• Title/Summary/Keyword: Surface circulation

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Surface Modification of Liposomes Using Comblike Copolymer for Enhancing Stability in Blood Circulation (혈류 내 안정성 향상을 위한 빗 모양 고분자로 개질된 리포솜)

  • Sin, Byeong-Cheol;Song, Chung-Gil;Hwang, Tae-Won;Seong, Ha-Su;Park, Eun-Seok
    • Journal of the Korean Chemical Society
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    • v.50 no.3
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    • pp.216-223
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    • 2006
  • To increase the stability of liposomes in blood circulation, surface modification of liposomes by incorporating a lipid-polymer derivative in the lipid bilayer or conjugating a hydrophilic polymer to the liposomal surface has been developed. In this study, the comblike copolymer, poly(HEMA-co-HPOEM), having multiple polyethyleneoxide side chains was prepared by free radical polymerization of hydroxyethylmethacrylate (HEMA) and hydroxypolyoxyethylenemethacrylate (HPOEM) as vinyl monomers. Poly(HEMA-co-HPOEM) was conjugated to the liposomal surface and the characteristics of the modified liposomes in serum were investigated. Conjugation of poly(HEMA-co-HPOEM) to liposomes increased the particle size of the liposomes by 30 nm and decreased the absolute value of zeta potential of the liposomes by shielding the negative charge of liposomal surface. Loading efficiency of model drug, doxorubicin, in liposomes was about 90% and the efficiency was not affected by conjugation of poly(HEMA-co-HPOEM) to liposomes. The particle size of poly(HEMA-co-HPOEM)-conjugated liposomes in serum did not changed and the protein adsorption was lower than that of control liposomes or liposomes containing polyethyleneoxide-lipid derivative (PEG-liposomes). These results suggest that poly(HEMA-co-HPOEM) is efficient for the stabilization of liposomes in blood circulation.

Seasonal Predictability of Typhoon Activity Using an Atmospheric General Circulation Model and Observed Sea Surface Temperature Data (대기 대순환 모헝과 해수면 온도 관측 자료를 이용한 태풍 활동의 계절 예측 가능성)

  • Han, Ji-Young;Baik, Jong-Jin
    • Journal of the Korean earth science society
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    • v.27 no.6
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    • pp.653-658
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    • 2006
  • The seasonal predictability of typhoon activity over the western North Pacific is investigated using an atmospheric general circulation model GCPS. A ten-member ensemble with different initial conditions is integrated for five months using observed sea surface temperature data for each year from 1979 to 2003. It is shown that the monthly variation of occurrence frequency of simulated tropical storms and the distribution of tropical storm genesis location are similar to those of observed tropical storms, but the model is unable to reliably predict the interannual variation of the occurrence frequency of tropical storms. This is largely because the observed relationship between tropical storm occurrence frequency and ENSO is different from the simulated one. Unlike the observation, in which the tropical storm occurrence frequency has no relation to ENSO, the model has a tendency to generate more (less) tropical storms than normal during El Nino (La Nina). On the other hand, the interannual variation of the mean longitude of tropical storms that shows a close connection with ENSO in both observations and simulations is simulated similar to the observation.

Depositional Processes of Fine-Grained Sediments and Foraminiferal Imprint of Estuarine Circulation by Summer Floods in Yoja Bay, Southern Coast of Korea

  • Lee, Yeon-Gyu;Jung, Kyu-Kui;Woo, Han-Jun;Chu, Yong-Shik
    • Journal of the korean society of oceanography
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    • v.35 no.2
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    • pp.109-123
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    • 2000
  • Depositional processes of fine-grained sediments were investigated on the basis of sediment transport vector analysis and identification of benthic foraminiferal assemblages in Yoja Bay, southern coast of Korea. The bay is a semi-enclosed embayment where extensive mud flats occur with a width up to about 4 km. Most surface sediments are poorly sorted (sorting values: 1.9-3.0 ${\phi}$) mud and silt (mean grain size: 6.0-8.7 ${\phi}$), except for the tidal inlets with basement rocks locally exposed. Grain-size distribution shows a fining tendency toward the basin center near the Yoja Island, implying a possible existence of turbidity maximum and relatively rapid settling of fine-grained sediments. The agglutinated foraminiferal taxa are dominant in the inner bay and decrease in abundance toward the mouth of the bay. Species diversities are higher in the outer bay, due to mixing of the offshore faunas with those of the bay. Four groups of benthic foraminiferal assemblages, identified by cluster analysis, represent the bay. Biofacies I and ll with relatively lower diversities are dominated by Ammobaculites exiguus and Ammonia beccarii, suggestive of influx of fresh water. In contrast, biofacies III and IV with relatively higher diversities include increased amounts of calcareous genus Elphidium and Quinquelocuzina, accounting for strong influence of sea water from the offshore. The fluvial discharge in summer floods appears to develop a bay-wide, clockwise lateral circulation in Yoja Bay, a typical of well-mixed estuaries. Accordingly, the foraminiferal assemblages of the surface sediments well show a sign of this circulation. The dominant inflow of the offshore water into the western part of the bay has resulted in more extensive muddy tidal flats compared to the eastern narrower counterpart.

