• 대한공업교육학회지
• /
• v.38 no.2
• /
• pp.176-194
• /
• 2013

In this research, 'Construction Technology and Environment' units in 12 different technology home economics textbooks for 1st~3rd year middle school students under the 2009 Revised Educational Curriculum and the content system of textbooks were analyzed based on Reigeluth's elaboration theory, and the following conclusions were derived. First, each of the 12 different textbooks presented the elaboration process by procedural method and composed the content system. Second, the 'Construction Technology and Environment' unit presented many 'Thought Opening' as the systematization strategy of advance learning ability, and 'Unit Summary' presented at the end of the unit as the use strategy of the summarizer was presented preponderantly. In addition, 'Learning Objective' that represents the degree of achievement of the students after learning the unit was presented most as the use strategy of the synthesizer although there are differences in terms. In all of the textbooks, 'Figure,' 'Table,' 'Diagram', and 'Explanation of Terms' were used, and particularly, in the vitalizer strategy of the cognitive strategy, overwhelmingly greater number of 'Figure's, compared with all other elements, were presented as the vitalizer strategy of cognitive strategy. Finally, 'Compensatory Learning,' and 'In-depth Study' were presented as the learner control strategy in each of the 4 different textbooks, and there was one textbook that presents the term 'Supplement Reinforcement' in which compensatory learning and in-depth learning were integrated. Third, the metaphor utilization strategy among the 7 teaching strategies of the elaboration theory was hardly used in the composition items in units of textbooks.

• Journal of Radiopharmaceuticals and Molecular Probes
• /
• v.1 no.1
• /
• pp.38-45
• /
• 2015

Most tumors are believed to overexpress several receptors, and small peptides targeting these receptors were developed for diagnosis and tumor therapy during past decade. Here we report that fibroadenoma can be visualized by bladder cancer specific peptide. A 9-mer bladder cancer specific peptide, which was discovered from the phage display method, was synthesized by peptide synthesizer, and additional tyrosine was conjugated at the N-terminal for radioiodination (Y-BP). Y-BP was radiolabeled with $^{131/124}I$ using Iodogen tube. The rat treated with N-butyl-N-(4-hydroxybutyl)nitrosamine for 8 weeks was allowed to grow until large size tumor was developed under axilla. The tumor model was microPET imaged sequentially using [$^{18}F$]FDG and radioiodinated $^{124}I-Y-BP$. The tumor was excised and examined by immunostaining studies. Radioiodinated $^{124}I-Y-BP$ was purified using fast protein liquid chromatography (FPLC) in > 90% radiochemical purity. The whole tumor was well visualized by [$^{18}F$]FDG with several intense focal uptake within tumor. The tumor was also clearly seen with $^{124}I-Y-BP$ at 4 h post-injection, and to our surprise the tumor uptake of $^{124}I-Y-BP$ lasted up to three days. The tumor was diagnosed histologically as a fibroadenoma derived from mammary gland. In conclusion, the bladder cancer specific peptide showed the good potential as a new radiotracer for the detection of breast fibroadenoma.

• Journal of the Korean Society for Aeronautical & Space Sciences
• /
• v.39 no.6
• /
• pp.553-558
• /
• 2011

This paper describes the development and test result of S-band Transmitter flight model(FM) of STSAT-3 by satellite research center(SaTReC), KAIST. The communication sub-system of STSAT-3 is consist of two different frequency band channels, S-band for Telemetry & Command and X-band for mission data. S-band Transmitter(STX) functionally made of modulator, frequency synthesizer, power amp and DC/DC converter. The transmission data is modulated by FSK(Frequency Shift Keying) and the interface between spacecraft sub-module and STX is RS-422 standard method. The FM STX is based on modular design. The RF output power of STX is 1.5W(31.7dBm) and BER of STX is under $1{\times}10^{-5}$ which meets the specification respectively. The FM STX is delivered Spacecraft Assembly, Integration and Test(AIT) level through the completion of functional Test and environmental(vibration, thermal vacuum) Test successfully.

• Journal of the Korea Society of Computer and Information
• /
• v.20 no.5
• /
• pp.53-63
• /
• 2015

Singing voice synthesis is the generation of a song using a computer given its lyrics and musical notes. Hidden Markov models (HMM) have been proved to be the models of choice for text to speech synthesis. HMMs have also been used for singing voice synthesis research, however, a huge database is needed for the training of HMMs for singing voice synthesis. And commercially available singing voice synthesis systems which use the piano roll music notation, needs to adopt the easy to read standard music notation which make it suitable for singing learning applications. To overcome this problem, we use a speech database for training context dependent HMMs, to be used for singing voice synthesis. Pitch and duration control methods have been devised to modify the parameters of the HMMs trained on speech, to be used as the synthesis units for the singing voice. This work describes a singing voice synthesis system which uses a MusicXML based music score editor as the front-end interface for entry of the notes and lyrics to be synthesized and a hidden Markov model based text to speech synthesis system as the back-end synthesizer. A perceptual test shows the feasibility of our proposed system.

