Journal of Korean Society for Atmospheric Environment (한국대기환경학회지)

Korean Society for Atmospheric Environment (한국대기환경학회)
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Genotoxicity of Heavy Metals among the Particulates in the Working Environment as Assessed by Tradescantia-Micronucleus (Trad-MCN) Assay

자주달개비 미세핵 분석법을 이용한 작업환경내 총 먼지 중 수용성 추출물의 유전독성 평가

  • 신해식 (한국원자력연구소, 충남대학교 환경공학과) ;
  • 김진규 (한국원자력연구소) ;
  • 이재환 (연세대학교 화학과) ;
  • 황갑성 (충청대학 생명공학부) ;
  • 김균 (한국화학연구원부설안전성평가연구소) ;
  • 이정주 (용인대학교 환경ㆍ생명학부) ;
  • 이진홍 (충남대학교 환경공학과)
  • Published : 2003.12.01
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Abstract

In this study, we evaluated genotoxicity of heavy metals among particulates with Tradescantia-micronucleus (Trad-MCN) assay in the various working environment. In a synthetic fiber factory and a rubber factory, chromium concentration was higher than any other heavy metals. On the other hand, nickel concentration was the highest in a semi-conductor factory. The difference in genotoxicity among the working environment was statistically significant as Trad-MCN frequencies were 4.07 $\pm$0.35 MCN/100 tetrads (p< 0.01) for the synthetic fiber factory,5.73 $\pm$0.81 MCN/100 tetrads (p< 0.01) for the rubber factory, and 15.60$\pm$2.58 (p< 0.01) (p< 0.001) for the semi -conductor factory. As a result, heavy metals among particulates in the working environment can be considered to have hazardous potential to human health, although they cannot directly induce DNA damage to the workers in the working environments.

Keywords

References

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