• 제목/요약/키워드: T-lymphoma

검색결과 235건 처리시간 0.027초

Non-epitheliotropic Cutaneous T-cell lymphoma in a cat: a case report

  • Jeon, YeSeul;Bae, Hyeona;Shin, Sun Woo;Cho, ARom;Kim, Young Ju;Hwang, Tae Sung;Lee, Hee Chun;Hyun, Jae-Eun;Cho, Kyu-Woan;Jung, Dong-In;Kim, Dae-Yong;Yu, DoHyeon
    • 대한수의학회지
    • /
    • 제62권2호
    • /
    • pp.13.1-13.5
    • /
    • 2022
  • Cutaneous lymphoma is rare in cats. An 11-year-old spayed female Persian cat presented with crust, ulceration, and multiple nodules on the shoulder and forelimb for 2 months. Computed tomography revealed a diffuse, irregularly margined lesion in the dorsal cutis extending from cervical to thoracic vertebrae. Cytological evaluation predominantly revealed large round cells with multilobulated nuclei and basophilic cytoplasm. Histopathological examination confirmed round CD3+/PAX5-cells packed in the dermis. Thus, the diagnosis of non-epitheliotropic cutaneous lymphoma with a diffuse large T-cell type was made. The disease progressed rapidly for the next 2 weeks, and the owner elected humane euthanasia.

Treatment of canine CD3+/CD21+/CD45- T-zone lymphoma with chlorambucil and prednisolone in two dogs: case reports

  • Hee-Tae Park;Jeong-Min Lee;Hyeon-A Bae;Do-Hyeon Yu;Dong-In Jung;Kun-Ho Song;Joong-Hyun Song
    • 대한수의학회지
    • /
    • 제63권4호
    • /
    • pp.38.1-38.6
    • /
    • 2023
  • Canine T-zone lymphoma (TZL) is an indolent form of T-cell lymphoma. Conservative management is usually recommended; however, chemotherapy may be considered for symptomatic or progressive cases. Herein, we describe two dogs with generalized peripheral lymphadenopathy and peripheral blood lymphocytosis at presentation. One dog presented with gross lesions on the tongue. Flow cytometric immunophenotyping and cytological examinations demonstrated findings consistent with those of TZL. Chemotherapy with chlorambucil and prednisolone was administered, which resulted in improvement of the condition without any adverse events. Chemotherapy with chlorambucil may be considered as an appropriate choice for treating canine TZL.

Low Dose Ultraviolet Al (340-400 nm) Phototherapy for Erythrodermic Cutaneous T-cell Lymphoma

  • Uede, Koji;Hiroi, Akihisa;Nakamura, Tomoyuki;Kishi, Tomoo;Yamamoto, Yuki;Furukawa, Fukumi
    • Journal of Photoscience
    • /
    • 제9권2호
    • /
    • pp.503-505
    • /
    • 2002
  • Three patients suffering from widespread erythrodermic cutaneous T-cell lymphoma were treated with low-dose UVAI phototherapy with a single dose of 20 - 30J/$cm^2$, resulting in cumulative doses of 520 - 1890 J/$cm^2$. Two patients showed complete responses, while other had a partial improvement.

  • PDF

결핵성 만성 농흉벽에 원발한 T 세포형 악성 임피종;1례 보고 (T-cell Non-Hodgkin`s Lymphoma originating in the wall of Chronic Tuberculous Empyema - One Case Report -)

  • 송우철
    • Journal of Chest Surgery
    • /
    • 제25권10호
    • /
    • pp.1102-1106
    • /
    • 1992
  • A 66-year-old male patient was admitted due to chest pain and dyspnea of 1 year duration, He had history of treatment for tuberculosis and pleurisy, about 40 years ago. At another hospital the patient underwnt closed thoracostomy drainage for six months, and thereafter the symptom gradually aggrevated. Under the diagnosis of chronic tuberculous empyema, decortication was performed. The peel attached to the posterolateral aspect of chest wall, there was an area of soft tissues with pale-brown discoloration, extending to intercostal muscles, but sparing overlying muscles. The biopsy specimen of the lesion was pathologically diagnosed as diffuse, large T-cell non-Hodgkin`s lymphoma. A review of the literature showed that malignant lymphoma of this type have been reported exclusively from Japan but never from other countries including Korea. After 1 year of followup period, the patient is well and stable.

  • PDF

Relapsed extranodal NK/T-cell lymphoma in the mandible, Nasal Type: a case report and review of the literatures

  • ;;;김성곤
    • Journal of the Korean Association of Oral and Maxillofacial Surgeons
    • /
    • 제37권4호
    • /
    • pp.329-332
    • /
    • 2011
  • Extranodal NK/T-cell lymphoma (NTCL), nasal type is rare and highly fatal malignant neoplasm. Early diagnosis and establishing treatment plan are very difficult. Furthermore, NTCL in the mandible is an extremely rare condition. The clinical significance of presented case is the very rare location of NTCL. To the best of author's knowledge, this is the first reported case of NTCL of the mandible in the literature.

Cutaneous epitheliotropic T-cell lymphoma with Sézary syndrome in a dog

  • Lee, Song in;Lee, Han Joon;Seo, Kyoungwon;Song, Kunho
    • 한국동물위생학회지
    • /
    • 제44권4호
    • /
    • pp.309-313
    • /
    • 2021
  • A 12-year-old, spayed female, Toy-poodle dog presented in progressive, pruritic carpal mass and mandibular papule. The skin lesions and enlarged superficial lymph nodes were surgically removed. According to histopathology and immunohistochemistry, the patient diagnosed as cutaneous epitheliotropic T-cell lymphoma with lymph node metastasis. Chemotherapy with L-asparaginase, lomustine and prednisolone was initiated. The patient deteriorated despite treatment and was admitted to the hospital. Blood tests revealed significant leukocytosis. Circulating large lymphocytes with convoluted and cerebriform nuclei seen in peripheral blood led to presumption of Sézary cells. Thus, considering skin, lymph nodes and blood involvement, Sézary syndrome was diagnosed.

