• Korean Journal of Remote Sensing
• /
• v.17 no.2
• /
• pp.121-129
• /
• 2001

A DEM(digital elevation model) is generated from a SPOT panchromatic stereo-pair using automated algorithms over a 8 km$\times$10 km region around Mokpo city. The aims are to continue the accuracy assessment over diverse conditions and to examine the applicability of a SPOT DEM for coastal disaster monitoring. The accuracy is assessed with respect to three reference data sets: 10 global positioning system records, 19 leveling data, and 1:50,000 topography map. The planimetric error is 10.6m r.m.s. and the elevation erroer ranges from 12.4m to 14.4m r.m.s.. The DEM accuracy of the flat Mokpo region is consistent with that over a mountainous area, which supports the robustness of the algorithms. It was found that coordinate transformation errors are significant at a few meters when using the data from leveling and topographic maps. The error budget is greater than the requirements for coastal disaster monitoring. Exploiting that a sub-scene is used, the affine transformation improves the accuracy by 50% during the camera modeling.

• Genomics & Informatics
• /
• v.16 no.4
• /
• pp.38.1-38.3
• /
• 2018

Gene-gene interaction (GGI) analysis is known to play an important role in explaining missing heritability. Many previous studies have already proposed software to analyze GGI, but most methods focus on a binary phenotype in a case-control design. In this study, we developed "Hierarchical structural CoMponent analysis of Gene-Gene Interactions" (HisCoM-GGI) software for GGI analysis with a continuous phenotype. The HisCoM-GGI method considers hierarchical structural relationships between genes and single nucleotide polymorphisms (SNPs), enabling both gene-level and SNP-level interaction analysis in a single model. Furthermore, this software accepts various types of genomic data and supports data management and multithreading to improve the efficiency of genome-wide association study data analysis. We expect that HisCoM-GGI software will provide advanced accessibility to researchers in genetic interaction studies and a more effective way to understand biological mechanisms of complex diseases.

• Genomics & Informatics
• /
• v.16 no.4
• /
• pp.39.1-39.3
• /
• 2018

The rapid increase in genetic dataset volume has demanded extensive adoption of biological knowledge to reduce the computational complexity, and the biological pathway is one well-known source of such knowledge. In this regard, we have introduced a novel statistical method that enables the pathway-based association study of large-scale genetic dataset-namely, PHARAOH. However, researcher-level application of the PHARAOH method has been limited by a lack of generally used file formats and the absence of various quality control options that are essential to practical analysis. In order to overcome these limitations, we introduce our integration of the PHARAOH method into our recently developed all-in-one workbench. The proposed new PHARAOH program not only supports various de facto standard genetic data formats but also provides many quality control measures and filters based on those measures. We expect that our updated PHARAOH provides advanced accessibility of the pathway-level analysis of large-scale genetic datasets to researchers.

• Journal of Preventive Medicine and Public Health
• /
• v.55 no.6
• /
• pp.499-505
• /
• 2022

Despite advances in medicine and preventive strategies, fewer than 1 in 5 people with hypertension have the problem under control. This could partly be due to gaps in fully elucidating the etiology of hypertension. Genetics and conventional lifestyle risk factors, such as the lack of exercise, unhealthy diet, excess salt intake, and alcohol consumption, do not fully explain the pathogenesis of hypertension. Thus, it is necessary to revisit other suggested risk factors that have not been paid due attention. One such factor is psychosocial stress. This paper explores the evidence for the association of psychosocial stressors with hypertension and shows that robust evidence supports the role of a chronic stressful environment at work or in marriage, low socioeconomic status, lack of social support, depression, anxiety, post-traumatic stress, childhood psychological trauma, and racial discrimination in the development or progression of hypertension. Furthermore, the potential pathophysiological mechanisms that link psychosocial stress to hypertension are explained to address the ambiguity in this area and set the stage for further research.

• International conference on construction engineering and project management
• /
• 2005.10a
• /
• pp.748-753
• /
• 2005

In a super-highrise residence project, a project manager needs to form the long-term risk management plan which covers the problems from the beginning of project to the time of demolition. The cause and responsibility for a risk are clarified and quantitatively evaluated through the life cycle of a project. Development of the system which supports a risk strategy effectively is needed as a project becomes complex. In this paper, through the life cycle of a specific super-highrise residence project, a risk phenomenon is specified from a viewpoint of each participant, and the mathematical model is formulated choosing the combination of the optimal strategy against a risk quantitatively within a fixed risk strategy budget.

