• 대한수의학회지
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• 제24권1호
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• pp.31-35
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• 1984

The hemoglobin phenotype and the gene frequencies of 44 Formosan deer(Cervus nippon) in Kyung-Gi area were examined by using cellulose acetate and starch gel electrophoresis. 1. The method of cellulose acetate electrophoresis was simplier, more clear and preserative than starch gel electrophoresis. 2. The hemoglobin phenotype was appeared 3 types as $Hb^F$ $Hb^{FS}$ and $Hb^S$. The frequencies of appearance were $Hb^F$ 47.7%, $Hb^{FS}$ 47.7% and $Hb^S$ 4.5%, respectively. 3. The genetic factors of hemoglobin were observed as $Hb^F$ and $Hb^S$ and the rates of gene frequencies were 71.6% and 28.4%, respectively.

• Communications for Statistical Applications and Methods
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• 제25권5호
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• pp.523-544
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• 2018

Bivariate distributions play a fundamental role in survival and reliability studies. We consider a regression model for bivariate survival times under right-censored based on the bivariate Kumaraswamy Weibull (Cordeiro et al., Journal of the Franklin Institute, 347, 1399-1429, 2010) distribution to model the dependence of bivariate survival data. We describe some structural properties of the marginal distributions. The method of maximum likelihood and a Bayesian procedure are adopted to estimate the model parameters. We use diagnostic measures based on the local influence and Bayesian case influence diagnostics to detect influential observations in the new model. We also show that the estimates in the bivariate Kumaraswamy Weibull regression model are robust to deal with the presence of outliers in the data. In addition, we use some measures of goodness-of-fit to evaluate the bivariate Kumaraswamy Weibull regression model. The methodology is illustrated by means of a real lifetime data set for kidney patients.

• 한방안이비인후피부과학회지
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• 제21권1호
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• pp.133-138
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• 2008

Objectives : We already reported the effectiveness of this treatment method(electroacupuncture at oculomotor muscles) at the adult and young idiopathic paralytic strabismus patients and Miller-Fisher syndrome. Then I explored the possibility for improvement of the traumatic injury paralytic strabismus case. Methods : I treated the case by using the electroacupuncture at both paralytic lateral rectus muscle lesions. The case was treated almost daily and every treatment was enforced 10 minutes. I use the PG-306 electra-acupuncture products(Suzuki Iryoki Co. Japan) and apply the low consequence wave of 1-8Hz. Results : We gained good results from the case and not observed any sides effect or compliant. So I hope to apply this treatment for traumatic and post-operative nerve injury cases and am sure to make the treatment protocol for them in the future.

• 대한용접접합학회:학술대회논문집
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• 대한용접접합학회 2005년도 춘계학술발표대회 개요집
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• pp.393-395
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• 2005

The bonding for Aluminum and Copper in the air is investigated in this study. This bonding method does not include the special process of removing aluminum oxide films. In case of this bending, each metal Is heated at bonding temperature where is above eutectic temperature of Al-Cu system and below melting point of Aluminum. The liquefaction around the bonding surface occurs after the diffusion at solid state of each metal. This phenomenon is predicted by the temperature range above eutectic temperature of Al-Cu equilibrium phase diagram.

• 한국분말야금학회:학술대회논문집
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• 한국분말야금학회 2006년도 Extended Abstracts of 2006 POWDER METALLURGY World Congress Part 1
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• pp.28-29
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• 2006

High-Speed Centrifugal Compaction Process (HCP) is a wet compacting method, in which powders are compacted under a huge centrifugal force. The HCP was well applied to small alumina specimens, but the compact easily cracked when we applied the HCP to other materials. We clarified how the cracks introduced and found that the formation of such a flow pattern was related to the Colioli's force in the centrifugal field.

• 한국분말야금학회:학술대회논문집
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• 한국분말야금학회 2006년도 Extended Abstracts of 2006 POWDER METALLURGY World Congress Part 1
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• pp.24-25
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• 2006

High-Speed Centrifugal Compaction Process is one of slip-using compacting method originally developed for processing of oxide ceramics. In this study, we apply the HCP to ultra-fine (0.1 micron) WC powder. Organic liquid of heptane was chosen as dispersing media to avoid possible oxidation of WC. The mixing apparatus was a key to obtain dense compacts. Only the slips mixed by high energy planetary ball mill were packed up to 55% by the HCP, and sintered to almost full density at 1673 K without any sintering aids. This sintered compact marked Vickers hardness of Hv 2750 at maximum.

