• Title/Summary/Keyword: Synthesis value

Search Result 936, Processing Time 0.031 seconds

Content Analyses of Housing Unit of Secondary School Home Economics Textbooks in Japan (일본 중등학교 가정교과서 주생활영역의 교육내용 분석)

  • Jang, Sang-Ock
    • Journal of Korean Home Economics Education Association
    • /
    • v.22 no.4
    • /
    • pp.155-183
    • /
    • 2010
  • The purpose of this study is to obtain a suggestion for writing, revising, and reorganizing for the current Korean Home Economics Textbook. To achieve this goal, the housing unit in the Home Economics curriculums from eight kinds of Japanese textbooks were analyzed. The subject of analysis was Technology Home Economics textbook Home Economics Part 2 volumes used in middle school 2009 and Home Economics Synthesis 6 volumes in high school. Contents of main text, terminology, reading material, tables and activities were analyzed. The suggestions of this analysis are as followings. First according to the increase of the level of school, if the field of housing is organized to be intensified systematically with relation to education, the goal of the subject would be clearly realized to the students. Thus, the middle school curriculum and textbook of housing field should be constructed with the consideration of education level according to the grade and the level of school. The method of intensive education in single point of time would result in low efficiency so the current curriculum should be re-considered. Second, perspective of resident, local community, terrain environment, housing culture should be included in housing education so that the learner may value the relationship between him and the society, think of the earth environment, succeed and advance the traditional culture. Third, the curriculum of the housing field should be organized with the consideration of understanding the level of middle, high school students. Middle school, with their student's low understanding, should include more experiential activity such as experiment and practice in their curriculum. On the other hand, curriculum which can enable student to research problems on their own and to apply them in their real life is required in high school course.

  • PDF

New Gene Profiling in Determination of Breast Cancer Recurrence and Prognosis in Iranian Women

  • Poorhosseini, Seyed Mohammad;Hashemi, Mohammad;Olyaei, Nasrin Alipour;Izadi, Amir;Moslemi, Elham;Ravesh, Zeinab;Hashemi-Gorji, Feyzollah;Kheiri, Hamid Reza;Yassaee, Vahid Reza
    • Asian Pacific Journal of Cancer Prevention
    • /
    • v.17 no.sup3
    • /
    • pp.155-160
    • /
    • 2016
  • Breast cancer (BC) is the second most common cancer in the world and by far the most frequent cancer among women, with an estimated 1.67 million new cancer cases diagnosed in 2012 (25% of all cancers). Polygene expression analysis is used to predict the prognosis and determine the most appropriate treatment regimen. The objective of this study was to examine the gene expression profiles of SIRT3, HRAS, LSP1, SCUBE2 and AP2A2 in Iranian women with BC.A total of 136 patients including healthy controls were categorized into three groups based on the relapse of the disease. Expression of desired genes in formalin-fixed, paraffin embedded tissues collected from all groups of participants was analyzed via the RT PCR method. RNA extraction and cDNA synthesis were performed then real-time quantitative PCR was carried out. Gene expression analysis revealed that the expression of SIRT3 was equal among patient and control groups. LSP1 was down regulated in all patient groups relative to controls but reduced expression in the metastatic group relative to the non-metastatic one was not significant. HRAS was significantly overexpressed in total and metastatic tumor samples versus normal but not in non-metastatic cases. SCUBE2 expression showed significant over-expression in both overall tumor samples and the non-metastatic group as compared to normal tissues. Gene expression level of AP2A2 in all groups was not detectable. Our data are compatible with a tumor suppressor role of LSP1 related to potential prognostic factor for tumor recurrence and outcome. This study for the first time assayed the prognostic value and changes in the expression of SIRT3, LSP1, HRAS, SCUBE2 and AP2A2 genes in women with breast cancer in the Iranian population and findings confirmed potential biomarker and prognostic capability of these genes. Such expression profiling data can critically improve prognosis and treatment decisions in cancer patients.

