• 대한한의학회지
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• 제45권1호
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• pp.45-64
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• 2024

Objectives: This study is purposed to investigate the effect and safety of laser therapy for stroke patients by systematic review and meta-analysis of the randomized controlled trials (RCTs). Methods: RCTs on the treatment of laser therapy for stroke patients were selected among the literature published from January 2000 to June 2022 in twelve domestic and foreign databases. The quality of the literature was evaluated using the Cochrane's Risk of Bias tool and RevMan 5.4 was used for the synthesis of results. Results: Total 2,598 patients with stroke were finally selected from 18 RCTs. Meta-analysis showed that laser therapy was effective in significantly improving activities of daily living (MBI), motor function (effective rate), upper motor function (FMA-UE), shoulder pain related factors (CGRP, ET-1, BK). Overall, the risk of bias was uncertain or low in the quality assessment of the literature. Conclusions: Although it is unclear that laser therapy is more effective than sham laser, laser therapy might be more effective in improving symptoms than conventional rehabilitation alone. Furthermore, no serious adverse events were founded in laser therapy studies. However, the quality of the selected literature was generally low. Therefore, further studies with high methodological quality on laser therapy for stroke patients would be required in the future.

• 대한한방내과학회지
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• 제43권4호
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• pp.559-566
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• 2022

서론: 본 체계적 문헌 고찰의 프로토콜 논문은 간암의 한약 치료에 대한 효과와 안전성의 근거를 제시하는 것을 목표로 한다. 방법: 본 체계적 문헌 고찰은 간암에 한약 치료에 대한 무작위 대조 임상시험을 포함할 것이다. 오직 무작위 대조 임상시험 유형의 임상 연구만 포함할 것이다. 시험군의 한약 치료는 한약을 사용한 모든 제형을 포함할 것이며, 대조군은 다른 치료, 플라시보 치료, 서양의학적 치료 등을 포함할 것이다. 다음 11개의 데이터베이스를 활용하여 검색할 것이다: the Cochrane Database of Systematic Reviews, MEDLINE, EMBASE, AMED, CINAHL, Chinese database(CNKI), 그리고 다섯 개의 한국데이터베이스(OASIS, DBpia, RISS, KISS, and NDSL). 연구의 선정, 데이터 추출 및 분석 등의 업무는 3명의 연구자가 독립적으로 수행할 것이다. 비뚤림 위험 평가를 포함한 연구의 질적 평가는 Cochrane risk-of-bias assessment tool을 사용할 것이다. 결과: 본 간암에 대한 한약 치료의 체계적 문헌 고찰은 최신의 근거를 요약적이고 분석적으로 제공할 것이다. 결론: 간암의 한약 치료에 대한 효과와 안전성의 근거를 제시할 것이며, 이는 종양학이나 한의학과 보완·대체의료 분야의 종사자들에게 유용한 정보를 제공할 것이다.

• 한국전자거래학회지
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• 제25권4호
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• pp.125-141
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• 2020

최근의 연구들에서는 투자자들의 관심이나 감정이 주식 거래행태와 주가 변동에 미치는 영향에 대한 분석들이 증가하고 있다. 본 연구에서는 투자자들의 관심과 감정을 측정하기 위해 한국의 네이버 검색지수를 이용하여, 포털 검색량과 검색의 변동성이 주가동조성 및 총위험, 체계적 위험에 미치는 영향을 분석하였다. 먼저 평균적인 검색량이 증가할수록 주가동조성은 증가하는 반면, 검색의 변동성은 주가동조성을 감소시키는 것을 관찰하였다. 다음으로 평균 검색량과 검색의 변동성은 모두 주식의 총위험과 체계적 위험을 증가시키는 것으로 나타났다. 이러한 결과는 주가를 변동시키는 사건이 발생할 경우에만 개인투자자들의 검색이 증가하기 때문인 것으로 해석된다. 이러한 결과는 포트폴리오 분석, 고정효과 회귀분석 및 동적 패널 모형에서 일관되게 관찰된다.

• 한국환경보건학회지
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• 제40권3호
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• pp.187-203
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• 2014

Objectives: As the demand to deal with pathogens in domestic research institutions has expanded and biological accidents have increased, the need for systematic biosafety management in infectious disease laboratories has grown. According to international standards, risk assessment (RA) is required for biosafety management. However, RA criteria have not been clearly established in Korea, so to this end I have attempted to determine RA criteria meeting international levels Methods: In order to provide RA criteria for application, I analyzed the RA criteria in use in the U.S., Europe and at international organizations. In order to ensure the public nature of the RA criteria, I constructed the research model through modified management consulting methodology reflecting the model of Radnor and O'Mahoney. Results: According to the results of the study, existing laboratory biosafety regulations were comparable to domestic laboratory safety laws. Existing laboratory biosafety standards that are designed around risk factors were found to be insufficient. An RA case to be carried out in infectious disease laboratories at the National Institute of Health of KCDC was identified. Conclusion: To establish a systematic risk management system meeting international standards, it was necessary first to harmonize the systems of national and international standards. In addition, in order to provide specific biosafety management on-site, I recognized a need for methodology and planning strategies to discover biosafety management so that it can be carried out as required through the RA of individual laboratories.

