• 한국산학기술학회논문지
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• 제21권12호
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• pp.836-844
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• 2020

현대 사회는 장기 및 인체조직기증에 대한 요구도가 높아지고 있으나, 우리나라에서 인체조직기증에 대하여 인식도와 기증률이 낮아 기증 활성화를 위한 현실적인 방안에 대한 연구가 필요할 것으로 사료된다. 본 연구는 국내외 관련 문헌고찰 및 나라별 이식 등록기구 홈페이지 자료를 참조하여, 인체조직기증과 관련한 국내 법률과 운영 제도 현황을 분석하였으며, 해외 주요 국가와 비교 고찰하였다. 본 연구를 통하여 국내 인체조직기증 활성화 방안으로 법률적 측면에서 이원화된 장기와 조직이식에 관한 법체계의 통합화, 제도 운영적 측면에서 과도한 압력이 없는 국가의 장기기증에 대한 추정적 동의 방식인 Opt-out 제도의 활성화와 사회 문화적 측면에서 대국민 홍보 활성화를 제시하였다. 그러나 추정적 동의 방식은 다양한 사회적 공론화 단계가 필요하며, 거부 의사를 위한 등록체계 운영사항에 대해 국내 실정에 맞는 이해가 있어야 할 것이다. 결론적으로 외국에 비하여 낮은 장기 및 인체조직기증을 활성화하기 위한 법적 제도 정비가 요구되며, 기증에 대한 긍정적 인식 전환, 대중 홍보 및 사후 기증자와 가족에 대한 지원 등이 필요할 것으로 사료된다.

• 한국식품영양과학회지
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• 제37권7호
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• pp.834-840
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• 2008

호박 종실의 이용성을 증대시키기 위하여 호박 종실을 발아시켜 가면서 성장 중 고미성분의 성분분석을 행하고 고미물질을 순수 분리하여 정제하고 구조분석을 행하였다. 정제된 고미물질의 항염증 활성 및 폐암세포에 대한 암세포 성장 억제 활성을 측정한 결과는 다음과 같다. 호박 종실을 발아 시키면 종실에는 존재하지 않던 고미물질이 발아에 의하여 생성되므로 이 물질을 silica gel TLC, HPLC에 의하여 순수 분리한 결과 Rf 0.73, RT 10.3의 것을 모아 LC-MS/MS로 구조 분석을 행하여 분자량 557인 Cucurbitacin E(Cu E)로 확인되었다. 물 살포주기, 광, 온도를 달리하면서 발아시킨 호박씨의 고미성분인 Cu E 함량은 48시간 주기로 물을 살포하면서 $20^{\circ}C$, 암소에서 4일간 발아시켰을 때 224.7 mg/kg로서 최고치에 달하였다. 분리 정제한 Cu E는 in vitro에서 Cu E가 비교적 낮은 농도($1{\sim}100\;nM$)에서 1L-$1{\beta}$에 의한 염증성 COX-2 단백질 발현을 크게 감소시켰고, 비교적 높은 농도($1{\sim}5\;{\mu}M$)에서는 PMA에 의한 COX-2 단백질 발현 억제를 통한 항염증 활성을 보여주었다. 그리고 Cu E에 의한 A549 암세포의 증식 및 생존율에 미치는 영향을 확인한 결과 100 또는 1000 nM Cu E를 24 및 48시간 처리 시 약 $20{\sim}28%$ 및 $56{\sim}58%$의 A549 세포증식 억제 효과가 나타났고, 100 nM Cu E를 24시간 및 48시간 처리 시 약 60% 및 88%의 A549 세포생존율이 감소하였다.

• 종양간호연구
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• 제4권2호
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• pp.124-134
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• 2004

