• Psychiatry investigation
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• 제15권12호
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• pp.1130-1134
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• 2018

Objective Trichotillomania is a relatively common illness whose neurobiology is poorly understood. One treatment for adult trichotillomania, n-acetyl cysteine (NAC), has antioxidative properties, as well as effects on central glutamatergic transmission. Preclinical models suggest that excessive oxidative stress may be involved in its pathophysiology. Methods Adults with trichotillomania provided a blood sample for analysis of compounds that may be influenced by oxidative stress [glutathione, angiotensin II, ferritin, iron, glucose, insulin and insulin growth factor 1 (IGF1), and hepcidin]. Participants were examined on symptom severity, disability, and impulsivity. The number of participants with out-of-reference range oxidative stress measures were compared against the null distribution. Correlations between oxidative stress markers and clinical measures were examined. Results Of 14 participants (mean age 31.2 years; 92.9% female), 35.7% (n=5) had total glutathione levels below the reference range (p=0.041). Other oxidative stress measures did not have significant proportions outside the reference ranges. Lower levels of glutathione correlated significantly with higher motor impulsiveness (Barratt Impulsiveness Scale sub-score) (r=0.97, p=0.001). Conclusion A third of patients with trichotillomania had low levels of glutathione, and lower levels of glutathione correlated significantly with higher motor impulsiveness. Because NAC is a precursor for cysteine, and cysteine is a rate limiting step for glutathione production, these results may shed light on the mechanisms through which NAC can have beneficial effects for impulsive symptoms. Confirmation of these results requires a suitable larger follow-up study, including an internal normative control group.

• Journal of the Korean Academy of Child and Adolescent Psychiatry
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• 제30권4호
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• pp.178-184
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• 2019

Objectives: The aim of this study was to measure the effect of a group-based parent education program on parenting stress and attitude and comparing the same according to adult attachment styles. Methods: Twenty-two mothers who enrolled in the parent education program participated in our study. The participants filled in the Korean version of the Experience in Close Relationship Revised (ECR-R), Korean-Parenting Stress Index-Short Form (K-PSI-SF), Maternal Behavior Research Instrument (MBRI), and Symptom Checklist-90-Revised (SCL-90-R) before and after the program. We compared the pre - and post-scores of the groups and compared the differences in effect according to adult attachment styles. Results: For all study participants, the Parent Distress (p=0.023) and Total Parenting Stress (p=0.018) significantly declined after the parent education program. There were no differences in other variables. Within the secure attachment group, the Total Parenting Stress (p=0.008), Parent Distress (p=0.015), and Difficult Child (p=0.011) scores in the K-PSI-SF significantly decreased after participating in the program. The Difficult Child scores (p=0.040) significantly dropped in the K-PSI-SF post program within the secure attachment group, compared to the insecure attachment group. Conclusion: The group-based parent education program impacted parenting stress. Depending on the adult attachment styles, the effect of the program varied.

• 정신신체의학
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• 제11권1호
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• pp.36-43
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• 2003

연구목적: 본 연구의 목적은 외상후 스트레스 장애에서 증상의 정도에 따른 인지기능의 차이가 어떠한지에 대하여 연구한 것이다. 방 법: 교통사고 관련 외상후 스트레스 장애로 진단된 90명의 외래, 입원환자를 대상으로 외상후 스트레스 장애 증상의 심각도(MMPI 우울증 척도, 강박 척도, 정신분열증 척도)와 인지기능(K-WAIS)을 측정하였다. 그들을 MMPI 우울증 척도, 강박증 척도, 정신분열증 척도 점수에 따라 상위 30%에 해당하는 집단과 하위 30%에 해당하는 집단으로 구분하여 두 군간의 지능과 소검사 점수 차이에 대하여 각각 검증하였다. 결 과: 우울증 척도의 상위군과 하위군 사이에 유의한 차이는 없었다. 그리고 강박 척도에서 하위군이 상위군보다 기본지식, 어휘문제, 공통성문제, 빠진곳 찾기, 차례맞추기가 유의하게 높았다. 그리고 정신분열증 척도에서 하위군이 상위군보다 전체지능, 언어성지능, 동작성지능, 기본지식, 어휘문제, 이해문제, 산수문제, 빠진곳 찾기, 차례맞추기, 토막짜기, 모양맞추기, 바꿔쓰기가 유의하게 높았다. 결 론: 본 연구 결과, 외상후 스트레스 장애에서 증상의 정도에 따른 인지기능의 차이가 있었다. 따라서 증상의 정도가 심한 집단에서 인지기능 장애가 더 심하다는 것을 알 수 있었다. 그러므로 외상후 스트레스 장애는 불안장애이기도 하지만 인지기능 또한 증상에 의해 많은 영향을 받는다는 것을 알 수 있었다. 향후 외상후 스트레스 장애를 치료함에 있어서 약물치료 뿐만이 아니라 다양한 인지적 치료 접근이 필요할 것으로 생각된다.