• The Journal of the Acoustical Society of Korea
• /
• v.15 no.4
• /
• pp.24-31
• /
• 1996

In this paper, we present a speech translation system for hotel reservation, KT_STS(Korea Telecom Speech Translation System). KT-STS is a speech-to-speech translation system which translates a spoken utterance in Korean into one in Japanese. The system has been designed around the task of hotel reservation(dialogues between a Korean customer and a hotel reservation de나 in Japan). It consists of a Korean speech recognition system, a Korean-to-Japanese machine translation system and a korean speech synthesis system. The Korean speech recognition system is an HMM(Hidden Markov model)-based speaker-independent, continuous speech recognizer which can recognize about 300 word vocabularies. Bigram language model is used as a forward language model and dependency grammar is used for a backward language model. For machine translation, we use dependency grammar and direct transfer method. And Korean speech synthesizer uses the demiphones as a synthesis unit and the method of periodic waveform analysis and reallocation. KT-STS runs in nearly real time on the SPARC20 workstation with one TMS320C30 DSP board. We have achieved the word recognition rate of 94. 68% and the sentence recognition rate of 82.42% after the speech recognition tests. On Korean-to-Japanese translation tests, we achieved translation success rate of 100%. We had an international joint experiment in which our system was connected with another system developed by KDD in Japan using the leased line.

• The Journal of Korean Institute of Electromagnetic Engineering and Science
• /
• v.28 no.2
• /
• pp.97-104
• /
• 2017

In this paper, we designed and fabricated the multi band Transceiver Assembly(TCA) for the Multi Channel Synthetic Aperture Radar(MCSAR) containing C-band, X-band, Ku-band and we researched to verify electrical performance of TCA. The transceiver consists of transmitters, receivers, signal selection modules for each band, and stability oscillator, frequency synthesizer, controller, power distributor. The transceiver has a receive path selection and bandwidth selection functions in accordance with the operating mode. And the transceiver can transmit and receive all three bands simultaneously, each band has a bandwidth of up to 300 MHz. Final transmission output of transceiver for each band is over 20 dBm to be suitable for driving the T/R module. Receiver bandwidth is selected according to the required function and receiver gain has approximately C-band 52 dB, X-band 50 dB, Ku-band 60 dB, the maximum noise figure of Ku-band V polarization is 4.28 dB in the whole band H, V polarization. As a result of the electrical performance test, a multi-band TCA is satisfied the property requirements of the MCSAR.

• Journal of the Korean Institute of Intelligent Systems
• /
• v.8 no.2
• /
• pp.60-69
• /
• 1998

This paper proposes a speech synthesis method using Fuzzy VQ, and then study how to make choice of fuzziness value which optimizes (controls) the performance of FVQ in order to obtain the synthesized speech which is closer to the original speech. When FVQ is used to synthesize a speech, analysis stage generates membership function values which represents the degree to which an input speech pattern matches each speech patterns in codebook, and synthesis stage reproduces a synthesized speech, using membership function values which is obtained in analysis stage, fuzziness value, and fuzzy-c-means operation. By comparsion of the performance of the FVQ and VQ synthesizer with simmulation, we show that, although the FVQ codebook size is half of a VQ codebook size, the performance of FVQ is almost equal to that of VQ. This results imply that, when Fuzzy VQ is used to obtain the same performance with that of VQ in speech synthesis, we can reduce by half of memory size at a codebook storage. And then we have found that, for the optimized FVQ with maximum SQNR in synthesized speech, the fuzziness value should be small when the variance of analysis frame is relatively large, while fuzziness value should be large, when it is small. As a results of comparsion of the speeches synthesized by VQ and FVQ in their spectrogram of frequency domain, we have found that spectrum bands(formant frequency and pitch frequency) of FVQ synthesized speech are closer to the original speech than those using VQ.

