• Title/Summary/Keyword: TEN-T

Search Result 883, Processing Time 0.03 seconds

Screening of New Antibiotics Inhibiting Bacterial Methionyl-tRNA Synthetase (세균의 Methionyl-tRNA Synthetase를 저해하는 새로운 항생물질의 스크리닝)

  • 곽진환;조영준;송난규
    • YAKHAK HOEJI
    • /
    • v.45 no.3
    • /
    • pp.245-250
    • /
    • 2001
  • Aminoacyl tRNA synthetases of bacteria are known as potential targets for new anti-microbial agents. To isolate new inhibitors of bacterial methionyl-tRNA synthetases from natural sources, a new target-oriented screening system using whole cells which are over-expressing a target enzyme was developed. Approximately 8,000 culture broths of microorganisms from soils were tested by this screening system. Among them, ten culture broths was found to contain inhibitory activity against methionyl -tRNA synthetases of Escherichia coli. For the validation of the screening system, this new method was compared with in vitro enzymatic method. Seven out of 10 culture broths showed inhibitory activity against methionyl-tRNA synthetases of E. coli. This result showed that the new screening system was comparable to the enzyme assay. Thus we believe that our screening system as a new method can be applied for the screening of new antibiotics inhibiting bacterial methionyl-tRNA synthetases from natural products.

  • PDF

The Result of Radiation Therapy of Supraglottic Laryngeal Cancer for 15 rears (성문상부암 방사선치료 15년 성적)

  • Yoo, Seong-Yul;Koh, Kyoung-Hwan;Suh, Sung-Hee;Kim, Jin-Yong;Shim, Youn-Sang
    • Radiation Oncology Journal
    • /
    • v.2 no.2
    • /
    • pp.185-190
    • /
    • 1984
  • To assess the result of radiation therapy for fifteen fears experience, a total of 125 cases of pathologically proven supraglottic laryngeal cancer had been analyzed according to patient survival retrospectively. All the patients had been treated with radiation therapy in curative aim using Co-60 teletherapy machine. The results are as follows ; 1. According to AJCC staging, five year survival rate was $58.3\%$ in stage I, $44.4\%$ in II, $31.8\%$ in II, and $28.6\%$ in IV. 2. According to T-staging, five year survival rate was $57.1\%$ in T1, $40.5\%$ in T2, $34.0\%$ in T3, and $19.0\%$ in T4. 3. According to N staging, five year survival rate was $43.5\%$ in negative node group and $26.8\%$ in positive node group. 4. According to the histologic grade, the better in differentiation, the more in number of cases and the better in prognosis. 5. In summary, five year actuarial survival rate was $37.3\%$ and ten year surrival rate was $34.2\%$, and ten year survivors totalled 16 cases.

  • PDF

The Result of Radiation Therapy of Vocal Cord Cancer for 15 Years (성문암 방사선치료 15년 성적)

  • Yoo, Seong-Yul;Koh, Kyoung-Hwan;Suh, Sung-Hee;Kim, Chin-Yong;Shim, Youn-Sang
    • Radiation Oncology Journal
    • /
    • v.3 no.1
    • /
    • pp.13-18
    • /
    • 1985
  • To assess the result of radiation therapy for fifteen years experience, a total of 81 cases of pathologically proven vocal cord cancer had been analysed according to patient survival retrospectively. All the patients had been treated with radiation therapy using Co-60 teletherapy unit in curative aim. The results are as follows ; 1. According to AJCC staging, (ive year survival rate was $75.0\%$ in stage I, $73.1\%$ in stage II, $36.0\%$ in stage III, and $20.0\%$ in stage IV. 2. According to T-staging, five year survival rate was $75.0\%$ in T1, $73.1\%$ in T2, $24.3\%$ in T3, and $25.0\%$ in T4. 5, According to nodal status, five year survival rate was $59.4\%$ in negative node group and $14.2\%$ in positive group. 4. According to the histologic grade, the better in differentiation, the more in number of cases and the better in prognosis. 5. In summary, five year actuarial survival rate was $55.5\%$ and ten year survival rate was $49.8\%$ and ten year survivors totalled 12 cases.

  • PDF

A Clinical Study on the Anti-Stress Effects by Lyu's Soyosan(柳氏逍遙散) and Lyu`s Kwipithang(柳氏歸脾湯) (유씨소요산(柳氏逍遙散)과 유씨귀비탕(柳氏歸脾湯)의 항(抗)스트레스 효과(效果)에 관(關)한 임상적(臨床的) 연구(硏究))

