• 한국응용과학기술학회지
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• 제5권2호
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• pp.39-54
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• 1988

The effects of exercise and selenium added high fat diet on edurance and serum lipid components were studied in rats. A total of 72 male Sprague-Dawley ($150{\pm}35g$, body weight) were divided into trained group and untrained group and were bred for 7 weeks. Each group had 6 different dietary subgroups; namely, basal diet, 20％ shortening and 20％ soybean oil subgroup and selenium (0.01mg％) added each subgroups. Exercises of 8-min treadmill running and 10-min swimming were given to the trained group every other day during the experimental period while only treadmill running was given to the untrained group during the last week. The amounts of food intake, changes in body weight and endurance were determined once a week and serum lipid components were measured before and after experimental period. Following are the results obtained : 1) The untrained group took a slightly larger amount of food than that in the trained group. The food efficiency is, however, higher in the trained group. Body weight increased more in untrained group, while high fat diet resulted in greater increment in body weight than that in normal diet groups. 2) The trained group showed remarkably longer endurance than the untrained group and selenium added high fat diet enhanced the effect. 3) The trained group showed lower blood level of T-chol., TG and TG/PL than the untrained group. All the other blood values of HDL-chol., PL, MDL-chol./T-chol., HDL/LDL and A/G ratio were higher in trained group. 4) Soybean oil added dietary groups exibited lower blood levels of T-chol., TG, TG/PL and A/G than those in shortening added dietary groups. On the contrary, the former groups showed higher blood HDL-chol., PL., HDL, HDL-chol. and HDL/LDL ratio than those of soybean oil added dietary groups. 5) $LDH_5$ was the most abundant one among serum LDH isozymes. The electrophoretic pattern of serum LDH isozymes was not changed by exercise training and selenium added high fat diet. 6) Exercise training lowered blood GOT and TBA. These effects were enhanced by soybean oil added diets. From the above results it was concluded that a regular and long term exercise training as well as a small amount of selenium added high fat diet result in reduction of body weight and TBA and improve dietary efficiency and physical endurance in rats.

• Journal of Acupuncture Research
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• 제21권1호
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• pp.99-110
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• 2004

Objective: The purpose of this study was to examine the different effects on labor pain, length of delivery time, and hemoglobin for primipara women treated by San-Yin-Jiao(SP-6) acupressure of 15 minutes or 30 minutes. Methods: The design of this study was a randomized clinical trial with two experimental groups and one control group, the participants included primiparas who underwent vaginal delivery. Data were collected using a structured questionnaire consisting of general characteristics with a subjective labor pain scale with VA.S, and length of delivery time and hemoglobin were collected in the medical record. Data was analyzed using descriptive statistics, x2- test, t-test, and ANCOVA. Results: There was statistically significant lower labor pain in the group of 30 minutes SP6 acupressure than the control group(t=7.733, p=.007), and there was statistically significant short length of delivery time in the group of 15 minutes SP6 acupressure than the control group(t=-2.230, p=.030). Conclusions: Even though we could not found a consistent effect with the SP6 acupressure, It was found that there was effect on shortening length of delivery time by 15 minutes of SP6 acupressure or lessening labor pain by 30 minutes of SP6 acupressure without risk of blood loss. It is necessary to replicate the study with a larger number of participants to find a consistent result.

• Journal of mucopolysaccharidosis and rare diseases
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• 제4권1호
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• pp.21-25
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• 2018

Fabry disease is a hereditary lysosomal storage disorder caused by the reduction or absence of lysosomal enzyme alpha-galactosidase A and the accumulation of glycosphingolipids, such as globotriaosylceramide (Gb3), in various organs, including the heart. The prevention of cardiac involvement in Fabry disease can only be achieved by enzyme replacement therapy (ERT), and the method of assessing the efficacy of ERT should be confirmed. Changes in the electrocardiogram, such as the shortening of PQ interval, prolongation of QTc and repolarization abnormalities as well as left ventricular hypertrophy in voltage criteria, can be used to identify Fabry disease patients; however, the usefulness of electrocardiograms for evaluating the efficacy of ERT is limited. The assessment of left ventricular hypertrophy using echocardiography has been established to evaluate the efficacy of ERT during long-term period. A new technique involving speckled tracking method might be useful for detecting early cardiac dysfunction and identifying the effect of ERT for a relatively short period. The estimation of left ventricular hypertrophy using cardiac magnetic resonance (CMR) is also useful for assessing the efficacy of ERT. Identifying late gadolinium enhancement in CMR may affect the effectiveness of ERT, and the new technique of T1 mapping might be useful for monitoring the accumulation of Gb3 during ERT. Histopathology in cardiac biopsy specimens is another potentially useful method for identifying the accumulation of GB3; however, the use of histopathology to evaluate of the efficacy of ERT is limited because of the invasive nature of an endomyocardial biopsy.

