• 한국대기환경학회지
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• 제19권6호
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• pp.639-646
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• 2003

In this study, we evaluated genotoxicity of heavy metals among particulates with Tradescantia-micronucleus (Trad-MCN) assay in the various working environment. In a synthetic fiber factory and a rubber factory, chromium concentration was higher than any other heavy metals. On the other hand, nickel concentration was the highest in a semi-conductor factory. The difference in genotoxicity among the working environment was statistically significant as Trad-MCN frequencies were 4.07 $\pm$0.35 MCN/100 tetrads (p< 0.01) for the synthetic fiber factory,5.73 $\pm$0.81 MCN/100 tetrads (p< 0.01) for the rubber factory, and 15.60$\pm$2.58 (p< 0.01) (p< 0.001) for the semi -conductor factory. As a result, heavy metals among particulates in the working environment can be considered to have hazardous potential to human health, although they cannot directly induce DNA damage to the workers in the working environments.

• BMB Reports
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• 제45권2호
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• pp.59-70
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• 2012

Carbon catabolite repression (CCR) is a key regulatory system found in most microorganisms that ensures preferential utilization of energy-efficient carbon sources. CCR helps microorganisms obtain a proper balance between their metabolic capacity and the maximum sugar uptake capability. It also constrains the deregulated utilization of a preferred cognate substrate, enabling microorganisms to survive and dominate in natural environments. On the other side of the same coin lies the tenacious bottleneck in microbial production of bioproducts that employs a combination of carbon sources in varied proportion, such as lignocellulose-derived sugar mixtures. Preferential sugar uptake combined with the transcriptional and/or enzymatic exclusion of less preferred sugars turns out one of the major barriers in increasing the yield and productivity of fermentation process. Accumulation of the unused substrate also complicates the downstream processes used to extract the desired product. To overcome this difficulty and to develop tailor-made strains for specific metabolic engineering goals, quantitative and systemic understanding of the molecular interaction map behind CCR is a prerequisite. Here we comparatively review the universal and strain-specific features of CCR circuitry and discuss the recent efforts in developing synthetic cell factories devoid of CCR particularly for lignocellulose-based biorefinery.

• 한국재료학회:학술대회논문집
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• 한국재료학회 2009년도 추계학술발표대회
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• pp.12.1-12.1
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• 2009

Nano-hydroxyapatite (N-HAp)has shown the pivotal role in producing bone-regenerative materials since it has similarity to natural bone minerals in terms of size, morphology, and the composition. Currently, the combination of biopolymers and N-HAp is recognizedas an attractive approach in generating hybrid scaffolds for bone tissueengineering. Surface engineering is an important issue since it determines whether cells can effectively adhere and proliferate on porous scaffolds. We aim to develop a synthetic approach to porous 3D scaffolds by immobilizing N-HAp on pore surfaces. The discrete nano-level anchoring of N-HAp on the scaffold pore surface is achieved using surface-repellent stable colloidal N-HAp with surface phosphate functionality. This rational surface engineering enables surface-anchored N-HAp to express its overall intrinsic bioactivity,since N-HAp is not phase-mixed with the polymers. The porous polymer scaffolds with surface-immobilized N-HAp provide more favorable environments thanconventional bulk phase-mixed polymer/N-HAp scaffolds in terms of cellular interaction and growth. In vitro biological evaluation using alkalinephosphatase activity assay supports that immobilized N-HAp on pore surfaces of polymer scaffolds contributed to the more enhanced in vitro osteogenicpotential. Besides, the scaffolds with surface-exposed N-HAp provide favorable environments for enhanced in vivo bone tissue growth, estimated by characteristic biomarkers of bone formation such as collagen. The results suggest that newly developed hybrid scaffolds with surface-immobilized N-HApmay serve as a useful 3D substrate with pore surfaces featuring excellent bonetissue-regenerative properties. Acknowledgement. This research was supported by a grant (code #: 2009K000430) from 'Center for Nanostructured Materials Technology' under '21st Century Frontier R&D Programs' of the Ministry of Education, Science and Technology, Korea.

