared to other industries, even though it had improved in 2000. Conclusions - The summary of conclusions based on empirical analysis research are as follows: First, per the Trade Intensity Index of industries between the 2 countries, we can conclude that export ratio index is 2.867, based on the formula, in 2000, which means the export ratio of China against Japan is a little bit higher. Furthermore, the ratios of 2.259 and 1.263 are indicated in 2005 and 2012 respectively which mean the export ratio of China against Japan was maintained in 2005 but was diminishing gradually as the index is 1.263 in 2012. Second, per the Trade Specialization Index of the shipping industry between China and Japan, -0.379 is indicated in 2000, -0.368 in 2005 and -0.568 in 2012. Looking at the whole period of 2000~2012, the indexes were maintained without any significant change. However, they are still moving closer to -1. Especially, in 2012 it is the closest it has been to -1. Third, per the Revealed Comparative Advantage Index of the automobile industry between China and Japan, the RCA indexes in 2005 and 2012 are 0.246 and 0.306 respectively which are still far from 1 even though the index is improved compared to 2000's value of 0.0001. Therefore, the Chinese automobile industry is very much at a comparative disadvantage to that of the Japanese automobile industry.

• 생태와환경
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• 제36권1호통권102호
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• pp.48-56
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• 2003

경북 경산시에서 농업용수로 이용되는 남매지의 3개 정점을 선정하여 2000년 3월부터 2001년 2월까하였다. 다양한 이화학적 환경요인과 식물플랑크톤의 엽록소 a, b, a 농도 및 현존지 매월1회 조사량의 상호관계를 통해 남매지 생태계의 계절적 변화를 파악하였다. 엽록소 a, b와 c의 농도가 6월에 정점 1에서 각각 최고치 (295nlg/1, 9.Smg/1, 48mg/1)를 나타냈고, 식물플랑크톤은 현존량이 정점 3에서 여름에 가장 높았다(7월: $1.7{\time}10^5$scells/1). 수온 분포는 $7{\sim}37.4^{\circ}C$ 범위 이었다. 수소이온 농도는 8월에 $9.9{\sim}10.1$ 범위로 최고치를 나타냈고, 최저는 7로서 9월이었다. SS저는의 최대 및 최 정점 1에서 6월과 11월에 각각 308 mg/1, 4 mg/1이었다. COD와 DOC는 동일한 정점에서 6월에 각각 33mg/1와 16mg/1로 높았다. 식물플랑크톤의 남조류 Microcystis aeruginosa는 7${\sim}$8월에, 녹조류 Scenedesmus acutus는 3${\sim}$5월과 11l${\sim}$1월에, 규조류 Cyclotella orientalis는 10월에 각각가장 우점종하였고, 인산이온과 규산이온의 농도는 여름에 비교적 높은 반면에 가을과 겨울에 전반적으로 낮았다. TSI는 16.6${\sim}$86.4범위로서 전 정점이 부영양화 혹은 과영양화 상태이었고, 유역관리가 선행된 지속적인연구의 필요성이 요구되었다.

• 한국물환경학회지
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• 제36권5호
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• pp.431-444
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• 2020

The relationship between dam construction and water quality has recently come to be considered an important issue. A dam is a physical factor which causes changes to the river system around it. Considering these points, this study was conducted to obtain basic data by analyzing the relationship between water level fluctuations and water quality parameters in the short-term. In terms of methodology, the new construction of the Yeongju Dam (M5) in 2016 was divided into Stage 1 as the lotic system and Stage 2 as the lentic system, with four years in each period, and the water level fluctuations and water quality were analyzed using official data. As a result of this study, M5, a stagnant area in which organic matter and nutrients accumulate, was found to be an important factor in water quality management. In addition, the water level changed rapidly (0.9±0.2 m → 10.9±7.1 m) as the river environment condition was converted from the lotic system to the lentic system. In addition, water quality parameters such as BOD, COD, TOC, and Chl-a significantly changed in the short-term. Further, since the transport of organic matter and nutrients occurred well in the lotic system, sedimentation was expected to be dominant in the lentic system. Therefore, it was determined that when the river flow is blocked, autochthonous organic matter is an important factor for long-term water quality management in the future. This process can increase the trophic state of the water body. As a result of this study, the TSI_KO value was converted from mesotrophic in Stage 1 to eutrophic in Stage 2. Eventually, short-term changes in the river environment will affect not only changes in water level but also changes in water quality. Thus, a comprehensive and strategic approach is needed for long-term water quality management in the future.