• 대한간호학회지
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• 제42권1호
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• pp.105-115
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• 2012

Purpose: This study was done to propose a structural model to explain and predict psychosocial adjustment in patients with early breast cancer and to test the model. The model was based on the Stress-Coping Model of Lazarus and Folkman (1984). Methods: Data were collected from February 18 to March 18, 2009. For data analysis, 198 data sets were analyzed using SPSS/WIN12 and AMOS 7.0 version. Results: Social support, uncertainty, symptom experience, and coping had statistically significant direct, indirect and total effects on psychosocial adjustment, and optimism had significant indirect and total effects on psychosocial adjustment. These variables explained 57% of total variance of the psychosocial adjustment in patients with early breast cancer. Conclusion: The results of the study indicate a need to enhance psychosocial adjustment of patients with early breast cancer by providing detailed structured information and various symptom alleviation programs to reduce perceived stresses such as uncertainty and symptom experience. They also suggest the need to establish support systems through participation of medical personnel and families in such programs, and to apply interventions strengthening coping methods to give the patients positive and optimistic beliefs.

• 정신신체의학
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• 제28권2호
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• pp.135-142
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• 2020

연구목적 간호사의 신체화 증상과 스트레스, 우울 및 불안, 정신 증상 위험의 관계를 확인하여 정신신체의학 연구의 임상 근거를 창출하고, 신체화 증상의 의미에 대해 제고하는 것을 목적으로 한다. 방 법 서울시 내 1개 상급종합병원 외과계 중환자실 간호사 70명에게 자가기입형 도구(Perceived Stress scale, Fatigue Severity Scale, Patient Health questionnaire-15, Korean Beck Depression Inventory, Korean Beck Anxiety Inventory, Symptom Checklist-90-Revision)를 사용하여 수집한 데이터를 분석하였다. 결 과 대상자 중 12.9%가 신체화 증상을 경험하였고 피로, 낮은 에너지, 생리통, 허리 통증이 나타났다. 신체화 증상과 정신적 스트레스 인지의 통계적 관련성은 없었으나 불안한 느낌이나, 자신감의 감소는 신체화 증상의 수준과 관련이 있었다. 신체화 증상이 심한 집단은 우울, 불안을 더 많이 경험하였다. 신체적 피로가 높은 집단은 정신적 스트레스 인지의 통계적 관련성은 없었으나 긴장이나 스트레스를 느끼거나 통제력이 감소되는 경험에 영향을 미쳤다. 신체적 피로 수준의 증가는 불안과는 관련이 없었고 우울을 더 많이 경험하는 것으로 확인되었다. 신체화 수준이 높을수록 정신 증상 중 강박과 적대감이 증가하였다. 선형회귀모형에서 스트레스, 우울, 불안은 신체화 증상을 39.3%, 신체적 피로 증상을 16.1% 설명하였다. 결 론 이 연구의 결과를 바탕으로 우리는 한국 문화에서 신체화 증상의 특징으로 스트레스 인지 증상의 감소, 우울과 불안 경험, 강박 및 적대감의 동반 가능성을 추정할 수 있다. 이 연구에서 신체화와 정신 증상은 인과관계를 확인할 수 없었으나 상호관련성이 관찰되어 향후 중재 전략 마련에 참조할 수 있을 것이다.

• 대한치과기공학회지
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• 제23권2호
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• pp.105-119
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• 2002

This study was designed to grasp the degree of job stress affecting dental technicians and the degree of the symptoms of their job stress. With this in mind, the researcher selected a total of 170 dental technicians living in Seoul and Incheon, conducting a research in a period ranging from August 1,2001, to August 20, 2001. The researcher made use of a structured questionnaire whose reliability and feasibility are proved. The questionnaire is composed of a total of 55 questions: thirteen questions related to the subjects' general characteristics; 28 questions connected to the measurement of job stress and fourteen questions linked with the measurement of job-stress symptoms. The researcher analyzed the findings with the aid of SPSS(Statistical Package for Social Sciences). The research came to draw the following conclusions on the basis of frequency, percentage, T-test, and F-test, multiple regression. I. The analysis into the job stress of the subjects indicates that there is a significant difference in difficult questions among their work places, working hours, academic background, job satisfaction and jobs(P<.05). The job stress stands at 3.48 on the average, and the area of conflict among too much work and job performance turns out to be highly perceived. 2. The analysis into the degree of the symptoms of the job stress of the subjects shows that there is a significant difference in work place, working hours, job satisfaction and the continual maintenance of job(P<.05). The symptoms of job stress accounts for 2.65 on the average. Physical symptoms turn out to be highly perceived; The response 'My arms and legs are killing me' proves to stand for 3.03. 3. The correlation between job stress and the symptoms of job stress turns out to be significant(r=0.519, P<0.001), and there is a significant correlation between the average points of each job-stress area and the average points of the symptoms of job stress. All in all, it is necessary that dental technicians themselves should make positive efforts to control and relieve stress and that more efficient programs should be implemented with a view to dealing with stress.