  • Lee Sek-Jun;Lyu Heui-Yeong
    • Journal of Oriental Neuropsychiatry
    • /
    • v.5 no.1
    • /
    • pp.41-60
    • /
    • 1994
  • The objective of this paper is to verify clinical effects of Lyu's Soyosan(柳氏逍遙散) and Lyu's Kwipithang(柳氏歸脾湯). They were prescribed to the enperimental student group suffering from mental stress and annoyed by psychological instability. From the biochemical examination before and after medication, we measure the amount of hormonal variation in thyroid hormone(TSH, $T_4$) and adrenocortical hormone(ACTH, cortisol) The results are as follows. 1. The average of self-rating anxiety scale(SAS) in test group is $41.00\;{\pm}\;7.84$. This value is statistical significant and higher than one of normal person(age 20-39). The average of a global assesment of recent stress(GARS) scale is $28.62\;{\pm}9.00$. There is statistical correlation coefficient between SAS and GARS (p < 0.001). 2. Both Lyu's Soyosan(柳氏逍遙散) and Lyu.s Kwipithang (柳氏歸脾湯) groups show statistically significant reduction of total cholesterol and triglyceride level in serum lipid after ten day medication. 3. It is observed that Lyu's Soyisan(柳氏逍遙散) and Luy's Kwipithang (柳氏歸脾湯) groups have increasing tendency of TSH. The statistically significant reduction of $T_4$ was found in two groups after ten day medicaton. 4. It is observed that Lyu's Soyosan(柳氏逍遙散) and Lyu's kwipithang (柳氏歸脾湯) group have statistically significant reduction of serum cortisol level after ten day medication, Both groups have statistically significant reduction of plasma ACTH level after twenty day medication. From these results, it is verified that both Lyu's Soyosan(柳氏逍遙散) and Lyu's Kwipithang (柳氏歸脾湯) have anti-stress effects against psychological instability and mental stress. The Lyu's Soyosn(柳氏逍遙散) shows special effectiveness in depression of liver-energy(肝氣鬱結) and the Lyu's Kwipitang (柳氏歸脾湯) is also effective in deficiency heart-blood(心血不足).

  • PDF

A Study on the Fabrics in the Sumptuary Laws of Silla in Sam Guk Sa Ki(三國史記) (삼국사기의 복식연구 III -색복의 직물을 중심으로-)

  • 김진구
    • The Research Journal of the Costume Culture
    • /
    • v.6 no.2
    • /
    • pp.22-35
    • /
    • 1998
  • The objective of this study was to investigate and to identify and to classify the fabric names concerning costume in the sumptuary laws of Silla in Sam Guk Sa Ki(三國史記). The important findings of this study can be summarized as follows: Various names of fabrics concerning costume in the sumptuary laws of Silla were found to be classified into ten categories of fabrics. They were as follows: (1) kye( ), (2) Su(繡), (3) Kum(錦), (4) Ra(羅), (5) Reung(綾), (6) Sa(紗), (7) Si( ), (8) Kyun(絹), (9) Myun Ju(綿紬), (10) Po(布). Ra(羅) in ten categories was the most various. The numbering orders shown above were the orders of degree of valuability and preciousness of the fabrics in Silla. Namely, (1) Kye( ) was the most precious fabric, (2) Su(繡) was the second precious one, (3) Kum(錦) was the third precious one, and so on. It was found that the orders of the degree of preciousness of fabrics were a system for differentiating social class and rank, or sex of the people. It revealed the ordering system of the degree of the preciousness of fabrics of Silla was derived from T'ang dynasty. The system of Silla and T'ang system were almost the same each other. Materials used to manufacture fabrics were of mainly three kinds; e.g., wool, silk, and hemp. In these three kinds of materials silk was the most common stuff, and it was seen under the various names of the silks.

  • PDF

Effect of CAR and NPL on ROA: Empirical Study in Indonesia Banks

  • TANGNGISALU, Jannati;HASANUDDIN, Rusdiah;HALA, Yusriadi;NURLINA, Nurlina;SYAHRUL, Syahruni
    • The Journal of Asian Finance, Economics and Business
    • /
    • v.7 no.6
    • /
    • pp.9-18
    • /
    • 2020
  • This study seeks to analyze the effect of Non-Performing Loans and Capital Adequacy Ratio on Return on Assets on ten conventional banks listed on the Indonesia Stock Exchange (BEI-IDX). This study uses secondary panel data for 2015-2019 in the form of CAR and NPL values from ten conventional banks listed on the BEI-IDX during the 2020 observation period. The research approach is quantitative descriptive with data analysis methods, namely, linear regression. The testing phase of this study includes: transform value, F-test, T-test and hypothesis test with significancy level sig < 0.05. The results of this study reveal that Non-Performing Loans had a significant negative effect (t = -2,637) (0.011 <0.0) on Return on Assets, while Capital Adequacy Ratio has no significant effect on ROA (0.760 > 0.05). R2 value is 0.128 or 12.8%. It has a significant effect on variables, calling efforts by banks, governments, and authorities monetary of related institutions to maintain the stability of finance. The reduction of Non-Performing Loan impacts on assets and capital adequacy ratio, besides, the normal NPL will control the stability of finance. If a balance is created either in the form of values or amounts of the variables, the reduction in Non-Performing Loans will be controlled.