• 생태와환경
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• 제37권2호통권107호
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• pp.213-226
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• 2004

본 연구에서는 엽록소 a 농도와 저수지의 수심을 토대로 유형을 분류하고 각 유형에서의 수질특성을 평가하였다. 486개의 저수지를 대상으로 엽록소 a 농도 25 ${\mu}g\;L^{-1}$와 수심 7.5m를 기준으로 4가지 유형으로 분류하였다. 각 호수에서의 연평균 최대 엽록소 a 농도를 기초로 OECD와 TSI 기준에 따라 평가 시 각각 34.3%와 72.8%가 부영양상태였다. 엽록소 a 농도 25 ${\mu}g\;L^{-1}$를 기준으로 구분된 유형들에서 총질소 농도(2배) 보다는 총인 (4배)의 농도차이가 크게 나타났다. TN/TP비를 토대로 할 때 인이 제한 영양염으로 나타났고, 영양상태가 높은 저수지들에서 인에 대한 제한정도가 큰 것으로 나타났다. 엽록소 a 농도가 가장 높은 TYPE II에 포함된 저수지는 상대적으로 노후된 시설이 많고 DA/LA비가 작으며 체류시간이 길고 유역 내 논과 밭으로 이용되는 면적이 넓고 유역에서 발생하는 오염부하가 많았다. 비록 유역면적이 유역내에서의 오염물질 발생부하량과 관련된 요인으로 고려될 수 있으나 수질과의 뚜렷한 상관성이 없었다. 본 연구에서 수심이나 시설물의 노후정도와 같은 형태학적인 특성과 더불어 유역 내의 토지이용형태는 저수지의 수질을 결정하는 매우 주요한 인자로 나타났고 수질 특성을 평가함에 있어 효과적인 인자로 제시되었다.

• 한국수소및신에너지학회논문집
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• 제22권1호
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• pp.1-12
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• 2011

To improve the mechanical properties, such as durabilities and antioxidative characteristics, the covalently cross-linked (CL-) SPEEK (sulfonated polyether ether ketone)/Cs-substituted HPA (heteropoly acid) organic-inorganic composite membranes (CL-SPEEK/Cs-HPAs), have been intensively investigated. The composite membrane were prepared by blending cesium-substituted HPAs (Cs-HPAs), including tungstophosphoric acid (TPA), molybdophosphoric acid (MoPA), and tungstosilicic acid (TSiA) with cross-linking agent content of 0.01 mL. And composite electrolytes composed of Cs-HPAs, prepared by immersion (imm.) and titration (titr.) methods to increase the stability of HPAs in water, were applied to polymer electrolyte membrane electrolysis (PEME). As a result, the proton conductivity of Cs-substituted composite membranes increased rapidly over $60^{\circ}C$ but mechanical properties, such as tensile strength, decreased in accordance with added Cs content. The bleeding-out of Cs-TPA membranes by titration method (50 vol.% Cs) decreased steadily to 2.15%. In the oxidative stability test by Fenton solution, the durability of membranes with Cs-HPA significantly increased. In case of CL-SPEEK/ Cs-TPA membrane, duration time increased more than 1200 hours. It is expected that even though CL-SPEEK/Cs-MoPA membrane shows the high proton conductivity, electrocatalytic activity and cell voltage of 1.80 V for water electrolysis, the CL-SPEEK/Cs-TPA (imm.) is more suitable as an alternative membrane in real system with the satisfactory proton conductivity, mechanical properties, anti-oxidative stability and cell voltage of 1.89 V.

• 유통과학연구
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• 제12권6호
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• pp.21-29
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• 2014

