• Microbiology and Biotechnology Letters
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• v.17 no.4
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• pp.343-348
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• 1989

Production of shikonin derivatives by Lithospermum erythrorhizon cells by using polyurethane foam was invesliigated. Shikonin derivatives were effectively adsorbed mostly by phase distribution to polyurethane matrices and their production increased significantly compared to the suspension culture. The enhanced production of shikonin was probably due to more facilitated cell to cell con-tact and lowered intracellular shikonin concentration, both of which are known to be favorable for plant secondary metabolite production. In order to improve the process productivity, tell culture was conducted under various culture conditions: Of them, Schenk and Hildebrandt medium containing indole-3-acetic acid (1.75mg/ι) and kinetin (0.1mg/ι) was considered most appropriate for shikonin production. Production of shikonin increased about 4.5 times in the Schenk and Hildebrandt medium containing indole-3-acetic acid (1.15mg/ι) and kinetin (0.1mg/ι) when compared to the same medium containing p-chlorophenoxyacetic acid (2.0mg/ι) and kinetin (0.1mg/ι). When poly-urethane was used as the support material, a single-stage system was more preferred to the conventional two-stage culture system in terms of shikonin productivity.

• Journal of the Korea Society for Simulation
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• v.17 no.2
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• pp.63-74
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• 2008

The design of best efficient production process is common requirements of the production strategy department and the process planning department to maximize the revenue and accomplish target production volumes in the production periods. And they use several general methods for that-line-balancing, removing of the bottle-neck process, facility ramp-up, increasing of the worker's utilization, etc. But, those methods have depended on analytic, static and arithmetic calculations, yet. So, irregular work-waiting time causing the delay time isn't include in extracting production capacity, especially in the line production process. The work-waiting time is changed irregularly along the variation of each machine and very important for calculate real product lead-time and forecasting target production volumes. At this thesis, i'm going to mention the importance of the delay time of conveyor system which can be extracted by discrete-event simulation. And suggest it as a new main variable that must be considered at designing new production system. Then experimented and tested that's effects in the H-company case, conveyor based line production process.

• 한국정보디스플레이학회:학술대회논문집
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• 2008.10a
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• pp.873-878
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• 2008

Doosan Mecatec has developed alignment system for Organic Light-Emitting Diode (OLED) display production using large size substrate. In the present article, The alignment system between the substrate and the mask, which is a core technology for producing the OLED product using the fourth-generation substrate with $730{\times}920mm^2$ or more, will be described by dividing into a substrate loader, a magnet unit, a CCD camera, etc. The substrate loader is optimized through the simulation where the central portion of the substrate droops by about 1.5mm by clamping each of a long side (920mm direction) and a short side (730mm direction) thereof by 6 point and 4 point. A magnet unit using a sheet type of rubber magnet is constituted and a CCD camera model with the specifications capable of minimizing the errors between a clear image and the same image is selected. The system to which an upward evaporation technique of small molecular organic materials will be applied has been developed so that repeatability and position accuracy becomes ${\pm}1{\mu}m$ or less using an UVW type of stage. Also, the vision accuracy of the CCD camera becomes ${\pm}1{\mu}m$ or less and the align process TACT becomes 30sec. or less so that the final alignment accuracy between the substrate and the mask becomes ${\pm}3{\mu}m$ or less. In order to meet an extra-large glass substrate, an evaporation system using an extra-large AMOLED substrate has been developing through a vertical type of an alignment system.

• Tunnel and Underground Space
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• v.30 no.6
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• pp.519-539
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• 2020

We reviewed numerical approaches to assess a hydraulic properties of excavation-disturbed zone (EDZ)created in argillaceous sedimentary rocks. It has been reported that fractures in the sedimentary rocks containing expansive clays are gradually closing due to swelling and their permeabilities are evolving to the level of in-tact rock, which is known as a self-healing or self-sealing process. The numerical approaches introduced here are capable of simulating spatio-temporal variation of EDZ permeability during long-term operation of a repository by including the self-healing characteristics of fractures, which wa observed in laboratory as well as in-situ experiments, The applicability of the numerical approaches was verified from the comparison to in-situ measurements of EDZ permeability at underground research laboratories.

• Journal of Korea Foundry Society
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• v.43 no.4
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• pp.187-193
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• 2023

Shell core making is an excellent process in terms of formability and desanding, but when the molten aluminum comes into con- tact with the shell core, gas generation by pyrolysis of the resin is inevitable. In addition, when the ventilation is inadequate, pores will remain inside the casting, which can directly lead to defects of the casting. While studies on the gas generation behavior of shell core making have been reported, the modeling of gas generation has not been extensively investigated. We will develop a gas evolution analysis method that considers the relationship between temperature and gas quantity for the core to be developed. We then use the developed method to analyze the flow and solidification behavior of metal molten metal during core mold design and low-pressure casting of cylinder head products, and predict the occurrence of casting defects to derive a casting method that min- imizes the occurrence of defects.