• International Journal of Fuzzy Logic and Intelligent Systems
• /
• v.5 no.2
• /
• pp.140-144
• /
• 2005

We investigate the P-generating functions, L-generating functions, and A-generating function, respectively induced by product t-norms, Lukasiewicz t-norms and additive semi-groups. Furthermore, we investigate the relations among them.

• Korean Journal of Microbiology
• /
• v.48 no.3
• /
• pp.180-186
• /
• 2012

Pseudomonas aeruginosa, a Gram-negative bacterium, is an ubiquitous and opportunistic human pathogen, which expresses many virulence factors through quorum sensing (QS) regulation. QscR, one of the QS signal receptors of P. aeruginosa, has unique features that make it possible to distinguish QscR from other QS receptors. In the present study, we focused on amino acid residues responsible for such a broad signal specificity of QscR. Thus we constructed mutant QscRs: $QscR_{T72I}$, $QscR_{R132M}$, and $QscR_{T140I}$ by substituting $72^{nd}$ threonine, $132^{nd}$ arginine, and $140^{th}$ threonine residues with isoleucine, methionine, and isoleucine, respectively by site-directed mutagenesis. When we examined the activity of these mutant QscRs, $QscR_{R132M}$ failed to respond to N-3-oxododecanoyl homoserine lactone (3OC12-HSL), but $QscR_{T72I}$ and $QscR_{T140I}$ remained the ability to respond to 3OC12-HSL despite much reduction of the sensitivity. When we treated a variety of acyl-HSLs with different structure, $QscR_{T72I}$ and $QscR_{T140I}$ showed better responsiveness to N-decanoyl HSL (C10-HSL) or N-dodecanoyl HSL (C12-HSL) that has no oxo-moiety at $3^{rd}$ carbon of acyl group than to 3OC12-HSL, and $QscR_{R132M}$ showed no responsiveness to any acyl-HSLs tested here. In addition, $QscR_{T72I}$ and $QscR_{T140I}$ were inhibited by 5f, a QscR inhibitor as similarly as wild type QscR was. These results suggest that while the $130^{th}$ arginine is crucial in both activity and acyl-HSL binding of QscR, the $72^{nd}$ and $140^{th}$ threonines are important in the activity, but they are little responsible for the discrimination of acyl-HSLs or competitive inhibitor.

• Journal of radiological science and technology
• /
• v.32 no.1
• /
• pp.95-99
• /
• 2009

The purpose of this research is to seek SPAIR's reversal time (TI) which satisfies two conditions ; maintaining the suppression ability of fat tissue and simultaneously minimizing the inhomogeneity of fat tissue in T2 high-speed spin echo 3.0T magnetic resonance image (MRI) of the brain, and to compare SPAIR with STIR which is fat-suppression technique. The reversal times (TI) of SPAIR protocol are set to 1/2, 1/3, 1/6 and 1/12 of SPAIR TR (420 msec), namely 210 msec (8 people), 140 msec (26 people), 70 msec (26 people) and 35 msec (18 people) and STIR TI is set with 250 msec (26 people). With these parameter sets, we acquired the axis direction 104 images of the brain. In ROI ($50\;mm^2$) of output image, signal intensities of the fatty tissue, the muscular tissue, and the background were measured and the CNRs of fatty tissue and the muscular tissue were calculated. The inhomogeneity of the fatty tissue is SD/mean, where SD is the standard deviation and 'mean' is a average fatty tissue signal. Consequently, SPAIR TI is determined on either 1/3 or 1/6 of TR (420 ms) ; 140 ms or 70 ms. Because the difference of statistics in fat-suppression ability and inhomogeneity of fatty tissue is very small (p < 0.001), Selecting 140 ms seems to be better choice for the image quality. Meanwhile, Comparing SPAIR (TI : 140 ms) with STIR, the fat-suppression is not able to be considered statistically (p < 0.252), but the image quality is able to be considered statistically (p < 0.01). In conclusion, SPAIR is better than STIR in the image quality.

