• Biomolecules & Therapeutics
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• v.8 no.1
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• pp.44-52
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• 2000

SKP-450 which is $K^{+}$ channel opener, When given into duodenum, exhibited the decline of urine flow accompanied with the decrease of glomerular filtration rates (GFR), renal plasma flow (RPF), N $a^{+}$ and $K^{+}$ excreated in the urine ( $E_{Na}$ , $E_{K}$) and the increase of $K^{+}$N $a^{+}$ratios, and then appeared the significant fall of mean arterial pressure (MAP) and unchanged of reabsorption rates of N $a^{+}$, $K^{+}$ in renal tubules ( $R_{Na}$ , $R_{K}$). SKP- 450 injected into the vein elicited the decline of urine flow along with the reduction of $E_{Na}$ , $E_{K}$, and the increase of $R_{Na}$ , $R_{K}$ and $K^{+}$M $a^{+}$ ratios. SKP-450 administered into a renal artery produced diuretic action along with the increase of $E_{Na}$ , $E_{K}$ and the decrease of $R_{Na}$ , $R_{K}$ in experimental kidney, whereas produced the same aspect to intravenous SKP-450 in the control kidney. Above results suggest that SKP-450 possess both diuretic action in the kidney and central antidiuretic action in dog.tic action in dog.tion in dog.

• Korean Institute of Interior Design Journal
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• no.6
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• pp.53-62
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• 1995

This research aims at proving the fact that the forms, spaces and many other design concepts of Modernism are much related with the changes of materials, struc-tures, and the way of construction as well as the idealis-tic and aesthestic things through the history of steel, one of the most important materials of the style. The meaning steel has in the modern architecture can be studied in the structure and industrial production system. 1) Steel frame broadened the range of understanding the space and created the new form through the skeleton/skin structure by reinterpreting the existing space fac-tors while it was being adopted to the architecture. Walls could be freed from the traditional function of bear-ing wall and roofs gave the transparancy to the interior by being linked with the glass. Posts lost the function which confines the space in the frame of the grid system and gave the flexibility to the interior due to the economical materials. These changes made the movable partition, screen with various materials and the system furniture which divides the space more important. 2) In the aspect of the industrialized architecture, it be-came the moment that the most of the archtectural com-posing parts were in mass production as they were standarized, high qualified, and generalized by the indus-trial characteristics of steel, and the specialization of structure and cladding, but the neither of the efforts to make the building itself by mass production or to standarize it was fulfilled. The high-tech architecture which borrows its archtectural manifestation from the high technology, however, is consistently paying efforts on such industrialization.

• Anxiety and mood
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• v.6 no.2
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• pp.93-101
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• 2010

Research on obsessive-compulsive disorder (OCD) has advanced substantially since the DSM-IV was published in 1994. It is time to reexamine the nosology of this disorder, reviewing conflicting views regarding the classification as well as subtypes and specifiers of OCD. Although there is ongoing debate, OCD experts have suggested that OCD be retained in the section related to anxiety disorders and also that along with OCD, this section include obsessive-compulsive spectrum disorders (OCSD), a group of disorders closely related to OCD. A combined 'anxiety and obsessive-compulsive spectrum chapter' has also been proposed to include OCSDs. A growing body of scientific data has provided empirical support for the inclusion of a 'tic-related' subtype of OCD in the DSM-V. However, it remains controversial as to whether to introduce OCD symptom dimensions as specifiers as well as items in the diagnostic criteria. With regard to compulsive hoarding, there has been sufficient evidence to recommend that it be classified in the DSM-V as a separate disorder. Much work remains in order to ensure that the DSM-V is as evidence based as possible. It is necessary to strive toward integrating the biological and psychological data related to OCD and OCSD based on their endophenotypic features.

• Journal of the Korean Society of Food Science and Nutrition
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• v.19 no.1
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• pp.35.1-52
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• 1990

An ecological survey of early childhood nutrition and parasitic infection was undertaken among 102 children aged 3 to 6 atteending the three day care centers of Hongcheon county Kangwon province between June and July 1987. In frequency of skipping meal 35.1% of subjects often skipped breakfast ; 3.1% skipped breakfast every day. About 53% of those children complained of having poor appetite at breakfast. The percentage of children having meals with all the family members was 94.8% for breakfast and 97.9% for evening meal. In eatinf behavior 20.6% of the subjects had meals while watching TV; 21.6% moved around during a meal ; 22.1% hadmeal talking loudly ; 35.1% had quiet meal. Approximately 63% of children used chopsticks and others used fork or spork. Concerning of dietary staple boiled rice was dominant. The diversity of food selection by those children was so linmited that simply only one or two items of side-dishes and /or souop were taken at home. Subjects liked yorgurt milk lavers fruits and Ramyun in contrast to the loweest preference for fermented fist aroma-tic vegetables butter and margarine. The positive prevealence of parasitic infection was 35.5% including than that observed in any other rural areas. Incidence of Fibricola seoulenis was caused by local habit of eating hibernate frogs without enough boiling.

