• The Korean Journal of Nuclear Medicine Technology
• /
• v.13 no.1
• /
• pp.116-119
• /
• 2009

Background: Preanalytical factors can affect reliability of hormone assay results. Adrenocorticotropic hormone (ACTH) in blood is considered highly unstable because of proteolytic degradation, so storage of blood samples on ice until analysis is recommended. In clinical practice, however, this procedure may present logistical problems because most samples for ACTH measurement must be shipped from the place of sample collection to the laboratory. Therefore, we studied the impact of time and temperature before plasma separation and analysis on the results of ACTH assays. Methods: A total number of 22 patients were enrolled in this study. We obtained 2 blood samples. ACTH concentrations were 35~126 pg/mL. ACTH concentrations were measured by immunoradiometric assay (IRMA) using commercial kits (CIS Biointernational, Gif-sur-Yvette, France). Results: ACTH levels showed a significant difference between the samples of $22^{\circ}C$ EDTA and $4^{\circ}C$ EDTA. Measured ACTH concentrations significantly decreased with time before freezing at $-20^{\circ}C$. ACTH levels showed no significant difference between the groups of after storage for 24 hr without centrifugation at $22^{\circ}C$ and $4^{\circ}C$. Conclusion: We recommend that blood samples be obtained on pre-chilled EDTA collection tubes. The shortest possible time between sample collection and processing is always the best laboratory practice.

• Journal of Korean Society of Occupational and Environmental Hygiene
• /
• v.7 no.1
• /
• pp.33-48
• /
• 1997

Korean diffusive sampler (KDS) and charcoal tube (CT) were used for sampling n-hexane, trichloroethylene and toluene in air KDS was made by Department of Environmental Health, SNU-SPH in 1995. Surveys were conducted at ten industrial plants with organic solvents. The relationship between two sampling methods was examined by linear regression analysis, and concentrations by two sampling methods were compared using paired t-test. The results are as follows: 1. The geometric means by CT and KDS methods were 3.26ppm and 3.32ppm for n-hexane, 5.07ppm and 6.34ppm for toluene, and 7.18ppm and 7.90ppm for toluene, respectively. There was no significant difference between results by CT and KDS methods in three organic vapors (p>0.05). When linear regression analysis was performed, two sampling methods were highly related ; correlation coefficients were 0.98, 0.90 and 0.96 for n-hexane, toluene and trichloroethylene, respectively. 2. Airborne concentrations of n-hexane (n=21) were below 0.5 TLV level. The GM by two methods were almost same (3.09 ppm). And there was no significant difference between results by two methods (p>0.05). 3. Since toluene and trichloroethylene concentrations showed several levels, appropriate sampling rates were applied for each level. The GM of toluene concentrations by two methods at 0.5 TLV level were 3.75ppm and 5.48ppm. The KDS method overestimated the toluene concentrations at 0.5 TLV level (p<0.05). The GM values of toluene concentrations at 1 TLV level were 31.80ppm and 25.38ppm and at 2 TLV level were 64.13 ppm and 51.37 ppm. The KDS method underestimated concentration at both level (p<0.05). For trichloroethylene, the GM at 0.5 TLV level were 4.97 ppm and 7.11ppm. The KDS method overestimated the concentration of trichloroethylene (p<0.05). In conclusion, concentrations of three organic vapors measured by CT and KDS were not significantly different and results by two methods were highly related. But at contain concentrations, the levels by method were significantly different. Therefore, it is suggested that sampling rate of KDS should be studied simultaneously using CT method for organic vapors.

• Journal of Oriental Neuropsychiatry
• /
• v.26 no.2
• /
• pp.103-116
• /
• 2015

Objectives: Medical students suffer from mental health and academic problems due to academic stress. We investigated academic stress and exhaustion along with psychological issues caused by medical education during the years in the School of Korean Medicine. Methods: Two hundred fifty-one university students from the School of Korean Medicine, Pusan National University, were asked to complete the Medical Stress Scale (MSS), Maslach Burnout Inventory-Student Survey (MBI-SS), Positive Affect and Negative Affect Schedule (PANAS), and State-Trait Anxiety Inventory (STAI) three times during each semester for two years from 2013 onwards. We analyzed the influence of school term and vacation on educational stress and negative affect with the T-test. The Pearson's correlation analysis and regression analysis were used to predict changes during the first semester or first years of study in the School of Korean Medicine. Results: Academic stress and burnout increased steadily until the first semester of third grade, which was measured with MSS and MBI-SS. The anxiety level was highest when the students started the first grade and it decreased significantly after the first semester. Negative affect repeatedly increased significantly after each school term; however, it reduced after each vacation. In the first grade, 19.5% of the last measure of MSS can be explained with the first measure of MSS. Discussion: This study extensively reviewed the trends and characteristics of four years of academic stress and its related psychological influence, and discussed its importance for developing a more efficient academic curriculum for traditional Korean Medicine.