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Predictability of Sea Surface Temperature in the Northwestern Pacific simulated by an Ocean Mid-range Prediction System (OMIDAS): Seasonal Difference (북서태평양 중기해양예측모형(OMIDAS) 해면수온 예측성능: 계절적인 차이)

  • Jung, Heeseok;Kim, Yong Sun;Shin, Ho-Jeong;Jang, Chan Joo
    • Ocean and Polar Research
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    • v.43 no.2
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    • pp.53-63
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    • 2021
  • Changes in a marine environment have a broad socioeconomic implication on fisheries and their relevant industries so that there has been a growing demand for the medium-range (months to years) prediction of the marine environment Using a medium-range ocean prediction model (Ocean Mid-range prediction System, OMIDAS) for the northwest Pacific, this study attempted to assess seasonal difference in the mid-range predictability of the sea surface temperature (SST), focusing on the Korea seas characterized as a complex marine system. A three-month re-forecast experiment was conducted for each of the four seasons in 2016 starting from January, forced with Climate Forecast System version 2 (CFSv2) forecast data. The assessment using relative root-mean-square-error was taken for the last month SST of each experiment. Compared to the CFSv2, the OMIDAS revealed a better prediction skill for the Korea seas SST, particularly in the Yellow sea mainly due to a more realistic representation of the topography and current systems. Seasonally, the OMIDAS showed better predictability in the warm seasons (spring and summer) than in the cold seasons (fall and winter), suggesting seasonal dependency in predictability of the Korea seas. In addition, the mid-range predictability for the Korea seas significantly varies depending on regions: the predictability was higher in the East Sea than in the Yellow Sea. The improvement in the seasonal predictability for the Korea seas by OMIDAS highlights the importance of a regional ocean modeling system for a medium-range marine prediction.

Analysis of Water Circulation Characteristics for Hydraulic and Water Temperature Investigation in Paldang Reservoir (팔당호의 수리 및 수온 조사를 통한 물순환특성 분석)

  • Choi, Hwang Jeong;Cho, Yong-Chul;Yu, Soonju;Song, Yong Sik;Ryu, Ingu
    • Ecology and Resilient Infrastructure
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    • v.6 no.1
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    • pp.12-22
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    • 2019
  • This study investigated the spatial and temporal water circulation characteristics of Paldang Reservoir by continuous hydraulic and water temperature survey. Due to differences in water temperature and discharge pattern of Ipo Weir and Cheongpyeong Dam, the flow and temperature fluctuations were different in sections of Namhan River and Bukhan River in Paldang Reservoir. At the stratification period, the water temperature of the discharge of Ipo Weir was higher than that of the Cheongpyeong Dam. Therefore, in the surface layer of the downstream of Bukhan River, relatively high temperature water is located and back water phenomenon occurred, and convergence zone is formed. In the downstream section of Namhan River, low-temperature water was distributed in the middle and lower layers, and the upstream flow appeared to be difficult to mix with the surface layer.

Numerical Simulation Experiment on the Wind Ventilation Lane of the Local Circulation Winds in Daegu (대구지역의 국지적 대기순환풍의 환기경로에 관한 수치모의 실험)

  • Gu, Hyeon Suk;Kim, Hae Dong;Gang, Seong Dae
    • Journal of Environmental Science International
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    • v.13 no.4
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    • pp.367-376
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    • 2004
  • In urban area, thermal pollution associated with heat island phenomena is generally regarded to make urban life uncomfortable. To overcome this urban thermal pollution problem, urban planning with consideration of urban climate, represented by the concept of urban ventilation lane, is widely practiced in many countries. In this study, the prevailing wind ventilation lane of a local winds in Daegu during the warm climate season was investigated by using surface wind data and RAMS(Reasonal Atmospheric Model System) simulation. The domain of interest is the vicinity of Daegu metropolitan city(about 900 $km^{2})$ and its horizontal scale is about 30km. The simulations were conducted under the synoptic condition of late spring with the weak gradient wind and mostly clear sky. From the numerical simulations, the following two major conclusions were obtained: (1)The major wind passages of the local circulation wind generated by radiative cooling over the mountains(Mt. Palgong and Mt. Ap) are found. The winds blow down along the valley axis over the eastern part of the Daegu area as a gravity flow during nighttime. (2)After that time, the winds blow toward the western part of Daegu through the city center. As the result, the higher temperature region appears over the western part of Daegu metropolitan area.

