• 한국지반환경공학회 논문집
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• 제23권5호
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• pp.25-32
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• 2022

최근 우리나라에 리히터 규모 5.0 이상의 지진발생 2건과 규모가 낮은 지진발생이 많아짐에 따라 지진피해가 늘어나면서 내진설계에 대한 많은 연구와 관심이 높아지고 있으며, 그 중 최근 발생한 포항지진으로 인해 항만시설물에 대한 내진설계에도 관심이 높아졌다. 본 연구에서는 1g 진동대시험을 통하여 항만구조물 중 직립식, 경사식 방파제에 대한 지진 시 발생하는 동적거동에 대해서 실험 및 분석을 하였다. 이를 위해 사상법칙을 적용한 모델에 장주기(Hachinohe), 단주기(Ofunato), 인공지진파 총 세가지 지진파를 적용하고, 연약지반의 DCM 공법 보강 여부를 고려하여 실험하였다. 진동대시험결과를 기초로 지진 시 DCM 공법 보강 여부에 따라 직립식과 경사식 방파제의 동적거동에 대하여 가속도 및 수평·수직 변위를 분석하였다. 검토 결과 직립식 및 경사식 방파제 동적거동은 DCM 공법 보강을 한 경우에 지지력 및 강성이 높아짐에 따라 가속도의 증폭이 억제되는 경향을 나타내었다.

• Coupled systems mechanics
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• 제11권6호
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• pp.557-586
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• 2022

In spite of extensive testing of the individual shear wall and the coupling beam (CB), numerical and experimental researches on the seismic behavior of CSW are insufficient. As far as we know, no previous research has investigated the affectations of position of CB regarding to the slab level (SL). So, the investigation aims to enhance an overarching framework to examine the consequence of connection positions between CB and SL. And, three cases have been created. One is composed of the floor slab (FS) at the top of the CB (FSTCB); the second is created with the FS within the panel depth (FSWCB), and the third is employed with the FS at the bottom of the CB (FSLCB). And, FEA is used to demonstrate the consequences of various CB positions with regard to the SL. Furthermore, the main measurements of structure response that have been investigated are deformation, shear, and moment in a coupled beam. Additionally, wall elements are used to simulate CB. In addition, ABAQUS software was used to figure out the strain distribution, shear stress for four stories to further understand the implications of slab position cases on the coupled beam rigidity. Overall, the findings show that the position of the rigid linkage among the CB and the FS can affect the behavior of the structures under seismic loads. For all structural heights (4, 8, 12 stories), the straining actions in FSWCB and FSLCB were less than those in FSTCB. And, the increases in displacement time history response for FSWCB are around 16.1-81.8%, 31.4-34.7%, and 17.5% of FSTCB.

• Biomolecules & Therapeutics
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• 제31권3호
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• pp.264-275
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• 2023

Parkinson's disease (PD) is a common neurodegenerative disorder characterized by tremors, bradykinesia, and rigidity. PD is caused by loss of dopaminergic (DA) neurons in the midbrain substantia nigra (SN) and therefore, replenishment of DA neurons via stem cell-based therapy is a potential treatment option. Astrocytes are the most abundant non-neuronal cells in the central nervous system and are promising candidates for reprogramming into neuronal cells because they share a common origin with neurons. The ability of neural progenitor cells (NPCs) to proliferate and differentiate may overcome the limitations of the reduced viability and function of transplanted cells after cell replacement therapy. Achaete-scute complex homolog-like 1 (Ascl1) is a well-known neuronal-specific factor that induces various cell types such as human and mouse astrocytes and fibroblasts to differentiate into neurons. Nurr1 is involved in the differentiation and maintenance of DA neurons, and decreased Nurr1 expression is known to be a major risk factor for PD. Previous studies have shown that direct conversion of astrocytes into DA neurons and NPCs can be induced by overexpression of Ascl1 and Nurr1 and additional transcription factors genes such as superoxide dismutase 1 and SRY-box 2. Here, we demonstrate that astrocytes isolated from the ventral midbrain, the origin of SN DA neurons, can be effectively converted into DA neurons and NPCs with enhanced viability. In addition, when these NPCs are inducted to differentiate, they exhibit key characteristics of DA neurons. Thus, direct conversion of midbrain astrocytes is a possible cell therapy strategy to treat neurodegenerative diseases.