• 대한의용생체공학회:의공학회지
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• 제11권1호
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• pp.13-18
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• 1990

Frequency responses of ambulatory electrocardiogram systems were measured. Phase shift was assessed by our improved Wagner's method. The characteristics of the systems were found much worse than that of ordinary ECG equipment both in gain and phase responses. The decay of -3dB in amplitude observed in 0.2Hz and the lead of 45 dog in phase was observed in 0.6Hz. In order to investigate which of these 2 responses play major role in generating false S -T deviation, mathe- matical filters were Composed in a computer and actual ECGs were fed. The false S-T deviation were found to be caused mostly by enormous lead in phase, and then, the compensation circuit to diminish the lead in phase was inserted in the commercial systemes. The compensated systems showed no false deviation in S-T segment.

• Journal of Microbiology and Biotechnology
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• 제22권9호
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• pp.1279-1287
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• 2012

We established an efficient transformation method for thermophile Geobacillus kaustophilus HTA426 using conjugative transfer from Escherichia coli of host-mimicking plasmids that imitate DNA methylation of strain HTA426 to circumvent its DNA restriction barriers. Two conjugative plasmids, pSTE33T and pUCG18T, capable of shuttling between E. coli and Geobacillus spp., were constructed. The plasmids were first introduced into E. coli BR408, which expressed one inherent DNA methylase gene (dam) and two heterologous methylase genes from strain HTA426 (GK1380-GK1381 and GK0343-GK0344). The plasmids were then directly transferred from E. coli cells to strain HTA426 by conjugative transfer using pUB307 or pRK2013 as a helper plasmid. pUCG18T was introduced very efficiently (transfer efficiency, $10^{-5}-10^{-3}\;recipient^{-1}$). pSTE33T showed lower efficiency ($10^{-7}-10^{-6}\;recipient^{-1}$) but had a high copy number and high segregational stability. Methylase genes in the donor substantially affected the transfer efficiency, demonstrating that the host-mimicking strategy contributes to efficient transformation. The transformation method, along with the two distinguishing plasmids, increases the potential of G. kaustophilus HTA426 as a thermophilic host to be used in various applications and as a model for biological studies of this genus. Our results also demonstrate that conjugative transfer is a promising approach for introducing exogenous DNA into thermophiles.

• Communications for Statistical Applications and Methods
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• 제24권6호
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• pp.627-640
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• 2017

A common interest in gene expression data analysis is to identify genes that present significant changes in expression levels among biological experimental conditions. In this paper, we develop a Bayesian approach to make a gene-by-gene comparison in the case with a control and more than one treatment experimental condition. The proposed approach is within a Bayesian framework with a Dirichlet process prior. The comparison procedure is based on a model selection procedure developed using the discreteness of the Dirichlet process and its representation via Polya urn scheme. The posterior probabilities for models considered are calculated using a Gibbs sampling algorithm. A numerical simulation study is conducted to understand and compare the performance of the proposed method in relation to usual methods based on analysis of variance (ANOVA) followed by a Tukey test. The comparison among methods is made in terms of a true positive rate and false discovery rate. We find that proposed method outperforms the other methods based on ANOVA followed by a Tukey test. We also apply the methodologies to a publicly available data set on Plasmodium falciparum protein.

• Journal of Computational Design and Engineering
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• 제2권2호
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• pp.96-104
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• 2015

Aluminum die casting is an important manufacturing process for mechanical components. Die casting is known to be more accurate than other types of casting; however, post-machining is usually necessary to achieve the required accuracy. The goal of this investigation is to develop machining- free aluminum die casting. Improvement of the accuracy of planar and cylindrical parts is expected by correcting metal molds. In the proposed method, the shape of cast aluminum made with the initial metal molds is measured by 3D scanning. The 3D scan data includes information about deformations that occur during casting. Therefore, it is possible to estimate the deformation and correction amounts by comparing 3D scan data with product computer-aided design (CAD) data. We corrected planar and cylindrical parts of the CAD data for the mold. In addition, we corrected the planar part of the metal mold using the corrected mold data. The effectiveness of the proposed method is demonstrated by evaluating the accuracy improvement of the cast aluminum made with the corrected mold.