• Proceedings of the Korean Institute of Information and Commucation Sciences Conference
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• 2008.10a
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• pp.479-482
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• 2008

사고력 신장 교육은 정보영재를 위한 교육과정 및 내용 중에서 매우 중요한 목표이다. 이 논문에서는 정보영재 교육에서 중요성이 증대되는 사고력 신장 교육에 적합한 교수-학습 프로그램을 제시하여 적용하고 분석하는 방안을 마련한다. 사고력 신장 교육을 구성하는 영역별 교육 내용에 포함되는 여러 가지의 문제들에 공통적으로 적용할 수 있는 모형으로서 AND/OR 트리에 기반을 둔 교수-학습 모형을 제시한다. 이 논문에서 제시된 AND/OR 트리형 교수-학습 모형을 정보영재의 현장 교육에 도입하기 위하여 tic-tac-toe 게임 문제를 예로 들어 적용 방안을 제시하며, 그 적용 결과를 분석하여 교육 프로그램 개발의 타당성을 검증한다. AND/OR 트리형 교수-학습 모형에서는 AND 트리와 OR 트리가 결합된 형태의 트리 구성과 그에 따른 트리 탐색을 주요 학습 내용으로 하는 고도의 사고력을 필요로 하는 학습 단계를 필요로 한다.

• Proceedings of the Korean Society for Agricultural Machinery Conference
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• 1996.06c
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• pp.755-764
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• 1996

A multispectral imaging system with selected wavelength optical filter was demonstrated feasible for food safety inspection. Intensified multispectral images of carcasses were obtained with visible/near-infrared optical filters(542-847 nm wavelengths) and analyzed. The analysis of textural features based on co-occurrence matrices was conducted to determine the feasibility of a multispectral image analyses for discriminating unwholesome poultry carcasses from wholesome carcasses. The mean angular second moment of the wholesome carcasses scanned at 542 nm wavelength was lower than that of septicemic (P$\leq$0.0005) and cadaver(P$\leq$0.0005) carcasses. On the other hand, for the carcasses scanned at 700nm wavelength , the feature values of septicemic and cadaver carcasses were significantly (P$\leq$0.0005) different from wholesome carcasses. The discriminant functions for classifying poultry carcasses into three classes (wholesome, septicemic , cadaver) were developed using linear and quadr tic covariance matrix analysis method. The accuracy of the quadratic discriminant models, expressed in rates of correct classification, were over 90% for the classification of wholesome, septicemic, and cadaver carcasses when textural features from the spectral images scanned at the wavelength of 542 and 700nm were utilized.

• Journal of Physiology & Pathology in Korean Medicine
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• v.16 no.3
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• pp.542-546
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• 2002

The purpose of this study was to investigate the effect of 2-thioDMNQ-S160, shikonin analogue isolated from Uthospermum Erythrorhizon, on the antitumor activity. In the present study, 2-thioDMNQ-S160 exhibited a significant cytotoxicity against L1210, A549, U937, and 816-BL6 cell lines with IC/sub 50/s of 2.4ug/ml, 2,0ugjml. 4ug/ml and 20 ug/ml, respectively. 2-ThioDMNQ-S160 strongly inhibited adhesion of B16-BL6 cells to gelatin and matrigel coated matrices. Also, 2-ThioDMNQ-S160 exhibited anti-invasive effect of B16-BL6 cells. The T/C% was 123 % in 2-ThioDMNQ-S160 treated group in S-180 bearing ICA mice. These results suggested that 2-thioDMNQ-S160 might be a potent candidate of cancer drug.

• Journal of the Korean Society for Precision Engineering
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• v.16 no.8
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• pp.9-15
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• 1999

Die-sinking electrical discharge machining(EDM) for conductive ceramic matrix composite(CMC) of Tic/$Al_2O_3$ was experienced with addition of ultrasonic emission, and the results were compared with ones obtained by the EDM only. From this experimental study, the values of material removal rate(MRR) and surface roughness($R_{max}$), scanning electron microscope(SEM) micrographs, and weibull probability distribution of bending strength for the specimens were obtained and compared. The trend of MRR was found to be increased slightly with the current and the duty factor for both EDM only and EDM with ultrasonic emission. The MRR values were found to be increased for EDM with ultrasonic emission. The SEM micrographs of EDMed surface by under various operating conditions showed less micro cracks in various places. Although smaller bending strength value was obtained by EDMed surface with ultrasonic emission by weibull probability distribution analysis of bending strength.

• Korean Journal of Air-Conditioning and Refrigeration Engineering
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• v.20 no.8
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• pp.547-555
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• 2008

The effects of paper properties such as density, air permeability, water vapor transmission rate on the thermal performance of plate-type enthalpy exchanger were experimentally investigated. Papers having different properties were made from the same pulp by calendering or refining. Enthalpy exchanger samples were made from the papers, and were tested according to the standard test procedure (KS B 6879). Effective efficiencies were obtained, which accounted for the air leakage between supply and exhaust streams. Results showed that paper density affected the sensible heat transfer of the samples. Sensible heat transfer increased with density of the paper. It was also shown that effective efficiency of latent heat transfer was approximately the same independent of the samples, which suggests that papers made of the same pulp show similar water vapor transmission characteristics independent of the degree of calendering or refining. Best performance was obtained for the sample having highest paper density and moderate water vapor transmission ratio.

• Proceedings of the SAREK Conference
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• 2008.06a
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• pp.414-418
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• 2008

The effects of paper properties such as density, air permeability, water vapor transmission rate on the thermal performance of plate-type enthalpy exchanger were experimentally investigated. Three enthalpy exchanger samples having different properties were made, and were tested according to the standard test procedure (KS B 6879). Effective efficiencies were defined, which accounted for the air leakage between supply and exhaust streams. Results showed that paper density affected the sensible heat transfer of the samples. Sensible heat transfer increased with density of the paper. It was also shown that water vapor transmission rate alone was not a proper indicator for the efficiency of latent heat transfer. Air permeability should also be considered for adequate evaluation of the latent heat transfer. Best performance was obtained for the sample having highest paper density and moderate water vapor transmission ratio.