두경부 혈관중심성 T세포 림프종의 발생주위 및 병기별 치료결과 (Optimal Treatment Results of Angiocentric T Cell Lymphoma in Head and Neck according to the Subsites and Stage)

  • 최종욱;김정준;유찬기;팽재필;김형진;정광윤;최건
    • 대한두경부종양학회지
    • /
    • 제16권1호
    • /
    • pp.33-36
    • /
    • 2000
  • Objectives: Angiocentric T-cell lymphoma of the head and neck is an angiocentric and angiodestructive lymphoreticular proliferative disorder. It has been treated with various treatment modalities, but its prognosis is poor and the treatment modality is controversial. We performed this study to suggest a treatment modality with improved results. Materials and Methods: We studied 40 cases of pathologically confirmed angiocentric T-cell lymphoma from July 1984 to December 1996, 35 cases of which showed complete response after initial treatment. All the patients were divided into two groups according to treatment modality. 15 cases received radiotherapy alone (Group I) and 20 cases received radiotherapy after five cycles of CHOP-Bleo chemotherapy(Group II). We analyzed the subsites of tumor, stage, treatment modality and treatment outcome and causes of failure for each group, and compared the three-year no evidence of disease(NED) between the two groups. Results: The three-year NED of a combined chemoradiotherapy was higher than that of a radiotherapy alone (p=0.0478). The three-year NED according to groups and stage were as follows: Group I=6/15(40.0%), stage IE=5/10(50.0%), stage IIE=1/5(20%), Group II=13/20(65.0%), stage IE=9/13(69.2%), stage IIE=4/7(57.1%). Radiotherapy alone is not well effective for the nasal cavity lymphoma extended to paranasal sinus and the palate. Conclusion: We are unable to provide clear guidelines for treatment, but recommend the initial treatment with oral alkylating agents and steroids followed by radiotherapy for Ann Arbor stage II tumors and stage I of the palate lymphoma and the nasal cavity lymphoma extended to paranasal sinus.

  • PDF

양측 미만성 폐침윤과 전신 홍반을 동반한 말초 T세포 림프종 (A Case of Peripheral T-cell Lymphoma with Diffuse Bilateral Pulmonary Infiltration and Whole Body Rash)

  • 이승현;하은실;김정하;정진용;이경주;김세중;이은주;허규영;정기환;정혜철;이승룡;이상엽;김제형;신철;심재정;인광호;강경호;유세화
    • Tuberculosis and Respiratory Diseases
    • /
    • 제59권5호
    • /
    • pp.566-570
    • /
    • 2005
  • 폐에 발생하는 원발성 비호지킨 림프종은 아주 드문 질환으로 대개 폐문이나 중격동의 림프절 비대로 나타난다. 조직학적으로 대개 low grade B-cell 형태로 주로 발생하고 말초 T세포 형태로 폐에 원발성으로 발생하는 림프종은 드문 것으로 알려져 있다. 저자들은 발열과 전신 홍반이 있으면서, 흉부 X-선 사진상 급속히 진행하는 미만성 폐침윤 및 흉수 소견을 보여 초기에는 감염성 질환을 의심하였으나 피부병변과 림프절 및 골수 검사상 말초 T세포 림프종으로 진단된 예를 경험하였기에 문헌 고찰과 함께 보고하는 바이다.

Extranodal Malignant Lymphoma Concurrent Involving Female Urethra and Cervix: a Case Report

  • Kim, Dong Chan;Kim, You Me
    • Investigative Magnetic Resonance Imaging
    • /
    • 제24권3호
    • /
    • pp.168-173
    • /
    • 2020
  • Extranodal lymphoma presents in almost one-third of all non-Hodgkin lymphoma cases. The gastrointestinal tract, skin, and central nervous system are common sites of involvement, whereas the urethra and cervix are very rare. To the best of our knowledge, this is the first report on concurrent extranodal involvement of the uterine cervix and urethra. We report imaging findings of malignant lymphoma involving urethra and cervix concurrently in a 79-year-old female patient with literature review. The magnetic resonance imaging showed huge intermediate to high signal intensity mass on T2 weighted images and strong homogeneous enhancement in uterine cervix and periurethral area, but no surrounding architectural disruption.

외과적 치료 없이 관해된 피부 역형성 대세포 림프종 1예 (A Case of Multifocal Primary Cutaneous Anaplastic Large Cell Lymphoma Managed without Surgical Treatment)

  • 임준호;박언주;은석찬
    • 대한두경부종양학회지
    • /
    • 제35권2호
    • /
    • pp.77-80
    • /
    • 2019
  • Primary cutaneous anaplastic large cell lymphoma (C-ALCL) is rare among skin malignancies. C-ALCL usually manifests as reddish or violet nodules. Surgical excision or radiation therapy is generally considered as first-line therapy, but a clinically aggressive disease may require multiagent chemotherapy. Establishing a proper diagnosis of C-ALCL is challenging but should be made to avoid inappropriate treatment and its consequences. The authors report a case of medically resolved C-ALCL in an 81-year-old man presented with well-defined nodular lesions on the forehead.