• Pediatric Gastroenterology, Hepatology & Nutrition
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• v.24 no.4
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• pp.377-383
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• 2021

Purpose: We investigated the association of effector memory (EM) CD8⁺ T cell and CD4⁺ T cell immunity with metabolic syndrome (MS). Methods: Surface and intracellular staining of peripheral blood mononuclear cells was performed. Anti-interleukin-7 receptor-alpha (IL-7Rα) and CX3CR1 antibodies were used to stain the subsets of EM CD8⁺ T cells, while anti-interferon-gamma (IFN-γ), interleukin-17 (IL-17), and forkhead box P3 (FOXP3) antibodies were used for CD4⁺ T cell subsets. Results: Of the 47 obese children, 11 were female. Children with MS had significantly higher levels of serum insulin (34.8±13.8 vs. 16.4±6.3 µU/mL, p<0.001) and homeostasis model assessment of insulin resistance (8.9±4.1 vs. 3.9±1.5, p<0.001) than children without MS. Children with MS revealed significantly higher frequencies of IL-7Rα^low CD8⁺ T cells (60.1±19.1% vs. 48.4±11.5%, p=0.047) and IL-7Rα^lowCX3CR1⁺ CD8⁺ T cells (53.8±20.1% vs. 41.5±11.9%, p=0.036) than children without MS. As the serum triglyceride levels increased, the frequency of IL-7Rα^lowCX3CR1⁺ and IL-7Rα^highCX3CR1^- CD8⁺ T cells increased and decreased, respectively (r=0.335, p=0.014 and r=-0.350, p=0.010, respectively), in 47 children. However, no CD4⁺ T cell subset parameters were significantly different between children with and without MS. Conclusion: In obese children with MS, the changes in immunity due to changes in EM CD8⁺ T cells might be related to the morbidity of obesity.

• Clean Technology
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• v.26 no.4
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• pp.263-269
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• 2020

Zeolite was synthesized hydrothermally using the water-treatment sludge, and the effects of various synthesis parameters like reaction temperature, reaction time, and Na2O/SiO2 molar ratio on the crystallization of zeolite were investigated. Crystal structure, physical property, and thermal stability of zeolite crystals were characterized by X-ray powder diffraction, FTIR spectroscopy, BET nitrogen adsorption, and TGA measurements. The removal efficiencies of nitrogen in ammonia, heavy metal ions, and TOC were calculated to evaluate zeolite's adsorption capacity. The primary chemical composition of water-treatment sludge was 28.79% Al2O3 and 27.06% SiO2. The zeolites were synthesized by merely employing the water-treatment sludge as silica and alumina sources without additional chemicals. Zeolite crystals synthesized through the water-treatment sludge were confirmed as an A-type zeolite structure. Zeolite A had the highest crystallinity obtained from a gel with the molar composition 2.1Na2O-Al2O3-1.6SiO2-65H2O after 5 h at a temperature of 90 ℃. The specific surface area of zeolite obtained was 55 ㎡ g-1, which was higher than commercial zeolite A. The removal efficiency of nitrogen in ammonia was 68% after 3 h of reaction time, while the removal efficiencies of Pb2+ and Cd2+ ions were 99.1% and 99.3%, respectively. These results indicate active ion exchange between Pb2+ or Cd2+ ion and Na+ ion in the zeolite framework. The adsorption experiments on the different zeolite addition conditions were performed for 3 h with 300 ppm humic acid. Based on the results, TOC's highest efficiency was 83% when 5 g of zeolite was added.

• Ecology and Resilient Infrastructure
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• v.8 no.1
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• pp.44-53
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• 2021

The flood prevention capacity of drainage facilities in urban areas has weakened because of the increase in impervious surface areas downtown owing to rapid urbanization as well as localized heavy rains caused by climate change. Detention can be installed in trunk sewers and linked to existing drainage facilities for the efficient drainage of runoff in various urban areas with increasing stormwater discharge and changing runoff patterns. In this study, the concept of detention in trunk sewers, which are storage facilities linked to existing sewer pipes, was applied. By selecting a virtual watershed with a different watershed shape, the relationship between the characteristic factors of detention in the trunk sewer and the design parameters was analyzed. The effect of reducing stormwater runoff according to the installation location and capacity of the reservoir was examined. The relationship between the installation location and the capacity of the detention trunk sewer in the Dowon district of the city of Yeosu, South Korea was verified. The effects of the existing water runoff reduction facility and the detention trunk sewer were also compared and analyzed. As a result of analyzing the effects of reducing internal inundation, it was found that the inundation area decreased by approximately 66.5% depending on the installation location of the detention trunk sewer. The detention trunk sewer proposed in this paper could effectively reduce internal inundation in urban areas.