Purpose - This research undertakes to understand the competitiveness of the steel distribution industry of both Korea and China to strengthen Korea-Sino economic cooperation, examines impediments to trade between the two countries to analyze causes which affect trade, and examines improvements in these areas to identify means of trade expansion. Through this survey of a defined period, we can identify the structural factors of trade dependence in the relationship between Korea and China. Research design, data, and methodology - The data were collected from the Korea Traders Association, the Korea Customs Office, and UN Comtrade, from which whole table indexes are calculated. The research methodology uses trade-related indexes to focus on analyzing comparative advantages based on time-series analysis statistics data (2000-2012) by using the analysis index of trade intensity index (TII), the revealed comparative advantage index (RCA), and the trade specialization index (TSI). Results - The export ratio for Korea to China was slightly higher in 2000 at 2.867, and the export ratio for Korea to China was sustained in 2005. However, it diminished gradually, reaching 1.263 in 2012. During the period 2000-2012, the indexes were maintained without any significant change. However, they still remain close to -1. In particular, in 2012 it is the closest it has ever been to -1. Therefore, China has a comparative advantage in export specialization. On the other hand, Korea has a comparative advantage in import specialization. For the research period, all indexes were much lower than 1, which means that Korea has consistently had a comparative disadvantage against China for the past 10 years when compared to other industries, even though it experienced improvement in 2000. Conclusions - The summary of conclusions based on empirical analysis research are as follows: First, per the trade intensity index of industries between the two countries, we conclude that the export ratio index in 2000 is 2.867, which means the export ratio of Korea to China is slightly higher. Furthermore, the ratios of 2.259 and 1.263 held in 2005 and 2012, respectively, meaning that the export ratio of Korea to China was maintained in 2005, but was diminishing gradually as the index in 2012 was 1.263. Second, per the trade specialization index of the steel distribution industry between Korea and China, the value was -0.379 in 2000, -0.368 in 2005 and -0.568 in 2012. Looking at the whole period of 2000-2012, the indexes remained without any significant change. However, they are still moving closer to -1. In particular, in 2012 it is the closest it has ever been to -1. Third, regarding the revealed comparative advantage index of the steel distribution industry between Korea and China, the RCA indexes in 2005 and 2012 are 0.246 and 0.306, respectively, which are still far from 1, even though the index has improved compared to the 2000's value of 0.0001. Therefore, the Korean steel distribution industry is at a significant comparative disadvantage to that of the Chinese steel distribution industry.

• 통상정보연구
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• 제16권2호
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• pp.297-318
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• 2014

본 연구는 통상진출측면에서 UAE 의약품 시장의 점유율 확대 전략을 중심으로 시장세분화, 목표시장 결정, 제품 위치선정과 아울러 목표시장 내에서의 시장촉진 관리를 내용으로 문헌연구를 실시하였다. 기본적으로 STP전략과 Marketing Mix전략의 개념을 적용하여 본 연구의 실무적 시사점을 도출하였다. 우리나라 의약품산업은 국내의 다양한 제도적 제약으로 인한 국내시장 성장의 확대에 한계를 가지고 있다. 한편 UAE 의료산업은 지속적인 유가 상승에 따른 경기의 활성화와 정부의 적극적인 지원 정책으로 급성장하고 있다. UAE 정부는 의료시설 확충과 의료수준 향상을 위해 2014년 의료산업에 1600억 달러의 투자를 계획하고 있다. UAE의 의료부문은 각 에미리트별로 단독적인 규제 체제를 갖추고 있다. UAE는 해외 노동자 유입으로 높은 인구증가율을 보이고 있는데, 지난 30년 동안 UAE 거주인구는 약 7배가 증가했다. UAE 정부는 의료서비스 질을 개선하기 위해 민간부문과 공공기간의 파트너십(PPP) 체결을 장려하며 외국인 직접투자에도 규제가 없으므로 우리 기업으로서는 거대 다국적 기업과 무한 경쟁을 준비해야 하는 시점에서 이러한 분석결과는 의약품 수출활성화 측면의 환국의 비즈니스환경 분석과 UAE 시장에 대한 진출전략 측면에서 시사점을 도출하였다는 점에서 실학적 가치를 찾을 수 있다. 또한, 해외진출 활성화와 더불어 한국의 취약한 의약품 산업 개발을 위한 지속적인 전략 개발의 타당성을 확보해준다는 측면에서 학문적 의미가 있다.

• 한국입자에어로졸학회지
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• 제16권2호
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• pp.49-59
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• 2020

Various devices have been developed to the measurement of particulate matter pollutants, and Optical Particle Counter (OPC) that can be easily and quickly measured is widely used lately. The measured value by OPC is converted to weight concentration using the correction factor (CF). The calculation of CF is very important to improve the reliability and accuracy of OPC. In this study, the CF calculation study of light scattering laser photometer (model 8533, TSI) was carried out to measure in the atmospheric environment using 2 gravimetric devices and 3 light scattering laser photometer devices. Regression analysis and Tukey tests were used to significance the test of measurement devices. Measurements were carried out twice. There was a comparative analysis of measurement data between light scattering laser photometer and gravimetric devices in 1st measurement, and then the Evaluation of PM2.5 concentration corrected by CF performed in 2nd measurement. As a result of the significance analysis between light scattering laser photometer and gravimetric devices, the correlation between the same method was high, but the correlation between different methods was low. CF was calculated as 0.4258 based on the measurement results, and it is a similar level to previous studies at home and abroad. It is expected that these results can be used as basic data in the future study for air quality measurement research using light scattering laser photometer. Also, in order to improve the accuracy of the measurement techniques and the development of technology in the atmospheric environment, CF calculation research should be conducted continuously.