A study on the atmospheric response to a SST anomaly over the Equatorial Eastern Pacific Ocean with the horizontally fine resolution AGCM (수평조밀격자 GCM을 이용한 적도 태평양상의 SST anomaly에 대한 대기 반응 연구)

  • Moon, Sung-Eui;Ahn, Joong-Bae;Kim, Yoo-Keun
    • Journal of Environmental Science International
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    • v.4 no.5
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    • pp.403-411
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    • 1995
  • The atmospheric responses to a Sea Surface Temperature Anomaly(SSTA) over the equatorial eastern Pacific Ocean have been investigated using the horizontally fine resolution model based on OSU 2-layer Atmospheric General Circulation Model(AGCM). The SSTAS daring the peak phase of 1982-83 El Nino have been applied to the model as the boundary conditions of the experiment. The model simulates the eastward movement of the rising branch of the Walker circulation. That is, the major features associated with the El Nino such as the increase of the precipitation rate over the center of the Pacific and decrease over the Indonesia, and the 500hPa geopotential height anomaly in the middle latitude are properly describes in the fine resolution model experiment. The model results indicate that this horizontally fine resolution UM can successfully simulate the ENSO anomalies and be more effectivelly used for the study of the climate and the climate changes.

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Numerical Simulation of Ozone using UAM-V on Summer Episode in the Costal Urban Area, Busan (UAM-V를 이용한 부산지역 고농도 오존사례 수치모의)

  • 김유근;오인보;황미경
    • Journal of Korean Society for Atmospheric Environment
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    • v.19 no.1
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    • pp.1-11
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    • 2003
  • Temporal and horizontal distributions of surface ozone concentrations covering the Busan metropolitan area were simulated by UAM -V (The Variable grid Urban Airshed Model) that was run with meteorological inputs taken from MM5 for ozone episode day (18 July 1999). UAM-V underestimated the daily maximum ozone con-centration about 14 ppb on average at all monitoring sites within Busan area comparing with observed value. but the correlation between observed and simulated values showed quite significant (R = 0.896, p< 0.01 on average). Higher concentrations of ozone occurred near the city center and industrial areas (western side of city) with high levels of anthropogenic source in the morning, and transport of ozone and its precursors by sea breeze developed in the afternoon contributed to elevated ozone levels in downwind rural areas. Particalarly in slightly downwind area of city center, the highest daily maximum ozone concentration ($\geq$120 ppb) was simulated by UAM-V at 1400 LST. Consequently, local environments including emission distributions and land -sea breeze circulation influenced ozone distributions in the Busan metropolitan area.

The Internal Finishing Characteristics of Non-ferromagnetic Pipe Polished by Magnetic Abrasive Machining(III) (자기연마법에 의한 비자성 파이브 내면의 연마특성(III))

  • Park, W. K.;Rho, T. W.;Seo, Y. I.;Choi, H.;lee, J. C.;Cheong, S. H.
    • Proceedings of the Korean Society of Precision Engineering Conference
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    • 1997.10a
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    • pp.915-918
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    • 1997
  • An internal finishing process by the application of magnetic abrasive machining has been developed as a new technology to obtain a fine inner surface of pipe. In this paper, an abrasive circulation system was designed and manufactured. As a result, it was found that a fine inner surface abrasive of pipe was available by the use of this machining methods. The basic machining characteristics of pin-type magnetic tools were analyzed experimentally. In addition, the experimental results show that we can realize that pin-type magnetic tools have more machining efficiency than iron particles as magnetic tools.

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동전기-생물학적복원기술과 계면활성제를 이용한 phenanthrene 오염토양의 정화

  • 김상준;박지연;이유진;양지원
    • Proceedings of the Korean Society of Soil and Groundwater Environment Conference
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    • 2004.09a
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    • pp.186-190
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    • 2004
  • The electrokinetic bioremediation employing electrolyte circulation method was carried out for the cleanup of phenanthrene-contaminated kaolinite, and microorganism used in the biodegradation of phenanthrene was Sphingomonas sp. 3Y. The electrolyte circulation method supplied ionic nutrientsand the microorganism into soil, and inhibited the significant pH change of soil by increasing the soil buffering capacity by providing phosphate buffer compounds. When the remediation process was conducted without surfactant, the removal efficiency of phenanthrene, at the initial concentration of 200 ppm, was 69% for only 7 days. Higher microbial population and lower phenanthrene concentration were observed in the anode and middle regions of soil specimen than in the cathode region. The higher density of microorganism was because the microbial movement was in the direction of the anode part due to the negative surface charge. When Triton X-100 and APG of 20 g/1 were used to improve the bioavailability of phenanthrene strongly adsorbed onto soil surface, about 90 and 39% of phenanthrene removal were obtained. Consequently, it was confirmed that the microorganism preferred APC to phenanthrene as carbon source and so the removal efficiency with APG decreased less than that without APG.

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