• Journal of the Korea Academia-Industrial cooperation Society
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• v.22 no.3
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• pp.13-19
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• 2021

This study examined the effects of stacking faults on the thermoelectric properties for n-type SiC semiconductors. Porous SiC semiconductors with 30~42 % porosity were fabricated by the heat treatment of pressed ��-SiC powder compacts at 1600~2100 ℃ for 20~120 min in an N2 atmosphere. XRD was performed to examine the stacking faults, lattice strain, and precise lattice parameters of the specimens. The porosity and surface area were analyzed, and SEM, TEM, and HRTEM were carried out to examine the microstructure. The electrical conductivity and the Seebeck coefficient were measured at 550~900 ℃ in an Ar atmosphere. The electrical conductivity increased with increasing heat treatment temperature and time, which might be due to an increase in carrier concentration and improvement in grain-to-grain connectivity. The Seebeck coefficients were negative due to nitrogen behaving as a donor, and their absolute values also increased with increasing heat treatment temperature and time. This might be due to a decrease in stacking fault density, i.e., a decrease in stacking fault density accompanied by grain growth and crystallite growth must have increased the phonon mean free path, enhancing the phonon-drag effect, leading to a larger Seebeck coefficient.

• Journal of the Korean Recycled Construction Resources Institute
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• v.8 no.4
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• pp.528-536
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• 2020

In this study, high strength mortar and normal strength mortar using waste glass sand were evaluated. The main parameters studied were mechanical properties, alkali-silica reaction(ASR) and residual mechanical properties after ASR. As a result of this experiment, it was found that the increase in strength of the mortar has a limitation in improving the slip of the waste glass sand(GS), and rather, it causes a larger ASR. However, the possibility of improving the slip of GS was confirmed by the temporary increase of initial residal compressive and flexural strength of the mortar containing GS after the ASR. Therefore, to improve the slip of GS, the additional research is required, such as modification of the surface of GS and the incorporation of a binder which can increase the strength and makes matrix compact.

• Journal of the Korea institute for structural maintenance and inspection
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• v.24 no.5
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• pp.9-16
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• 2020

A CFRP sheet has been applied as a structural reinforcement in the field, and various studies are conducted to evaluate the effect of CFRP sheets on reinforced concrete. Although many experiments were performed from previous studies, there are still limitations to analyze structural behaviors with various parameters in experiments directly. This study shows the FEA on structural behaviors of RC beams reinforced with CFRP sheets using ABAQUS software. To simulate debonding failure of CFRP sheets which is a major failure mode of RC beam with CFRP sheets, a cohesive element was applied between the bottom surface of RC beam and CFRP sheets. Both quasi-static method and 2-D symmetric FE model technique were performed to solve nonlinear problems. Results obtained from the FE models show good agreements with experimental results. It was found that reinforcement level of CFRP sheets is closely related to structural behavior of reinforced concrete including maximum strength, initial stiffness and deflection at failure. Also, as over-reinforcement of CFRP sheets could give rise to the brittle failure of RCstructure using CFRP sheets, an appropriate measure should be required when installing CFRP sheets in the structure.

