• The Journal of Korean Medicine
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• v.24 no.4
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• pp.11-18
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• 2003

Purpose : This study examined the effect of Tongbiyeum (TBY) on rats with fatty livers. Methods : After administration of TBY extracts to rats with fatty livers, body weight, liver weight, serum, cholesterol, TG, HDL-cholesterol were measured, and histopathological changes were observed. Results : In proportion to density, TBY decreased liver weight and serum TG levels and suppressed fat accumulation and liver cell death, but increased serum HDL levels in comparison with those of controls. Conclusion : TBY might be considered to be used to control fatty liver by inhibiting absorption and storage of TG.

• Journal of Korean Biological Nursing Science
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• v.19 no.2
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• pp.107-112
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• 2017

Purpose: The purpose of this study was to identify the lipid profile ratios as factors affecting disease progress in patients with high-grade primary brain cancers undergoing concurrent chemoradiotherapy (CCRT) and adjuvant chemotherapy. Methods: The levels of lipid profile ratios were evaluated by looking at the total cholesterol (TC) to high-density lipoprotein (HDL)-cholesterol (TC/HDL-c), low-density lipoprotein (LDL)-cholesterol to HDL-cholesterol (LDL-c/HDL-c), and triglycerides to HDL-cholesterol (TG/HDL-c). This descriptive research was conducted 7 months after the initiation of CCRT and adjuvant chemotherapy. Results: A total of 36 patients with newly diagnosed primary malignant brain cancer were included in the study. The levels of lipid profile ratios such as TC/HDL-c, LDL-c/HDL-c, TG/HDL-c were significantly different between the patients with and without disease progress at 7 months after initiation of CCRT and adjuvant chemotherapy. Conclusion: The lipid profile ratios were indicators affecting disease prognosis with tumor-related factors at 7 months after initiation of CCRT and adjuvant chemotherapy. Therefore, lipid profile ratios indicating hyperlipidemia in patients with high-grade brain cancers should be carefully monitored during and after cancer-related therapy.

• Journal of Nutrition and Health
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• v.17 no.3
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• pp.217-223
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• 1984

Twenty three healty women on self - selected diet were given 800IU of tocopherol daily for 4 weeks. The levels of tocopherol in plasma and red blood cells( RBC ) and total choles terol, TG, HDL- chol, HDL subfractions and lipoprotein pattern in serum were determined pre-and postregimen at 2 and 4 weeks. No significant change was noted in VLDL, LDL, HDL fraction and LDL/HDL ratio separated by electrophoresis, even though HDL fraction was decreased at 2 wk but slightly increased at 4 wk. There were also no significant changes in the relative amount of HDL-chol and VLDL-chol when cholesterol content of each lipoprotein fraction was assayed. A transient increase in LDL-chol was observed at 2 wk but returned to the pretreatment level. Plasma and RBC tocopherol levels were significantly ( p ^lt;0.05 ) increased and decreased respectively, at both 2 and 4 wk, and LDL-chol was positively correlated to plasma tocopherol level ( p<0.05 ) but not to RBC tocopherol. However HDL-chol fractionated by heparin-Mn was increased at 2 and 4 wk by a significant increase in $HDL_{2}$-chol but no change in $HDL_{3}$-chol, which resulted in a significant reduction of $HDL_{3}$/HDL ratio and increase of $HDL_{2}/HDL$ and $HDL_{2}/HDL_{3}$ ratios. HDL- chol was negatively correlated to the levels of LDL-chol ( p<0.05), VLDL-chol (p<0.01), and T-chol/HDL ratio ( p<0.01 ). Serum TG was significantly decreased ( p <0.05 ) but total cholesterol was decreased only at 4 weeks.

• Korean Journal of Community Nutrition
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• v.13 no.1
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• pp.100-110
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• 2008

