• Journal of Korea Water Resources Association
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• v.50 no.6
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• pp.419-427
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• 2017

In mountainous rivers, the drag force acting on cobbles abundant in the riverbed surface is important in predicting behavior and response of the river. However there is little research for the drag coefficients of cobbles. This paper is to carry out the experiments for drag force of cobble and analyze the relation between the cobble shape and the drag coefficient. The effects of the shape factor on the drag coefficients $C_D$ when the long axis or the short axis of the cobbles are parallel to the direction of flow velocity were analyzed. The coefficient of drag force increased with the nominal diameter Reynolds number $R_{ep}$. The drag coefficients are greater in short axis than long axis. The coefficient of determination of the relation between $C_D$ and $R_{ep}$ is greater in long axis than short axis. This means that the drag forces acting on the irregularly-shaped cobbles depend on the axis. A change of the drag force distribution has brought about the alternative swing of cobbles. For $R_{ep}$ > 12,000, the amplitude of the swing has been increased sharply and especially was greater in short axis than long axis.

• Journal of Electrical Engineering and Technology
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• v.10 no.3
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• pp.1144-1153
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• 2015

The resonant mechanism of reradiation interference (RRI) over 1.7MHz from power transmission lines cannot be obtained from IEEE standards, which are based on researches of field intensity. Hence, the resonance is ignored in National Standards of protecting distance between UHV power lines and radio stations in China, which would result in an excessive redundancy of protecting distance. Therefore, based on the generalized resonance theory, we proposed the idea of applying model-based parameter estimation (MBPE) to estimate the generalized resonance frequency of electrically large scattering objects. We also deduced equation expressions of the generalized resonance frequency and its quality factor Q in a lossy open electromagnetic system, i.e. an antenna-transmission line system in this paper. Taking the frequency band studied by IEEE and the frequency band over 1.7 MHz as object, we established three models of the RRI from transmission lines, namely the simplified line model, the tower line model considering cross arms and the line-surface mixed model. With the models, we calculated the scattering field of sampling points with equal intervals using method of moments, and then inferred expressions of Padé rational function. After calculating the zero-pole points of the Padé rational function, we eventually got the estimation of the RRI’s generalized resonant frequency. Our case studies indicate that the proposed estimation method is effective for predicting the generalized resonant frequency of RRI in medium frequency (MF, 0.3~3 MHz) band over 1.7 MHz, which expands the frequency band studied by IEEE.

• Asian Pacific Journal of Cancer Prevention
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• v.16 no.13
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• pp.5285-5288
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• 2015

Background: Hepatitis B virus (HBV) infection has been reported to be associated with inferior prognosis in hepatocellular and pancreatic carcinoma cases, but has not been studied with respect to non small cell lung cancer (NSCLC). The purpose of this study was to investigate the prognostic significance of HBV infection in advanced NSCLC patients. Materials and Methods: A retrospective cohort of 445 advanced NSCLC patients was recruited at our hospital from January 1, 2003 until August 30, 2014. Serum HBV markers were tested by enzyme-linked immunosorbent assay. COX proportional hazards analysis was used to evaluate associations of HBV infection with overall survival (OS). Results: Of 445 patients who were qualified for the study, 68 patients were positive for HBsAg, also considered as HBV infection. Patients in HBsAg negative group were found to have better OS (12.6 months [12.2-12.9]) than those in HBsAg positive group (11.30 months [10.8-11.9]; p=0.001). Furthermore, COX multivariate analysis identified HBV infection as an independent prognostic factor for OS (HR 0.740 [0.560, 0.978], p=0.034). Conclusions: Our study found that HBsAg-positive status was an independent prognostic factor for OS in patients with advanced NSCLC. Future prospective studies are required to confirm our findings.

