• Journal of Physiology & Pathology in Korean Medicine
• /
• v.34 no.2
• /
• pp.88-96
• /
• 2020

Stauntonia hexaphylla (SH) and Vaccinium bracteatum (VB) are herbal extracts widely used in food and traditional herbal medicine, and have the ability to perform a wide range of biological activities. We aimed to investigate the effects of the SH and VB combination (SHVB) on mice models of chronic restraint stress (CRS) and pentobarbital-induced sleeping behaviors to elucidate its possible mechanisms of action. CRS-exposed mice treated with SHVB showed significantly decreased immobility time, increased swimming and climbing times in the forced swim test (FST), and increased locomotor activity in the open field test (OFT). SHVB decreased serum CORT levels, but enhanced brain monoamine neurotransmitters. SHVB significantly decreased the sleep latency and increased total sleep duration in pentobarbital-induced sleeping behavior in mice. SHVB showed inhibitory effect on 5-HT_2A receptor-mediated ERK1/2 phosphorylation. These results suggest that SHVB has antidepressant and hypnotic effects by regulating the 5-HT_2A receptor.

• Development and Reproduction
• /
• v.20 no.2
• /
• pp.81-90
• /
• 2016

The effect of sudden changes of water temperature (WT) on the survival rate and physiological responses of the red spotted grouper (Epinephelus akaara) were examined by manipulating WT control system for 9 days. Experimental condition was divided in two different regimes at low (from $10^{\circ}C$ to $4^{\circ}C$, decreased $1^{\circ}C/d$) and high (from $28^{\circ}C$ to $34^{\circ}C$, increased $1^{\circ}C/d$) WT. Survival rate of experimental fishes were observed, and determined the changes of hematological characteristics by analyzing plasma levels of cortisol, glucose, total protein, and electrolytes ($Na^+$, $Cl^-$, $K^+$). No mortality was observed until low WT $6^{\circ}C$ (144 h) and high WT $32^{\circ}C$ (96 h), and 100% mortality was observed at low WT $4^{\circ}C$ (216 h) and high WT $35^{\circ}C$ (171 h). Plasma levels of cortisol and glucose increased rapidly as decreasing WT, and the loss of swimming ability and respiration response was observed at low WT $7^{\circ}C$ and high WT $34^{\circ}C$ conditions.

• The Journal of the Korean dental association
• /
• v.53 no.9
• /
• pp.602-609
• /
• 2015

The aim of this document is to evaluate the effect of bite balance on physical fitness and motor capacity to determine the importance of the occlusal stability as a possible action mechanism of occlusal appliance including mouthguards on physical performances. We all remember that day when the prominent athlete was in the news wearing a mouthguard to improve human athletic performance. I once had investigated the determinants of athletic performance in all sorts of sports. Most of the studies had overinterpretation of results and lack of evidence to support the information. However, I discovered great expectations for new possibility in this field and settled for a more academic approach to this intriguing subject. The followings are some examples of the subject 1. Archers who wore occlusal appliances to increase the vertical dimension of occlusion by 2~3mm increased their ability to focus and to maintain good sense of balance. Their accuracy rate has been improved. The appliance was made of acrylic resin (a type of plastic). 2. Canoe players who wore occlusal appliances to increase the vertical dimension of occlusion by 5mm surpassed longtime competitor and won the race with 10 seconds gap. 3. A cycle rider who wore an occlusal appliance to treat his malocclusion surpassed his old record from 10.8 seconds to 10.3 seconds. His muscle reflexes (anaerobic exercise) and endurance (aerobic exercise) has been enhanced. 4. Occlusal appliances had a good effect on athletic performance in most sports such as swimming, diving, and weightlifting. As for the clenching on dentition, people clench their teeth when they push their physical and mental limits during sports activities. Clenching can be induced by physical exertion when maximum muscle strength is retained and this is similarly found in different types of exercises. In addition, restraint of respiratory function is observed. Therefore, creating a occlusal balance with occlusal appliance or mouthguard promoted a favorable influence when an athlete clenches.