Effects of Supplementation of Mulberry (Morus alba) Foliage and Urea-rice Bran as Fermentable Energy and Protein Sources in Sheep Fed Urea-treated Rice Straw Based Diet

  • Yulistiani, Dwi;Jelan, Z.A.;Liang, J.B.;Yaakub, H.;Abdullah, N.
    • Asian-Australasian Journal of Animal Sciences
    • /
    • v.28 no.4
    • /
    • pp.494-501
    • /
    • 2015
  • A digestibility study was conducted to evaluate the effects of supplementing mulberry foliage and urea rice-bran as a source of fermentable energy and protein to 12 sheep fed diets based on urea-treated rice straw (TRS). The three dietary treatments were: T1, TRS with mulberry; T2, TRS with 50% mulberry replaced with rice bran and urea; and T3, TRS with rice bran and urea. The study was arranged in a completely randomized design with four replications for each treatment. The sheep were fed one of the three diets and the supplements were offered at 1.2% of the body weight (BW) and the TRS was provided ad libitum. There were no differences (p>0.05) among the three treatment groups with respect to dry matter (DM) intake ($76.8{\pm}4.2g/kg\;BW^{0.75}$) and DM, organic matter (OM), and crude protein (CP) digestibility ($55.3{\pm}1.22$; $69.9{\pm}0.85$; $46.3{\pm}1.65%$ respectively for DM, OM, and CP). The digestibility of fiber (neutral detergent fiber [NDF] and acid detergent fiber) was significantly lower (p<0.05) for T3 (46.2 and 46.6 respectively) compared to T1 (55.8 and 53.7 respectively) and T2 (54.1 and 52.8 respectively). Nitrogen (N) intake by sheep on diet T3 was significantly (p<0.05) higher than sheep fed diet T1. However, N balance did not differ among the three diets ($3.0{\pm}0.32g/d$). In contrast, the rumen ammonia ($NH_3-N$) concentrations in sheep fed T2 and T3 were significantly (p<0.05) higher than in sheep fed T1. The $NH_3-N$ concentrations for all three diets were above the critical value required for optimum rumen microbial growth and synthesis. Total volatile fatty acid concentrations were highest (p<0.05) in T1 (120.3 mM), whilst the molar proportion of propionic acid was highest in T3 (36.9%). However, the microbial N supply in sheep fed T1 and T3 was similar but was significantly (p<0.05) higher than for sheep fed T2. It was concluded that mulberry foliage is a potential supplement of fermentable energy and protein for sheep fed TRS based diet. The suggested level of supplementation is 1.2% of BW or 32% of the total diet since it resulted in similar effects on the intake of DM, OM, and NDF, digestibility of DM, OM, and CP, N utilization and microbial supply when compared to rice bran and urea supplementation.

Manufacture of 11CaOㆍ$7Al_2O_3$$CaCl_2$Clinker Using the Bottom Ash of Municipal Solid Waste Incinerator Ash (생활폐기물 소각재중 바닥재를 이용한 11CaOㆍ$7Al_2O_3$$CaCl_2$클링커의 제조)

  • Ahn Ji-Whan;Kim Hyung-Seok;Han Gi-Ckun;Cho Jin-Sang;Han Ki-Suk
    • Resources Recycling
    • /
    • v.11 no.4
    • /
    • pp.27-36
    • /
    • 2002
  • The clinker of which main component was calcium-chloroaluminate ($l1CaOㆍ7Al_2$$O_3$$CaCl_2$), was synthesized with the bottom ash of municipal solid waste incinerator ash. The hydration mechanism and synthesis temperature of calcium-chloro-aluminate were investigated. The synthesized clinker was blended with a cement. It was substituted with 3~13 wt.% for clinker and $CaSO_4$ of ordinary portland cement. The compressive strength and the content of leached heavy metals of its mortar were measured. Calcium-chloroaluminate was synthesized above $800^{\circ}C$ and its main hydrate was ettringite ($3CaOㆍAl_2$$O_3$$3CaSO_4$$32H_2$O). The calcium-chloroaluminate was also synthesized above $800^{\circ}C$ with the bottom ash of which size fraction was below 30 mesh mainly. The compressive strength of the blended cement mortar was increased as the additive content of the clinker synthesized from the bottom ash was increased by 11 wt.%. The concentration of heavy metals leached from each mortar was satisfied with the value of the environmental standards and regulations.

Synthesis and Characterization of Zeolite 4A on Activated Carbon Supports (활성탄 지지체상에서 제올라이트 4A 합성 및 특성)

