• 한국의류학회지
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• 제47권2호
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• pp.337-352
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• 2023

This study develops a t-shirt design that align bones and balance muscles in order to maintain proper posture using the basic concepts of symmetry. First, theoretical and 3D design studies, existing literature on proper and improper posture, and the basic concepts of symmetry are studied to create the design. Next, the 3D design process applies bilateral, rotational, and scaling symmetries to design the inner lines from the basic application of symmetry. A two-stage design process is used, whereby the strain map and pressure points are analyzed using the CLO virtual clothing software, and the most effective design is determined through virtual testing. The results show that the Y+)( and X+― design, which combines the position and type of inner lines, is the most effective for posture correction and maintenance. Overall, this study helps create a theoretical and practical basis for exploring and understanding basic lines appropriate for the human body, and subsequently, for developing various products that maintain posture more accurately and precisely.

• Molecules and Cells
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• 제37권8호
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• pp.605-612
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• 2014

The p73 gene contains an extrinsic P1 promoter and an intrinsic P2 promoter, controlling the transcription of the pro-apoptotic TAp73 isoform and the anti-apoptotic ${\Delta}Np73$ isoform, respectively. The DNA methylation status of both promoters act equally in the epigenetic transcriptional regulation of their relevant isoforms. The aim of this study was to analyze the different effects of these p73 isoforms in 5-aza-2'-deoxycytidine (5-aza-dC)-induced apoptosis in breast cancer cells. We investigated the effects of the DNA demethylation agent, 5-aza-dC, on the T-47D breast cancer cell line, and evaluated the methylation status of the p73 promoters and expression of TAp73 and ${\Delta}Np73$. Furthermore, we assessed the expression of p53 and p73 isoforms in 5-aza-dC-treated T-47D cells and p53 knockout cells. 5-aza-dC induced significant anti-tumor effects in T-47D cells, including inhibition of cell viability, G1 phase arrest and apoptosis. This was associated with p73 promoter demethylation and a concomitant increase in TAp73 mRNA and protein expression. In contrast, the methylation status of promoter P2 was not associated with ${\Delta}Np73$ mRNA or protein levels. Furthermore, demethylation of P2 failed to inhibit the expression of ${\Delta}Np73$ with 5-aza-dC in the p53 knockdown cell model. Our study suggests that demethylation of the P1 and P2 promoters has opposite effects on the expression of p73 isoforms, namely up-regulation of TAp73 and down-regulation of ${\Delta}Np73$. We also demonstrate that p53 likely contributes to 5-aza-dC-induced ${\Delta}Np73$ transcriptional inactivation in breast cancer cells.

• 대한수학회보
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• 제47권5호
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• pp.915-932
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• 2010

The goal of this paper is to study extension problems of several continuities in computer topology. To be specific, for a set $X\;{\subset}\;Z^n$ take a subspace (X, $T_n^X$) induced from the Khalimsky nD space ($Z^n$, $T^n$). Considering (X, $T_n^X$) with one of the k-adjacency relations of $Z^n$, we call it a computer topological space (or a space if not confused) denoted by $X_{n,k}$. In addition, we introduce several kinds of k-retracts of $X_{n,k}$, investigate their properties related to several continuities and homeomorphisms in computer topology and study extension problems of these continuities in relation with these k-retracts.

• Imaging Science in Dentistry
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• 제54권3호
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• pp.276-282
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• 2024

Purpose: This study aimed to assess the performance of 2-dimensional (2D) imaging with microscopy coils in delineating teeth and periodontal tissues compared with conventional 3-dimensional(3D) imaging on a 3 T magnetic resonance imaging (MRI) unit. Materials and Methods: Twelve healthy participants (4 men and 8 women; mean age: 25.6 years; range: 20-52 years) with no dental symptoms were included. The left mandibular first molars and surrounding periodontal tissues were examined using the following 2 sequences: 2D proton density-weighted (PDw) images and 3D enhanced T1 high-resolution isotropic volume excitation (eTHRIVE) images. Two-dimensional MRI images were taken using a 3 T MRI unit and a 47 mm microscopy coil, while 3D MRI imaging used a 3 T MRI unit and head-neck coil. Oral radiologists assessed dental and periodontal structures using a 4-point Likert scale. Inter- and intra-observer agreement was determined using the weighted kappa coefficient. The Wilcoxon signed-rank test was used to compare 2D-PDw and 3D-eTHRIVE images. Results: Qualitative analysis showed significantly better visualization scores for 2D-PDw imaging than for 3D-eTHRIVE imaging (Wilcoxon signed-rank test). 2D-PDw images provided improved visibility of the tooth, root dental pulp, periodontal ligament, lamina dura, coronal dental pulp, gingiva, and nutrient tract. Inter-observer reliability ranged from moderate agreement to almost perfect agreement, and intra-observer agreement was in a similar range. Conclusion: Two-dimensional-PDw images acquired using a 3 T MRI unit and microscopy coil effectively visualized nearly all aspects of teeth and periodontal tissues.