• 산업과 과학
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• 제2권3호
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• pp.8-14
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• 2023

대다수의 IoT 기기들은 이미 AIoT를 사용하고 있지만, AI 애플리케이션을 구축하기 위해서는 아직 해결해야 할 문제가 많이 남아 있다. 본 연구에서는 IoT 에지 자원을 보다 효과적으로 분산하기 위해 머신러닝 기반의 IoT 에지 자원 관리 기법을 제안한다, 제안 기법은 머신러닝을 이용하여 IoT 에지 자원 동향을 파악함으로써 IoT 자원의 할당을 지속적으로 개선하며, 최적화된 IoT 자원은 머신러닝 컨볼루션을 활용하여 항상 변화하는 IoT 에지 자원을 안정적으로 유지한다, 제안 기법은 각각의 머신러닝 기반 IoT 에지 자원을 이전 패턴의 자원과 함께 해시값으로 저장함으로써 분산된 AIoT 맥락에서 공격 패턴으로 자원을 효과적으로 검증한다. 실험 결과에서는 IoT Edge 리소스의 무결성을 검증하기 위해서 이질적인 계산 하드웨어가 있는 복잡한 환경에서 잘 동작하는지 세 가지 다른 테스트 시나리오에서 에너지 효율성을 평가하였다.

• 한국수자원학회논문집
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• 제53권11호
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• pp.973-983
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• 2020

최근 인공위성 자료를 기반으로 한 수자원 관측 분야에서는 공간해상도의 한계를 극복하기 위한 방안으로 SAR (Synthetic Aperture Radar) 센서에 대한 관심이 높아지고 있다. 토양수분을 관측하는 기존 위성 자료가 10 km 이상의 공간해상도를 지닌 반면, SAR 센서는 후방산란계수를 10 m 까지 관측할 수 있으므로 공간적인 분포를 보다 세밀하게 분석할 수 있다. 이러한 자료를 활용하기 위해서는 관측된 후방산란계수에 다양한 수문인자 및 환경적 요인이 미치는 영향을 다각적으로 분석하여 토양수분을 산출하는 과정이 필요하다. 본 연구는 토양수분 산정에 주로 적용되고 있는 WCM(Water Cloud Model)과 선형회귀 기법을 국내 5개 지점에 적용함으로써, SAR 영상을 기반으로 토양수분을 산정하고 이를 지점 관측 자료와 비교하여 평가하고자 하였다. WCM의 경우 토양수분의 즉각적인 변화를 관측하기에 용이하나 오차에 대한 보정이 필요한 것으로 판단되며, 선형회귀 방법은 순간적인 토양수분의 변동이 크게 나타나지 않았으나 안정적인 오차 범위를 나타내었다. 또한 토양수분이 후방산란계수에 미치는 영향은 토지피복, 식생의 분포, 식생 내 수분량의 정도에 따라 모델별로 크게 상이한 결과를 나타냄을 알 수 있으며, 기존의 모델을 동일하게 적용하기에는 한계점이 많음을 알 수 있다. 따라서 복잡한 지형적, 수문학적 특성을 가진 한반도에서 SAR 영상을 수자원 분야에 적용하기 위해서는, 추후 각 지점 별 특성에 따른 영향을 다각적으로 분석하는 과정이 필수적이며 한반도에 적합한 토양수분 모델을 구축하기 위한 연구가 수행되어야 할 것으로 판단된다.

• International Journal of Internet, Broadcasting and Communication
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• 제12권4호
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• pp.93-101
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• 2020

Shipyards are potential environments for using IoT services, sensor networks, and delay tolerant networks. Simulations of those services and networks strongly rely on human mobility models. Results obtained with an unrealistic model may not reflect the true performance of applications, protocols, and algorithms in a shipyard. A lot of synthetic models for human movements have been studied but most of them are generic and focus on the daily movements of humans on city scales. Nevertheless, workers in shipyards have unique movement characteristics such as movement speed, pause time, and attractions places. For instance, workers usually move to some places, where they work, and rarely move to other places in the factory. Movement characteristics of workers not only depend on workers but also on tasks, which they do. For instance, workers, who paint ships, have similar movement speed and pause time. Hence, in this paper, human movements in shipyards are studied. We propose a new human mobility model called the human mobility mode in shipyards (MIS). In MIS, workers are classified into multiple types. Movement characteristics of a worker are similar to other workers in the same type. Based on the visiting probability, workers have some places, where they frequently visits, and some places, where they rarely visit. We analyze real mobility traces and studie to achieve human movement characteristics from real traces. The results show that MIS provides a well-match to the movement characteristic from real traces.