  • Park, Jeong-Hwan;Suh, Jeong-Kwon;Jeong, Soon-Yong;Lee, Jung-Min;Doh, Myung-Ki
    • Applied Chemistry for Engineering
    • /
    • v.8 no.2
    • /
    • pp.204-210
    • /
    • 1997
  • Zeolite 4A-impregnated complex molecular sieve was prepared by hydrothermal reaction after aluminosilicate gel was penetrated into the pore of activated carbon granule. The crystals of zeolite 4A mainly were formed in the macropore of activated carbon, and their average diameter is $0.8{\mu}m$. The pore volume of activated carbon granule is $0.67m{\ell}/g$, and the pore volume of the sample including 21.6wt% of zeolite 4A crystal is $0.41m{\ell}/g$ decreasing the pore volume by 40% due to the crystallization of zeolite 4A crystals on the internal surface of activated carbon. The calcium ion exchange capacity of zeolite 4A-impregnated sample is 320mg $CaCO_3/g$ zeolite, and this value is almost the same as that of zeolite 4A powder. The crystal of zeolite 4A was not separated from the support of activated carbon granule in the course of ultrasonic dispersion. The adsorption isotherm of water on zeolite 4A-impregnated sample shows the intermediate shape between types, I and III. In addition, zeolite 4A-impregnated sample shows the hydrophilic and hydrophobic properties simultaneously.

  • PDF

Development of Vibration and Impact Noise Damping Wood-Based Composites -Synthesis of the Polymer Showing a Broad Damping Peak (진동·충격음 흡수성 목질계 복합재료의 개발 -폭 넓은 감쇠곡선을 나타내는 고분자의 합성-)

  • Lee, Hyun-Jong
    • Journal of the Korean Wood Science and Technology
    • /
    • v.27 no.2
    • /
    • pp.15-22
    • /
    • 1999
  • Polymeric meterials that are used for noise and vibration damper in wood/polymer/wood sandwich composites, must have a high loss factor(tan ${\delta}$), and at the same time the storage modulus(E) of $5{\times}10^7$ to $10^9$ dyne/$cm^2$ must withstand over a wide temperature and frequency ranges. In this study, the series of epoxy resinlpolyacrylate interpenetrating polymer networks(IPNs) were synthesized by simultaneous polymerization. Their dynamic tensile properties were measured at 110Hz using Rheovibron instrument. Composite damping factor(tan ${\delta}_c$) and dynamic bending modulus($E_c,\;E_^{\prime\prime}c$) of wood/polymer/wood sandwich composites were measured at 110Hz using a Rheovibron in bending mode of vibration. These dynamic tensile studies indicated that cured epoxy resin/polyacrylates IPNs were semicompatible in the sense that both the shifting of T($E^{\prime\prime}_{max}$) or T(tan ${\delta}_{max}$) and the broadening of glass transition temperature range were observed. Especially, the cured Epikote871/P(n-BMA) IPNs of composition 70/30 to 50/50 showed a relatively high tan a and appropriate E' value over a wide temperature range; consequently the tan a e curves of wood/IPNs/wood sandwich composites was broadened over a wide temperature range.

  • PDF

Rhythmic Control and Physiological Functional Significance of Melatonin Production in Circadian Rhythm (주기적 리듬 조절에 의한 멜라토닌 생산과 생리적 기능의 중요성)

  • Kim, Min Gyun;Park, Seul Ki;Ahn, Soon Cheol
    • Journal of Life Science
    • /
    • v.23 no.8
    • /
    • pp.1064-1072
    • /
    • 2013
  • Circadian rhythm is controlled by hormonal oscillations governing the physiology of all living organisms. In mammals, the main function of the pineal gland is to transform the circadian rhythm generated in the hypothalamic suprachiasmatic nucleus into rhythmic signals of circulating melatonin characterized by a largely nocturnal increase that closely reflects the duration of night time. The pineal gland has lost direct photosensitivity, but responds to light via multi-synaptic pathways that include a subset of retinal ganglion cells. Rhythmic control is achieved through a tight coupling between environmental lighting and arylalkylamine-N-acetyltransferase (AANAT) expression, which is the rhythm-controlling enzyme in melatonin synthesis. Previous studies on the nocturnal expression of AANAT protein have described transcriptional, post-transcriptional, and post-translational regulatory mechanisms. Molecular mechanisms for dependent AANAT expression provide novel aspects for melatonin's circadian rhythmicity. Extensive animal research has linked pineal melatonin for the expression of seasonal rhythmicity in many mammalian species to the modulation of circadian rhythms and to sleep regulation. It has value in treating various circadian rhythm disorders, such as jet lag or shift-work sleep disorders. Melatonin, also, in a broad range of effects with a significant regulation influences many of the body's physiological functions. In addition, this hormone is known to influence reproductive, cardiovascular, and immunological regulation as well as psychiatric disorders.