The major results of this study were as follows : 1. The percentage of nurses who know the complementary and alternative therapies was 50.1% Most of them(70.6%) acknowledged the therapies from newspapers, television and magazines. 2. The complementary and alternative therapy was perceived as effective by 64.9% of the nurses and as trusted by 60.2% of them The effective methods of the therapy are acupuncture herb medicine and massage. 3. Most of the nurses 93.4% experienced getting inquiries from patients or their guardians whether to use the therapies. 4. The complementary and alternative therapies was experienced by 38.9% of nurses and 7.1% of them use the therapies frequently 92.9% of patients and families were satisfied with the result 'Massage Therapy' was used the most with no side-effects and thus higher need of education for nurses. 5. They wanted to be trained for massage therapy finger-pressure, music therapy, acupuncture, aroma therapy in order. 6. Reliance on the complementary and alternative therapies, 75.2% of nurses completed the course trusted the therapies and the result of others uncompleted was similar as 52.2% Moreover both 79.5% of nurses completed it and 61.6% of the others said that the complementary and alternative therapy's nursing interventions is possible to develop. 7. It shows high relation to recognition having possibilities for applying and developing as the nursing intervention. if the confidence is as high as about the complementary and alternative therapies. Based of the results of this study as above this study proposes as follows. First, The nurses should understand mentality of the patients so that the nurses have to put in operation appropriate nursing intervention as accurate knowledge of the alternation therapies using to cancer patients for having on damages to patients from their rash using way. Furthermore, it is necessary to supply the special place and the professional nurses taking complete charge at them. Next politic interest and support from government are required to develop and practice systematic and resonable education programs for the complementary and alternative therapies. Moreover, it is necessary for nurses to be educated about the therapies continually. Finally, it is compulsory that the research and development for complementary and alternative therapies is needed. In addition, it has to be made standard and legal equipment for safety efficacy and theory about the therapies.

• Asian-Australasian Journal of Animal Sciences
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• 제27권1호
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• pp.46-54
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• 2014

This study was conducted to investigate the effects of eucalyptus (E. Camaldulensis) crude oils (EuO) supplementation on voluntary feed intake and rumen fermentation characteristics in swamp buffaloes. Four rumen fistulated swamp buffaloes, body weight (BW) of $420{\pm}15.0$ kg, were randomly assigned according to a $2{\times}2$ factorial arrangement in a $4{\times}4$ Latin square design. The dietary treatments were untreated rice straw (RS) without EuO (T1) and with EuO (T2) supplementation, and 3% urea-treated rice straw (UTRS) without EuO (T3) and with EuO (T4) supplementation. The EuO was supplemented at 2 mL/h/d in respective treatment. Experimental animals were kept in individual pens and concentrate mixture was offered at 3 g/kg BW while roughage was fed ad libitum. Total dry matter and roughage intake, and apparent digestibilites of organic matter and neutral detergent fiber were improved (p<0.01) by UTRS. There was no effect of EuO supplementation on feed intake and nutrient digestibility. Ruminal pH and temperature were not (p>0.05) affected by either roughage sources or EuO supplementation. However, buffaloes fed UTRS had higher ruminal ammonia nitrogen and blood urea nitrogen as compared with RS. Total volatile fatty acid and butyrate proportion were similar among treatments, whereas acetate was decreased and propionate molar proportion was increased by EuO supplementation. Feeding UTRS resulted in lower acetate and higher propionate concentration compared to RS. Moreover, supplementation of EuO reduced methane production especially in UTRS treatment. Protozoa populations were reduced by EuO supplementation while fungi zoospores remained the same. Total, amylolytic and cellulolytic bacterial populations were increased (p<0.01) by UTRS; However, EuO supplementation did not affect viable bacteria. Nitrogen intake and in feces were found higher in buffaloes fed UTRS. A positive nitrogen balance (absorption and retention) was in buffaloes fed UTRS. Supplementation of EuO did not affect nitrogen utilization. Both allantoin excretion and absorption and microbial nitrogen supply were increased by UTRS whereas efficiency of microbial protein synthesis was similar in all treatments. Findings of present study suggested that EuO could be used as a feed additive to modify the rumen fermentation in reducing methane production both in RS and UTRS. Feeding UTRS could improve feed intake and efficiency of rumen fermentation in swamp buffaloes. However, more research is warranted to determine the effect of EuO supplementation in production animals.

• 지역사회간호학회지
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• 제5권2호
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• pp.130-146
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• 1994