• Journal of Korean Public Health Nursing
• /
• v.10 no.1
• /
• pp.12-22
• /
• 1996

Currently. exchanges of industrial workers between countries are more active than ever. and the problem of AIDS in connection with the operation of preventive educational programs has reached a point where the issue cannot be limited to native people alone any more. Based on such judgement. this research has been carried out to provide basic study materials by grasping the latent factors representing the difference between countries in the levels of right knowledge. attitude and behavior with respect to AIDS maintained by workers who have grown in different social and cultural living background. During the period from Apr. 1. 1995 to Jun. 30. questionnaires. written both in Korean and English, were distributed to Korean and Malaysian employees working at certain Korean video manufacturers. and the results of replies. given by 80 workers who were analyzed through matched sampling· method where ages and sex matched by country. were used as the research materials. The gathered materials were analyzed through the SPSS package t-test. ANOVA. factor analysis and multiple stepwise regression methods. and the following results were obtained. 1. The 2 extracted latent factors could be named 'common. social' knowledge factor and 'in-depth. psychological' knowledge factor respectively. 2. The percentile points of 'external. social' knowledge factor. in the case of Korean workers. howed 90.0 at average. a figure 13.75 points higher than those of Malaysian workers. 76.25. On the other hand. the percentile points of the 'in-depth. psychological'knowledge factor showed 70.80 at average in the case of Korean workers. a figure 7.47 points lower than those of Malaysian workers. 78.33. Meanwhile. the difference in percentile points between the 2 latent factors was 8.54 at average. indicating that the points of 'in-depth. psychological' knowledge factor was lower than those of the 'external. social' knowledge factor. 3. As for Korean workers. the percentile points of the 'in-depth. psychological' knowledge factor showed higher points in office workers than in non-office workers. and such variables exhibited in the position of workers can explain the $7\%$ of the latent factor. The percentile points of the 'in-depth. psychological' knowledge factors. in the case of Malaysian workers. showed higher points in groups who had religion than in groups who did not. and higher points in groups who obtained information from newspapers than in groups who obtained from televisions or other sources; and with these 2 variables. $26\%$ of this latent factor can be explained. The results. of analysis described so far suggest that while Korean workers possessed general level of knowledge on AIDS. they had low level of practical knowledge as far as its depth is concerned. and that they had social prejudice on patients as well as on the AIDS infection route. In addition. because the overall knowledge level of Malaysian workers. is lower than that of Korean workers. it suggests that separate programs intended for Malaysian workers are required prior to executing integrated programs.

• Geotechnical Engineering
• /
• v.13 no.5
• /
• pp.75-88
• /
• 1997

In this study an iterative procedure for the analysis of drilled shafts was proposed on the basis of the load transfer mechanism. Special attention was given to the estimation of bearing capacity of drilled shafts which was compared with driven piles, and then with the results of pile load test. The load displacement at the pile head was calculated by load than sfer curves (t -z curves, q-z curves) by using Vljayvergiya, Castelli and hi -linear models. Bab ed on the analytical results, it is found that the behavior of drilled shafts is different from that of driven piles the smaller the skin friction mobilized at the pile-boil interface, the smaller the development of the bearing capacity. Hence the greater pile head movement is required to mobilize the same mainitride of bearing capacity. This trend is more noticeable in sand than in clay. It is also found that as the length-todiameter ratios increase, the dirtference of ultimate bearing capacity between drilled shafts and driven piles is becoming lass ger in sand, but it is minor in clay.