Recently, a lot of epidemiological studies revealed that low HDL-cholesterol level was a better predictor of risk for coronary heart disease than total cholesterol. This study investigated the anthropometric parameters, clinical blood indices, and dietary factors influencing serum HDL-cholesterol level by using a cross-sectional study for Korean female college students. The subjects were 94 female college students. They were divided into three groups according to their serum HDL-cholesterol levels, low HDL-cholesterol (<50 mg/dL, n=20), medium HDL-cholesterol (50 $\leq$, < 60 mg/dL, n=39) high serum HDL-cholesterol groups (60 $\leq$ mg/dL, n = 35). This study examined their demographic data and dietary intake throughout a questionnaire. Clinical blood indices were measured using an automatic blood chemistry analyzer (Selectra E), after 12 hours of fasting. BMI, body weight, fat mass, and waist circumferences were significantly increased according to low serum HDL-cholesterol levels. Serum lipid analysis showed a significantly higher level of TG, LDL-/HDL-Ratio, atherogenic index in the low HDL-cholesterol group. Serum levels of GPT, uric acid and alkaline phosphatase in the low HDL-cholesterol group were significantly higher than in the other group. The average consumption of energy was 1627 kcal and 77.76% of estimated energy requirement (EER). The mean ratio of calories from carbohydrate: protein: fat was 57:15:28. The low HDL-cholesterol group was significantly higher than the other groups in eggs, fat and oils consumption. Interestingly, milk and diary products consumption of low HDL-cholesterol group was half (p < 0.05) of those of the other groups. In conclusion, serum HDL-cholesterol levels appeared to be decreased by increasing BMI, fat mass, waist circumference, and serum TG level. In addition, some dietary factors seemed to be related to serum HDL-cholesterol levels. However, further research is needed to elucidate the exact relationship between serum HDL-cholesterol level and dietary factors.

• Journal of Nutrition and Health
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• v.29 no.9
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• pp.1035-1041
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• 1996

The study was undertaken to examine the levels of serum lipids and the correlations between serum lipid levels and other factors(nutrient intakes, anthrometric measurement, blood pressure, drinking, smoking). The participants in this study were healthy volunteers over the age of 40 residing in Whachon area, Kang-Wan Do. The level of serum TG was higher in males than in females, particularly in age of 40(209.8mg/dl$\pm$154.9, p<0.05). The HDL-c/total cholesterol ratio(HTR) in males was the lowest(0.23$\pm$0.07, p<0.05) in age of 40 and in females was the lowest(0.25$\pm$0.1) in age of 60 and over. LDL-c/HDL-c ratio(LHR) was the highest (males 3.64$\pm$6.29, females 3.28$\pm$3.03) in age of 40 in both sexes. In the age of 40-59, serum TG, total cholesterol and LDL-cholesterol and HDL-cholesterol tended to increase with BMI. Serum TG showed positive correlation with drinking (r=0.026, p<0.001) and BMI (r=0.2096, p<0.01). BMI was negatively correlated with HTR(r=-0.2242, p<0.01) and HDL-cholesterol (r=-0.2054, p<0.01).

• Journal of the Korean Society of Physical Medicine
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• v.9 no.3
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• pp.301-305
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• 2014

PURPOSE: The purpose of this study was to determine the optimal thresholds of serum lipid level related to hypertension according to age in Korean adults. METHODS: In total, 564 adults who visited the health examine center in general hospital were included. The blood pressure and lipid profiles of low density lipoprotein cholesterol(LDL), high density lipoprotein cholesterol (HDL), triglyceride(TG) were measured. Receiver operating characteristic (ROC) curve were used to establish optimal thresholds between blood pressure and lipid profiles. RESULTS: The optimal TG cutoff value were 110.50(mg/dl) in the 18-39 and 81.50(mg/dl) in the 40-59 age group, and optimal cutoff value of LDL were 126.50(mg/dl) in the 40-59 age group and 111.00(mg/dl) in the 60 and over age group. There was a negative correlation between HDL and hypertension, a higher HDL decreased hypertension. The optimal cutoff value of HDL was 49.50(mg/dl) in the 18-39 age group. CONCLUSION: The thresholds of hypertension were lower in LDL and TG with aging. This result indicated that elderly people needs to concern more about their lipid profiles to maintain healthy cardiovascular function.

• The Journal of the Korea Contents Association
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• v.20 no.11
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• pp.525-533
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• 2020

The purpose of this study is to analyze how the ten-week complex exercise program for obese postpartum women affects their metabolic syndrome related risk factors (HDL-C, TG, Glucose, blood pressure, and waist circumference) and adipocytokines (Leptin and Adiponectin). The study subjects were 14 women who passed less than 40 months after their child birth, among whom seven were assigned to complex exercise group and seven to control group. The complex exercise program consists of rhythm dance aerobic exercise and resistance exercise. It has been performed twice a week for 10 weeks, and 80 minutes for each session. For data analysis, Mann Whitney U-test, Wilcoxon test, Spearman correlation analysis were conducted. As a result, the groups had no difference in all of the metabolic syndrome related risk factors before and after the program. Regarding intra-group difference, the complex exercise group significantly increased HDL-C, and significantly decreased TG, Glucose, and waist circumference, and the control group signfiicantly increased TG and Glucose. According to the analysis on adipocytokines, in terms of intra-group difference, the complex exercise group significantly increased Adiponectin after exercise. With regard to the correlations between metabolic syndrome related risk factors and adipocytokines, HDL-C and Glucose had a correlation with Adiponectin.

