• The KIPS Transactions:PartC
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• v.16C no.2
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• pp.165-182
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• 2009

Mobile IPv6 spends considerable bandwidth considering that its signal volume is proportional to the mobile and also it should be strengthened to support the binding signal volume, the traffic, and effective mobility. So, the study in NEMO(Network Mobility), an extended version of Mobile IPv6, has been conducted. NEMO provides its mobility by putting several mobiles and more than one portable router into one unit called as mobile network. Because nodes access Internet via the portable router at this time, it receives transparency without any additional work and that much reduces binding signal while solving binding storm. By supporting mobility, NEMO is able to have various mobile structures which realize several networks hierarchically and it is necessary to improve its safety and security by authenticating among the upper networks or the lower ones while moving. Also, it is extremely required to begin a study in the device to improve efficiency accompanied with mobility, which is executed by the fast hand-off as well as the safe authentication. For those reasons, this paper not only classifies various NEMO mobile scenarios into 7 ways, but also provides AAA authentication of each scenario, the authentication through the safety authentication and fast handoff authentication using F+HMIPv6 and the way to reduce both signaling volume and packet delays efficiently during the handoff.

• Journal of the Society of Disaster Information
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• v.15 no.4
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• pp.524-530
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• 2019

Purpose: In this paper, we construct a detailed three-dimensional interface element using a three-dimensional analysis program, and evaluate the composite behavior stability of the connector by applying physical properties such as the characteristics of general members and those of reinforced members Method: The analytical model uses solid elements, including non-linear material behavior, to complete the modeling of beam structures, circular flanges, bolting systems, etc. to the same dimensions as the design drawing, with each member assembled into one composite behavior linkage. In order to more effectively control the uniformity and mesh generation of other element type contact surfaces, the partitioning was performed. Modeled with 50 carbon steel materials. Results: It shows the displacement, deformation, and stress state of each load stage by the contact adjoining part, load loading part, fixed end part, and vulnerable anticipated part by member, and after displacement, deformation, The effect of the stress distribution was verified and the validity of the design was verified. Conclusion: Therefore, if the design support of the micro pile is determined based on this result, it is possible to identify the Vulnerable Parts of the composite behavior connector and the degree of reinforcement.

• Journal of Intelligence and Information Systems
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• v.14 no.1
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• pp.1-17
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• 2008

Data mining is defined as the process of discovering meaningful and useful pattern in large volumes of data. In particular, finding associations rules between items in a database of customer transactions has become an important thing. Some data structures and algorithms had been proposed for storing meaningful information compressed from an original database to find frequent itemsets since Apriori algorithm. Though existing method find all association rules, we must have a lot of process to analyze association rules because there are too many rules. In this paper, we propose a new data structure, called a Frequent Pattern Network (FPN), which represents items as vertices and 2-itemsets as edges of the network. In order to utilize FPN, We constitute FPN using item's frequency. And then we use a clustering method to group the vertices on the network into clusters so that the intracluster similarity is maximized and the intercluster similarity is minimized. We generate association rules based on clusters. Our experiments showed accuracy of clustering items on the network using confidence, correlation and edge weight similarity methods. And We generated association rules using clusters and compare traditional and our method. From the results, the confidence similarity had a strong influence than others on the frequent pattern network. And FPN had a flexibility to minimum support value.

• Archives of Plastic Surgery
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• v.37 no.6
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• pp.721-725
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• 2010

Purpose: The survival of composite graft is dependent on three steps, (1) plasmatic imbibitions, (2) inosculation, and (3) neovascularization. Among the many trials to increase the survival rate of composite graft, prostaglandin E1 (PGE1) has beneficial effects on the microcirculatory level with vasodilating, antithrombotic, anti-inflammatory and neoangiogenic properties. Lipo-PGE1 which is lipid microspheres containing PGE1 had developed to compensate the systemic and local side effects of PGE1. This study was proposed to determine whether Lipo-PGE1 administration enhanced the survival of composite graft through neovascularization quantitatively in a rabbit ear model. Methods: Fourteen New Zealand White Rabbits each weighing 3~4 kg were divided in two groups: (1) intravenous Lipo-PGE1 injection group and (2) control group. A $2{\times}1\;cm$ sized, full-thickness rectangular composite graft was harvested in each auricle. Then, the graft was reaaproximated in situ using a 5-0 nylon suture. For the experimental group, $3{\mu}g$/kg/day of Lipo-PGE1 ($5{\mu}g$/mL) was administered intravenously through the marginal vein of the ear for 14 days. The control group was received no pharmacologic treatment. On the 14th postoperative day, composite graft of the ear was harvested and immunochemistry staining used Monoclonal mouse anti-CD 31 antibody was performed. Neoangiogenesis was quantified by counting the vessels that showed luminal structures surrounded by the brown color-stained epithelium and counted from 10 random high-power fields (400x) by independent blinded observer. Statistical analysis (Wilcoxon Signed Ranks test for nonparametric data) was performed using SPSS v12.0, with values of p<0.05 considered significant. Results: The mean number of the microvessels was $15.48{\pm}8.65$ in the experimental group and $9.82{\pm}7.25$ in the control group (p=0.028). Conclusion: The use of Lipo-PGE1 facilitated the neoangiogenesis, resulted in the improvement of the survival rate of graft. On the basis of this results, we could support wider application of Lipo-PGE1 for more effective therapeutic angiogenesis and successful survival in various cases of composite graft in the human.

