Korean Journal of Veterinary Service (한국동물위생학회지)

The Korean Society of Veterinary Service (한국동물위생학회)
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Cutaneous epitheliotropic T-cell lymphoma with Sézary syndrome in a dog

  • Lee, Song in (College of Veterinary Medicine, Chungnam National University) ;
  • Lee, Han Joon (College of Veterinary Medicine, Chungnam National University) ;
  • Seo, Kyoungwon (College of Veterinary Medicine, Seoul National University) ;
  • Song, Kunho (College of Veterinary Medicine, Chungnam National University)
  • Received : 2021.12.08
  • Accepted : 2021.12.24
  • Published : 2021.12.30
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Abstract

A 12-year-old, spayed female, Toy-poodle dog presented in progressive, pruritic carpal mass and mandibular papule. The skin lesions and enlarged superficial lymph nodes were surgically removed. According to histopathology and immunohistochemistry, the patient diagnosed as cutaneous epitheliotropic T-cell lymphoma with lymph node metastasis. Chemotherapy with L-asparaginase, lomustine and prednisolone was initiated. The patient deteriorated despite treatment and was admitted to the hospital. Blood tests revealed significant leukocytosis. Circulating large lymphocytes with convoluted and cerebriform nuclei seen in peripheral blood led to presumption of Sézary cells. Thus, considering skin, lymph nodes and blood involvement, Sézary syndrome was diagnosed.

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References

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