• Title/Summary/Keyword: Systemic effect

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A Clinical study of systemic psoriasis with Su-Gi therapy (전신성 건선 환자에 수기치료를 병행한 치험 1례)

  • Kim, Ji Hee;Kim, Bo Kyun;Bae, Jae Ryong;Han, Won Ju;Ahn, Hun Mo
    • Journal of Korean Medical Ki-Gong Academy
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    • v.15 no.1
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    • pp.71-88
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    • 2015
  • Objects : The purpose of this case study is to report the effect of Su-Gi therapy with Oriental medical treatments on systemic psoriasis. Methods : The subject is a patient with systemic psoriasis. This patient was treated with Oriental medical treatments and Su-Gi therapy. The improvement of the skin condition is observed by Psoriasis Area and Severity Index (PASI) score. Results : After the treatment, the symptoms of psoriasis were relieved. PASI score of this patient went down from 39.6 to 12.5. Conclusions : This study showed that Su-Gi therapy added with Oriental medical treatment can be an effective choice for systemic psoriasis.

Time Course Changes in Hepatic Fat Accumulation in High Fat Diet-fed C57BL/6 Mice: Comparison Analysis to the Markers of Systemic Insulin Resistance (고지방식이 섭취 마우스에서 간 중성지방 축적의 시간에 따른 변화: 인슐린저항성 지표들과의 상관관계 분석)

  • Bae, Eun Ju
    • YAKHAK HOEJI
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    • v.56 no.6
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    • pp.364-365
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    • 2012
  • Liver is the major organ to regulate the systemic glucose homeostasis and insulin resistance. Excess energy intake leads to triglyceride accumulation in adipose tissue first and subsequent accumulation in liver, resulting in obesity and type 2 diabetes. The representative pathological animal model for obesity associated insulin resistance is a high fat diet (HFD) fed mice model. Given the essential role of liver fat accumulation in developing systemic insulin resistance in obesity, I measured the liver triglyceride contents in HFD fed mice as a function of time. As such, in this report, I show the cause and effect relationship with regard to time during a HFD feeding between a variety of factors that are related to systemic insulin resistance including glucose intolerance, plasma insulin level and inflammatory gene expression in liver and adipose tissue.

Activity and control effects of insecticides to American serpentine leafminer, Liriomyza trifolii(Diptera: Agromyzidae) (아메리카잎굴파리 (Liriomyza trifolii)에 대한 살충활성과 방제효과)

  • Kim, Gil-Hah;Lee, Young-Su;Park, Sun-Young;Park, Yong-Seong;Kim, Jeong-Wha
    • The Korean Journal of Pesticide Science
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    • v.5 no.1
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    • pp.46-54
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    • 2001
  • These studies were carried out to investigate the toxicities of 33 registered insecticide to the American serpentine leafminer, Liriomyza trifolii. Insecticidal activities were evaluated by testing systemic action and residual effect in the laboratory, and control efficacy and phytotoxicity in the greenhouse. All insecticides used in this study did not effect on the egg of L. trifolii, although spinosad showed 70% of egg-hatch suppression. For L. trifolii larvae ($2{\sim}3$ instar), the insecticides with over 95% of insecticidal activity were abamectin, cartap, cyromazine, emamectin benzoate, diflubenzuron + chlorpyrifos. The Insecticide what showed over 90% of insecticidal activity or neonate larvae were abamectin, cartap, emamectin benzoate, diflubenzuron + chlorpyrifos and milbemectin. Only cartap + buprofezin showed over 95% insecticidal activity against L. trifolii pupae. Almost insecticides used in this study little or not effected on the adult of L. trifolii. Emamectin benzoate and milbemectin showed moderate foliar systemic effects on eggs of L. trifolii (53.3, 47.9%, respectively). However, other insecticides showed little systemic effect. For larvae and adults, all insecticides showed low systemic effects. Insecticides with over 90% residual effect for 10 days were abamectin, emamectin benzoate and milbemectin (91.4, 90.4, 91.9%, respectively). In the control efficacy test on L. trifolii 90% of control values were obtained at 14th day after treatment of the insecticides including abamectin, cyromazine, emamectin benzoate and milbemectin. Cartap and cartap + buprofezin showed slight phytotoxicity on kidney bean leaf, however, other insecticides showed no phytotoxic effects. These results indicate that abamectin, emamectin benzoate and milbemectin can be used for tile control of L. trifolii in field.