• Journal of Korean Biological Nursing Science
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• 제22권2호
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• pp.90-101
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• 2020

Purpose: The purpose of this study was to build and verify a structural model that could predict the severity of irritable bowel syndrome in university students. Methods: Participants were 205 students enrolled in college with irritable bowel syndrome using the irritable bowel syndrome module of the ROME IV Adult Questionnaire. The data were collected using online questionnaires in AprilMay 2019. The data were analyzed using the SPSS WIN 25.0 and AMOS 20.0 programs. Results: 1) The symptom severity that participants experienced were mild (14.6%), moderate (45.4%), and severe (40%). 2) Fit indices of the model were x²= 79.66 (df = 52, p= .009), CFI= .94, TLI= .96, RMSEA= .05, RMR= 1.59, GFI= .94, and TLI= .96.3). The severity of irritable bowel syndrome was influenced directly by anxiety and sleep, and indirectly by family history, perfectionism, social support, coping, and stress. The severity of irritable bowel syndrome was indirectly affected by the following: family history through anxiety; perfectionism through stress, anxiety, and sleep; social support through coping, stress, anxiety, and sleep; coping through stress and anxiety; and stress through anxiety and sleep. Conclusion: Based on the results of this study, a nursing intervention is needed to reduce the anxiety and stress and improve the quality of sleep to improve the health of the college students and manage the symptoms of patients with irritable bowel syndrome.

• 한국직업건강간호학회지
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• 제21권3호
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• pp.229-238
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• 2012

Purpose: The purpose of this study was to measure the fatigue of operating room nurses and examine factors contributing to their fatigue. Methods: The subjects of this study were 115 nurses who worked in operating rooms of three hospitals. Data were collected from September 15, 2009 to September 30, 2009. Fatigue and job stress were measured by using the Symptom's Fatigue Scale and the job stress measurement tools in operating room nurses. Results: The mean score of fatigue level was $3.10{\pm}0.61$. We analyzed fatigue according to characteristics of subjects and found that there were significant differences in marital status, number of children and sleeping hours in general characteristics. Career, daily participation hours in the surgery relating to job related characteristics. Significant positive correlations were found between job stress and fatigue(r=.233, p= .012). Three significant variables influencing fatigue of operation rooms nurses were job stress, daily participation hours in the surgery, and sleeping hours (Adj. $R^2$=0.284, F=4.773, p<.001). Conclusion: An integrative care program that takes job stress, daily participation hours in the surgery and sleeping hours into consideration is essential to reduce fatigue in operating room nurses.

• 대한치과기공학회지
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• 제39권3호
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• pp.187-196
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• 2017

Purpose: The purpose of this study was to investigate the factors contributing to temporomandibular joint disorder symptoms. Methods: The survey was conducted from May 1 to June 10 2017 against college students(120 males and 123 females) in Daejeon and Gangwon who understood the purpose of this study and agreed to participate. Results: First, The most frequent symptom of temporomandibular joint disorders is noises from the joint (male 45%, female 61.8%), followed by headache or neck pain (male 25.8%, female 52.8%). There was shown a significant difference by gender in all items except for jaw dropping, poor alignment of teeth and trauma(p<0.05). Second, Looking into the correlation between stress and subjective symptoms of Temporomandibular joint disorders, The stress of Temporomandibular joint disorders showed more significant relation with realistic issues such as academic task, economic burden (e.g., treatment cost), future career, and life values rather than aspect of social relationship(p<0.01). Conclusion: As a result of analyzing variables to understand the influence of stress on temporomandibular joint disorders, the accumulated number of bad habits, stress and temporomandibular joint disorders showed a significantly positive correlation with one another (p<0.05). In other words, the higher the stress level the severe the temporomandibular joint disorders; the more the bad habits the severe the temporomandibular joint disorders;

• 대한임상검사과학회지
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• 제46권2호
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• pp.68-74
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• 2014

The purpose of this study is to provide an academic basis regarding the necessity of managing depression and stress among metabolic syndrome patients by understanding 5 components of metabolic syndrome, perceived stress, and degree of depression, and by investigating their association using the national nutrition survey reference. This study was conducted by using mental health surveys and health screening test data of the 5th (2010~2012) primitive data of the national health and nutrition survey. A total of 19,599 respondents over 19 years of age were selected for the final analysis. The level of depression and stress was set as the dependent variable to identify its connection with 5 components of the metabolic syndrome. For the stress recognition, none of the metabolic syndrome components showed a significant correlation. For experiencing the depression symptom, the fasting glucose among the factors showed a significant correlation (p<0.05) among the metabolic syndrome factors. When it falls within the criteria of fasting glucose of metabolic syndrome, it has a great probability of falling under the group who experienced greater depression symptoms. As a result of the analysis by controlling cardiovascular and cerebrovascular disease which is tightly related with metabolic syndrome and depression, this study observed that glucose out of 5 metabolic syndrome components is related with depression.