• Journal of Korean Ophthalmic Optics Society
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• v.13 no.1
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• pp.15-20
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• 2008

Purpose: To study on the confidence of dry eye diagnosis methods which need to prescribe contact lens. Methods: Non-invasive tear film break-up time (NIBUT) and tear film break-up time (TBUT) were measured in forty healthy subjects in their 20s, and then the subjects were classified into normal eye and dry eye. The results of McMonnies questionnaire, tear prism height measurement, Hardtack test, blink rate measurement and Schirmer test were compared with the results of NIBUT and TBUT. Results: The results of NIBUT and TBUT were as follows; 20 subjects had normal eyes, 10 subjects had dry eyes in both NIBUT and TBUT, and 10 subjects showed different results. In McMonnies questionnaire, the score of normal eye group averaged 8.2 and that of dry eye group averaged 18.5, which showed statistically significant difference. Furthermore, 100% of normal eye group classified by the results of NIBUT and TBUT corresponded with the result of McMonnies questionnaire and 90% of dry eye group showed the correspondence. Tear prism height of normal eye group averaged 0.32 mm and that of dry eye group averaged 0.23 mm, which were significantly different. Hardtack test, blink rate measurement and Schirmer test without local anesthesia showed no statistically significant difference between normal eye group and dry eye group. Conclusions: On dry eye diagnosis methods, the results of McMonnies questionnaire and tear prism height measurement had close correlation with the results of NIBUT and TBUT.

• Journal of the Korea Academia-Industrial cooperation Society
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• v.14 no.6
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• pp.2839-2843
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• 2013

In this study, the relation between the corneal refractive power and the tear break-up time(TBUT) was analyzed. The results can be effectively used in eye clinics and served as the reference on wearing the contact lenses. We had measured the radius of the corneal of university students who are in the range of 21 to 27 year-old and who don't have eye disease. The corneal refractive power was calculated by using the radius of the corneal. And TBUT is the time when the mire image is distorted first time. The relation between the corneal refractive power and TBUT in right eye was a linear as 'y=37.921-0.610x', in which the larger the refractive power of the cornea is, the shorter TBUT is(negative relationship; r=-0.462, p=0.010). The relation in left eye was also a negatively linear as 'y=41.894-0.695x'(r=-0.509, p=0.004). Consequently, in both eyes the corneal refractive power and TBUT have a negative correlation when myopia is a high. It is possible to predict TBUT, which is necessary in deciding on wear of contact lenses, by measuring the corneal radius of subjects.

• Journal of Korean Ophthalmic Optics Society
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• v.13 no.2
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• pp.1-7
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• 2008

Purpose: This study was performed to evaluate the changes of lens morphology and tear stability during wearing soft contact lenses (SCLs) which were kept in drying condition like dry eye or became to be dried due to heedless care. Method: SCLs having different water content, thickness or material were rehydrated after being dehydrated artificially 2 or 4 times, and estimated their diameter and radius. Furthermore, the changes of tear film break-up time (TBUT) during SCL wearing were also measured. Result: Due to the dryness, the diameter of both 70% water content SCL and 59% water content SCL decreased, but the decrement was larger in 59% water content SCL. The more 59% water content SCL was dehydrated, the more its radius changed. However, the radius of 70% water content SCL did not change by 2 times dehydration and increased greatly by 4 times dehydration. The reduction of diameter of -1.00 D SCL was greater than that of -9.00 D SCL. Moreover, the radius of -1.00 D SCL increased depending on the frequency of dehydration but that of -9.00 D SCL did not changed. The diameter and radius changes of lotrafilcon B, silicone hydrogel lens, were less than those of hilafilcon B, copolymer of HEMA and N-vinyl pyrrolidone. TBUT during wearing SCLs decreased by wearing dehydrated SCLs. Conclusion: The diameter and radius of dehydrated SCLs as well as TBUT during wearing them were changed in spite of rehydration, which would be the important cause of uncomfortable feeling when people wore dehydrated SCL. The changes of SCL morphology and TBUT differed according to the water content, lens thickness and material.