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The Effect of Uncertainty and Fatigue Perceived by Patients with Systemic Lupus Erythematosus on Resilience (루푸스 환자가 지각하는 불확실성과 피로가 극복력에 미치는 영향)

  • Cho, OK-Hee;Lim, Jong-Mi
    • Journal of Digital Convergence
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    • v.19 no.11
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    • pp.615-623
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    • 2021
  • The purpose of this study was to identify the factors influencing resilience of patients with systemic lupus erythematosus. The subject(N=118) was a systemic lupus erythematosus patient who visited the E hospital in D city. The collected data were analyzed by descriptive statistics, t-tset, ANOVA, pearson correlation, and multiple regression. As a result of the study, impact domain of uncertainty, fatigue, self-management domain of uncertainty, trust in doctors domain of uncertainty significant effects on resilience. Based on this study, in order to improve the resilience of patients with systemic lupus erythematosus, a multifaceted approach is needed to reduce the uncertainty perceived by the patient and control fatigue. In addition, it is required to develop an effective nursing intervention program to enhance resilience reflecting influencing factors.

Study on the Anti-allergic Effect of Armeniacae Semen Herbal Acupuncture Solution (행인약침(杏仁藥鍼)이 항알레르기에 미치는 영향)

  • Kim, Yu-Seung;Song, Choon-Ho
    • Korean Journal of Acupuncture
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    • v.24 no.4
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    • pp.151-162
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    • 2007
  • Objectives : The purpose of this study was to examine the anti-allergic effect in vivo, and to observe single toxicity in mice of Armeniacae Semen herbal acupuncture solution (ASHA). Methods : We investigated anti DNP IgE-mediated passive cutaneous anaphylaxis in rodents and compound 48/80-induced active systemic anaphylatic shock in mice after treatment at both BL13 with ASHA of 25 ${\mu}{\ell}$(mice) or 50 ${\mu}{\ell}$(rats) 3 times for 5 days. To ascertain safety and toxicity of ASHA, we examined single toxicity test. In single test, three groups were treated with different dosages of ASHA (ASHA250, ASHA500 and ASHA1000) according to on Korean Food and Drug Administration, respectively. We observed attentively motality, abnormal clinical sign, body weight change, and organ weight of mice after ASHA treatment. Results : ASHA inhibited passive cutaneous anaphylaxis and active systemic anaphylatic shock by oral administration. During toxicity experiment period, there was no difference in body weight change, and organ weight among different dose groups. Death were not found in single test i.p. group. (ASHA250, ASHA500 and ASHA1000). Several individuals of single test i.p. group were observed yellow brown discharge around anus in early period after administration. Conclusions : These results indicate that ASHA have inhibition effects on passive cutaneous anaphylaxis and active systemic anaphylatic shock, and suggest that has some toxicity in high dosage.

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Effect of Saururus chinensis (Lour.) Baill. Aquacupuncture on Anaphlylaxis in Mice (삼백초약침액(三白草藥鍼液)이 아나필락시스에 미치는 영향)

  • Choi, Kyu-Jung;Lee, So-Young;Kang, Kyung-Hwa;Lee, Yong-Tae;Song, Choon-Ho
    • Korean Journal of Acupuncture
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    • v.21 no.3
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    • pp.97-104
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    • 2004
  • Objective We investigated the effect of Saururus chinensis (Lour.) Baill. aquacupuncture (SCB) on anaphylaxis in mice. Methods : We conformed compound 48/80-induced mesenteric mast cell degranulation, active systemic anaphylatic shock and histamine release. Also observed acetic acid-induced vascular permeability and anti-dinitrophenyl (DNP) IgE-mediated passive cutaneous anaphylaxis. Results : SCB inhibited mesenteric mast cell degranulation and active systemic anaphylatic shock induced by compound 48/80 dose-dependently. When SCB was pretreated by intra-peritoneal injection, the serum histamine levels were reduced. SCB also significantly inhibited acetic acid-induced vascular permeability. In addition, SCB showed a significant inhibitory effect on anti-dinitrophenyl (DNP) IgE-mediated passive cutaneous anaphylaxis. Conclusion : These results indicated that SCB inhibits anaphylatic reaction.

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A Clinical Report of Systemic Lupus Erythematosus (전신성 홍반성 낭창(SLE) 환자 1례 증례보고)

  • Jeon, Yeong-Seon;Lee, Eun-Kyu;Kim, Soo-Hyeon;Choi, Yoo-Jin;Park, Kyeong-Mi;Yang, Seung-Jeong;Cho, Seong-Hee
    • The Journal of Korean Obstetrics and Gynecology
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    • v.31 no.4
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    • pp.179-187
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    • 2018
  • Objectives: The purpose of this study is to report the effect of Korean medicine treatments on a systemic lupus erythematosus (SLE). Methods: We treated 1 case of systemic lupus erythematosus patient with Korean herbal medicine, acupuncture, moxibustion and pharmaco-acupuncture. Patient is a 44-year-old woman, who suffered from general body weakness, arthralgia and foamy urine. She was treated with Samilshinki-hwan-gami and Oryeong-san-gami. Patient is taken acupuncture at GV20, CV12, LI4, LR3, ST36, BL23, BL25 and moxibustion at CV4. We injected pharmaco-acupuncture at BL23, BL25. Results: After treatments the patient recovered from foamy urine, reduced general body weakness, arthralgia. Conclusions: This study suggests that Korean medicine treatments have significant effect on reducing symptoms of systemic lupus erythematosus.