• Journal of the Korea Academia-Industrial cooperation Society
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• v.11 no.12
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• pp.4843-4853
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• 2010

The purpose of this study was to investigate the association of blood pressures, hematological and biochemical properties of blood according to the degree of obesity in health checkup examinees. Study subjects were 3,731 adults of 20 years and over (2,312 males, 1,419 females), who underwent health package check-up at the Korea Health Management Association from Jan. 2007 to Dec. 2009. As a result, the rates according to the degree of obesity of study subjects were 4.6% in low weight group, 44.3% in normal weight group, 25.0% in over weight group and 26.1% in obesity group. The over weight group were significantly higher in 40's age group than other groups, and the obesity group were significantly higher in 50's age group than other groups. The abnormal rates of SBP, DBP, TG, TC, HDL-C, LDL-C, ALT, AST in male were significantly higher than that of female. With respect to degree of BMI, the abnormal rates of SBP, DBP, TG, TC, HDL-C, LDL-C, ALT, AST, GGT, ALP were significantly increased with higher level of BMI. The age-adjusted odds ratio in the abnormal level of SBP, DBP, TG, TC, HDL-C, LDL-C, AST, ALT and GGT were significantly increased in overweight group and obese group than that of normal weight group.

• Journal of the Korea Academia-Industrial cooperation Society
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• v.15 no.8
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• pp.5009-5022
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• 2014

The purpose of this study was to obtain the serum lipid levels according to the lifestyles, and examine the influence of lifestyles on the serum lipid levels among adults who examined the health checkup in an university hospital. The subjects for this study were 4,112 adults who underwent medical examinations at the health center of a university hospital in Daejeon city from Jan 2012 to Dec 2013. The lifestyles and serum lipid levels of study subjects were obtained from self-recorded questionnaires and medical examination charts of the hospital. As a result, the mean values of the serum lipid levels (TC, HDL-C. LDL-C and TG) and atherogenic index (AI) of the study subjects showed a significantly difference according to the lifestyle, such as age, alcohol consumption, smoking, regular exercise, overeating and meat consumption in both sexes. The TC, HDL-C. LDL-C, TG and AI showed a positive correlation with age, AUDIT score, but the HPI score showed a negative correlation in both sexes. In the age-adjusted odds ratio, the risk ratio of an abnormality of TC, HDL-C. LDL-C, TG and AI increased significantly because there was an increase in the group of everyday overeating and meat consumption, smoking group, no exercise group, and low HPI group than their respective counterparts in both sexes. The above results suggested that the serum lipid levels of the subjects was closely related to increasing age, and lifestyles, such as alcohol consumption, smoking, regular exercise, overeating, and meat consumption.

• Journal of the Korea Academia-Industrial cooperation Society
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• v.16 no.2
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• pp.1145-1152
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• 2015

This study examined the serum lipid levels according to the obesity indices, and obtained the relationship between obesity indices and serum lipid levels among adults who underwent a health checkup in a university hospital. The subjects for this study were 4,112 adults aged 18 to 77 years who underwent medical examinations at the health center of a university hospital in Daejeon city from Jan 2012 to Dec 2013. The serum lipid levels (TC, HDL-C, LDL-C, TG, AI) and obesity indices (height, weight, waist circumference, body fat rate, BMI, WHR WSR) of the study subjects were surveyed from self-recorded questionnaires and medical examination charts of the hospital. As a result, the serum lipid levels (TC, HDL-C, LDL-C, TG, AI) of the study subjects were increased significantly with higher level of obesity indices (WC, body fat rate, BMI, WHR WSR) in both sexes. The TC, LDL-C, TG, and AI showed that positive correlated with the WC, body fat rate, BMI, and WSR in both sexes, but HDL-C was negatively correlated with the WC, body fat rate, BMI, and WSR in both sexes. The above results suggest that the obesity indices and the serum lipid levels are closely related, i.e., the serum lipid levels increase with increasing obesity indices.