• 품질경영학회지
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• 제37권3호
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• pp.65-73
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• 2009

This research analyzes results and efficiency to promote a government enterprise of A Korean public enterprise to use DEA. Especially, we were used analysis efficiency which are one is year-on-year, another is integrated, and the other is vertical analysis. As a results of integrated analysis show that Gyeonggi_2003 Gyeonggi_2004, Gangwon_2004, Chungcheon-Bukdo_2003, Chungcheon-Bukdo_2004, Cholla-Namdo_2005, and Kyongsang-Bukdo_2003 need to improve upon. Year-on-year analysis result that Gyeonggi, Gangwon, and Kyongsang-Bukdo need urgent improvement. Today, many advanced countries approach not only agricultural investment but also synthetic investment because they believe that agriculture contains living space including food control. Therefore, when the government make a strategic plan for the land and water development in the field of agriculture, they should prepare it well including the proper measures to cope with the internal and external environments.

• 한국항공우주학회지
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• 제36권10호
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• pp.947-953
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• 2008

다분야 통합 최적설계(MDO) 프레임워크는 항공우주시스템의 설계에 고려해야 할 다양한 설계 분야의 통합적이고 동시적인 해석 및 설계 최적화를 위한 통합 환경으로 해석자원 및 최적화자원은 물론 CAD 툴과 DBMS 또한 통합해야하며 사용자편의환경을 제공해야한다. 또한 설계하고자 하는 대상 및 개발환경에 따라 프레임워크의 구축방법은 달라질 수 있다. 본 논문에서는 개발환경에 따라 단일 PC기반 프레임워크와 PLinda기반 프레임워크, 그리고 웹서비스 기반 프레임워크로 분류하여 이들을 비교 분석하였다.

• 한국항공우주학회지
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• 제35권12호
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• pp.1121-1128
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• 2007

다분야 통합 최적설계(MDO)는 여러 설계분야가 복잡하게 얽혀서 설계가 진행되어야 하는 항공기나 우주발사체등의 설계에 매우 유용하게 적용되고 MDO 시스템은 다양한 설계 분야의 통합적이고 동시적인 해석 및 설계 최적화를 위한 통합 환경 또는 시스템이다. MDO 시스템은 이기종의 환경에서 분산되어있는 다양한 해석 코드 및 최적화 코드, CAD, DBMS, GUI등의 자원들을 통합하고 효율적으로 사용할 수 있어야하며 협업설계환경을 제공해야한다. 본 논문에서는 웹 서비스 기반의 글로버스 툴킷을 이용해 설계자원들을 통합하고 워크플로우, 에이전트 등의 자동화 기술을 이용해 유기적인 자동실행을 제공하며 웹 유저 인터페이스를 통해 협업설계환경을 제공하는 웹 서비스 기반 MDO 시스템의 구축방안을 제시한다.

• 한국해양공학회지
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• 제34권1호
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• pp.46-54
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• 2020

Oil spill accidents at sea result in a wide range of damages, including the destruction of ocean environments and ecosystems, as well as human illnesses by the generation of harmful gases caused by phase changes in crude oil. When an oil spill occurs, an immediate initial action should be performed to minimize the potential damage. Existing studies have attempted to identify crude oil spillage by calculating the crude oil spill range using synthetic aperture radar (SAR) satellite images. However, SAR cannot capture rapidly evolving events because of its low acquisition frequency. Herein, an algorithm for estimating an oil spill area from an image obtained using a digital camera is proposed. Noise that may occur in the image when it is captured is first eliminated by preprocessing, and then the image is analyzed. After analyzing the characteristics of the digital image, a strategy to binarize an image using the color, saturation, or lightness contained in it is adopted. It is found that the oil spill area can be readily estimated from a digital image, allowing for a faster analysis than any conventional method. The usefulness of the oil spill area measurement was confirmed by applying the developed algorithm to various oil spill images.