• Proceedings of the Korea Water Resources Association Conference
• /
• 2007.05a
• /
• pp.527-531
• /
• 2007

하천내에서 작은 물고기의 국지적인 회유 또는 이동 습성은 먹이를 구하고, 산란 및 성장과 집단에서 분산하고, 위험으로부터 도피하는 것에 밀접한 연관이 있다. 하천의 합류부와 연결부에 제방(levee), 도로(road) 등이 설치되는 경우 일반적으로 암거형태의 인공수로로 상 하류를 연결되는데, 암거내 수리특성상 평수시 저유량, 고유속, 저수심의 수리특성을 보인다. 이러한 수리특성은 물고기가 이동하는데 장애(barrier)가 되어 생태적으로 하천내 종다양성 감소와 일부 어종의 멸종을 초래한다. 어도 설치시 설계기준에서 가장 주목할 부분은 어도를 이용할 대상어종의 범위와 유영능력이다. 하천설계기준(2005, 한국수자원학회)에서 제시된 물고기의 유영능력은 대부분 국외 어종을 대상으로 외국에서 실험한 결과를 이용하고 있다. 그러므로 이러한 기준이 국내 어종에 대해 적합한지에 대한 검토가 필요하다. 본 실험의 목적은 국지회유성인 피라미와 각시붕어가 인공수로를 통과할 때의 유영행동 중 소상성공율과 유영속력을 평가하고자 함이다. 유영행동의 실험방법은 Brett(1967)에 의해 제안된 2가지 방법인 증진유속방법과 고정유속 방법중에서 물고기의 이동경로와 소상능력을 확인하기에 용이한 고정유속방법을 사용하였다. 또한, 효과적인 실험을 위해 실험어종(피라미 100마리, 각시붕어 100마리)이 실험 중에 최적의 건강상태를 유지할 수 있도록 물고기의 적응 기간(24시간)과 실험 중 휴식기간을 두었다. 실험결과 체형이 방추형(fujiform)인 피라미의 경우 평균유속 $0.7{\sim}0.8m/s$구간에서 소상성공율이 61%에서 26%로 급격하게 하락하는 현상이 나타났다. 그리고 측편형(compressiform)의 체형을 가진 각시붕어의 경우 평균유속 0.4m/s에서 소상성공율이 25%로 나타났으며 그 이상의 유속에서는 10%이하로 나타났다. 실험어종의 이동경로를 분석한 결과 대부분 수로바닥에 밀착하여 최저유속구간을 이용하여 이동하는 것으로 나타났으며, 이동경로의 지점유속은 평균 유속의 70%정도로 나타났다. 실제 하천에 설치된 인공수로가 생태통로의 기능을 유지하기 위해서는 평상시 수리특성이 대상어종의 유영능력을 초과하지 않도록 설계되어야 한다. 특히, 하천에 설치된 인공수로의 길이가 $5{\sim}10m$정도일 경우라면 피라미의 소상 가능성을 50% 이상 확보하기 위해서는 평수시 설계유속이 0.7m/s를 초과하지 않아야 할 것으로 판단된다.

• Journal of Ginseng Research
• /
• v.30 no.1
• /
• pp.15-21
• /
• 2006

This study was carried out to determine the antioxidative activities of tissue cells of mouse kidney isolated from mice fed with different formulation of drinks. The swimming ability of experimental groups without caffeine showed the same pattern, but caffeine group decreased slightly. Superoxide dismutase(SOD) and catalase(CAT) activities of caffeine-containing groups were decreased significantly, but the control and ginseng-containing groups were increased. Hydroperoxide contents did not increase significantly all experimental groups. Hydroperoxlde contents of the control and ginseng-containing groups were similar, but caffeine-containing groups increased. Compared to the control and ginseng-containing groups, lipid peroxidation level and protein contents in caffeine-containing groups were decreased significantly. In conclusion, the antioxidative activities of mouse kidney isolated from mice fed with ginseng-containing products was increased slightly.

• Physical Therapy Rehabilitation Science
• /
• v.6 no.2
• /
• pp.77-82
• /
• 2017

Objective: Swimming and water-based exercise (WE) programs can provide vigorous physical activity in a fun and a motivating environment. The properties of water, may make it easier for children with cerebral palsy (CP) to move and to participate in an WE program. The aims of this study was to evaluate the effect of WEs on postural control in children with spastic CP. Design: Quasi-experimental design (one group pretest-posttest design). Methods: Twenty preschoolers with spastic CP participated in this study. Prior to the application, sufficient warm-up training was performed to allow the subjects to adapt to the water. Afterwards, three different types of underwater leg exercises for the flexor, extensor, and adductor/abductor of muscles of the lower limb were performed. The WE program lasted during 8 weeks, with one-40 minute sessions per week (8 training session). The usual care was performed during the training session. The Korean-trunk control measurement scale (K-TCMS) and weight distribution variability (difference of both Fz) were measured before and after training session. Results: According to the results, the K-TCMS scores of the three sub-levels, including static sitting, dynamic sitting, and dynamic reaching, was significantly increased after the training session (p<0.05). Also, the weight distribution variability was significantly decreased after 8 weeks (p<0.05). Conclusions: We suggest that WEs may improve the postural control ability in children with spastic CP. Furthermore, we support the need for additional research on the effect of WE on gait or activity of daily living performance with a control group included.

