• Title/Summary/Keyword: TSH

Search Result 300, Processing Time 0.028 seconds

A Certification Protocol based on Broadcast Invalidation Approach (브로드케스트 무효화 기법을 이용한 인증 프로토콜)

  • Sung-Ho Cho;Min-Goo Kang
    • Journal of Internet Computing and Services
    • /
    • v.3 no.6
    • /
    • pp.79-89
    • /
    • 2002
  • The performance of OCC is very sensitive to the transaction abort rate, Even if the abort probability can be reduced by re-ordering, most of re-ordering schemes have space overhead in maintaining a graph or histories, In this paper, we proposed an efficient re-ordering scheme based on a broadcast invalidation mechanism. Our scheme, called CBI, can reduce the abort probability without space overhead in maintaining a graph or histories, By simulation studies, we showed that CBI reduced the abort rate and unnecessary operations, Additionally, we showed that CBI outperforms not only BTS but also TSH with low space overhead.

  • PDF

Studies on Setting up of Radioimmunoassay System of Thyroid Stimulating Hormone (갑상선자극(甲狀腺刺戟)호르몬의 방사면역측정법(放射免疫測定法) 확립(確立)에 관한 연구(硏究))

  • Kim, Jae-Rok;Park, Kyung-Bae;Awh, Ok-Doo
    • The Korean Journal of Nuclear Medicine
    • /
    • v.20 no.1
    • /
    • pp.75-83
    • /
    • 1986
  • Various TSH RIA kit components were prepared. Conditions for $^{125}I$ labelling of h-TSH were optimized by diminishing the amount of chloramine-T, ertending reaction time and lowering reaction temperature. Yield, specific activity, and immunological activity could be maintained moderately under such mild reaction conditions. The mixture of polyethyleneglycol(PEG) and second antibody worked effectively as a B/F separation agent. Even though the mixture was made with more diluted PEG and second antibody than those of using the sole component separately, the tine required for the B/F separation was shorter in case of using the mixture. The sequential saturation technique was efficient than those of applying ordinary equilibrium saturation technique in assay sensitivity and assay precision points of view.

  • PDF

Effect of Acid Hydrolyzates of Ginseng Saponins on Lipid Metabolism in Rat Epi didymal Adipose Tissue (인삼Saponin의 산가수분해물이 Epididymal Adipose Tissue의 지방대식에 미치는 영향)

  • Do, Jae-Ho;Kim, Sang-Dal
    • Journal of Ginseng Research
    • /
    • v.6 no.2
    • /
    • pp.123-130
    • /
    • 1982
  • Studies were carried out to clarify the effect of ginsenoside-Rbl -Rbr and acid hydrolyzatps of ginsenoside-Rbl, -Rb2 (HRbl, HRbf) on lipolysis and lipogenesis induced by epinephrine, glucagon, ACTH (adrenocorticotrophic hormone), TSH (thyroid-stimulating hormone) and insulin in rat adipose tissilr. HRbl , HRb2 slightly inhibited lipolysis induced by epinephine. glucagon and TSH. ACTH-induced lipolysis in fat tissue slices was significantly inhibited by ginsenoside -Rbl, -Rb2, HRbl and HRb2, particulary HRb2. None of ginsenoside-Rbl, -Rb2, HRbl and HRb2 accelerated insulin-stimulated lipogenesis in fat calls. Among ginseng products, extract powder (freeze dried), extract powder (spray dried), red ginseng powder inhibited ACTH-induced lipolysis in adipose tissue slices, but red ginseng extract not affect them.

  • PDF

Effects of Cistanche Deserticola on Thyroid Function in Hypothyroidism Rat Model Induced by PTU(6-Propyl, 2-thiouracil) (육종용이 PTU로 유발된 갑상선 기능저하증 동물모델에 미치는 영향)

  • Lee, Seung-Jin;Paik, Sun-Ho;Ahn, Se-Young;Lee, Byung-Choel;Ahn, Young-Min
    • Journal of Physiology & Pathology in Korean Medicine
    • /
    • v.25 no.6
    • /
    • pp.989-995
    • /
    • 2011
  • Hypothyroidism is the most common disease in the endocrine system. Cistanche Deserticola has been used traditionally in the treatment of kidney deficiency and Yang deficiency syndrome. In this study, we investigated the therapeutic effects of Cistanche Deserticola on Hypothyroidism rat model induced by PTU. 24 Two-month-old Sprague-Dawley male rats were divided into 4 groups : 1) normal(n=6), 2) PTU-induced hypothyroidism control(n=6), 3) hypothyroidism rat treated with Cistanche Deserticola(n=6), 4) hypothyroidism rat treated with levothyroxine(n=6). PTU was administered for 4 weeks. Cistanche Deserticola and levothyroxine was administered 2 weeks after PTU was initiated for a total duration of 2 week. Body weights were checked every week and after 4 weeks, biochemical analysis was performed and T3, T4 and TSH were measured by ELISA kits. In comparison with the normal group, the control group showed hypothyroidism with lower T3, T4 level and higher TSH level. In the Cistanche group the level of T4 was significantly increased and TSH level was significantly decreased. There was no significant difference in biochemical labs and weight between the Cistanche group and the control group. These findings suggest that Cistanche Deserticola could help the production of thyroid hormones under PTU suppression. And there is no harmful effect on liver and kidney function, and other metabolism. According to these results Cistanche Deserticola could be an useful agent for treating hypothyroidism.

Risk Factors of Hypothyroidism after Hemithyroidectomy for Benign Thyroid Disease in Korea (양성 갑상선 질환으로 편측 갑상선 절제술을 시행한 후 발생되는 갑상선 기능 저하증에 대한 위험인자)

  • Lee, Seok-Jae;Kim, Kyung-Tae;Cho, Byung-Han;Lim, Jae-Yol;Kim, Young-Mo
    • Korean Journal of Head & Neck Oncology
    • /
    • v.26 no.2
    • /
    • pp.212-215
    • /
    • 2010
  • Objectives:There are various reports for incidence and risk factors of hypothyroidism after hemithyroidectomy for benign thyroid disease. The reported incidence rate varies from 5.0 to 41.9%. Moreover, there are few reports about this in Korea. So, our objective is to identify the incidence and possible factors contributing to hypothyroidism after hemithyroidectomy in Korea. Subjectives and Methods:We reviewed medical records of patients who underwent hemithyroidectomy between 1999 and 2007 years. We enrolled 80 patients. The incidence of postoperative hypothyroidism was based on thyrotropin values and clinical symptoms. And all patients were evaluated for age, gender, serum thyrotropin(TSH) levels, serum free T4, weight of resected thyroid tissue and associated thyroiditis. Results:Nine of 80 patients(11.3%) became biochemically hypothyroid postoperatively. Six of 9 hypothyroid patients were diagnosed within 2 months of operation. The mean preoperative TSH level was $2.12{\pm}0.96mIU/L$ in hypothyroid and significantly different from $1.33{\pm}0.77mIU/L$ in euthyroid patients(p<0.05). There were no significant differences in age, gender, weight of resected thyroid tissue, preoperative free T4 and associated thyroiditis. Conclusion:A minority of patients became hypothyroid after hemithyroidectomy. Hypothyroidism following hemithyroidectomy occurred in patients with higher preoperative TSH levels.. The screening test for postoperative hypothyroidism should be performed from month to year after operation.