• Journal of the Korean Society of Marine Environment & Safety
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• v.24 no.1
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• pp.1-9
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• 2018

All ships should ensure stability in accordance with IMO regulations. However, GM is only used to determine ship stability because it takes a lot of time to validate all regulations. This is a problem given that the safety of vessels cannot be guaranteed, potentially leading to accidents. There is a need for a more intuitive and comprehensive method of confirming the stability of ships. This study developed a stability index that expresses ship stability in one value. An index equation is defined based on the 6 stability criteria for ships prescribed by IMO and the result of calculating the ship stability of a model ship. A stability index has been derived for each loading condition by applying the index equation to the same ship. It can clearly be seen that this stability index appropriately explains the criteria. In other words, it is possible to assess ship stability with one value and confirm whether the ship stability satisfies IMO regulations. This index will help masters and officers more easily and accurately check ship stability.

• Asian Pacific Journal of Cancer Prevention
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• v.15 no.1
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• pp.167-174
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• 2014

Tumor angiogenesis, growth and metastasis are three closely related processes. We therefore investigated the effects of barbigerone on all three in the B16F10 tumor model established in both zebrafish and mouse models, and explored underlying molecular mechanisms. In vitro, barbigerone inhibited B16F10 cell proliferation, survival, migration and invasion and suppressed human umbilical vascular endothelial cell migration, invasion and tube formation in concentration-dependent manners. In the transgenic zebrafish model, treatment with $10{\mu}M$ barbigerone remarkably inhibited angiogenesis and tumor-associated angiogenesis by reducing blood vessel development more than 90%. In vivo, barbigerone significantly suppressed angiogenesis as measured by H and E staining of matrigel plugs and CD31 staining of B16F10 melanoma tumors in C57BL/6 mice. Furthermore, it exhibited highly potent activity at inhibiting tumor growth and metastasis to the lung of B16F10 melanoma cells injected into C57BL/6 mice. Western blotting revealed that barbigerone inhibited phosphorylation of AKT, FAK and MAPK family members, including ERK, JNK, and p38 MAPKs, in B16F10 cells mainly through the MEK3/6/p38 MAPK signaling pathway. These findings suggested for the first time that barbigerone could inhibit tumor-angiogenesis, tumor growth and lung metastasis via downregulation of the MEK3/6/p38 MAPK signaling pathway. The findings support further investigation of barbigerone as a potential anti-cancer drug.

• Journal of Radiation Protection and Research
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• v.11 no.1
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• pp.70-76
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• 1986

In order to establish the national standards of neutron measurements, a manganese sulphate ($MnSO_4$) bath system was developed under the IAEA technical support. This bath system was made up of a spherical s.s. 316 L bath, of 3.5 mm thick and of 125 cm internal diagmeter, filled with a manganese sulphate solution, a solution circulating system, and a $^5Mn\;{\gamma}-ray$ monitoring system. The solution pumped from the bath was introduced into a Marinelli beaker-type monitor vessel which was equipped with two seperate detectors, $3.8cm{\phi}{\times}3.8cm$ NaI(T1) crystals. The performance of the system were tested using the neutron sources, $^{241}Am-Be\;and\;^{252}Cf$, mounted at the center of the bath. From the decay curve analysis of $^{56}Mn$ activity, neutron emission rate of $^{252}Cf$ by the comparative method was obtained to be $3.71{\times}10^7\;n/s\;per\;50{mu}g$ as of November 15, 1985.

• The Korea Journal of Herbology
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• v.21 no.4
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• pp.189-195
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• 2006

Objectives : It has been reported previously that the roots of Scutellaria baicalensis (known as Huang-Gum in Korean, henceforth referred to as S. baicalensis) could prevent neuronal cell death after global cerebral ischemia. In Genuine Korean medicine, S. baicalensis is known to relieve fever in upper body, and it was thus thought to be able to alleviate deteriorations in brain function. Methods : The protective effects of S. baicalensis against post-stroke memory retardation using 4-vessel occlusion model were examined in the present study. Results : S. baicalensis was shown to significantly alleviate the deficits in learning and memory by increasing the fraction of time spent in the quadrant in which the platform was initially placed ($34.9\;{\pm}\;3.2%$, p < 0.05) compared to that of the ischemia group ($28.0\;{\pm}\;2.5%$). The cytoprotective effect of S. baicalensis on CA1 hippocampal neurons was evaluated by measuring the neuronal cell density. Neuronal cell density in S. baicalensis extracts-treated ischemia group ($138.0\;{\pm}\;13.6\;cells/mm^2$) was significantly increased compared to saline-treated ischemia group ($22.1 \;{\pm}\;9.3\;cells/mm^2$, p < 0.05). In the study of OX-42 immunohistochemistry, S. baicalensis could decrease the micrgial activation in hippocampus after brain ischemia. Conclusion : These results may provide experimental support for the use of S. baicalensis in treating post-stroke memory impairment.

• Journal of the Korea Institute of Information and Communication Engineering
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• v.16 no.10
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• pp.2230-2236
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• 2012

Currently, the AC-to-DC power conversion system using diode rectifiers is mainly used in large vessels. Also, to reduce the total harmonic distortion(THD) of current and voltage, this system requires an additional phase-shifting transformer which can be powered multi-pulses. In this case, due to the installation of the transformer, the spatial or economic loss occurs. This paper presents a novel active rectification scheme using silicon controlled rectifier(SCR) or insulated gate bipolar transistor(IGBT) devices on behalf of the diode rectifiers which are currently operating in large vessels such as LNG Carrier(LNGC). The proposed system can use the low voltage source and reduce current and voltage harmonics generated by nonlinear loads connected to the power distribution bus and save economic costs by removing the phase-shifting transformers which are used in conventional system. Computer simulations are performed under the electric propulsion system which is operating in current large vessel. The results are shown in support of the improvement of THD included in the current and voltage wave forms of propulsion motor.