• Korean Journal of Radiology
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• 제22권10호
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• pp.1730-1741
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• 2021

Objective: Although thermal ablation is effective in treating low-risk papillary thyroid microcarcinomas (PTMCs), comparison of treatment outcomes between thermal ablation and surgery has not yet been systematically evaluated. This study aimed to compare the efficacy and safety of thermal ablation and surgery for the treatment of low-risk PTMCs. Materials and Methods: Ovid-MEDLINE and EMBASE databases were searched for studies reporting comparisons of treatment results between thermal ablation and surgery for patients with low-risk PTMC published up to April 6, 2020. The analysis evaluated the efficacy (local tumor recurrence, occurrence of new tumor, metastasis, and rescue surgery) and safety (complication rate) of thermal ablation and surgery. Results: This systematic review included four studies with a total of 339 PTMCs in 339 patients who underwent thermal ablation and 320 PTMCs in 314 patients who underwent surgery. There was no local tumor recurrence or distant metastasis in either group. There was no significant difference in the pooled proportion of lymph node metastasis (2.6% with thermal ablation vs. 3.3% with surgery, p = 0.65), occurrence of new tumors (1.4% with thermal ablation vs. 1.3% with surgery, p = 0.85), or rescue surgery (2.6% with thermal ablation vs. 1.6% with surgery, p = 0.62). However, the pooled complication rate was significantly higher in the surgery group than in the ablation group (3.3% with thermal ablation vs. 7.8% with surgery, p = 0.03). Conclusion: Both thermal ablation and surgery are effective and safe options for the management of low-risk PTMCs, with thermal ablation achieving a lower complication rate. Therefore, thermal ablation may be considered as an alternative treatment option for low-risk PTMC in patients who refuse surgery and active surveillance or are ineligible for surgery.

• 대한안전경영과학회지
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• 제11권4호
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• pp.247-253
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• 2009

The object of this paper is established for a paradigm for the organization. Although concerns on management get increased in these days, there is no general and systematic framework for a unified sector. Therefore this study proposes the new general and systematic framework for managing in organization, through applying Service-Engineering model. The new framework of this study provides the general sector of organization model, the method of analyzing BSC and RMS, and system model for Risk Management. Furthermore, this study suggests the practical ways of developing a paradigm.

• Safety and Health at Work
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• 제8권3호
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• pp.246-249
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• 2017

Health-care workers are at risk of exposure to occupational infections with subsequent risk of contracting diseases, disability, and even death. A systematic collection of occupational disease data is useful for monitoring current trends in work situations and disease exposures; however, these data are usually limited due to under-reporting. The objective of this study was to review literature related to knowledge, risk perceptions, and practices regarding occupational exposures to infectious diseases in Malaysian health-care settings, in particular regarding blood-borne infections, universal precautions, use of personal protective equipment, and clinical waste management. The data are useful for determining improvements in knowledge and risk perceptions among health-care workers with developments of health policies and essential interventions for prevention and control of occupational diseases.

• 시스템엔지니어링학술지
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• 제7권1호
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• pp.43-51
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• 2011

SE generally defines approaching ways of conducting identification, verification and integration of an optimized product and process solution to meet customer's needs by leveraging organizational competency in engineering and management. To successfully develop a new product under mass production contract, it is important to efficiently carry out the program by ensuring that three major competencies are secured; core technology, system integration, and program management. For successful implementation of tasks in the three areas, systematic execution is called for, which requires identifying risk factors in advance. In particular, comprehensive risk management role and responsibility is required for program management. Success of a development program is determined by complex elements of human resources, organization culture, and overall competency of an organization in technology and program management, including capability of the program manager. In this paper, a risk management solution is suggested to lead a program to success with a more efficient way through actual risk management by the concept of SE around the above three areas.

• 한국신뢰성학회지:신뢰성응용연구
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• 제10권1호
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• pp.73-91
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• 2010

All activities relate to railway traffic involve risk and that these arise from a combination of the nature of operating activities. Proper management system is required to provide the organizational capability to reveal, analyse and address these weaknesses over time and in reasonably practicable ways, which will determine the rate at which risks can be further reduced. This paper presents a systematic risk analysis approach to safety planning and decision making, informed by a range of risk assessment techniques. An railway organization's safety management system is also presented that shows the approaches taken to minimize the external risks, and identify the shared risks and explain how they will be controlled through collaboration with others.

• 재무관리논총
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• 제3권1호
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• pp.179-211
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• 1996

This study examines whether trading mechanisms or market microstructures of markets have an effect on the integration issue of the international equity market. If the international equity market is integrated, identical stocks listed on different international stock exchanges should have the same rates of return, the same characteristics of stock price behavior and similar distributions of return. If different market microstructures, or trading mechanisms cause differences in characteristics of stock price behavior, those can lead to different rates of return because of different liquidity risk for the same stocks between markets. This study proposes international asset pricing with liquidity risk related to trading mechanisms. Systematic risk by itself cannot predict the sign of expected rate of return difference for the same stocks between international markets. Liquidity risk factors related to market microstructure provide explanations for the sign of rate of return differences between markets, However, liquidity risk factors related to market microstructure do not have a significant effect on the rate of return differences and sensitivity of return differences between markets, Trading mechanisms or market microstructures might not have a significant effect on the interpretation of the international equity market integration studies, if trading volume or other factors are controlled.