• TTA Journal
• /
• s.33
• /
• pp.140-157
• /
• 1994

• Proceedings of the Korean Society of Applied Entomolohy Conference
• /
• 2001.05a
• /
• pp.140-140
• /
• 2001

• Journal of The Korean Astronomical Society
• /
• v.30 no.1
• /
• pp.71-81
• /
• 1997

We have studied the IR properties of molecular clouds in the region of the supershell GS234-02 using IRAS and COBE data. The mean values of dust color temperature and optical depth at $240{\mu}m$ are derived to be $15.4\pm1.5K\; and\;9.0\pm5.7\times10^{-4}$, respectively, which agree well with those determined by Sodroski et al.(1994) for the outer Galaxy. Mean IRAS colors, $R_{12}/100= 0.074,\; R_{25}/100= 0.052,\; R_{60/100}= 0.219$, indicate that the abundance of PAHs is enhanced but other particles are nearly the same as those of the solar neighborhood. We found the anticorrelation between $R_{100/140}\;and\;R_{140/240}$. It cannot be explained by the thermal emission of traditional big grains. The anticorrelation implies that, at high ISRF, $T_{100/140}$ underestimates the equilibrium temperature, while $T_{140/240}$ overestimates it and, at low ISRF, vice versa. Therefore we propose to use the intensity ratio, $R_{100/240}$ as a dust thermometer.

• Journal of Sensor Science and Technology
• /
• v.22 no.3
• /
• pp.185-190
• /
• 2013

We report on direct finding of how the morphology (i.e. filopodia width) of $CD4^+$ T lymphocytes correlates with the size of the quartz nanohohole arrays (QNHAs, 140, 200, 270, and 550 nm in diameter) via scanning electron microscopy (SEM). This research exhibits that the filopodia of $CD4^+$ T-lymphocytes extended on the QNHA substrates were observed to increase in width by increasing the size of QNHA in diameter from 140 to 550 nm. This strong linear response ($R^2$=0.988, n = 6) in filopodia's width of surface-bound $CD4^+$ T-cells with topographical structures of QNHA can be explained by contact guidance between the cells and solid-state substrates. Furthermore, this research suggests that the protruded filopodia of surface-bound T-lymphocytes can be used as a biosensor for sensing the topographical information of the nano-patterned substrates.

• Molecules and Cells
• /
• v.22 no.3
• /
• pp.308-313
• /
• 2006

Stromal cell-derived factor (SDF-1) is a CXC chemokine that selectively activates the CXCR4 chemokine receptor. Fibronectin is an intracellular matrix component that binds integrin and mediates cell-matrix adhesion. Activation of the integrin receptor can occur in two ways: by ligand binding (outside-in signaling), and in response to intracellular events (inside-out signaling). In the current study we showed that SDF-$1{\alpha}$ inhibited adhesion of T lymphocyte Jurkat cells resulting from binding high concentrations of fibronectin as well as that of THP-1 monocytes. The effect of SDF-$1{\alpha}$ on fibronectin-mediated adhesion was partly reversed by the CXCR4 receptor antagonist T140. Our results suggest that an SDF-1/CXCR4 signal pathway modulates fibronectin-mediated lymphocytes adhesion.

• Textile Coloration and Finishing
• /
• v.18 no.3 s.88
• /
• pp.42-48
• /
• 2006

The aim of this work is to develop Thick-Thin polyester yarn(T-T yarn) with finer than 1 denier mono filament. The manufacture of T-T yarns were carried out in a draw-winder using 85d/72f PET filament with various spinning speed of 2700, 2900, and 3100 m/min, respectively. The structure and physical properties of T-T yarns with spinning speed and over feed ratio were examined by draw-winder processing the sample in $100^{\circ}C$ water for 20 min and drying in 120, 140, 160, and $180^{\circ}C$ of dry air for 20 min. The crystallinity, the birefringence and the initial elasticity modulus of T-T yarns increased with increased spinning speed of filament and the heat treatment temperature but at the temperatures higher than $140^{\circ}C$ the increased rates show a tendency to decrease. Moreover, the initial modulus and the tenacity of T-T yarns increased with decreasing the over feed ratio of filament and the those of T-T yarns decreases with increasing the heat treatment temperature. The shrinkage of T-T yarns decreased with decreasing spinning speed and increased over feed ratio of filaments. Consequently, the results indicate that the best T-T yarn under 1 denier was optimized from PET filament with spinning speed of 2700 m/min and over feed ratio of 0.67

• Proceedings of the Korean Society of Broadcast Engineers Conference
• /
• 2004.10a
• /
• pp.113-140
• /
• 2004