• 대한수의학회지
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• 제34권4호
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• pp.735-744
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• 1994

미성숙 래트의 외경정맥에 카테타를 장착하고, 다음날(28일령) 대조군에는 4IU, 다배란처치군에는 20IU의 PMSG를 피하 주사하였다. 각 실험동물은 혈중의 LH농도 변화를 측정하기 위하여 PMSG 투여직전(0시간), 투여후 12시간, 그 이후 6시간 간격으로 혈액을 채취하고 72시간에 희생시켰다. 그 결과 다배란용량의 PMSG 투여는 먼저 배란반응을 대조군에 비하여 4.0배나 현저하게(P<0.05) 증가시켰다. 또한 난관으로부터 회수된 다배란난자는 상당히 다른 감수분열상의 핵성숙도를 나타내었는데, 즉 prophase I이 14.7%, anaphase I이 36.2%, telophase I이 10.3%, metaphase I/II가 32.4%이었다. 그러나 대조군의 래트에서는 대다수(94.0%)의 난자가 한결같이 metaphase II상을 보였다. 그리고 혈청 LH농도는 radioimmunoassay(RIA)에 의하여 결정되었는데, 먼저 두군 모두 두개의 분명한 peak을 가진 경시적 변화관계를 보였다. 즉 이들 두군에 있어서 LH농도변화는 0-18시간대에 처음으로 완만한 증가와 54-60시간대에 두번째의 급격한 증가(surge)를 보였다. 그러나 두군간에 LH농도의 크기는 현저하게 달라, 다배란처치군의 동물에 있어서는 두번째의 LH peak에 앞서 전반적인 LH농도가 대조군보다 현저하게(P<0.001) 높았으나, FMSG 투여후 60시간에 일어나는 peak에 있어서는 LH농도가 대조군보다 현저하게(P<0.001) 54%나 낮았다. 덧붙여 두 peak간의 증가폭은 대조군에 비하여 다배란처치군에서 훨씬 낮았다. 다배란래트에 있어서 54시간 이전에 최초로 연속적인 증가를 보인 고농도의 혈청 LH는 실제적으로 투여된 PMSG와 측정시의 LH항체와의 교차반응(cross-reaction)에 의한 결과로 판명되었고, 한편 54시간과 60시간에 있어서 두번째로 급격한 증가를 보인 혈청 LH는 주로 뇌하수체로부터 분비되는 내재성 LH surge에 의한 것으로 사료된다. 본 연구 결과는 PMSG투여된 래트에 있어서 혈청 LH의 경시적인 변화상 및 그 특징을 정의한다. 그리고 전체적인 연구결과는 첫째, 다배란용량의 PMSG투여에 따른 배란반응의 증가가 주로 PMSG 자체에 함유된 고나도트로핀 작용과 연관이 있고, 둘째, 미성숙 또는 부동기적 핵성숙을 보이는 다배란난자의 회수는 최초의 혈청 LH의 연속적인 증가 및 이의 연이은 감퇴로 특징지워지는 LH활동도의 비정상적 혈중변화에 기인함을 시사한다.

• Journal of Pharmaceutical Investigation
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• 제33권1호
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• pp.67-71
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• 2003

Drug excipients are material used in the formulation of pharmacologically active drugs. They have a variety of roles including dilutents/fillers/bulking agents, binders/adhesives, propellant, disintegrants, lubricants/dlidants, colors, flavors, coating agents, polising agents, fragrance, sweeteening agent, polymers and waxes. Excipient should be inert or inactive and does not interfere with the test. Nowadays within industry there has been a recent surge of interest in novel excipient for novel dosage forms. The purpose of the review is to introduce the administration systems of drug excipient about kinds, matters to be attended to change of excipients.

• 유공압시스템학회논문집
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• 제7권2호
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• pp.19-26
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• 2010

The typical trunk lid system for vehicle is composed of a hinge having 4-bar link and gas lifter. Here, the energy regenerative brake of hydraulic driven systems is applied to the tail gate system for vehicle and removed the gas lifter. The new tail gate system is composed of a hydraulic pump by electric motor, a hydraulic motor, four check valves, an accumulator, a relief valve and a directional control valve. The dynamic characteristics of the hydraulic motor system, such as the surge pressure and response time, are investigated in both brake action and acceleration action. The capacity selection method of accumulator by mathematical model is based upon trial and error approach and computer simulation by AMEsim software is carried out.

• 한국정밀공학회지
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• 제5권2호
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• pp.33-42
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• 1988

In a large scale oil hydraulic system having repeatedly operated actuator, such as a large scale forging press, pressure surges often due to the recombination of oil column in a return line attached to the downstream side of a directional control valve. Expecially, the pressure surges appear very severe ones at a certain valve operating frequency. These pressure surges restrict the operating frequency of the hydraulic system. But related reports on the above mentioned phenomenon are rarely to be found. In this study, therefore, the authors investigate the exact reason why such severe pressure surges occur at a certain range of valve operating frequency. The study is performed by experiment and numerical computation on the relationship between pressure surges and valve operating frequency.