• 한국전산유체공학회:학술대회논문집
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• 한국전산유체공학회 2008년도 12th Asian Congress of Fluid Mechanics
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• pp.47.1-47.1
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• 2008

• 생명과학회지
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• 제20권5호
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• pp.805-810
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• 2010

본 연구의 목적은 다시마투여와 운동트레이닝이 흰쥐의 혈당과 지질성분에 미치는 영향을 규명하기 위함이다. 4주령의 수켯 쥐 27마리를 대조군(C, n=9), 다시마투여군(D, n=9)과 다시마투여와 운동트레이닝군(D+T, n=9)으로 나누었다. 운동트레이닝은 6주간 1주일에 5회, 30분간 트레드밀위에서 실시하였다. 혈당(C:$175.9{\pm}47.5$, D:$173.9{\pm}34.0$, D+T:$165.0{\pm}38.0\;mg/dl$)과 중성지질(C:$251.1{\pm}91.8$, D:$215.0{\pm}90.0$, D+T:$200.0{\pm}89.3$)의 집단 간의 차이는 존재하지 않았다. 콜레스테롤수치는 D+T군($81.8{\pm}11.2$)이 다른 두집단에 비해 낮았다(C:$103.0{\pm}13.5$, D:$102.1{\pm}14.5$). HDL-C의 수치는 D+T군($40.9{\pm}9.7$)이 상대적으로 다른 두집단에 비해 높았다(C:$32.6{\pm}3.8$, D:$31.7{\pm}7.3$). D군($98.0{\pm}41.0$)의 LDL-C수치는 통계적으로 C군($114.5{\pm}41.8$)보다 낮았으며, D+T군($91.2{\pm}41.7$)보다 높았다. 결론적으로, 다시마투여와 운동트레이닝은 혈중지질에 긍정적인 효과를 가져왔다.

• 한국물환경학회지
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• 제37권1호
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• pp.47-54
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• 2021

Aerobic granular sludge (AGS) can be classified as a type of self-immobilized microbial aggregates measuring more than 0.2 mm. It offers the option to simultaneously remove COD, N, and P that occur in different zones inside a granule. Also, AGS is characterized by high precipitability, treatability with high organic loading, and high tolerance to low temperature. In this study, a sequencing batch reactor inoculated with AGS (AGS-SBR) is a new advanced wastewater treatment process that was proven to grow AGS with integrated nutrient removal and low C/N ratio. A pilot plant, AGS-SBR with a capacity of 225 ㎥/d was installed at an S sewage treatment plant in Gyeonggi-do. The results of the operation showed that the water quality of the effluent indicated that the value of BOD5 was 1.5 mg/L, CODMn was 11.4 mg/L, SS was 6.2 mg/L, T-N was 13.2 mg/L, and T-P was 0.197 mg/L, and all of these values reliably satisfied an effluent standard (I Area). In winter, the T-N treatment efficiency at a lower temperature of less than 11℃ also showed reliability to meet the effluent standard of the I Area (20 mg/L or less). Analysis of microbial community in AGS showed a higher preponderance of beneficial microorganisms involved in denitrification and phosphorus accumulation compared with activated sludge. The power consumption and sludge disposal cost were reduced by 34.7% and 54.9%, respectively, compared to the domestic SBR type sewage treatment plant with a processing capacity of 1,000 ㎥/d or less.