• 한국작물학회지
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• 제54권4호
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• pp.416-421
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• 2009

This experiment was conducted to find out optimum priming treatment conditions to the sesame seed as a preliminary study for enhancing sesame germination properties. Effective priming agents and concentrations for sesame seed were $K_3PO_4$, 200 mM and PEG6000, -1.0 MPa respectively. Optimum priming temperature and duration were $15^{\circ}C$, 4 days in view of germination speed and germination percentage. PEG6000 with -1.0 MPa was selected as an efficient priming treatment condition at $15^{\circ}C$, 4 days. This study suggested that priming treatment to sesame seed would be an effective technique enhancing sesame seed germination and shortening time to the $T_{50}$ at the field condition, but the efficiency of priming treatments to the sesame seed would be strongly dependent on individual or integrated conditions of priming agent, concentration, temperature and duration etc.

• 동의신경정신과학회지
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• 제19권1호
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• pp.43-54
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• 2008

Objective: The aim of this study is to evaluate the anticonvulsive effects of Gamiheichumhwan extract and to explain its action in GABAergic neuromodulation of the rat brain. Method: The extracts of Gamiheichumhwan were investigated for their inhibitory effect on GABA transaminase activity, their influence on brain GABA and glutamate levels, their agonistic activity on GABA/benzodiazepine receptor and anticonvulsive action using in vitro and in vivo assays. Results: 1. The extract inhibited dose-dependently GABA transaminase (GABA-T) activity by 4.6% and 18.9%, respectively at dosages of 250 mg/kg and 500mg/kg mouse (p.o.). 2. Brian GABA level was increased to 72.0% and brain glutamate level was decreased to 9.6% at a dosage of 500 mg/kg mouse (p.o.). 3. The extract suppressed [3H]Ro15-1788 binding to rat cerebral cortical membrane by $81.4{\pm}0.8%$ at a dosage of 3.2 mg, suggesting its agonistic activity on GABA/benzodiazepin receptor. 4. The extract showed anticonvulsive effect by lengthening the onset time of convulsion, shortening the convulsion duration and diminishing the lethality. Conclusion : It is suggested that Gamiheichumhwan can be used to somnipathy and adapted to treatment and prevention of epilepsy or convulsion.

• 대한전자공학회논문지SP
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• 제39권6호
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• pp.687-695
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• 2002

VoIP 음성 패킷 손실에 대한 대응 방안으로 제시되고 있는 매체 종속 FEC 기법은 통화 품질을 개선시키는 효과를 갖는데 반하여 한 프레임에 해당하는 추가지연이 발생하는 단점을 갖는다. 본 논문에서는 패킷 손실 복원에 사용되는 잉여 정보로 미래 프레임의 LSF 성분을 사용함으로써, 전송 지연을 줄이고 통화 품질을 개선할 수 있는 LSF FEC 기법을 제안하고 그 성능을 평가한다. 성능 평가를 위해서 VoIP에서 사용하는 ITU-T G.723.1, G.729 코덱을 Gilbert 손실 모델에 적용하고, PESQ 음질 측정 알고리즘을 사용하여 각 손실률 별로 MOS를 추정하는 방법을 사용한다. 본 논문에서 제안한 기법은 기존의 매체 종속 FEC 기법에 비해서 6.5ms∼27ms 이상의 지연 감소 효과를 가지고 있는 것으로 나타났으며, FEC를 적용하지 않은 경우와의 복원 음성 품질 비교 시뮬레이션 결과, 5% 정도의 현실적인 손실 환경에서 MOS 0.1 이상의 음질 개선 효과를 보였다.