• Journal of the Korea Academia-Industrial cooperation Society
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• v.18 no.4
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• pp.154-162
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• 2017

The aim of study was to identify the reliability and validity of an evaluation tool developed on the basis of performance outcome in Women's Health Nursing simulation practicum. A total of 110 undergraduate nursing students were recruited from one college. Data collection of this study was conducted between August and December of 2014. The data were analyzed using factor analysis, multitrait/multi-item matrix analysis, Pearson's correlation coefficient, and Cronbach's alpha with SPSS win 20.0 program. An exploratory factor analysis demonstrated that the four-factor structures of 10 items explained 68.2% of the total variance. It was significantly correlated with the Critical Thinking Disposition scale(r=.42, p <.001). The Cronbach's alpha was 0.89,ranging from 0.61 to 0.92. The results of this study support the reliability and validity of this evaluation tool. It could be a useful tool in evaluating the performance outcome in simulation practicum for nursing students.

• Korean Journal of Remote Sensing
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• v.18 no.4
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• pp.209-220
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• 2002

We carried out studies on SAR image intensity and interferometric phase over oyster sea farms. Strong backscattering was observed in amplitude images, and that was considered as a radar signal double bouncing from horizontal bars. These sea farming structures are not visible in satellite optical images except IKONOS image, so that it demonstrates the value of radar remote sensing as an effective tool in support of sea farm detection. The intensity of the image is sensitive to system parameters including wavelength, polarization, and look direction, but does not correlate to tide height. We found that the strongest backscattering can be obtained by L-band HH-polarization with a look direction perpendicular to the horizontal bar. We also succeeded in generating 21 coherent JERS-1 SAR interferometric pairs over the oyster farms. The general trend of the fringe rate of the interferometric phases appeared to be governed by altitude of ambiguity. The general trend was modeled by an inverse function and removed to have a residual phase. The residual phase showed a linear relation with the tide height. The results demonstrate for the first time that SAR can possibly be used to estimate sea level. However, the r.m.s. error of a regression line is 11.7 cm, and that is so far too large to make reliable assessments of sea level in practical applications. Further studies is required to improve the accuracy specifically using multi-polarization SAR data.

• Journal of the Korea institute for structural maintenance and inspection
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• v.23 no.3
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• pp.1-8
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• 2019

Steel elevator pit was developed for the purpose of minimizing the excavation, simplifying the construction of the frame and economical efficiency by improving the problems that occurred in the existing reinforced concrete. It is common to apply conventional RC method through excavation to underground structures such as underground floor collector well and elevator pit. In recent years, the use of steel collector well and steel elevator pits to reduce construction costs by minimizing the materials of steel and concrete has been continuously increasing. The steel elevator pit is an underground structure and then the performance of the welding part and the structure system is important. Specimen with only steel plate and concrete without studs could support the load more than 3 times than the specimen with deck only. Therefore, even if there is no stud, the deck (steel plate) rib is formed and the effect of restraining the steel plate and the concrete during the bending action can be expected. However, since sudden fracture in the elevator pit may occur, stud bolt arrangement is necessary for the composite effect of steel plate and concrete. It is expected that the bending strength can be expected to increase by about 15% or more depending with and without stud bolts.

• Journal of Korean Tunnelling and Underground Space Association
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• v.21 no.3
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• pp.363-375
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• 2019

Since the double-deck tunnel is deeply constructed in the city, it is necessary to secure the installation space of air supply and exhaust, escape passage stairs, elevator, distribution facilities and connection tunnels in the vertical shaft for the double-deck tunnel. Also, in order to minimize the effect of construction on adjacent area, it is necessary to construct the concrete structures at high speed in vertical shaft after tunnel excavation. Therefore, the slabs and the stairs in vertical shaft are needed to be constructed using precast concrete, and the rapid construction techniques of bracket for supporting the inner precast structure are needed. The bracket installation methods include cast-in-place concrete, precast concrete and steel. In this study, the improvement of the steel brackets with good economical efficiency and good workability was carried out in consideration of the improvement of the construction speed. We have developed a new bracket that is optimized through bracket shape improvement, anchor bolt position adjustment and quantity optimization. As a result of the structural performance test, it was confirmed that the required load supporting capacity was secured. As a result of structural performance test for bar type anchor bolt and bent anchor anchor bolt, it was confirmed that the required load carrying capacity was secured and that the load bearing capacity of bent anchor bolt was large.

