• 약학회지
• /
• 제35권6호
• /
• pp.486-496
• /
• 1991

Spinal parasympathetic outflows originate in the sacral parasympathetic nuclei. The sacral parasympathetic nuclei receive inputs from the brainstem. Many areas in the medulla appear to influence sympathetic outflow of the spinal cord. Whether neurons in these areas of the medulla may project to the lumbosacral cord to affect the parasympathetic outflow has not been studied clearly. Thus, this study was intended to investigate origins of cells projecting from the medulla to the sacral parasympathetic nuclei of the spinal cord. In 3 cats, horseradish peroxidase (HRP) was injected into the lower lumbar spinal cord. HRP labeled neurons were found mainly in the following areas: nucleus retroambiguus, nucleus tractus solitarius, raphe complex and ventrolateral area of the rostral medulla. Most of these areas are known to be involved in regulation of sympathetic activity, and, thus, these results indicate that these areas are likely to affect the sacral parasympathetic outflow as they do for the sympathetic nerves.

• 비만대사연구학술지
• /
• 제2권2호
• /
• pp.37-44
• /
• 2023

Weight gain is defined as the increase in body weight, increasing the prevalence of obesity, and results in metabolic diseases. Weight gain was reportedly caused by the interaction between the obesogenic environmental factors and individual metabolic factors. Sociodemographic and environmental factors (demographic factors, lifestyle/behavioral factors, food/nutritional factors, socioeconomic factors), drug-related secondary causes (some of the corticosteroids, antihyperglycemics, antihypertensives, antidepressants, etc.), and metabolic factors (aging and hormonal changes, menopause and decreased sex hormones, decreased adipocyte degradation, decreased fibroblast growth factor 21, central sympathetic nervous system hyperactivity, decreased sympathetic-adrenomedullary system activity) are significant factors related to weight gain. It is crucial to prevent weight gain and maintain an ideal weight, but studies on the risk factors of weight gain are insufficient. Therefore, this study evaluated the factors associated with weight gain to find strategies for preventing unnecessary weight gain.

• 대한임상전기생리학회지
• /
• 제5권2호
• /
• pp.11-21
• /
• 2007

The purpose of this study were to investigate influence of heat stress temperature on sympathetic nerve activities. Subjects were 8 normal adults (4 men, 4 women, 21.36 years old). First sympathetic nerve activities were measured at the point that increase of core temperature stops at the state of applying normal thermic temperature (NIT; $34^{\circ}C$). After measurement, temperature of bathtub was increased to heat stress temperature (HST; $46^{\circ}C$) and sympathetic nerve activities were remeasured at the point that temperature increase stops. Sympathetic skin response (SSR) were analyzed using EMG, IR thermometer, and auto stethoscope. SSR latency showed significant differences at both palms by electrical stimulation to median nerve (p<.05). Electrical stimulation to forehead showed significant difference at left palm (p<.05) and electrical stimulation to navel showed significant difference at right palm (p<.05). Median nerve in changes of SSR amplitude showed significant differences at both palms in HST (p<.01). Electrical stimulation to navel showed significant difference at left palm (p<.05). Ts of forehead and xiphoid process showed significant differences (p<0.01). Tc of oral (p<0.05) and inner ear (p<0.01) showed significant differences. Pulse rate showed significant difference (<0.05). This study showed that immersion in HST had significant decrease of excitability in sympathetic nervous system compared to immersion in NTT.