• Journal of Mechanical Science and Technology
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• 제15권2호
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• pp.232-238
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• 2001

Fast Fourier Transformation is employed to convert the head variation of a pipeline in the time domain to the amplitude of the frequency domain. Applying method of characteristics to a pipeline provides a significant frequency range for a surge introduced from the valve modulation. Inverse Fast Fourier Transformation and a Finite Impulse Response Filter can be used to remove any possible noise existing from the significant frequency range of an unsteady condition. A filtered signal shows higher potential for the inverse calculation of leakage detection than the noise-added signal does. The respective performances of Inverse Fast Fourier Transformation and a Finite Impulse Response Filter are compared in terms of leakage detection capability. Characteristics of the frequency range for multiple leakages were investigated to validate the effectiveness of the noise control method in the frequency domain.

• 대한기계학회논문집
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• 제16권2호
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• pp.191-199
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• 1992

This paper presents in experimental study of the dynamic internal pressure within an oil hydraulic vane pump. The measurements of the dynamic internal pressures near the vane of a pressure balance type of an oil hydraulic vane pump with intravanes has been made to provide the essential information for the study of the pump dynamics and control, the pump design and the analysis of tribological problems in the sliding components. The influences of the discharge pressure and rotating speed of the vane on the dynamic pressure in four chambers surrounding a vane have been investigated. The results indicate that the surge pressures of the chambers at the instant moment of discharge and closure are affected by the rotating speed. The pressure in the intravane chamber maintains almost constant values, which remarkably effects the pulsating discharge pressure.

• 한국건축시공학회:학술대회논문집
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• 한국건축시공학회 2012년도 춘계 학술논문 발표대회
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• pp.211-212
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• 2012

Over the years, the recovery of the domestic construction market, which does not appear on the reverse, but rather due to a surge of construction materials cost of the construction sector is experiencing greater difficulties. Cement raw materials in the manufacturing process, if some of the waste recycling, cites quality control for products and measures for the thorough management is needed. In this study, three companies of the past four years in the production of cement against doejin physical performance test results conducted yearly and seasonal trends by analyzing changes in the years to review the cement for cement to utilize as a basis for management points is.

• Archives of Plastic Surgery
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• 제40권3호
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• pp.263-266
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• 2013

Bleeding, is one of the most common postoperative complications after palatoplasty in patients with cleft palate. The purpose of this article is to present our experience using a Foley catheter balloon for perioperative palatoplasty bleeding management. A retrospective data analysis was performed for all cases of palatoplasty performed by the author from 1999 to 2012 that experienced postoperative hemorrhage. These patients were managed by utilizing posterior nasal compression with a Foley catheter balloon for the period 2006 to 2012. We have compared two methods (we use before 2006 the reoperative method) with regards to the later development of palatal fistulae and cases with reoperative hemostasis. The study found no statistically significant differences between the conventional and proposed method in relation to the development of palatal fistulae (P=0.7). These findings suggest that nasal packing using a Foley balloon is a safe and effective method for postoperative bleeding control after palatoplasty in patients with cleft palate.

• 물과 미래
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• 제12권2호
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• pp.49-55
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• 1979

본 연구는 관수로내의 부정류 즉 펌푸모터의 시동, 정지 및 발브 조절시에 압력관수로에 나타나는 급변류의 현상, 특히 수격작용의 해석을 Computer에 의해 자동해석하는 방법을 강구하였다. 따라서 사용되는 관수로가 펌푸, 관망, 터널, 조압수조, 분기관, 저수지, 폐단관 및 발브장치를 갖는 일련의 관수로내에 일어나서 전자계산기를 사용하면 송수 또는 배수관로 설계에 있어 설계자의 시간과 노력을 감소하고 정확한 결과를 얻을 수 있는 장점이 있다.

• 대한전기학회:학술대회논문집
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• 대한전기학회 1998년도 하계학술대회 논문집 E
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• pp.1578-1582
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• 1998

The ground potential rise generated by the switching surge or lightning stroke may be dangerous to personnel and cause damage to electronic control parts. For a first step to the transient performance analysis. high frequency impedances of grounding grids have been calculated and discussed. Grounding grids include 7 square grids from $10m{\times}10m$ to $80m{\times}80m$. The high frequency current was injected into the center and a corner of the grounding grid. The calculation results indicate that the impedance of the grounding grid is significantly influenced by frequency and the point of injection of the current. and the effective radius of a large grounding grid may be represented in $15{\sim}20m$.