• Journal of Korean Ophthalmic Optics Society
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• v.6 no.2
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• pp.161-164
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• 2001

The purpose of our study was stability of tear film for Korean. In the 1970s, the major problem for the contact lens practitioner was the management of contact lens parameters. In the 1980s, oxygen permeability was the main problem in contact lens practice: now it is dry eyes. To appropriately fit the patient with contact lenses it is imperative to know in advance if the patient has a marginal dry eye. Based on the initial diagnosis appropriate care can be taken to minimize problems with the result that the patient can successfully wear contact lenses. A well known test for dry eyes is Schirmer test which has shown to be useful for diagnosing Sjogren syndrome. Biomicroscopy can often unmask numerous problems. The classical test for marginal dry eye is measuring the tear break up time(TBUT). A dry eye problem with contact lenses is often caused by the lid. If an incomplete blink is responsible for the dry eye it is possible to change the situation by blinking exercises. The result of these test, mean value of age was 22.8, mean value of blink rate was 19 times/min, mean value of Schirmer test was 25 mm/5 min, mean value of TBUT was 7.1 sec.

• Journal of Korean Ophthalmic Optics Society
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• v.9 no.2
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• pp.301-312
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• 2004

This study was performed to compare the relationship between contact lens wearer and dry-eye patient. In this study, TBUT, SIT, TTT, Rose bengal staining and McMonnies dry eye symptom questionnaire were performed as a baseline. With the base data, the subjects were classified to 3 groups : 3S patients who have dry eye signs and symptoms, 38 patients who are wearing soft contact tenses, 35 subjects who have health eyes and never worn on a contact lenses as control subjects. Contact lens wearers were divided into 3 groups according to the duration of contact lens wear. There were no significant differences in TBUT, STT, TTT, Rose-bengal staining and McMonnies dry eye symptom questionnaire result between contact lens wearer group and dry eye patients group. We suggest that there are similarities in tear function tests between the dry-eye patient and the contact lens wearer.

• Journal of Korean Ophthalmic Optics Society
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• v.20 no.4
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• pp.519-526
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• 2015

Purpose: To evaluate the changes of OSI value according to tear-film instability measured serially by OQAS(Optical Quality Analysis System, Visiometrics, Spain) every seconds. The presented study analyzed the relationship of the OQAS parameter with the results of the tear-film break-up time, Schirmer test, and the McMonies score. Methods: 147 eyes of 82 subjects were randomly selected from university students (age: $21.51{\pm}3.97$, male 45, female 37). Subjects were measured tear-film break-up time, Schirmer test, McMonies score and once every second for 15 seconds after blinking by continuous measurements from OQAS system. Results: The normal eye groups presented OSI values of $2.13{\pm}1.16$ while the dry eye groups had OSI values of $3.76{\pm}1.42$. Therefore, a significant difference between the normal eye group and dry eye group was discovered (p<0.05). In addition, the OSI value of all subjects increased over time. The OSI value, which was measured every second after blinking occurred, significantly increased between 6 seconds and 7 seconds after the start of the measurement (p<0.05). OSI cut off of 30% (sec.) showed a greater correlation; TBUT (r = 0.855, p = 0.000), McMonies test (r = -0.351, p = 0.003), Schirmer (r = 0.316, p = 0.012). Conclusions: Continuous measurement of OQAS showed a high correlation with the value of the existing dry eye tests. Therefore, Analysis of OSI values by utilization of OQAS could be useful in objectively evaluation of tear film in patients.

• Journal of The Korean Ophthalmological Society
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• v.59 no.12
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• pp.1103-1107
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• 2018

Purpose: To evaluate the clinical effect of intense regulated pulse light (IRPL) and changes in tear film thickness in dry eye patients. Methods: A retrospective study was conducted on 25 patients with Meibomian gland dysfunction who had subjective dry eye discomfort and whose tear film break-up time (TBUT) was < 10 seconds. All patients were treated with IRPL three times on days 1, 15, and 45. TBUT, Schirmer 1 test results, cornea staining score with fluorescein, ocular surface disease index (OSDI), and lipid layer thickness were measured and compared before and after the procedure. Results: TBUT was significantly increased from $3.7{\pm}1.2s$ to $4.4{\pm}2.1s$ after IRPL (p = 0.03). Schirmer 1 test and cornea staining scores changed significantly (p < 0.01 and p = 0.01, respectively). OSDI also showed a statistically significant improvement from $39.5{\pm}17.5points$ to $30.4{\pm}18.7points$ (p = 0.01). However, no significant difference in lipid layer thickness was observed (p = 0.49). Conclusions: IRPL is an effective treatment modality to improve TBUT, Schirmer 1 test scores, cornea staining scores, and subjective dry eye symptoms.