Impact of Depression on Medication Adherence of Patients with Systemic Lupus Erythematosus: Focusing on Mediating Effect of Self-Efficacy and Belief about Medication (전신성 홍반성 루푸스 환자의 우울이 복약순응도에 미치는 영향: 자기효능감과 약물에 대한 신념의 매개 효과를 중심으로)

  • Lee, Su Jin;Ju, Hyeon Ok
    • Journal of Korean Clinical Nursing Research
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    • v.25 no.2
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    • pp.170-178
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    • 2019
  • Purpose: The purpose of this study was to determine the mediating effects of self-efficacy and the belief about medication on the association between depression and medication adherence in patients with systemic lupus erythematosus. Methods: 128 patients aged ${\geq}19years$, who were regular outpatients or admitted patients diagnosed with systemic lupus erythematosus at a tertiary hospital in B city, participated in this study. Data were collected by using a self-administered questionnaire. Testing of mediating effects was analyzed by a parallel redundant mediated model using the PROCESS macro for SPSS version 3.3. Results: They scored an average of $16.71{\pm}11.13$ for depression, $694.14{\pm}170.68$ for self-efficacy, $3.05{\pm}4.60$ for the belief about medication, and $90.14{\pm}15.37$ for medication adherence. The direct effect of depression on medication adherence was not statistically significant, but the indirect effects of depression mediated with self-efficacy and belief about medication were statistically significant. Conclusion: It is necessary to develop and apply a nursing intervention program that can not only relieve depression but also promote self-efficacy and the belief about medication with the objective of improving medication adherence among patients with systemic lupus erythematosus.

Chemical Control Effect Against Spot Clothing Wax Cicada, Lycorma delicatula (Hemiptera: Fulgoridae) Nymphs and Adults (꽃매미(Lycorma delicatula) 약충과 성충에 대한 약제방제 효과)

  • Kim, Sun-Kook;Lee, Gi-Yeul;Shin, Yon-Ho;Kim, Gil-Bah
    • The Korean Journal of Pesticide Science
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    • v.14 no.4
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    • pp.440-445
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    • 2010
  • This study was carried out to investigate the toxicities of five registered insecticides to the Lycorma delicatula nymphs and adults. Insecticidal activities were evaluated by testing systemic and residual effects in the laboratory, and control efficacy in the vineyard. For the 3rd nymphal instars and adults, etofenprox+diazinon, chlorpyrifos, etofenprox, dinotefuran and imidacloprid showed perfect insecticidal activity. The systemic effects of dinotefuran and etofenprox+diazinon on grape roots at half concentration were showed the adult mortality of 82.2% and 84.4%, respectively. Chlorpyrifos at recommended concentration was showed mortality of 86.0%. The leaf systemic effects at recommended and half concentrations of all insecticides except dinotefuran were lower than 65% but the mortality at double concentration of chlorpyrifos, dinotefuran, etofenprox were more than 82%. The residual effect between etofenprox+diazinon and dinotefuran at recommended and double concentrations were 100% at 14 days after treatment, the other insecticides have low efficacy. All the four insecticides showed 87% control value on nymphs in the field test and adults appeared more than 96% control value st and adinotefuran, etofenprox+diazinon, however, the other insecticides decreased to 59.1 % and 61.2%. Therefore, dinotefuran and etofenprox+diazinon showing high systemic effects to roots and long residual effects to leafs have high control efficacies.

Enhanced mucosal and systemic immune responses by mucosally administered hepatitis B surface antigen: effects of vaccine delivery vehicles and adjuvants

  • Park, Jeong-Sook;Kim, Chong-Kook
    • Proceedings of the PSK Conference
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    • 2003.04a
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    • pp.121-121
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    • 2003
  • The purpose of this study is to investigate the effect of mucosal vaccine delivery vehicles and adjuvants on the local and systemic antibody responses following mucosal immunization of mice with hepatitis B surface antigen (HBsAg). Mice were immunized on days 0 and 21 by administration of hepatitis B surface antigen B (HBsAg) into the vagina. HBsAg was delivered in saline or poloxamer(Pol)-based vehicle containing mucoadhesive polycarbophil (PC). (omitted)

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