• 감성과학
• /
• 제16권4호
• /
• pp.509-516
• /
• 2013

본 연구는 3D 산업의 안전성 문제인 3차원 콘텐츠로 유발된 시각피로를 안면 온도 변화로 정량화하는 방법을 제안하고자 한다. 콘텐츠 시청 전과 후에 각 1분간 열화상 카메라를 이용하여 안면온도를 측정하였고 주관설문과 인지부하 실험을 통해 시각피로를 판단하였다. 2D와 3D의 시청 전과 후를 비교하여 3D 콘텐츠 시청에 따른 시각피로 유발 시 안면 온도에 차이를 확인하였다. 시청 전과 후에 차이를 비교한 결과 주관 설문과 인지부하 실험은 유의한 차이를 보였고 ERP latency는 3D 시청 시 증가하는 것으로 나타났다. 안면 온도의 경우 미간(forehead)과 코끝(tip of the nose) 영역의 최대값을 비교 결과 유의한 차이를 보였다. 선행 연구에서 3D 시각피로 발생 시 교감신경계가 항진됐던 결과와 비교해보면 교감신경계가 항진되면 심박 수가 증가하고 목동맥계(carotid arteries system)를 통한 안면으로의 혈류량이 증가하게 된다. 2D와 3D 시청 시 교감신경계 항진 정도에 따라서 혈류량 변화로 안면 온도에 영향을 미치는 것으로 확인되었다. 본 연구는 열화상이미지를 이용한 3D 시각피로 측정 가능성을 확인하는데 의의가 있다.

• 한방재활의학과학회지
• /
• 제23권1호
• /
• pp.51-64
• /
• 2013

Objectives : This study was performed to evaluate the effect of dry cupping treatment applied to back-shu points on the autonomic nervous system. Methods : Two groups of sympathicotonia and normal with each 30 volunteers were set up for this experiment. The sympathicotonia group was selected by the criterion for sympathicotonia by the questionnaire composed of 11 items. After 10 minutes for environmental adaptation, the first HRV(heart rate variability) test was conducted, and then, dry cupping therapy was applied to back-shu points for 5 minutes to stimulate sympathetic ganglia lying along the spine. The second HRV test was carried out just after the cupping therapy under the same condition and then, the third test was repeated after two hours based on the first test time. Results : 1. In sympathicotonia group, SDNN(standard deviation of all normal R-R intervals), RMSSD(the square root of the mean of the sum of the squares of differences between adjacent normal R-R intervals), Ln(HF)(high frequency power), nmHF(normalized high frequency power) increased and mHR(mean heart rate), nmLF(normalized low frequency power) decreased significantly right after dry cupping therapy which means dry cupping affects on autonomic nervous system. The effect lasts in these items of nmLF, Ln(HF), nmHF, rLHF(rate ratio of LF/HF). 2. In normal group, SDNN, RMSSD increased and mHR decreased significantly right after dry cupping therapy, too. But, Ln(LF)(low frequency power), nmLF, rLHF unexpectedly increased and nmLF, rLHF stay increased up to 2 hours. Conclusions : The results suggest that the dry cupping therapy has effect on the autonomic nervous system. It is effective to stabilize hyper-sympathetic tone of people diagnosed as Sympathicotonia and activate parasympathetic tone.

• 산업경영시스템학회지
• /
• 제25권2호
• /
• pp.11-18
• /
• 2002

Psychological and physiological effects of the simulator sickness could be important bias factors for the sensibility evaluation. The purpose of the present study was to clear the differences of psychophysiological responses due to individual sensitivity of simulator sickness. The present experiment tried to investigate the simulator sickness objectively by observing the change of the simulator sickness for the different level of sickness groups (sick and non_sick group). The subjective evaluations using Simulator Sickness Questionnaire (SSQ) and physiological responses were measured every five minutes when they were driving as 60km/h in the driving graphic simulator. Response level of the subjective evaluation for all subjects on the simulator sickness was linearly increased with time for every item, and the response level of sick group was bigger than that of non_sick group. When the analysis on central nervous system was done separately on the sick and the non_sick group, there was significant difference in the parameter $\theta$/total at Fz and Cz. Although the analysis on autonomic nervous system for all subjects showed the increased activation of sympathetic nervous system, there was no significant difference between the sick and non_sick group. In summary, it is necessary to select the subjects who feel less simulator sickness in order to be accurate sensibility evaluation. The parameters to distinguish between the sick and non_sick group were the change on $\theta$/total and subjective evaluation using SSQ.