Our medical care system is trying to diversify in order to meet the client's needs, and to adjust to a medical environment which is changing very rapidly. Because current nursing theory and practice focus on holistic care, health care management, education, and research, contrary to the traditional emphasis on only assisting a physician, more autonomy and specialization for the implementation of nursing are required. Considering these trends and actual needs, the category of clinical nurse specialist should be established as soon as possible. In order to develop strategies for implementing this new professional specialty, the authors conducted a field survey and literature review of the current system in Korea. As a result, various obstacles and constraints were discovered as follows : 1) There are few accredited educational programs for the training of CNS's. 2) Several hospitals already have staff designated as clinical nurse specialist (CNS) even though the term CNS is not yet standardized or adopted in nationwide. 3) The role of the CNS is not clearly understood by the medical societies, or even nursing societies. A nurse who works in specific nursing areas such as central supply, kidney dialysis, intensive care, coronary care, etc. for a long time, considers herself /himself a CNS. Based upon the above findings, the following alternatives are recommended. 1) The role of the CNS should be defined according to specified functions and authority : professional autonomy ; counselling and educating patients and their familes, nurses, and even other medical personnel ; research on improvement of nursing ; and management of the nursing environment including medical resources, information, and cases. 2) the qualification of CNS should be attained only by a nurse who has an RN license and clinical experience of more than 3 years in a specific nursing field: passes a qualifying examination; and contributes to the professional development of peers, colleagues, and others. A master's degree should only be optional, because of the insufficient of graduate programs which are well designed for the CNS. 3) The CNS should initially be a head nurse rather than line staff in order to deal with as wide an experience base as possible. 4) The nursing specialty could be divided into two areas such as a clinical field and a community field. The clinical field could then be categorized by the Styles' classification such as diseases and pathogenics, systems, ages, acuity, skills/techniques, and function/role ; the community field could be classified according to work site.

• 한국콘텐츠학회논문지
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• 제10권8호
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• pp.266-273
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• 2010

본 연구는 예비 구강보건 인력인 치위생과 학생들을 대상으로 취업 후 직면할 수 있는 의료시장 개방에 대한 부정적인 측면과 긍정적인 측면에 대한 이해를 도와 의료시장 개방과 관련된 문제점을 대처할 수 있도록 하였다. 연구결과는 의료시장개방에 따른 국내 병원의 경영위기의 원인으로 '병원 경영기법의 한계' 38.1%,로 가장 높게 나타났으며, 개방에 대한 찬성의 가장 큰 이유는 '의료에 대한 환자의 선택권 확대' 50.7%로 가장 높게 나타났다. 또한 개방의 반대 이유는 '중소병원의 경쟁력 상실'이 30.3%로 가장 큰 이유를 보였다. 또한 보건의료관련 기사에 관심이 많은 경우 의료시장개방 찬성이 62.2%(p<0.001)로 통계적으로 유의한 차이를 보였으며, 의료시장 개방에 따른 영향과 찬반의견에서는 '의료기술의 수준 향상', '의료기술의 수준 향상', '국민부담 의료비 감소', '의료시설의 공급확대', '의약품 및 의료기기 산업 활성화'에서 유의한 차이를 보이고 있다(p<0.00). 의료시장 개방에 따른 위기의식 유무에서는 찬성인 경우 '없다' 55.6%, 반대하는 경우 '있다' 52.3%로 통계적으로 유의한 차이를 보였다(p<0.003) 이결과 의료시장 개방에 대한 인식도가 낮은 편이며 학생들이 의료시장 개방과 관련된 내용에 보다 많은 관심을 갖도록 다양한 방법이 모색되어야 할 것이다.

• 재활간호학회지
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• 제4권1호
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• pp.58-72
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• 2001

A Cerebrovascular accident(CVA), or Stroke is a medical emergency that occurred when the blood supply to the brain is interrupted or blocked. The stroke causes physical function disorder due to hemiparalysis and emotional disorder. Also the stroke patients experience helplessness, powerlessness, sense of alienation and loss of hope. These feelings make the rehabilitation difficult because they lose the will of life. The purpose of this study is to identify the correlation between perceived social support and hope of stroke survivors. The subjects for this study were 100 out-patients with stroke in one general hospital and oriental medicine hospital located in Mokpo. The data were analysed by frequency, t-test, ANOVA. Duncan test, Pearson's correlation, using the SPSS WIN 9.0 program. Data were collected from July 11 to September 9, 2000, using a structured questionnaire. The instruments used for this study : The social support scale developed by Park, Ji-won(1985) and the hope scale developed by Miller(1988). The results were as follows. 1. It was found that the higher the degree of perceived social support, the higher the degree of hope(r=.726, p=.000). Therefore hypothesis was supported. 2. The mean score of perceived social support was 77.8(SD=21.0) with a score range from 27.0 to 104.0. 3. The mean score of perceived hope was 117.0(SD=25.7) with a score range from 57.0 to 160.0. 4. The level of social support depending on general characteristics were significantly different in variables such as marital status(t=3.131, p=.010). degree of income satisfaction(F=16.027, p=.000). 5. The level of hope depending on general characteristics were significantly different in variables such as marital status(t=2.681, p=.040). current job(t=-2.055, p=.043) degree of income, satisfaction(F=11.363, p=.000). For these subjects, there was a significant relationship between social support and hope. The stroke survivors need social support to inspire their hope. Nurses should plan interventions to enhance social support for patients with stroke. The above results may be used as the basic data to seek more efficient way of elevating nursing practice and rehabilitation for the patients with stroke.