• Smart Structures and Systems
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• 제32권3호
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• pp.153-166
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• 2023

Health monitoring of civil infrastructures, in particular, old bridges that are still in service, has become more than necessary, given the risk that a possible degradation or failure of these infrastructures can induce on the safety of users in addition to the resulting commercial and economic impact. Bridge integrity assessment has attracted significant research efforts over the past forty years with the aim of developing new damage identification methods applicable to real structures. The bridge of Ouled Mimoun (Tlemcen, Algeria) is one of the oldest railway structure in the country. It was built in 1889. This bridge, which is too low with respect to the level of the road, has suffered multiple shocks from various machines that caused considerable damage to its central part. The present work aims to analyze the stability of this bridge by identifying damages and evaluating the damage rate in different parts of the structure on the basis of a finite element model. The applied method is based on an inverse analysis of the normal stress responses that were calculated from the corresponding recorded strains, during the passage of a real train, by means of a set of strain gauges placed on certain elements of the bridge. The results obtained from the inverse analysis made it possible to successfully locate areas that were really damaged and to estimate the damage rate. These results were also used to detect an excessive rigidity in certain elements due to the presence of plates, which were neglected in the numerical reference model. In the case of the continuous bridge monitoring, this developed method will be a very powerful tool as a smart health monitoring system, allowing engineers to take in time decisions in the event of bridge damage.

• Geomechanics and Engineering
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• 제37권5호
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• pp.511-525
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• 2024

Micropiled raft has been used to support the existing and new structures or to provide the seismic reinforcement of foundation systems. Recently, research on micropile or micropiled raft has been actively conducted as the usage of micropile has increased, and the reinforcement effect of pile for the raft, the pile installation methods, and methods for calculating the bearing capacity of micropiled raft have been proposed. In addition, existing research results show that the behavior of this foundation system is different depending on the pile conditions and can be greatly influenced by the characteristics of the upper or lower ground depending on the conditions of pile. In other words, considering that the micropile is a friction pile, it can be predicted that the reinforcing effect of micropile for the raft and the bearing capacity of micropiled raft may depend on the cohesion of upper soil layer depending on the pile conditions. However, existing studies have limitations in that they were conducted without taking this into account. However, existing studies have limitations as they have been conducted without considering these characteristics. Accordingly, this study investigated the reinforcing effect of micropile and the bearing characteristics of micropiled raft by varying the cohesion of upper soil layer and the stiffness of pile which affect the behavior of micropiled raft. In this results, the reinforcing effect of micropile on the raft also increased as the cohesion of soil layer increased, but the reinforcing effect of pile was more effective in ground conditions with decreased the cohesion. In addition, the relationship between the axial stiffness of micropile and the bearing capacity of micropiled raft was found to be a logarithmic linear relationship. It was found that the reinforcing effect of micropile can increase the bearing capacity of raft by 1.33~ 3.72 times depending on the cohesion of soil layer and the rigidity of pile.

• 한국산학기술학회논문지
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• 제17권8호
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• pp.200-207
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• 2016