• Tissue Engineering and Regenerative Medicine
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• v.15 no.6
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• pp.735-750
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• 2018

BACKGROUND: The major challenge of tissue engineering is to develop constructions with suitable properties which would mimic the natural extracellular matrix to induce the proliferation and differentiation of cells. Poly(${\varepsilon}$-caprolactone)-poly(ethylene glycol)-poly(${\varepsilon}$-caprolactone) (PCL-PEG-PCL, PCEC), chitosan (CS), nano-silica ($n-SiO_2$) and nano-hydroxyapatite (n-HA) are biomaterials successfully applied for the preparation of 3D structures appropriate for tissue engineering. METHODS: We evaluated the effect of n-HA and $n-SiO_2$ incorporated PCEC-CS nanofibers on physical properties and osteogenic differentiation of human dental pulp stem cells (hDPSCs). Fourier transform infrared spectroscopy, field emission scanning electron microscope, transmission electron microscope, thermogravimetric analysis, contact angle and mechanical test were applied to evaluate the physicochemical properties of nanofibers. Cell adhesion and proliferation of hDPSCs and their osteoblastic differentiation on nanofibers were assessed using MTT assay, DAPI staining, alizarin red S staining, and QRT-PCR assay. RESULTS: All the samples demonstrated bead-less morphologies with an average diameter in the range of 190-260 nm. The mechanical test studies showed that scaffolds incorporated with n-HA had a higher tensile strength than ones incorporated with $n-SiO_2$. While the hydrophilicity of $n-SiO_2$ incorporated PCEC-CS nanofibers was higher than that of samples enriched with n-HA. Cell adhesion and proliferation studies showed that n-HA incorporated nanofibers were slightly superior to $n-SiO_2$ incorporated ones. Alizarin red S staining and QRT-PCR analysis confirmed the osteogenic differentiation of hDPSCs on PCEC-CS nanofibers incorporated with n-HA and $n-SiO_2$. CONCLUSION: Compared to other groups, PCEC-CS nanofibers incorporated with 15 wt% n-HA were able to support more cell adhesion and differentiation, thus are better candidates for bone tissue engineering applications.

• Design & Manufacturing
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• v.15 no.2
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• pp.11-16
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• 2021

Recently, three-dimensional (3D) cell culture systems, which are superior to conventional two-dimensional (2D) vascular systems that mimic the in vivo environment, are being actively studied to reproduce drug responses and cell differentiation in organisms. Conventional two-dimensional cell culture methods (scaffold-based and non-scaffold-based) have a limited cell growth rate because the culture cannot supply the culture medium as consistently as microvessels. To solve this problem, we would like to propose a 3D culture system with an environment similar to living cells by continuously supplying the culture medium to the bottom of the 3D cell support. The 3D culture system is a structure in which microvascular structures are combined under a scaffold (agar, collagen, etc.) where cells can settle and grow. First, we have manufactured molds for the formation of four types of microvessel-mimicking chips: width / height ①100 ㎛ / 100 ㎛, ②100 ㎛ / 50 ㎛, ③ 150 ㎛ / 100 ㎛, and ④ 200 ㎛ / 100 ㎛. By injection molding, four types of microfluidic chips were made with GPPS (general purpose polystyrene), and a 100㎛-thick PDMS (polydimethylsiloxane) film was attached to the top of each microfluidic chip. As a result of observing the flow of the culture medium in the microchannel, it was confirmed that when the aspect ratio (height/width) of the microchannel is 1.5 or more, the fluid flows from the inlet to the outlet without a backflow phenomenon. In addition, the culture efficiency experiments of colorectal cancer cells (SW490) were performed in a 3D culture system in which PDMS films with different pore diameters (1/25/45 ㎛) were combined on a microfluidic chip. As a result, it was found that the cell growth rate increased up to 1.3 times and the cell death rate decreased by 71% as a result of the 3D culture system having a hole membrane with a diameter of 10 ㎛ or more compared to the conventional commercial. Based on the results of this study, it is possible to expand and build various 3D cell culture systems that can maximize cell culture efficiency by cell type by adjusting the shape of the microchannel, the size of the film hole, and the flow rate of the inlet.