• Journal of muscle and joint health
• /
• v.21 no.2
• /
• pp.97-105
• /
• 2014

Purpose: The purpose of this study was to identify the effects of an aquatic exercise program on physical fitness, body composition, and gait characteristics using trunk and pelvic angle in women living in urban fringe area. Methods: An aquatic exercise program consists of exercise in a swimming pool and self-help group activity with 16 women living in urban fringe (mean age: 63 years) for 8 weeks (twice a week for 2 hours). Physical fitness, body composition, trunk and pelvic angle using 2D video motion analyzer, and a questionnaire including socio-demographic variables were measured from July to August, 2013. Data were analyzed using a paired t-test with the SPSS/WIN 18.0 program. Results: At the end of 8 weeks intervention, there were significant decreases on body weight (p=.025), body fat (p=.030) and BMI (p=.011). There were significant increases on muscle strength (p=.001) and flexibility (p=.015). Trunk angle was significantly improved, which means participants less moved their body from side to side when they walked (p=.001). Conclusion: From this results, the aquatic exercise program could be an effective nursing intervention to improve physical fitness, body composition, and gait ability for women living in urban fringe area.

• Development and Reproduction
• /
• v.21 no.4
• /
• pp.399-406
• /
• 2017

This study was conducted to investigate egg development and larvae morphological development of catfish and to provide basic data to clarify the genetic relationship with Siluriformes fish. The mother fish that was used in this study was caught in the stream of Nakdong River in Uiseong-gun, Gyeongbuk. The temperature range of the breeding was $23.0-25.0^{\circ}C$ (mean $24.0{\pm}1.0^{\circ}C$) and egg size was 1.62-1.70 mm (mean $1.66{\pm}0.05$, n=30). Eggs of catfish began hatching at 54 hours and 40 minutes after fertilization. Immediately after hatching, the total length of larvae was 3.60-3.65 mm (mean $3.62{\pm}0.03$, n=5) and had an egg yolk without swimming ability. On the third day after hatching, the larvae at the medium stage was 8.00-8.65 mm (mean $8.32{\pm}0.45$) in total length, and two pairs of whiskers formed around the mouth were elongated. On the 12th day after hatching, the larvae at the juvenile stage was 16.5-17.0 mm (mean $16.7{\pm}0.35$) in total length, and the stem of each fin was in the range, and the juvenile at this period was morphologically similar to the mother fish.

• Biomolecules & Therapeutics
• /
• v.27 no.2
• /
• pp.160-167
• /
• 2019

Depression is a major mood disorder. Abnormal expression of glial glutamate transporter-1 (GLT-1) is associated with depression. Schisantherin B (STB) is one bioactive of lignans isolated from Schisandra chinensis (Turcz.) Baill which has been commonly used as a traditional herbal medicine for thousands of years. This paper was designed to investigate the effects of STB on depressive mice induced by forced swimming test (FST). Additionally, we also assessed the impairment of FST on cognitive function in mice with different ages. FST and open field test (OFT) were used for assessing depressive symptoms, and Y-maze was used for evaluating cognition processes. Our study showed that STB acting as an antidepressant, which increased GLT-1 levels by promoting PI3K/AKT/mTOR pathway. Although the damage is reversible, short-term learning and memory impairment caused by FST test is more serious in the aged mice, and STB also exerts cognition improvement ability in the meanwhile. Our findings suggested that STB might be a promising therapeutic agent of depression by regulating the GLT-1 restoration as well as activating PI3K/AKT/mTOR pathway.

• Korean Journal of Fisheries and Aquatic Sciences
• /
• v.56 no.4
• /
• pp.558-568
• /
• 2023

The spatio-temporal distribution of the sand crab Ovalipes punctatus larvae was investigated in the Korean waters in 2019. Sea surface temperature (SST) was the lowest in February and highest in September. Sea surface salinity (SSS) was the lowest in September and highest in March. Further, sea surface chlorophyll a (SSC) was the highest in September. Larvae were distributed in the South Sea and coastal area of Jeju Island from April to June, and the abundance was the highest in May. The spatio-temporal distribution analysis suggested that larval groups showed a tendency to be dispersed over a wider area as the larvae developed, due to the increase in their swimming ability. The correlation analysis between environmental factors and larval density suggested that larvae appeared in the SST range 11.8-20.9℃ and SSS range 31.5-35.3 psu. The Megalopal stage appeared in a wider range of SST and SSS than other larval stages, possibly due to the increased environmental tolerance before settlement. Results of redundancy analysis (RDA) and Spearman's rank correlation analysis between the larval density by developmental stages and the environmental factors suggested that SST showed a positive correlation and SSC showed a negative correlation in the later stage.