• The Bulletin of The Korean Astronomical Society
• /
• v.45 no.1
• /
• pp.44.3-44.3
• /
• 2020

Sunspot substructure is an important subject to explain their stability and energy transport. Previous studies suggested two substructure models, monolithic and spaghetti model, but no clear evidence has been found supporting a particular model. To obtain the clue of the sunspot substructure the IRIS Mg II 2796Å slit-jaw images (SJI) were examined. The Mg II images formed in the chromosphere show bright patches inside umbrae which are regarded as an observational signature of upward propagating slow magnetohydrodynamic (MHD) waves. The slow MHD waves are expected to be generated by convective motion below the photosphere. By tracking the motion of the bright patches it is possible to estimate the locations of oscillation centers that correspond to the occurrence position of the convections. I investigated the spatial distribution of the oscillation center in a merging sunspot and found it is randomly distributed. It implies that the occurrence rate of the convective motion inside the sunspot is not much different from that of between the two sunspots, and supports the spaghetti model as the sunspot substructure.

• Journal of Nuclear Fuel Cycle and Waste Technology(JNFCWT)
• /
• v.21 no.3
• /
• pp.419-425
• /
• 2023

The Radiation and Decommissioning Laboratory of Central Research Institute (CRI) of Korea Hydro and Nuclear Power Co. (KHNP) performs research to technically support the effective management of radiological hazards to avoid risks to civilians, the workers, and the environment from the radiological risks. The laboratory mainly consists of three technical groups: decommissioning and SF technology group, radiation and chemistry group, and radwaste and environment group. The groups carry out various R&D such as decommissioning, spent fuel management, radiation protection, water chemistry management, and radioactive waste management. The laboratory also technically supports the calibration of radiometric instruments as a Korea Laboratory Accreditation Scheme (KOLAS), approval for decommissioning, guidance for radioactive waste management, state-of-the-art technology evaluations, and technology transfer.

• Human Ecology Research
• /
• v.61 no.4
• /
• pp.505-520
• /
• 2023

This study aims to assess the effectiveness of the Marriage Checkup (MC) in community settings. Participants (N=57) were recruited from family centers and participated in the MC, which consisted of assessment and feedback visits. Participants completed marital satisfaction assessments before and after the MC. Overall, the participants reported significant improvements in terms of marital satisfaction with a large effect size (d=0.87). Specifically, 77.2% of participants demonstrated an increase in marriage satisfaction. Among them, 30.6% experienced a clinically significant change (from a clinical state to a non-clinical state). The reliable change index (RCI) identified 15.8% of participants as showing reliable improvement. Changes in marital satisfaction were larger for men and participants who experienced more positive changes during the MC in terms of intimacy and understanding of how to improve their marital relationships. This study supports the MC as an evidence-based approach for improving relationship health in community settings.

• Molecules and Cells
• /
• v.46 no.11
• /
• pp.672-674
• /
• 2023

Schematic diagram of the interaction between the intestinal muscularis externa (MMΦ) macrophages and the enteric nervous system (ENS) neurons during different developmental periods. At the early postnatal stage, MMΦs play a critical role in ENS maturation and refinement through synaptic pruning and enteric neuron phagocytosis. In addition, during the adult stage, a specific MMΦ subset named neuron-associated (NA)-MMΦ, supports enteric neuronal survival and functions. Conversely, enteric neurons promote the phenotypic MMΦ changes by secreting transforming growth factor-β (TGFβ), transitioning them from a phagocytic phenotype in the early postnatal period to a neuroprotective and immune-surveillant phenotype in the young adult period. Disruptions in these interactions could lead to alterations in the enteric neuron numbers, ultimately resulting in reduced gut motility.

• Asian Journal for Public Opinion Research
• /
• v.12 no.3
• /
• pp.184-213
• /
• 2024

This research investigates the intricate dynamics governing loyalty and recommendation behaviors. The primary objective is to discern the impact of community development on user loyalty and its subsequent influence on product recommendations, using the Indonesian online brand community of the software Micromine as a case study. The technology acceptance model, which argues that adoption is done because of perceived ease, and cognitive dissonance theory, which describes how individuals adjust to reduce discomfort, provide the framework for this study. Utilizing a quantitative methodology, all 300 members of the online Micromine Indonesia community population were surveyed. The findings reveal that community members establish emotional connections through active participation in community forums. Satisfaction with the software's solutions in mining endeavors is prevalent among Micromine community members. Regression analysis showed that a positive attitude about the brand community was positively correlated with both brand loyalty (R² = .83) and the likelihood of recommending the brand (R² = .78). This supports both theories, where brand community members adopt technology and reduce discomfort by supporting community activities.