• 한국동물위생학회지
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• 제46권1호
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• pp.29-34
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• 2023

Mycobacterium tuberculosis complex (M. tuberculosis complex) is a causative agent of contagious chronic disease in a wide range of mammalian hosts, mainly cattle, goat, pigs, wildlife, and humans. The definite diagnosis of tuberculosis is made based on culture of M. tuberculosis, but it takes a long time. In the present study, we analyzed whether the detection time of M. tuberculosis could be reduced when cultured in the medium containing the culture-promoting ingredients-107 (CPI-107) using the BacT/Alert 3D system, an automatic culture system. The time to detection (TTD) tended to decrease as the added concentration of CPI-107 increase. In the case of low numbers of M. tuberculosis, it decreased by 21.0% at 1.2 mg/mL of CPI-107 and by 15.9% in the case of high numbers of M. tuberculosis. In the culture using clinically isolated M. tuberculosis strains, the shortening of the culture time by CPI was more evident. In conclusion, the detection time of M. tuberculosis was shortened in the medium added with CPI-107, and this could be used for isolation, culture and drug susceptibility test of M. tuberculosis.

• 대한환경공학회지
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• 제28권1호
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• pp.1-6
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• 2006

본 연구에서 수행한 입상형의 발포 폴리스티렌을 이용한 고도처리 공정은 기존의 상용화되거나 개발중인 영양염류 처리공정에 비해 수리학적 체류시간을 상당히 줄일 수 있고 동절기에도 온도의 영향을 크게 받지 않는 장점을 가지고 있다. 도시하수를 이용하여 bench-scale 연구를 수행한 결과 T-N 제거효율의 경우 HRT 6 hr 및 4 hr에서 각각 약 55% 및 51%로서 HRT가 짧아졌을때 단지 약 4%의 처리효율 감소가 관찰되었다. 온도 영향에 있어서 여름철과 겨울철의 T-N 제거효율을 비교해본 결과 T-N 제거 효율이 각각 약 65% 및 54%로 관찰되어 여름철이 겨울철에 비해 약 11% 더 높은 효율이 관찰되었으며 겨울철 효율저하는 주로 암모니아성 질소의 질산화가 원활이 이루어지지 않았기 때문인 것으로 관찰되었다. 유입부하 및 C/N 비에 관한 연구에서는 유량 및 농도의 변화가 심한 하 폐수 처리에 있어서도 안정된 처리수질을 확보할 수 있었으며, C/N 비가 감소에 따른 처리효율 저하가 크지 않음을 관찰 할 수 있었다. 따라서 본 개발 시스템을 기존의 중 소규모 하수처리장에 적용할 경우 유입수내의 유기물을 최대한 활용하여 영양염류를 처리할 수 있을 것이라 기대된다.

• 대한지역사회영양학회지
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• 제6권5호
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• pp.726-733
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• 2001