자동차 시트는 운행 중에 운전자와 항상 같이 움직이는 핵심부품으로 다양한 기능과 편의장치를 포함하는 제품의 개발이 활발히 진행되고 있는 추세이다. 본 논문에서는 경량화 소재를 적용한 경량형 시트 쿠션 익스텐션 모듈 개발을 위해 구조강도 해석평가, 수직강도 시험평가, 그리고 내구강도 시험평가를 수행하였다. 구조해석 결과, 수직 하중 부하 시 변형량의 최대값은 4.98mm로 상판의 최 전단에서 발생하였다. 최대응력은 약 105MPa로 익스텐션 모듈의 상판과 하판이 접촉하는 부분에서 발생함을 확인하였다. 수직강도 시험평가 결과, 수직 하중 부하 시 변형량의 최대값은 5.31mm로 구조해석 결과 대비 약 6.45% 정도의 차이가 나타났으며 수직강도 및 20,000회 내구강도 시험 후 제품에는 작동 시 유해한 변형 및 파괴가 없음을 확인함으로써 구조 안전성을 검증하였다. 본 연구에서는 엔지니어링 플라스틱 소재를 적용하여 기존 양산품 대비 약 30%의 중량절감을 확인하였고 정적 강도, 내구 강도 시험 후 파손이 되지 않으므로 승객의 안정성과 제품의 충분한 강도와 강성을 검증하였다. 본 논문에서 수행한 연구결과는 환경/연비규제 강화에 대응 가능 및 운전자의 피로도 감소로 인한 사고 예방 효과 증대, 고급 승용차뿐만 아니라 소형 및 경차종, 상용차, 특장차 등에 확대 적용, 친환경, 경량화 소재 적용기술을 활용한 타 산업분야 및 부품에 확대 적용이 예상된다.

• 한국임상수의학회지
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• 제19권2호
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• pp.174-185
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• 2002

We investigated the effects of yohimbine and atipamezole in dogs anesthetized with xylazine-ketamine combination on electroencephalography (EEG) . Experiment groups were divided into three according to antagonists . Saline (1 ml) was used as an antagonist in group C, yohimbine (0.1 mg/kg) in group Y and atipamezole (50 ug/kg) in group A. Each group consisted of 5 dogs. Glycopyrrolate was injected 15 minutes prior to xylazine injection. Xylazine (1.1 mg/kg, IM) and ketamime (10 mg/kg, IV) were injected with the interval of 10 minutes. After 15 minutes, antagonists were administered intravenously. For EEG measurements, a recording electrode was positioned at Cz, which was applied to International 10-20 system. Heart rates, body temperature, respiratory rates, arterial blood pressure, $PaO_2$$PaCO_2$$PaCO_2$ at S4 in group Y was significantly decreased(p<0.05). Changes of electrolytes were not significant, except value of $Cl^-$ at S3 in group A. Mean head-up time (the time dogs showing head-up movement after antagonist injection, minutes) was $38.23^{\circ}$ae6.46 in group C, 2.54 $\pm$ 0.93 in group Y and 2.12$\pm$ 1.32 in group A. Mean sternal recumbent time (the time dogs showing sternal recumbency after antagonist injection, minutes) was 45.93$\pm$ 10.27 in group C, 11.91 $\pm$ 7.19 in group Y and 9.88$\pm$ 3.38 in group A. Mean walking time (minutes) was 53.49$\pm$ 9.21 in group C, 22.10$\pm$ 11.10 in group Y and 18.48$\pm$ 4.39 in group A. In group Y all dogs showed excitation and muscle rigidity in emergence. In group A, two dogs were also showed excitation and muscle rigidity, but were weaker than those of group Y.

• 대한지리학회지
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• 제28권2호
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• pp.148-162
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• 1993

현대 자본주의 사회가 대량생산체제에서 유연적 전문화 생산체제로 질적인 변화를 겪고 있다는 주장이 사회과학계를 풍미하고 있다. 이 글의 목적은 이러한 柔軟化論者들의 주장을 개관하고 그 문제점을 살피는 데 있다. 유연적 전문화 논의는 개념 자체가 지극히 관념적이고, 상대적일 뿐만 아니라 학자들 간에 용어사용에 대한 의견일치가 이루어지지 안하아 현재 혼란의 와중에 있다. 유연적 생산체제로의 移行은 二分論的인 설명방식의 사용으로 과장된 측면이 많은데, 실제는 선진 자본주의 국가에 있어서도 매우 부분적으로만 진행되고 있는 상태이다. 한국의 경제와 국토공간은 대규모 기업집단과 그들의 중층적 하청조직에 의해 그 골격이 형성되어 있는 관계로 柔軟化論의 한국에의 적용은 많은 注意를 요한다. 현재의 혼란으로부터 벗어나기 위해 가장 우선적으로 해결해야 할 문제점은 용어의 적용대상 및 적용범위를 통일하는 일이다.