• Korean Journal of Clinical Laboratory Science
• /
• v.55 no.4
• /
• pp.261-268
• /
• 2023

[¹⁸F]Fluorocholine is a radiopharmaceutical used non-invasively in positron emission tomography to diagnose parathyroid adenoma, prostate cancer, and hepatocellular carcinoma by evaluating the choline metabolism. In this study, a radiolabeling method for [¹⁸F]fluorocholine was optimized using a solid phase extraction (SPE) cartridge. [¹⁸F]Fluorocholine was labeled in two steps using an automated synthesizer. In the first step, dibromomethane was reacted with [¹⁸F]KF/K2.2.2/K₂CO₃ to obtain the intermediate [¹⁸F]fluorobromomethane. In the second step, [¹⁸F]fluorobromomethane was passed through a Sep-Pak^Ⓡ Silica SPE cartridge to remove the impurities and then reacted with N,N-dimethylaminoethanol (DMAE) in a Sep-Pak^Ⓡ C18 SPE cartridge to label [¹⁸F]fluorocholine. The reaction conditions of [¹⁸F]fluorocholine were optimized. The synthesis yield was confirmed according to the number of silica cartridges and DMAE concentration. No statistically significant difference in the synthesis yield of [¹⁸F]fluorocholine was observed when using four or three silica cartridges (P>0.05). The labeling yield was 11.5±0.5% (N=4) when DMAE was used as its original solution. On the other hand, when diluted to 10% with dimethyl sulfoxide, the radiochemical yield increased significantly to 30.1±5.2% (N=20). In conclusion, [¹⁸F]Fluorocholine for clinical use can be synthesized stably in high yield by applying an optimized synthesis method.

• The Journal of the Acoustical Society of Korea
• /
• v.26 no.4
• /
• pp.159-165
• /
• 2007

In this paper, we propose a new pre-selection of candidate units that is suitable for the unit selection based Japanese TTS system. General pre-selection method performed by calculating a context-dependent cost within IP (Intonation Phrase). Different from other languages, however. Japanese has an accent represented as the height of a relative pitch, and several words form a single accentual phrase. Also. the prosody in Japanese changes in accentual phrase units. By reflecting such prosodic change in pre-selection. the qualify of synthesized speech can be improved. Furthermore, by calculating a context-dependent cost within accentual phrase, synthesis speed can be improved than calculating within intonation phrase. The proposed method defines AP. analyzes AP in context and performs pre-selection using accentual phrase matching which calculates CCL (connected context length) of the Phoneme's candidates that should be synthesized in each accentual phrase. The baseline system used in the proposed method is VoiceText, which is a synthesizer of Voiceware. Evaluations were made on perceptual error (intonation error, concatenation mismatch error) and synthesis time. Experimental result showed that the proposed method improved the qualify of synthesized speech. as well as shortened the synthesis time.

• The Korean Journal of Nuclear Medicine Technology
• /
• v.14 no.2
• /
• pp.104-109
• /
• 2010

Purpose: $[^{18}F]$Fallypride plays an effective radiotracer for the study of dopamine $D_2/D_3$ receptor occupancy, neuropsychiatric disorders and aging in humans. This tracer has the potential for clinical use, but automated labeling efficiency showed low radiochemical yields about 5~20% with relatively long labelling time of fluorine-18. In present study, we describe an improved automatic synthesis of [$^{18}F$]Fallypride using different base concentration for routine clinical use. Materials and Methods: Fully automated synthetic process of [$^{18}F$]Fallypride was perform using the TracerLab $FX_{FN}$ synthesizer under various labeling conditions and tosyl-fallypride was used as a precursor. [$^{18}F$]Fluoride was extracted with various concentration of $K_{2.2.2.}/K_2CO_3$ from $^{18}O$-enriched water trapped on the ion exchange cartridge. After azeotropic drying, the labeling reaction proceeded in $CH_3CN$ at $100^{\circ}C$ for 10 or 30 min. The reaction mixture was purified by reverse phase HPLC and collected organic solution was exchanged by tc-18 Sep-Pak for the clinically available solution. Results: The optimal labeling condition of [$^{18}F$]Fallypride in the automatic production was that 2 mg of tosyl-fallypride in acetonitrile (1 mL) was incubated at $100^{\circ}C$ for 10 min with $K_{2.2.2.}/K_2CO_3$ (11/0.8 mg). [$^{18}F$]Fallypride was obtained with high radiochemical yield about $66{\pm}1.4%$ (decay-corrected, n=28) within $51{\pm}1.2$ min including HPLC purification and solid-phase purification for the final formulation. Conclusion: [$^{18}F$]Fallypride was prepared with a significantly improved radiochemical yield with high specific activity and shorten synthetic time. In addition, this automated procedure provides the high reproducibility with no synthesis failures (n=28).