• Journal of Navigation and Port Research
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• v.38 no.2
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• pp.141-146
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• 2014

NIR(New Inspection Regime, hereinafter NIR) relating to the PSC(Port State Contorl, hereinafter PSC) has implemented in Asia-Pacific region under Tokyo-MOU from last January 2014. The most noticable difference between NIR and existing TF(Target Factor, hereinafter TF) is to evaluate company performance and to conduct PSC with flexible inspection interval on the basis of Ship Risk Profile; High Risk Ship, Standard Risk Ship and Low Risk Ship. Particularly deficiencies related to ISM Code, more than 5 deficiencies and detention record have a serious effect on the evaluation of Ship Risk Profile. Therefore ship and company are requested to ensure proper implementation of Safety Management System for the changed PSC tendency. Also RO(Recognized Organization, hereinafter RO) and Administration respectively should take suitable actions different to previous measures, such as implementation of cooperation and support system between vessel and company, changing subject and object for avoiding Mannerism in SMS audit, strengthening supervision on RO by Administration and establishment of private-public Partnership network.

• Journal of the Korean Ceramic Society
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• v.48 no.6
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• pp.520-524
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• 2011

The properties of manufactured SOFC unit cell using decalcomania method were investigated. The decalcomania method that used in ceramics, dish, vessel and etc. was the very simple process. The SOFC unit cell manufacturer using decalcomania method is very simple process. Especially, the decalcomania method was the most suitable manufacturing method for the segmented type SOFC. The cathode, prevent diffusion layer (PDL), anode functional layer (AFL) and electrolyte were manufactured using decalcomania method on porous anode support. The sintered electrolyte at 1450$^{\circ}C$ for 2 h using decalcomania method was very dense, and the thickness was about 10 ${\mu}m$. The cathode, the PDL and the AFL were manufactured using decalcomania method and was sintered at 1250$^{\circ}C$ for 2 h, and the sintered electrodes were the porous. As a result, with humidified hydrogen used as fuel, the cell with an 15 ${\mu}m$-thick AFL exhibited maximum power densities of 0.246, 0.364, 0.504W/$cm^2$ at 700, 750, 800$^{\circ}C$, respectively.

• The Journal of the Acoustical Society of Korea
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• v.37 no.1
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• pp.39-45
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• 2018

Compressive sensing allows recovering an original signal which has a small dimension of the signal compared to the dimension of the entire signal in a short period of time through a small number of observations. In this paper, we proposed a method for detecting tonal signal which caused by the machinery component of a vessel such as an engine, gearbox, and support elements. The tonal signal can be modeled as the sparse signal in the frequency domain when it compares to whole spectrum range. Thus, the target tonal signal can be estimated by S-OMP (Simultaneous-Orthogonal Matching Pursuit) which is one of the sparse signal recovery algorithms. In simulation section, we showed that S-OMP algorithm estimated more precise frequencies than the conventional FFT (Fast Fourier Transform) thresholding algorithm in low SNR (Signal to Noise Ratio) region.

• Journal of Navigation and Port Research
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• v.33 no.6
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• pp.423-428
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• 2009

Recently, the marine traffics have been increased along with enlargement of overseas commerce. Increasing the marine traffic may make higher the risk of marine accidents. Especially, the rate of accidents on costal area are more frequently. As if the marine safety information can be afforded to vessel and shore, the accident rate would be down. AIS AtoN is the navigational safety support device which is subject to functional requirements of IALA and technical standards of ITU. In this paper, we extend and implement the user-defined specification of AIS AtoN with message 21 for AIS basic information, messsage 6 for status report and message 12/14 for safety management.

• Laser Solutions
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• v.14 no.2
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• pp.8-12
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• 2011

As the aged population grows around the world, many medical instruments and devices have been developed recently. Among the devices, a drug delivery stent is a medical device which requires precision machining. Conventional drug delivery stent has problems of residual polymer and decoating because the drug is coated on the surface of stent with the polymer. If the drug is impregnated in micro hole array on the surface of the stent, the problem can be solved. Micro sized holes are generally fabricated by laser machining; however, the fabricated holes do not have an enough aspect ratio to contain the drug or a good surface finish to deliver it to blood vessel tissue. To overcome these problems, we propose a vibration-assisted machining mechanism with PZT (Piezoelectric Transducers) for the fabrication of micro sized holes. If the mechanism vibrates the eyepiece of the laser machining head, the laser spot on the workpiece will vibrate vertically because objective lens in the eyepiece shakes by the mechanism's vibration. According to the former researches, the vibrating frequency over 20kHz and amplitude over 500nm are preferable. The vibration mechanism has cylindrical guide, hollowed PZT and supports. In the cylinder, the eyepiece is mounted. The cylindrical guide has upper and low plates and side wall. The shape of plates and side wall are designed to have high resonating frequency and large amplitude of motion. The PZT also is selected to have high actuating force and high speed of motion. The support has symmetrical and rigid characteristics.