• Journal of Digital Convergence
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• v.10 no.11
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• pp.535-540
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• 2012

This study is to research the differences of tear film for young people in of a day in a restricted indoor space. The subjects are 58 eyes volunteers for twice preliminary inspection and tear test of a day. 58 healthy individuals with no eye disease, no body disease, orthophoria, corrective visual acuity more than 0.8, binocular spherical equivalence difference over 0.50 diopter, the flattest corneal curvature in horizontal meridian and the steepest corneal curvature in vertical meridian were tested. The uncorrective visual acuity, refractive error, corneal curvature, schirmer test and tear break up test were performed in the morning and afternoon. Schirmer test were $16.0{\pm}7.0mm$ in the morning and $14.1{\pm}7.1mm$ in the afternoon. TBUT were $11.3{\pm}0.6$ sec in the morning and $12.1{\pm}0.9$ sec in the afternoon. They have no significant differences.

• Journal of Korean Ophthalmic Optics Society
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• v.20 no.2
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• pp.247-253
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• 2015

Purpose: The purpose of this study was to compare and analyze the ocular surface and the palpebral conjunctiva of categorized subjects, which were divided into normal eye group and dry eye group, by using a thermal camera. Methods: Subjects were 144 eyes of 72 normal university students, who didn't have any corneal disease, abnormal lacrimal ducts, medical records regarding ocular surgeries, or experience of using contact lens. Subjects were divided into two groups, which were normal eye group and dry eye group, based on the results of TBUT, Schirmer I test, and McMonnies test. After categorizing the subjects, the temperature of the subjects' ocular surface and the palpebral conjunctiva were measured and analyzed by using a thermal camera (Cox CX series, Answer co., Korea). Results: In the normal eye group's Central Ar.1, Nasal Ar.2, Temporal Ar.3, Superior Ar.4, Inferior Ar.5, the measured amount of temperature change on each area was $-0.13{\pm}0.08$, $-0.14{\pm}0.08$, $-0.12{\pm}0.08$, $-0.14{\pm}0.08$, $-0.10{\pm}0.09(^{\circ}C/sec)$. The dry eye group's results were $-0.17{\pm}0.08$, $-0.16{\pm}0.07$, $-0.16{\pm}0.08$, $-0.17{\pm}0.09$, $-0.15{\pm}0.08(^{\circ}C/sec)$. When compared with the normal eye group, the values of Ar.1, Ar.3, Ar.5 were significantly different in the dry eye group(p<0.05). The amount of temperature change, which was observed on the palpebral conjunctiva(Ar.1:central, Ar.2: nasal, Ar.3: temporal) of the normal eyes, measured by thermography, was $34.36{\pm}1.12$, $34.17{\pm}1.10$, $34.07{\pm}1.12^{\circ}C$ on each area. Same values taken from the dry eye group was $33.55{\pm}0.94$, $33.43{\pm}0.97$, $33.51{\pm}1.06^{\circ}C$ on each area. The values of Ar.1, taken from the dry eye group, had a significant difference, compared to the values of the normal eye group(p=0.05). Conclusion: The temperature of the ocular surface decreased faster on the dry eyes, compared to the normal eyes. The temperature measured on the palpebral conjunctiva of the dry eyes were also lower than the normal eyes. The temperature changes on the ocular surface, observed with a thermal camera, were objective values to assess the stability of tear films, and might provide useful data for studies related to dry eye syndrome.

• Journal of Convergence Society for SMB
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• v.6 no.4
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• pp.85-91
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• 2016

This study is to research the tear film stability for 48 eyes, agreed the purpose of study, didn't have no contact lens wearing and were tested all two times in a day. Their visual acuity was more than 0.8, corrective visual acuity more than 0.8, the fattest K-reading, apical corneal radius, was in 7.40~8.40mm, corneal astigment was less than 1.00D and orthophoria. The tests, tear scope test, tear film break up time test(TBUT) and schirmer test order, were performed their functions before and after their working at interval of 6 hours over. The tearscope test results was no difference, TBUT was no difference, although 1.2 seconds more in the afternoon, shcirmer test was decreased 2.0mm in the afternoon.