• Parasites, Hosts and Diseases
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• v.60 no.2
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• pp.117-126
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• 2022

Cystatin, a cysteine protease inhibitor found in many parasites, plays important roles in immune evasion. This study analyzed the molecular characteristics of a cystatin from Fasciola hepatica (FhCystatin) and expressed recombinant FhCystatin (rFhcystatin) to investigate the immune modulatory effects on lipopolysaccharide-induced proliferation, migration, cytokine secretion, nitric oxide (NO) production, and apoptosis in mouse macrophages. The FhCystatin gene encoded 116 amino acids and contained a conserved cystatin-like domain. rFhCystatin significantly inhibited the activity of cathepsin B. rFhCystatin bound to the surface of mouse RAW264.7 cells, significantly inhibited cell proliferation and promoted apoptosis. Moreover, rFhCystatin inhibited the expression of cellular nitric oxide, interleukin-6, and tumor necrosis factor-α, and promoted the expression of transforming growth factor-β and interleukin-10. These results showed that FhCystatin played an important role in regulating the activity of mouse macrophages. Our findings provide new insights into mechanisms underlying the immune evasion and contribute to the exploration of potential targets for the development of new drug to control F. hepatica infection.

• Journal of the Korean institute of surface engineering
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• v.44 no.1
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• pp.21-25
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• 2011

This test focuses on the correlation between the lubrication, ductility and strength through the change of nut lubricant which decides joining angle for A490 bolt sets required in the AASHTO (American Association of State Highway & Transportation Officials). Because the lubrication of high tension bolt, nut, washer sets becomes an important factor to ductility and joining load, the quality improvement is required for improving reliability and securing enough lubrication of maker and user. This study examines the quality characteristics required in the specification through tests because only this standard specifies joining quality in the extreme conditions (as much about two times of the joining angle on site as normal condition). Moreover, this study is limited to the test on joining axial force required in the AASHTO for the three nut lubrication conditions of A490 bolt set. It is concluded that the nuts should be coated or waxed enough for the improvement of the joining axial force and ductility of bolts required in the standards. It is shown that in the case of plain high tension bolt sets, a rust preventing lubricative oil shall be applied and the torque coefficient value for A490 bolt sets should be maintained below 0.175.

• Proceedings of the Membrane Society of Korea Conference
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• 2004.05a
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• pp.94-97
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• 2004

Micro/nano-sized L $a_{0.6}$S $r_{0.4}$Co $O_{3-}$$\delta$/ particles are considered to improve oxygen permeability in highly selective inorganic oxygen separation membrane. A L $a_{0.7}$S $r_{0.3}$G $a_{0.6}$F $e_{0.4}$ $O_{3-}$$\delta$/ membrane with perovskite structure is fabricated by a conventional solid-state reaction. As the oxygen permeation flux of the L $a_{0.7}$S $r_{0.3}$G $a_{0.6}$F $e_{0.4}$ $O_{3-}$$\delta$/ membrane was lower than commercial gas separation membranes, we coated the L $a_{0.6}$S $r_{0.4}$Co $O_{3-}$$\delta$/ particles to enhance the oxygen permeation flux. It has been demonstrated that the effective area of reactive free surface is an important factor in determining the effectiveness of the introduction of coating layer for oxygen permeation. The introduction of micro/nano L $a_{0.6}$S $r_{0.4}$Co $O_{3-}$$\delta$/ particles was very effective for increasing oxygen flux, as the flux was as much as 2 to 6 times higher than that of an uncoated L $a_{0.7}$S $r_{0.3}$G $a_{0.6}$F $e_{0.4}$ $O_{3-}$$\delta$/ membrane.\delta$/ membrane.>/ membrane.brane.

• The Journal of Engineering Geology
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• v.18 no.2
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• pp.177-183
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• 2008

In the study, we carried out a 3-D analysis to assess the influence of groundwater level changes on the slope stability, conducting a series of back-numerical analysis to delineate the critical line of the shear strength of the failure surface of a landslide, and a laboratory test to determine the geo-mechanical properties of soil samples. The analysis result shows that the shear strength determined by the laboratory test was distributed below the critical line of shear strength estimated by back-analysis. Differences between driving and resisting force were also analyzed in groundwater conditions of dry and saturation. It appeared that the stress gets greater towards the slope center of the landslide, and the debris mass moves downwards. According to the analysis, the factor of safety becomes 1 with the rise of foundwater level up to -0.85 m from the slope surface, while the slope tends to stay stable during dry seasons.