• 전기학회논문지
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• 제67권11호
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• pp.1423-1433
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• 2018

Recently, a permanent magnet synchronous motor of middle and small-capacity has high torque, high precision control and acceleration / deceleration characteristics. But existing control has several problems that include unpredictable disturbances and parameter changes in the high accuracy and rigidity control industry or nonlinear dynamic characteristics not considered in the driving part. In addition, in the drive method for the control of low-vibration and high-precision, the process of connecting the permanent magnet synchronous motor and the load may cause the response characteristic of the system to become very unstable, to cause vibration, and to overload the system. In order to solve these problems, various studies such as adaptive control, optimal control, robust control and artificial neural network have been actively conducted. In this paper, an incremental encoder of the permanent magnet synchronous motor is used to detect the position of the rotor. And the position of the detected rotor is used for low vibration and high precision position control. As the controller, we propose augmented state feedback control with a speed observer and first order deadbeat disturbance observer. The augmented state feedback controller performs control that the position of the rotor reaches the reference position quickly and precisely. The addition of the speed observer to this augmented state feedback controller compensates for the drop in speed response characteristics by using the previously calculated speed value for the control. The first order deadbeat disturbance observer performs control to reduce the vibration of the motor by compensating for the vibrating component or disturbance that the mechanism has. Since the deadbeat disturbance observer has a characteristic of being vulnerable to noise, it is supplemented by moving average filter method to reduce the influence of the noise. Thus, the new controller with the first order deadbeat disturbance observer can perform more robustness and precise the position control for the influence of large inertial load and natural frequency. The simulation stability and efficiency has been obtained through C language and Matlab Simulink. In addition, the experiment of actual 2.5[kW] permanent magnet synchronous motor was verified.

• 한국지구물리탐사학회:학술대회논문집
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• 한국지구물리탐사학회 2004년도 정기총회 및 제6최 특별 심포지움
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• pp.25-48
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• 2004

구조물의 시간경과에 따른 변형 및 성능저하 현상은 인위적 요인 및 시간경과에 따른 지반상태의 변화 혹은 지반 변위요인의 누적에 의해 발생한다. 본 연구에서는 경상남도 경주시에 위치한 첨성대를 연구대상으로 설정하였다. 첨성대는 약 1,300여 년 전 건립된 석축구조물로서 지반침하로 약간 기울어져 있으며, 일부 석재 사이의 틈이 벌어져 있는 상태이다. 본질적인 대책수립을 위하여 본 연구에서는 이러한 목적을 위하여 3차원 레이저스캐닝시스템에 의한 (형상)역공학적 연구, 물리탐사에 의한 지반공학적 특성 연구 및 고유진동수 측정에 의한 첨성대의 동적특성 등의 다음과 같은 연구들을 수행하였다. 첫째, 정밀측량에 의한 첨성대의 정밀한 변형량 측정 및 지속적인 변위측정을 위하여 3차원 레이저 스캐닝에 의한 첨성대의 3차원 공간위치정보를 취득하여 형상역공학에 의한 3차원 벡터이미지 형상구현 및 첨성대의 크기, 변위량, 변위방향 등 여러 가지 제원을 구하고자 하였다. 둘째, 다양한 비파괴적 물리탐사 방법들을 적용하여 첨성대 및 주변 지반의 물성분포 및 지반특성을 파악하고자 하였다. 한편, 다양한 물리탐사를 통하여 향후 유사한 조사에 있어서 적절한 물리탐사 방법을 제시하고자 하였다. 셋째, 경주 첨성대의 1/10 모형에 대한 동적특성실험 및 실물에 대한 고유진동수 측정을 통해 첨성대의 구조적 특성을 연구하여 첨성대의 구조특성 및 상태판단 및 동적특성 파악에 의한 내진성능을 판단하고자 하였다.