Hydrothermal Synthesis of Li-Mn Spinel Nanoparticle from K-Birnessite and Its Electrochemical Characteristics (K-Birnessite를 이용한 Li-Mn Spinel 나노입자 합성 및 전기화학적 특성 평가)

  • Kim, Jun-Il;Lee, Jae-Won;Park, Sun-Min;Roh, Kwang-Chul;Sun, Yang-Kook
    • Applied Chemistry for Engineering
    • /
    • v.21 no.5
    • /
    • pp.590-592
    • /
    • 2010
  • Li-Mn spinel ($LiMn_2O_4$) is prepared by a hydrothermal process with K-Birnessite ($KMnO_4{\cdot}yH_2O$) as a precursor. The K-Birnessite obtained via a hydrothermal process with potassium permanganate [$KMnO_4$] and urea [$CO(NH_2)_2$] as starting materials are converted to Li-Mn spinel nanoparticles reacting with LiOH. The molar ratio of LiOH/K-Birnessite is adjusted in order to find the effect of the ratio on the structural, morphological and electrochemical performances of the Li-Mn spinel. X-ray diffraction (XRD) and field emission scanning electron microscopy (FE-SEM), energy-dispersive X-ray spectroscopy (EDS), and thermogravimetry (TG) are used to investigate the crystal structure and morphology of the samples. Galvanostatic charge and discharge are carried out to measure the capacity and rate capability of the Li-Mn spinel. The capacity shows a maximum value of $117\;mAhg^{-1}$ when the molar ratio of LiOH/K-Birnessite is 0.8 and decreases with the increase of the ratio. However the rate capability is improved with the increase of the ratio due to the reduction of the particle size.

Synthesis and Characterization of Interfacial Properties of a Cationic Surfactant Having Three Hydroxyl Groups (세 개의 히드록실기를 가진 양이온 계면활성제 합성 및 계면 특성에 관한 연구)

  • Lee, Byung Min;Kim, Ji-Hyun;Kim, Sung Soo;Lim, Jong Choo
    • Applied Chemistry for Engineering
    • /
    • v.23 no.5
    • /
    • pp.433-439
    • /
    • 2012
  • In this study, a cationic surfactant BHMAS (N,N-bis-(3'-n-dodecyloxy-2'-hydroxypropyl)-N-methyl-2-hydroxyethylammonium methyl sulfate) having two lauryl and three hydroxyl groups was synthesized by the reaction of n-dodecyl glycidyl ether and 2-aminoethanol followed by the quarternization with dimethyl sulfate. The structure of the product was elucidated by $^{1}H-NMR$ and FT-IR. The CMC (critical micelle concentration) and surface tension of BHMAS at CMC condition were found to be $9.12\;{\times}\;10^{-4}$ mol/L and 28.71 mN/m respectively. Dynamic surface tension measurements using a maximum bubble pressure tensiometer indicated that a relatively long time was required to saturate the interface between air and aqueous surfactant solution. The interfacial tension measured between 1 wt% surfactant solution and n-decane reached an equilibrium value of 0.045 mN/m in 5 min. The adsorption capacity of the synthesized surfactant was observed to be excellent, which suggests that the surfactant can be used as a softening agent during a laundry process.

Inhibitory effect of Nymphoides indica extract on α-MSH induced melanin synthesis (어리연꽃 추출물이 α-MSH 유도에 의한 멜라닌 생성 억제에 미치는 영향)

  • Kim, Dong-Hee;Kim, You-Ah;Yu, Jae-Myo;Park, Chae-Bin;Park, Byoung-Jun;Park, Tae-Soon
    • Journal of Applied Biological Chemistry
    • /
    • v.60 no.4
    • /
    • pp.327-332
    • /
    • 2017
  • In this study, the whitening activity of Nymphoides indica extract in B16F10 cells were measured. Inhibition rate of tyrosinase from mushroom was 42% at $1,000{\mu}g/mL$. And inhibition of tyrosinase and melanin biosynthesis in B16F10 cells were 26 and 25% at $5{\mu}g/mL$, respectively. The expression levels of cAMP and protein kinase A (PKA), which are higher levels of melanin-related factors, were found to be decreased in a dose-dependent manner. In addition, the expression rate of protein and mRNA of tyrosinase, tyrosinase related protein 1 (TRP1), tyrosinase related protein 2 (TRP2) and microphthalmia associated transcription factor (MITF). In this study, it was confirmed that the N. indica extract effectively inhibited the activity of tyrosinase, TRP1, TRP2 and MITF as well as the activity of PKA by effectively inhibiting cAMP. Therefore, it was confirmed that the N. indica extract has high value as a functional material.