• 대한두개안면성형외과학회지
• /
• 제22권1호
• /
• pp.1-10
• /
• 2021

Botulinum toxin type A (BoNT-A), onabotulinumtoxinA (Botox) was approved by the United States Food and Drug Administration for temporary improvement of glabellar lines in patients 65 years and younger in 2002, and has also been used widely for aesthetic purposes such as hyperhidrosis, body shape contouring, and other noninvasive facial procedures. BoNT-A inhibits presynaptic exocytosis of acetylcholine (ACh)-containing vesicles into the neuromuscular junction at cholinergic nerve endings of the peripheral nervous system, thereby paralyzing skeletal muscles. ACh is the most broadly used neurotransmitter in the somatic nervous system, preganglionic and postganglionic fibers of parasympathetic nerves, and preganglionic fibers or postganglionic sudomotor nerves of sympathetic nerves. The scientific basis for using BoNT-A in various cosmetic procedures is that its function goes beyond the dual role of muscle paralysis and neuromodulation by inhibiting the secretion of ACh. Although the major target organs for aesthetic procedures are facial expression muscles, skeletal body muscles, salivary glands, and sweat glands, which are innervated by the somatic or autonomic nerves of the peripheral cholinergic nerve system, few studies have attempted to directly explain the anatomy of the areas targeted for injection by addressing the neural physiology and rationale for specific aesthetic applications of BoNT-A therapy. In this article, we classify the various cosmetic uses of BoNT-A according to the relevant component of the peripheral nervous system, and describe scientific theories regarding the anatomy and physiology of the cholinergic nervous system. We also review critical physiological factors and conditions influencing the efficacy of BoNT-A for the rational aesthetic use of BoNT-A. We hope that this comprehensive review helps promote management policies to support long-term, safe, successful practice. Furthermore, based on this, we look forward to developing and expanding new advanced indications for the aesthetic use of BoNT-A in the future.

• Journal of Chest Surgery
• /
• 제50권2호
• /
• pp.130-132
• /
• 2017

Harlequin syndrome is a rare disorder of the sympathetic nervous system characterized by unilateral facial flushing and sweating. Although its etiology is unknown, this syndrome appears to be a dysfunction of the autonomic nervous system. To the best of our knowledge, thus far, very few reports on perioperative Harlequin syndrome after thoracic surgery have been published in the thoracic surgical literature. Here, we present the case of a 6-year-old patient who developed this unusual syndrome following the resection of a posterior mediastinal mass.

• 대한의용생체공학회:학술대회논문집
• /
• 대한의용생체공학회 1997년도 추계학술대회
• /
• pp.464-467
• /
• 1997

In this study, ECG was recorded during sleep patients with obstructive sleep apnea. We detecte(heart rate variability) signal from the ECG wa QRS detection algorithm. And we observed HRV by the power spectrum density using autoregr modeling. The experimental results were analysis sleep stage 1, sleep stage 2, sleep stage 3, sleep s sleep stage REM. In experimental result, the PSD with obstructive sleep apnea patients was distributed low frequency band except sleep step 4. These effect means that the sympathetic nervous system affected the sleep stage 1, 2, REM and the parasympathetic nervous system affected the sleep stage 3, 4 with obstructive sleep apnea patients.

• 한국정밀공학회:학술대회논문집
• /
• 한국정밀공학회 2006년도 춘계학술대회 논문집
• /
• pp.641-642
• /
• 2006

The purpose of this work is to investigate the effect of work load on heart rate variability (HRV) which is widely used marker of the autonomic nervous system activity. Average heart rate, rating of perceived exertion, and the power spectrum of heart rate variability were investigated in seven healthy males during exercise at various work loads. The subjects were divided into two groups according to the average heart rate during exercise, group 1 with lower heart rate and group 2 with higher heart rate. HF component showed decrease followed by increase with workload. Accordingly, the LF/HF ratio showed increase followed by decrease with workload. The peak in LF/HF ratio of group 1 was at the lower workload than that of group 2.