• 제목/요약/키워드: T-lymphoma

검색결과 237건 처리시간 0.021초

외과적 치료 없이 관해된 피부 역형성 대세포 림프종 1예 (A Case of Multifocal Primary Cutaneous Anaplastic Large Cell Lymphoma Managed without Surgical Treatment)

  • 임준호;박언주;은석찬
    • 대한두경부종양학회지
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    • 제35권2호
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    • pp.77-80
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    • 2019
  • Primary cutaneous anaplastic large cell lymphoma (C-ALCL) is rare among skin malignancies. C-ALCL usually manifests as reddish or violet nodules. Surgical excision or radiation therapy is generally considered as first-line therapy, but a clinically aggressive disease may require multiagent chemotherapy. Establishing a proper diagnosis of C-ALCL is challenging but should be made to avoid inappropriate treatment and its consequences. The authors report a case of medically resolved C-ALCL in an 81-year-old man presented with well-defined nodular lesions on the forehead.

역형성 대세포 림프종의 세침흡인 세포학적 소견 - 악성 섬유성 조직구중을 닮은 1예 보고 - (Fine Needle Aspiration Cytology of Anaplastic Large Cell Lymphoma - A case mimicking malignant fibrous histiocytoma -)

  • 이정원;오영륜;고영혜
    • 대한세포병리학회지
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    • 제9권1호
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    • pp.99-104
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    • 1998
  • Anaplastic large cell lymphoma(ALCL) is an uncommon type of non-Hodgkin's lymphoma(NHL) populated with anaplastic, often bizarre cells that express CD30 (Ki-1) antigen. The unusual histologic and cytologic features may cause confusion with other neoplasms, such as poorly differentiated carcinoma, melanoma, Hodgkin's disease, or true histiocytic lymphoma. Although the cytologic features of ALCL have been well described, there are few reports about cytologic findings of the sarcomatold variant of ALCL. We experienced a case of fine needle aspiration(FNA) cytologic findings of ALCL which mimicks malignant fibrous histiocytoma. FNA cytology of chest wall mass in a 62-year-old female with a history of peripheral T-cell lymphoma(Lennert lymphoma) revealed a heterogeneous population of single cells and poorly cohesive cells with large, pleomorphic nuclei and spindle cells gathering around vascular structures within an inflammatory background. Additional features of the neoplastic cells were eccentric, multilobated nuclei with occasional 'wreath-like' configuration; abundant cytoplasm with vacuolization; and prominent nucleoli. The cytologic features suggested sarcoma, especially malignant fibrous histiocytoma. The diagnosis was made retrospectively with an aid of immunocytochemical staining.

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이하선과 상경부에 동시 발생한 외투세포 림프종 1예 (A Case of Mantle Cell Lymphoma Involving the Parotid Gland and Upper Neck)

  • 곽슬기;김춘동;김윤정;김승우
    • 대한두경부종양학회지
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    • 제31권1호
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    • pp.43-46
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    • 2015
  • The Mantle cell lymphoma(MCL) is a relatively rare subtype of malignant lymphoma characterized by chromosomal translocation t(11 ; 14)(q13 ; q32), positive response for CD5, and nuclear cyclin D1. It is account for an estimated 3-6% of all non-Hodgkin's lymphoma. The involvement of extra-nodal site is not uncommon, whereas salivary glands are rarely affected. It is more commonly occurred in men and old age and approximately 75% of cases are diagnosed with advanced stage. It is usually characterized by an aggressive clinical course, and the prognosis is poorer than other type of head and neck lymphoma. We recently encountered a 69-year-old female with mass in parotid tail and upper neck, and it was diagnosed as mantle cell lymphoma. We report the unique case with a review of literature.

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미만성 거대 B세포 림프종 환자의 한의약치료 증례보고 (Case of a Diffuse Large B-Cell Lymphoma Patient Treated with Traditional Korean Medicine Treatment)

  • 김인수;정민성;오현승;이영수
    • 동의생리병리학회지
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    • 제28권2호
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    • pp.233-237
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    • 2014
  • This case report that the therapeutic effects of traditional Korean medicine(TKM) treatment on the tumor response in a diffuse large B-cell lymphoma(DLBL) patient. A patient was treated by acupuncture, pharmacopuncture, moxibustion, cupping and herbal medicine once a week at least for 12 months. we evaluated the grade of chief complaints and performed blood tests and sonography, abdominal CT periodically. After 1 month administration with TKM treatment, the symptoms of the patient vanished obviously. the size of inguinal lymphoma decreased gradually through 3 months. then from 3 to 10 months, the size of inguinal lymphoma remained as it is. TKM treatment was maintained continuously. in the abdomino-pelvic CT performed after 12 months, the patient didn't complain any symptom and the size of inguinal lymphoma decreased a little again. This case study supports that TKM treatments may have a efficacy in treating diffuse large B-cell lymphoma(DLBL) patients.

종괴로 발현한 원발성 폐 혈관중심성 림프종 1예 (A Case of Primary Pulmonary Angiocentric Lymphoma Manifested as a Mass)

  • 권형주;박영우;이무열;이철호;김진관;김미영;황인석;유흥선;황순철
    • Tuberculosis and Respiratory Diseases
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    • 제46권3호
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    • pp.426-431
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    • 1999
  • 저자등은 건성기침을 주소로 내원하여 단순 흉부 방사선 촬영검사 소견상 우측 폐야에 거대종괴가 관찰되어 우하엽 절제술 및 면역조직화학 검사상 T 세포 기원의 혈관중심성 림프종으로 진단받은 1예을 경험하였기에 보고하는 바이다.