• Journal of Animal Science and Technology
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• 제47권5호
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• pp.769-782
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• 2005

Holstein 거세송아지 24두를 대상으로 육성 및 비육전기의 조사료 급여형태에 따라 3개 처리(T1: 농후사료+볏짚, T2: 농후사료+목건초, T3: 맥주박 TMR)를 두어 6개월령부터 23개월령까지 18개월간 사양시험 후 도체조사를 실시한 결과, 처리별 출하체중 및 일당증체량은 각각 751-802 kg(평균 782.3 kg) 및 1.064-1.159 kg(평균 1.122 kg)으로 모두 T2 > T3 > T1 순으로 높았고, T2의 일당증체량이 T1에 비해 8.9%가 개선되었다. 도체율, 등지방두께 및 등심단면적은 각각 60.6-60.9 %, 6.50-7.13mm 및 82.9-84.1cm2 이었고, 근내지방도 및 육색은 각각 3.1-3.3 및 4.0-4.1 이었으며, 쇠고기의 전단력 및 보수력은 각각 4.6-4.7 및 50.7-50.9로 이들 모두는 처리간에 유의차는 없었으나, 소득은 두당 882.8-991.7천원으로 T2 및 T3가 T1 보다 12-7% 더 높았다.이상과 같은 결과들을 종합해 볼 때 Holstein 거세우를 23개월령까지 비육할 경우, 근내지방도가 높은 쇠고기 생산이 가능하며, 육성 및 비육전기에 목건초나 맥주박위주의 TMR을 급여하면 볏짚보다 출하체중을 높여 소득을 향상시킬 것으로 판단된다.

• Journal of Animal Science and Technology
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• 제47권1호
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• pp.1-10
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• 2005

Intramuscular fat content(lMF) is considered as one of major economic traits in the pig breeding and industry. In general, high IMF results in better meat quality. Several approaches to detect quantitative trait 10ci( QTL) for IMF indicated a strong possibility of the existence of a QTL related to IMF between the microsatellite marker SW71 and SW1881 on SSC6q. Porcine FABP3 has been considered as a candidate gene affecting IMF due to its physiological roles and position on the pig genome. Two novel mutations, g.-114T> C and g.-158T>G were detected by duplicate sequencing of the porcine FABP3 promoter region. These two mutations were identified as absolute linkage disequilibrium. The g.-158T> G mutation was used for investigating relationships with growth and fat deposition traits. The GG genotype of the g.-158T> G polymorphism showed highly negative effects(P< 0.01) on body weights at 3 and 12 weeks of age, and a positive effect(P< 0.05) on IMF. However, backfat thickness(BF) and carcass fat(CF) content were not significantly associated with the genotype. The result indicates that the novel mutations, identified in this study, could be utilized as possible genetic markers to improve IMF, independent with BF.

• 한국ITS학회 논문지
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• 제11권1호
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• pp.42-52
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• 2012

본 논문에서는 UWB (Ultra Wide Band) high 대역 (중심 주파수 : 9.5 GHz, -10 dB 대역폭 : 600 MHz, 6.4 %)의 차량 측후방 레이더 센서용 도파관 안테나를 설계 및 제작하였다. 안테나는 대역폭이 넓고 구조가 간단한 프로브 급전 구형도파관을 이용하였다. 본 연구의 차량 레이더 시스템에 있어서 송수신 안테나의 큰 격리도 특성을 얻는 것이 설계의 중요한 변수이다. 따라서 두 도파관 안테나를 E-면과 H-면 배열하였을 시 격리도 특성을 시뮬레이션 하였다. 그 결과 도파관 안테나의 $TE_{10}$ 모드에 의하여 E-면 배열 보다 H-면 배열의 격리도 특성이 우수한 것을 확인하였다. 따라서 H-면 배열된 송수신 도파관 안테나를 T-형 레이더 모듈에 장착하여 안테나의 특성을 검출하였다. T-형 모듈에 장착된 송수신 안테나의 -10 dB 대역폭은 각각 1000 MHz (10.52 %)와 1090 MHz (11.47 %)로 측정되었고 격리도 (S21)는 요구 대역 내에서 -50 dB 이하로 측정되었다. 송수신 안테나의 최대이득은 각각 7.65 dBi와 7.26 dBi로 나타났으며 H-면 빔폭은 $64^{\circ}$, $65^{\circ}$로 측정되어 차량 측후방 레이더 센서용 안테나로 적합함을 확인하였다.