• Korean Journal of Optics and Photonics
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• v.33 no.5
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• pp.218-229
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• 2022

We have investigated reliable inspection methods for finding the defects generated during the manufacturing process of lightweight, large-aperture satellite telescope mirrors using silicon carbide, and we have measured the basic physical properties of the mirrors. We applied the advanced ceramic material (ACM) method, a combined method using liquid-silicon penetration sintering and chemical vapor deposition for the carbon molded body, to manufacture four SiC mirrors of different sizes and shapes. We have provided the defect standards for the reflectors systematically by classifying the defects according to the size and shape of the mirrors, and have suggested effective nondestructive methods for mirror surface inspection and internal defect detection. In addition, we have analyzed the measurements of 14 physical parameters (including density, modulus of elasticity, specific heat, and heat-transfer coefficient) that are required to design the mirrors and to predict the mechanical and thermal stability of the final products. In particular, we have studied the detailed measurement methods and results for the elastic modulus, thermal expansion coefficient, and flexural strength to improve the reliability of mechanical property tests.

• Journal of Korea Water Resources Association
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• v.55 no.9
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• pp.679-686
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• 2022

As the occurrences of flash floods have increased due to climate change, faster and more accurate precipitation observation using X-band radar has become important. Therefore, the Ministry of Environment installed two dual-pol X-band radars at Samcheok and Uljin. The radar data used in this study were obtained from two different elevation angles and composed to reduce the shielding effect. To obtain quantitative rainfall, quality control (QC), K_DP retrieval, and Hybrid Surface Rainfall (HSR) methods were sequentially applied. To improve the accuracy of the quantitative precipitation estimation (QPE) of the X-band radar, we retrieved parameters for the relationship between rainfall rate and specific differential phase, which is commonly called the R-K_DP relationship; hence, an empirical approach was developed using multiple rain gauges for those two radars. The newly suggested relationship, R = 27.4K^0.81_DP, slightly increased the correlation coefficient by 1% more than the relationship suggested by the previous study. The root mean square error significantly decreased from 3.88 mm/hr to 3.68 mm/hr, and the bias of the estimated precipitation also decreased from -1.72 mm/hr to -0.92 mm/hr for overall cases, showing the improvement of the new method.

• Applied Chemistry for Engineering
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• v.34 no.1
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• pp.23-29
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• 2023

Microfluidic reactors have been made to achieve significant development for the generation of new functional materials to apply in a variety of fields. Over the last decade, microfluidic reactors have attracted attention as a user-friendly approach that is enabled to control physicochemical parameters such as size, shape, composition, and surface property. Here, we develop a centrifugal microfluidic reactor that can control the flow of fluid based on centrifugal force and generate multifunctional particles of various sizes and compositions. A centrifugal microfluidic reactor is fabricated by combining microneedles, micro- centrifuge tubes, and conical tubes, which are easily obtained in the laboratory. Depending on the experimental control param- eters, including centrifuge rotation speed, alginate concentration, calcium ion concentration, and distance from the needle to the calcium aqueous solution, this strategy not only enables the generation of size-controlled microparticles in a simple and reproducible manner but also achieves scalable production without the use of complicated skills or advanced equipment. Therefore, we believe that this simple strategy could serve as an on-demand platform for a wide range of industrial and academic applications, particularly for the development of advanced smart materials with new functionalities in biomedical engineering.

• Nuclear Engineering and Technology
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• v.26 no.3
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• pp.401-410
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• 1994

Validation study of two radionuclide migration models for single fracture developed in geologic medium the hydrodynamic dispersion diffusion model(HDDM) and the channeling dispersion diffusion model(CDDM), was studied by migration experiment of tracers through an artificial granite fracture on the labolatory scale. The tracers used were Uranine and Sodium lignosulfonate know as nonsorbing material. The flow rate ranged 0.4 to 1.5 cc/min. Related parameters for the models were estimated by optimization technique. Theoretical breakthrough curves with experimental data were compared. In the experiment, it was deduced that the surface sorption for both tracers did not play an important role while the diffusion of Uranine into the rock matrix turned out to be an important mass transfer mechanism. The parameter characterizing the rock matrix diffusion of each model agreed well The simulated result showed that the amount of flow rate could not tell the CDDM from the HDDM quantitatively. On the other hand, the variation of fracture length gave influence on the two models in a different degree. The dispersivity of breakthrough curve of the CDDM was more amplified than that of the CDDM when the fracture length was increased. A good agreement between the models and experimental data gave a confirmation that both models were very useful in predicting the migration system through a single fracture.