• Journal of Families and Better Life
• /
• v.9 no.1 s.17
• /
• pp.113-130
• /
• 1991

The purpose of the present study was to describe the expectation and the performance on the housework socialization of the age homemakers and to ivestigate their relationships to the demographic characteristics and the influences of other related factors. 344 homemakers who were older than 45 years and were living in Chunlabuk-do, 1990 were sampled for this study. The data were collected by questionnaire designed by the researcher and analyzed by using frequency, one-way ANOVA analysis of variance, t-test, and multiple regression analysis. The major findings were as follows ; 1) The aged homemakers' housework socialization score was higher than the average, The score of the expectation was higher than one of the present performance. Scores for the utilization of the household equipments and the utilization of employes's services were higer comparing to those for other variables of the performance and the expectation respectively. 2) There was the significant differences in the each of the present performance varibles related to th housework socialization among the following demographic varables ; Age of homemakers, years of marriage, education, residence area, types of housing, monthly income, and level of housework equipment possession. 3) There was the significant differences in the expectation on the housework socialazation among the following variables ; age of homemakers, years of marriage, education, monthly income, and types of housing. The significant differences were found in the utilization of grouped, the utilization of the commodity, the utilization of the household equipments as subvariables of housework socialization, among age of homemakers, years of marriage, and level of education, The significant differences were found in the utilization of employee's services among age of homemakers, types of family, and level of health. 4) The level of education and monthly income significantly influenced on the present performance of the house work socialization. Years of marriage, significantly influenced on the utilization of grouped, education on the utilization of the commodity.(the utilization of the producted materials) and the utilization of employee's services and monthly income on the utilization of the household equipments (the utilization of the household appliances, and equipments). The years of marriage and education significantly influenced on the expectation on the housework socialization in the order, Age of homemakers and years of marriage significantly influenced on the utilization of grouped, the utilization of the commodity, the utilization of employee's services and age of homemakers and monthly income on the utilization of the household equipments.

• Journal of Korean Medical Ki-Gong Academy
• /
• v.10 no.1
• /
• pp.46-73
• /
• 2007

In this study, the researcher tried to present the groundwork to prepare the oriental medical yangseng plan for the future obesity with the comparison between yangseng level and the obesity of workers. The researcher made up the questionnaire which asks the general character, health-related character and yangseng level, projected among 560 people. All collected material was analyzed by SPSS and tested by T-test and ANOVA. 1. The general yangseng level average is 3.27, morality yangseng 3.90, sleep yangseng 3.39, mind yangseng 3.31, sex life yangseng 3.30, exercise yangseng 3.15, activities and rest yangseng 3.08, diet yangseng 2.94, seasonal yangseng 2.84. The highest is morality yangseng and seasonal yangseng is the lowest. 2. In the aspect of yangseng level: Having a spouse, Non-smoking, Regular exercising, Sufficient sleeping have higher yangseng levels. 3. Obesity related index is changing into the higher level when he/she is older, more paid, more job experience, more education background but less metabolic calory. And drinking and regular exercising have relativity with body composition analysis. 4. After comparing yangseng level with body composition analysis, we can easily find that the more visceral fat, the higher WHR has a high yangseng level. The more mineral also has a high mind yangseng and a low diet yangseng. The visceral fat level has a high yangseng level when higher morality yangseng and mind yangseng are getting higher and higher. And sex life yangseng shows that the highest yangseng level is from 9-10 visceral fat and the lowest yangseng level is from below 4 visceral fat. The higher WHR, the higher morality, mind and sleep yangseng. The heavier, the lower diet yangseng. The mind yangseng was very high when body fat rate was higher. The more body fat, the higher morality yangseng. The higher yangseng, when we have more muscle. Yangseng level and obesity of laborer has a close relationship with individual character and daily habits. Also, relevance can be easily found between yangseng level and obesity. Now the researcher came into the conclusion that we need to control over laborers' health and prevention of their obesity.

• Asian-Australasian Journal of Animal Sciences
• /
• v.29 no.11
• /
• pp.1632-1638
• /
• 2016