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피하 지방층염양 T-세포 림프종의 F-18 FDG PET/CT 소견 (F-18 FDG PET/Cl Findings of Subcutaneous Panniculitis - like T- Cell lymphoma: A Case Report)

  • 공은정;조인호;천경아;배영경;최준혁;현명수
    • Nuclear Medicine and Molecular Imaging
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    • 제43권3호
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    • pp.240-244
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    • 2009
  • F-18 FDG PET is a metabolic imaging modality that is efficacious in staging and assessment of treatment response for variety of lymphomas. We report usefulness of F-18 FOG PET/Cl in evaluating severity of the disease and response to therapy in a patient with subcutaneous panniculitis- like T-cell lymphoma (SPTCL). Here we describe a case of SPTCL in 24-year-old man who had wide spread firm and tender nodular lesions with increased F-18 FOG uptake. After chemotherapy follow up F-18 FDG PET/CT image shows disseminated malignancy and then the patient died with hemophagocytic syndrome. This report suggests that F-18 FDG PET/CT may be useful in determining disease activity at the time of initial diagnosis, after treatment, and evaluating a suspected outcome of SPTCL.

Epstein-Barr 바이러스 인사이투 보결합 시행시 양성대조표지로서의 버키트 림프종 세포주 (CCL85 EB-3)의 응용 (Application of Epstein-Barr Virus Cell Lines (CCL85 EB-3) in Performing the EBER mRNA In Situ Hybridization as a Positive Control)

  • 김성숙;한운섭;서주영;허주령
    • 대한세포병리학회지
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    • 제7권1호
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    • pp.38-43
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    • 1996
  • Epstein-Barr virus(EBV) is associated with a wide spectrum of benign and malignant disorders including leukoplakia, Hodgkln's lymphoma, central nervous system lymphoma, peripheral T cell lymphoma and nasopharyngeal undifferentiated carcinoma. There are several distinctive aspects of biology of the virus that are important in investigation of virus in clinical specimens. The abundant expression of the EBER mRNA transcripts makes possible the sensitive detection of latent expression in EBV-associated tumors. Although there has been a dramatic increased interest in the direct characterization of EBV in clinical specimens, there have been few studios about the effective and reliable positive controls in performing in situ hybridization technique for EBV, especially on paraffin-em bedded tissue. We applied Burkitts lymphoma ceil line as positive control in EBV in situ hydridization using Oncor Kit. The cell block of Burkitt lymphoma cell line(CCL85 EB-3) showed strong and specific positivity for EBER in situ in nuclei of EBV infected cells.

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자궁경부 악성 림프종의 경부-질 도말소견 - 1 증례 보고 - (Cytologic Features of Malignant Lymphoma of the Uterine Cervix - A case report -)

  • 김남훈;박찬금;고영혜;박문향;이중달
    • 대한세포병리학회지
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    • 제6권1호
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    • pp.76-79
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    • 1995
  • The uterine cervix is an uncommon site of primary non-Hodgkin's lymphoma (NHL). Although the cytologic findings of NHLs are well known, most cervicovaginal smear of uterine NHLs give lower diagnostic yield than common epithelial malignancy because abnormal cells do not appear in the sample in the absence of surface ulceration. Herein, we describe cytologic findings of a case of uterine cervical NHL which was initially diagnosed by cervicovaginal smear. The tumor cells were relatively uniform, isolated, large-sized with scanty cytoplasm and round or indented nuclei. The nuclei had stippled chromatin and small nucleoli. Histologically and immunohistochemically the tumor was proven to be large cell lymphoma of T-cell lineage.

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Primary Diffuse Large B-Cell Lymphoma of the Seminal Vesicle: a Case Report

  • Kwag, Kyung Su;Jang, Suk Ki;Yeon, Jae Woo;Kwon, Kye-Won;Son, Jeong Hwan;Kim, Hyuk Jung
    • Investigative Magnetic Resonance Imaging
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    • 제20권4호
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    • pp.259-263
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    • 2016
  • Primary diffuse large B-cell lymphoma of the seminal vesicle is an extremely rare disorder, with only two cases reported in the English literature. Here, we present imaging findings of a case of primary diffuse large B-cell lymphoma of the seminal vesicle. On transrectal ultrasonography, the mass presented as a 3.0-cm-sized heterogeneous, hypoechoic lesion in the right seminal vesicle. Computed tomography (CT) revealed a mass with rim-like enhancement in the right seminal vesicle. On magnetic resonance imaging (MRI), the tumor showed iso-signal intensity on T1-weighted images and heterogeneously intermediate-high signal intensity on T2-weighted images. The tumor showed rim-like and progressive enhancement with non-enhancing portion on dynamic scanning. Diffusion restriction was observed in the mass. On fluorodeoxyglucose positron emission tomography-computed tomography (FDG PET/CT) imaging, a high standardized uptake value (maxSUV, 23.5) by the tumor was noted exclusively in the right seminal vesicle.