• Design & Manufacturing
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• v.11 no.3
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• pp.46-50
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• 2017

Press processing is one of the best machining methods capable of mass production, satisfying dimensional, shape and quality among the methods of processing a metal plate. Among them, Fine blanking is a method of obtaining a precise cross-section such as machining of the shear surface shape. In this research, Using SCP-1 and SHP-1 materials. The deformation behaviors of the material flow affecting the die height of the shear section in accordance with the position of the V-ring in the Fine blanking were compared and analyzed. Result of interpretation, It was confirmed that the force acts on the position where the material flow direction accurately forms the die roll that the material of SCP-1 is at a position of 1.5 mm and the material of SHP-1 is at 2.0 mm. As a result, it was confirmed that the state of fo1111ing the shear surface by the V-ring was excellent. Using analysis results, In the experiment, the height of the die roll was considered by applying The position of the V-ring was 1.5 mm in SCP-1 and 2.0 mm in SHP-1. As a result of comparing the height of the die rolls, the height values of the die rolls were different from each other, It has been considered that the tendency of the die rolls to coincide with each other. It is considered that the difference of the die roll height is caused by the pressure input of the V-ring. In this study, the deformation behavior of the material(In addition to the position of the V-ring, the flow direction of the material depends on the shape of the V-ring and the Indentation amount) is considered to be an important factor in determining die roll height.

• Steel and Composite Structures
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• v.41 no.6
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• pp.831-850
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• 2021

Surface subsidence caused by mining subsidence has an impact on neighboring structures and utilities. In other words, subsurface voids created by mining or tunneling activities induce soil movement, exposing buildings to physical and/or functional destruction. Soil-structure is evaluated employing probability distribution laws to account for their uncertainty and complexity to estimate structural vulnerability. In this study, to investigate the displacement field and surface settlement profile caused by mining subsidence, on the basis of a Winklersoil model, analytical equations for the moment-rotation response ofsoil during mining induced ground movements are developed. To define the full static moment-rotation response, an equation for the uplift-yield state is constructed and integrated with equations for the uplift- and yield-only conditions. The constructed model's findings reveal that the inverse of the factor of safety (x) has a considerable influence on the moment-rotation curve. The maximal moment-rotation response of the footing is defined by X = 0:6. Despite the use of Winkler model, the computed moment-rotation response results derived from the literature were analyzed through the ELM-SVM hybrid of Extreme Learning Machine (ELM) and Support Vector Machine (SVM). Also, Monte Carlo simulations are used to apply continuous random parameters to assess the transmission of ground motions to structures. Following the findings of RMSE and R2, the results show that the choice of probabilistic laws of input parameters has a substantial impact on the outcome of analysis performed.

• Journal of the Korea Concrete Institute
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• v.16 no.4 s.82
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• pp.477-484
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• 2004

As a part of durability improvement of concrete-structure, penetrating water repellency of liquid type is applied to concrete surface. Besides, a related standard is made recently, but the standard has been prescribe for initial settlement state of penetrating water repellency of liquid type, to the exclusion of performance variation depending time and outdoor environment factor. For measurement of performance variation, we measured the weight of outdoor exposure specimen every regular intervals and check a measured value against a measured value of different condition specimen. Moreover, after the application of penetrating water repellent, measured a adhesive strength in tension between cement-polymer modified waterproof coatings and surface of specimen. The applied penetrating water repellent is a emulsified silicon type with a deep penetration depth. In view of the results so far achieved, the more a Quantity of application and active solid content does get, the deeper penetrating water repellency of emulsion type Penetrate get longer and supplied moisture increase in quantity, a penetrating water repellency of liquid type penetrates more deep, but a quantity of water absorption increase gradually. Perhaps this result is caused by a reduction of active solid content on concrete surface, because active ingredient is moved into the concrete by dissolution.