This study was designed to investigate the effect of iron supplementation on the iron nutritional status and anemia of high school girls in Korea. One hundred thirty-five female students residing in Ulian metropolitan city in Korea diagnosed as having anemia or iron deficiency participated in this study. One or two tablets of iron medicine(80-160 mg Fe as ferrous sulfate/day) were administered to all participants for 3 months. Subjects were evaluated with a questionaire, measurement of hematological indices before and after iron supplementation. The average height and weight of respondents were 161.62 $\pm$ 4.68 cm and 53.87 $\pm$ 6.10 kg, respectively. Daily intakes of energy were 1597.8 $\pm$ 302.35 kcal(76.0% RDA). Iron intakes were 13.72 $\pm$ 4.17 mg (76.3% of RDA) and calcium intakes were 580.74 $\pm$ 177.21(72.5% of RDA) before iron supp]ementation. At baseline, 63% of all participants had depleted store(serum ferritin 12 ug/ml and/or transferrin saturation(TS) < 14%). After iron supplementation, this proportion declined to 19.3%. 55.6% of subjects had 12 ug/m1 of basal ferritin concentration before iron supplementation, and this proportion declined to 16.3% after iron supplementation. The basal hemoglobin(Hb) concentrations were 12.13 $\pm$ 1.01 g/dl and they increased to 12.79 $\pm$ 0.81 g/dl, which showed significant difference artier iron supplementation(p < 0.001). The basal ferritin and TS(%) were 13.24 $\pm$ 11.66 ng/ml, 18.42 $\pm$ 10.12% and they significantly increased to 32.95 $\pm$ 21.14 ng/ml, 33.53 $\pm$ 16.64%, respectively(p < 0.001). The basal total iron binding protein(TIBC) were 467.81 $\pm$ 97.24 ug/dl and they significantly decreased to 325.05 $\pm$ 48.89 ug/dl(p < 0.001) after iron supplementation. The number of tablets administered was positively correlated with serum iron(t = 0.553, p < 0.01), serum ferritin(t = 0.557, p < 0.01), TS(%)(t = 0.588, p < 0.01) and negatively correlated with TIBC(t= -0.409, p <0.01). The anemia symptoms such as ‘Shortening of breath when going upstairs(p < 0.01)’, ‘Tired out easily(p < 0.01)’, ‘Feeling blue(p < 0.001)’, ‘Decreased ability to concentrate(p < 0.01)’, and ‘Poor memory(p < 0.001)’improved significantly after iron supplementation. In this study, daily iron supplementations were efficacious in improving the iron status and anemic symptoms of female high school students. Regular check-ups and nutrition education for adolescents are necessary because of their vulnerability to iron deficiency. Further studies are needed to determine the minimum effective dose of iron and to examine the adverse effect of long-term iron supplementation.

• 대한공업교육학회지
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• 제33권1호
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• pp.149-168
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• 2008

이 연구의 목적은 공업계열 전문계고등학교의 디지털 논리 회로 과목에서 '조합 논리 회로'단원에 시뮬레이션 수업을 적용하여 학생들의 디지털 논리회로에 대한 학업성취도에 미치는 효과를 알아보는 데 있다. 이 연구를 위해 경상북도에 소재한 공업계열 전문계고등학교 3학년 2개 학급을 실험 집단과 통제 집단으로 선정하였고, 3개의 영가설을 설정하여 검증하였다. 실험 설계는 이질통제집단 전후검사 설계를 사용하였다. 실험은 총 6차시에 걸쳐 이루어 졌으며, 실험 집단에는 PSpice 시뮬레이션 수업을 적용한 후 브레드보드를 이용한 실습을 실시하였고, 통제 집단에는 전통적인 강의식 수업을 적용한 후 브레드보드를 이용한 실습을 실시하였다. 자료의 통계 처리는 SPSSWIN (ver 10.0) 프로그램을 사용하였고, 두 집단의 평균 차이가 통계적으로 유의미한지 알아보기 위해 유의수준 .05로 설정하여 독립표본 t-검증을 하였다. 이 연구에서 얻어진 결론은 다음과 같다. 첫째, 시뮬레이션 수업은 집단 유형에 따른 학업성취 전체 영역에 대해서는 효과적인 수업 방법이라고 할 수 없다. 그러나 심동적 영역에서는 학업 성취도 향상에 효과적이었다. 둘째, 시뮬레이션 수업은 학업 수준에 따른 학업성취 전체 영역에 대해서는 효과적인 수업 방법이라고 할 수 없다. 그러나 인지적 영역과 심동적 영역에서는 중 하위 집단에, 정의적 영역에서는 하위 집단에 효과적이었다. 셋째, 시뮬레이션 수업은 실습 소요 시간의 단축에 효과적인 수업 방법이라고 할 수 없다. 그러나 하위 집단의 실습 소요 시간의 단축에는 효과적이었다. 이상의 연구 결과 시뮬레이션 수업은 주로 심동적 영역에서 효과적이었고, 상위 집단보다는 하위 집단으로 갈수록 학업 성취에 있어서 효과적이라는 것을 알 수 있었다. 그러므로 다양한 교수 학습 방법을 활용함으로써 학습 효과를 높일 수 있다는 점을 시사해 준다.