• 센서학회지
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• 제26권6호
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• pp.432-437
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• 2017

As 4.0 industry has been developed, research on a self-driving car technology and related parts of an automobile has been highly investigated recently. Particularly, a TAS(Torque Angle Sensor) module on steering wheel system has been considered as a key technology because of its precise angle, torque detection and high speed signal processing. The environmental assessment is generally required on the TAS module to examine high resolution of angle/torque detection. In the case of existing TAS module, angle detection errors has been occurred by back-lash on main and sub gear in addition to complicated structure caused by gears. In this paper, a structure of the TAS module, which minimizes the numbers of components and angle detection errors on the module compared with the existing TAS module, for vehicle steering system based on a Multi-track Encoder has been proposed. Also, angle detection signal processing board, and key technology of the TAS module were fabricated and evaluated. As a result of the experiments, we confirmed an excellent performance of the fabricated signal processing board for angle detection and an applicability of the fabricated angle detection board on the TAS module of vehicles by the environmental assessment an automobile standard.

• Asian Pacific Journal of Cancer Prevention
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• 제13권5호
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• pp.2009-2014
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• 2012

Objective: Taspine, isolated from Radix et Rhizoma Leonticis has demosntrated potential proctiective effects against cancer. Tas13D, a novel taspine derivative synthetized by structure-based drug design, have been shown to possess interesting biological and pharmacological activities. The current study was designed to evaluate its antiproliferative activity and underlying mechanisms. Methods: Antiproliferative activity of tas13D was evaluated by xenograft in athymic mice in vivo, and by 3-(4, 5-dimethylthiazol-2-yl)-2, 5-diphenyltetrazolium bromide (MTT) and cell migration assays with human liver cancer (SMMC-7721) cell lines in vitro. Docking between tas13D and VEGFR and EGFR was studied by with a Sybyl/Surflex module. VEGF and EGF and their receptor expression was determined by ELISA and real-time PCR methods, respectively. Results: Our present study showed that tas13D inhibited SMMC-7721 xenograft tumor growth, bound tightly with the active site of kinase domains of EGFR and VEGFR, and reduced SMMC-7721 cell proliferation (IC=34.7 ${\mu}mol/L$) and migration compared to negative controls. VEGF and EGF mRNAs were significantly reduced by tas13D treatment in a dose-dependent manner, along with VEGF and EGF production. Conclusion: The obtained results suggest that tas13D inhibits tumor growth and cell proliferation by inhibiting cell migration, downregulating mRNA expression of VEGF and EGF, and decreasing angiogenic factor production. Tas13D deserves further consideration as a chemotherapeutic agent.

• 전자공학회논문지A
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• 제31A권6호
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• pp.88-97
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• 1994

We describe the design, fabrication, and performance of the optical fiber-photodiode 1$\times$12 arry module using mesa-type InS10.53T GaS10.47TAS/INP 1$\times$12 PIN photodiode array. We fabricated the PIN PD array for high-speed optical fiber parallel data link optimizing quantum efficiency, operating speed sensitivity from the PIN-FET structure, and electrical AC crosstalk. For each element of the array, the diameter of the photodetective area is 80 $\mu$m, the diameter of the p-metal pad is 90 $\mu$m, and the photodiode seperation is 250 $\mu$m to use Si v-groove. Ground conductor line is placed around diodes and p-metal pads are formed in zigzag to reduce Ac capacitance coupling between array elements. The dark current (IS1dT) is I nA and the capacitance(CS1pDT) is 0.9 pF at -5 V. No signifcant variations of IS1dT and CPD from element to element in the array were observed. We calulated the coupling efficiency for 10/125 SMF and 50/125 GI MMF, and measured the responsivity of the PD array at the wavelength is 1.55 $\mu$ m. Responsivities are 0.93 A/W for SMF and 0.96 A/W for MMF. The optical fiber-PD array module is useful in numerous high speed digital and analog photonic system applications.

• 대한기계학회논문집B
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• 제27권10호
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• pp.1377-1384
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• 2003

An analysis has been performed for active thermal control of the KOMPSAT monopropellant rocket engine assembly, i.e., dual thruster module(DTM). The main efforts of this work have been directed at determining proper heater sizes for propellant valves and catalyst beds necessary to maintain their temperatures within specified temperature ranges under KOMPSAT environment and operational conditions. The TAS incorporated with TRASYS thermal radiation analyzer was used to establish a complete heat transfer model which allows to predict the DTM temperature as a function of time. The thermal analysis has been performed in transient mode to verify the appropriate power for catalyst bed heaters necessary to increase catalyst bed temperature to the required value within a specified period of time. Similar analysis has been executed to validate the heater power for the thermostatically controlled primary and redundant heater circuits used to prevent hydrazine freezing, i.e., single fault. Moreover the effect of the radiative property of thermal control coating of heat shield was examined. Thruster firing condition was also simulated for the heat soakback condition. As a consequence, all thermal analysis results for DTM satisfactorily met the thermal requirements for the KOMPSAT DTM under the worst case average voltage, i.e. 25 volt.

• 대한기계학회논문집A
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• 제36권5호
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• pp.475-479
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• 2012

본 논문은 고차가지구조 폴리머인 AEO3000 를 이용한 UV 광경화 성형 공정을 제안하고자 한다. 이는 기존의 바이오칩 제작에 사용되는 PDMS 보다 경도가 높아 금속 전극 형성이 용이하고 제작 공정이 빠르다는 장점을 갖는다. AEO3000 을 이용하여 본 연구에서는 4 개의 소자를 전기적 유체적으로 연결할 수 있는 전기유체 통합벤치를 제작하고 미소유체 혼합소자와 세포분리소자를 연결, 본 소재와 공정이 바이오칩에 적용될 수 있음을 검증하였다. 전기 유체적 특성 분석 결과 전기적 접촉 저항은 $0.75{\pm}0.44{\Omega}$으로 충분히 작은 값을 보였으며, 유체 접속의 압력 저하는 8.3kPa로 기존의 튜브 연결 방법 대비 39.3% 개선된 값을 보였다. 통합벤치에 접속된 소자에 활성 및 비활성 효모를 주입하여 순차적인 혼합 및 재분리를 성공적으로 구현함으로써 본 소자에 적용된 AEO3000 및 UV 광경화 공정이 생체시료의 처리에 적용될 수 있음을 실험적으로 검증하였다. 이는 바이오 의료 분야에 적용 가능한 생체 친화적 소재의 고속 생산에 응용될 수 있다.