Estimation of Additive and Dominance Genetic Variances in Line Breeding Swine

  • Ishida, T.;Kuroki, T.;Harada, H.;Fukuhara, R.
    • Asian-Australasian Journal of Animal Sciences
    • /
    • v.14 no.1
    • /
    • pp.1-6
    • /
    • 2001
  • Additive and dominance genetic variances were estimated for purebred Landrace selected with line breeding from 1989 to 1995 at Miyazaki Livestock Experiment Station, Kawaminami Branch. Ten body measurements, two reproductive traits and fifteen carcass traits were analyzed with single-trait mixed model analysis. The estimates of narrow-sense heritabilities by additive model were in the range of 0.07 to 0.46 for body measurements, 0.05 to 0.14 for reproductive traits, and 0.05 to 0.68 for carcass traits. The additive model tended to slightly overestimate the narrow-sense heritabilities as compared to the additive and dominance model. The proportion of the dominance variance to total genetic variance ranged from 0.11 to 0.91 for body measurements, 0.00 to 0.65 for reproductive traits, and 0.00 to 0.86 for carcass traits. Large differences among traits were found in the ratio of dominance to total genetic variance. These results suggested that dominance effect would affect the expression of all ten body measurements, one reproductive trait, and nine carcass traits. It is justified to consider the dominance effects in genetic evaluation of the selected lines for those traits.

Selecting a Synthesizable RISC-V Processor Core for Low-cost Hardware Devices

  • Gookyi, Dennis Agyemanh Nana;Ryoo, Kwangki
    • Journal of Information Processing Systems
    • /
    • v.15 no.6
    • /
    • pp.1406-1421
    • /
    • 2019
  • The Internet-of-Things (IoT) has been deployed in almost every facet of our day to day activities. This is made possible because sensing and data collection devices have been given computing and communication capabilities. The devices implement System-on-Chips (SoCs) that incorporate a lot of functionalities, yet they are severely constrained in terms of memory capacitance, hardware area, and power consumption. With the increase in the functionalities of sensing devices, there is a need for low-cost synthesizable processors to handle control, interfacing, and error processing. The first step in selecting a synthesizable processor core for low-cost devices is to examine the hardware resource utilization to make sure that it fulfills the requirements of the device. This paper gives an analysis of the hardware resource usage of ten synthesizable processors that implement the Reduced Instruction Set Computer Five (RISC-V) Instruction Set Architecture (ISA). All the ten processors are synthesized using Vivado v2018.02. The maximum frequency, area, and power reports are extracted and a comparison is made to determine which processor is ideal for low-cost hardware devices.

Observation of the change of body temperature during the adaptation time in D.I.T.I (1) (적외선체열진단을 위한 외부온도 적응과정 중 체온변화 관찰 (1))

  • Park, Dae-Soon;Cho, Jung-Hoon;Jang, Jun-Bock;Lee, Kyung-Sub
    • Journal of Oriental Medical Thermology
    • /
    • v.3 no.1
    • /
    • pp.20-26
    • /
    • 2004
  • Purpose This study was performed to observe the change of body temperature during preparatory period. Method This study was carried out on 19 patients by D.I.T.I. The temperature was measured on Chondol(CV22), chonjung(CV17), the abdominal region and palm of Rt. and Lt. hand on every minutes for ten minutes. Result and Conclusion In male and female, until 6 minutes mean body temperature decreased but from 7 minutes it increased a little. Temperature in Chondol(CV22) and chonjung(CV17) also had similar tendency. However in the abdominal region temperature decreased and in palm of Rt. and Lt. hand it increased continously for ten minutes

  • PDF

Effect of Treadmill Training on Walking Velocity and Gait Endurance in patients with chronic hemiplegia (트레드밀 보행훈련이 만성편마비 환자의 보행 속도와 보행 지구력에 미치는 영향)

  • Kim Sang-Yub
    • The Journal of Korean Physical Therapy
    • /
    • v.16 no.2
    • /
    • pp.44-53
    • /
    • 2004
  • Treadmill training is a new promising therapy in gait rehabilitation of patients with hemiplegia. The purpose of this study was to identify the effect of treadmill training on walking speed and gait endurance in patients with chronic hemiplegia. The subject of this includes twenty patients, who had suffered from chronic hemiplegia and were in the K rehabilitation center; each ten patients were randomly assigned to experimental or control group. Among twenty patients, one group of ten for experiment was treated with progressive speed increase treadmill ambulation traing besides conventional physical therapy(SITAT) while the rest ten for the controlled group was treated with conventional physical therapy(CPT) only, for 8 weeks alike. Before and after the foregoing 8 weeks training, walking velocity and gait endurance were measured to both groups. The data were analyzed by paired t-test. The results of this study are as follows; The SITAT and CPT showed the significant difference in walking velocity and gait endurance. As compared the rehabilitation of dependent varibles between the SITAT and CPT, SITAT showed the significant difference in walking velocity and gait endurance. The outcome suggest that patient with chronic hemiplegia can improve their walking velocity and gait endurance throught treadmill training.

  • PDF