A study was conducted to compare the endogenous basal losses of phosphorus (EBLP) in pigs fed diets containing gelatin (GEL) or spray-dried porcine plasma (SDPP) as protein sources and to determine the standardized total tract digestibility (STTD) of phosphorus (P) in SDPP. The trial was carried out at the Federal University of Santa Maria, Brazil. Twelve castrated pigs with an initial body weight of 55 kg were individually allotted in metabolic crates during two 12-day periods, each with 7 days of adaptation and 5 days of total fecal collection. The beginning and the end of the collecting periods were determined according to the marker-to-marker approach, using ferric oxide as an indigestible marker. Pigs were submitted to four semi-purified diets, one being a P-free diet with 30% of GEL as the protein source and three were diets with 10%, 20%, and 30% inclusion of SDPP respectively. Data were subjected to analysis of variance and the model included the effects of period, animal and treatments; the results of the three diets with increased levels of SDPP were subjected to linear regression analysis. The intercept of the relation of between ingested P and absorbed P represented the EBLP, while the slope indicated the STTD of P in SDPP. The EBLP means obtained by P-free diet and regression method were compared with the Student t test. The EBLP were 128.95 mg/kg dry matter intake (DMI) and 153.63 mg/kg DMI (standard error = 77.0; p<0.06) using the P-free diet with GEL as the protein source and the regression method, obtained with diets containing increased levels of SDPP, respectively. The apparent digestibility of P was 87.9%, 94.2%, and 92.9% for the treatments containing 10%, 20%, and 30% inclusion of SDPP, respectively. The estimated STTD of P obtained with the linear regression was 97.4%. When the EBLP estimated by the P-free diet was used to corrected the apparent digestibility of P in diets containing SDPP, the STTD of P in SDPP was 96.9%, 98.8%, and 95.9% for 10%, 20%, and 30% SDPP, respectively. Therefore, it can be concluded that SDPP can replace GEL to estimate the endogenous losses of P. In addition, the STTD of P in SDPP estimated with the P-free diet was 97.2% and it was 97.4% by the regression method, utilizing SDPP.

• Journal of Yeungnam Medical Science
• /
• v.24 no.2
• /
• pp.296-304
• /
• 2007

Background : The main aim of this study was to analyze the factors that could be used to predict job satisfaction of assistant nurses in general hospitals. Material and Methods : This study was based on a survey of assistant nurses in the Daegu region from January 1, 2006 to January 31, 2006. Originally 300 questionnaires were distributed and among them 291 were completed. The data was collected and used for the statistical analysis. Descriptive and inferential statistics, such as the frequency, t-test and one-way ANOVA were used for the analysis. Results : Among the respondents, the average score for job satisfaction was lowest in the university-trained nurses and highest in the nurses who had only graduated from high school. Conclusion : The working conditions, work place and motivation are significantly associated with job satisfaction. In particular, there was lower job satisfaction in those nurses who wanted to change their occupation.

• Asian Pacific Journal of Cancer Prevention
• /
• v.16 no.4
• /
• pp.1471-1477
• /
• 2015

Background: Adding taxanes to adjuvant antracycline and cyclophosphamide (AC) in combination may provide significant improvement in node-positive and high risk node-negative breast cancer (BC) patients. However, the optimal dose and the role of dose-dense (DD) chemotherapy have yet to be determined. The aim of this study was to compare the efficacy of a DD paclitaxel (P)-AC combination with conventional weekly P-AC or docetaxel D-AC combinations in patients with node-positive breast cancer. Materials and Methods: Newly diagnosed 280 node-positive BC patients diagnosed from 1998 to 2013 in three clinics were retrospectively analyzed. Demographic and medical data were collected from the medical charts. Patients were categorized to 3 groups according to treatment arms: arm A, ddAC-P; arm B, weekly P and AC combination; and arm C; T and AC combination. Adjuvant trastuzumab was added for HER2-positive patients. Kaplan-Meier survival analysis was carried out for disease free survival (DFS) and overall survival (OS). The log-rank test was used to examine the statistical significance of the differences observed between the groups. Two-sided P values <0.05 were considered statistically significant. Results: Of the total of 280 patients, 101 were in arm A, 114 in arm B and 65 in arm C.The median ages were 49, 50 and 46, respectively (p=0.11). Median follow-up was 39 (3-193) months. Stage, lymphovascular and perineural invasion, receptor patern, and menopausal status were similar in the 3 treatment arms, but HER2 positivity was significantly lower in arm A, compared to arms B and C (25.7%, 53.1%, 41.5% in arms A, B and C, respectively; p<0.001). Also grade 3 tumors were significantly less frequent in treatment arm A compared to arm B and C (27.3%, 56.8% and 49.2%, respectively, p=0.01). Afterunivariate and multivariate analysis were performed, 3-year DFS rates were 89%, 81%, and 75%, respectively (p=0.12) and three year OS rates were 96.6%, 89%, and 75% (p=0.62). Conclusions: In this study, no significant difference was found between adjuvant dose dense and conventional taxane treatment regimens.