• Journal of Applied Biological Chemistry
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• 제52권4호
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• pp.200-204
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• 2009

멜론의 가공방안을 높이고, 안정된 수급과 식품소재로 활용하기 위해 냉동저장과 추출방법에 따른 생리활성 변화를 조사하였다. 냉동저장기간(3, 6개월)에 따른 멜론의 총 phenol 함량은 멜론즙이 $296.25\;{\mu}g/mL$, 열수추출물은 $433.25\;{\mu}g/mL$로 나타났다. 또한 총 flavonoid성 함량은 멜론즙이 $20.83\;{\mu}g/mL$로 나타났고, 열수추출물은 $53.58\;{\mu}g/mL$로 나타났고, 냉동저장기간 동안 총 phenol 함량과 총 flavonoid성 함량은 비교적 차이가 없었다. 멜론의 항산화 효과는 전자공여능이 멜론즙과 열수추출물이 각각 60.58%, 85.84%로 나타났고, ABTS는 각각 94.50%, 99.30%로 높게 나타났다. SOD 유사활성은 열수추출물이 27.5%인 반면 멜론즙의 경우 거의 효과를 나타내지 않았다. Xanthine oxidase의 저해활성의 경우 멜론즙이 41.76%, 열수추출물은 61.29%로 높은 저해율을 나타내었고, 열수추출물이 다소 높게 나타났다. $\alpha$-Glucosidase 저해활성은 멜론즙이 22.42%, 열수추출물은 23.43%로 비교적 유사한 저해율을 나타내었다. 냉동기간에 따른 항산화 효과는 비교적 차이가 없었다. 이러한 결과로 냉동 저장 시 항산화활성의 차이가 거의 없음으로 연중 원료의 안정적인 수급과 식품소재로 활용이 가능할 것으로 사료된다.

• 지역사회간호학회지
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• 제11권2호
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• pp.399-410
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• 2000

In this, analyzing the type of subjectivity in which people would have about home visit nursing services originating from public health care centers. I tried to research more effective ways to improve home visit nursing care services. and later. for the development of home visit nursing care. to supply basic data. The method for this study was the Q-method. created by William Stephenson. and was adequate for the study of subjectivity. For this study. through the deep interview. literature inquiry, and the discussion course. 206 Q-statement sentences were abstracted. and based on them, after Q-sample-selection. I then collected the Q-categorized-result from 32 subjects from Mar. 10. 2000 to Mar. 25. 2000. Through the statistic a analysis of PC-Qunal program. the subjectivity species were categorized and analyzed. The study results show that there are 3 sorts of recognition types. and they are analyzed in the following; The first type: the positively receiving type shows that they feel thankful and a trusting feeling about home visit nursing. The second type: the negatively mistrusting type shows that they had doubtful attitudes about the specialty of home visit nursing: they wanted medicine or nutrition remedies rather than health education and concerning the their own health care, they prefered the hospitals or clinics. The third type: the conditional receiving type shows that even though they had a positive receiving attitude about home visit nursing wanting to consult with the home visit nurses about the difficult problem which could not easily be settled, hoping that the home visit nurses could visit them more often, in their actual lives. they strongly indicated their attitudes concerning money as more important than home visits. The subjects in these 3 types commonly had a good feeling about the kindness of the home visit nurses: the first and third types also had a positive recognition about home visit nursing; however. in aspects of the evaluation and receiving attitudes, they showed a big difference. When all the above results are integrated. in the case of the first type the home visit nursing service, which satisfied the demand for health care of the medically weak people. should be continuously supplied. Additionally in case of the second type (negatively mistrust). continuous education and support should be supplied with enough interest to lead their concerns about their own health care as well as lead medical spending in a productive and effective direction in order to change their impressions. Through this study. I learned that the recognition of the objectives of home visit nursing services can be categorized in to 3 types and could be analyzed. Thus I wish that this study helps to present basic data which contributes to the development of the home visit nursing field.

• 생명과학회지
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• 제17권12호
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• pp.1734-1738
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• 2007

딸기의 가공방안을 높이고, 안정된 수급과 식품소재로 활용하기 위해 냉동저장과 추출방법에 따른 생리활성 변화를 조사하였다. 냉동저장기간(3, 6개월)에 따른 딸기의 총 phenol 함량은 딸기즙이 $2.342{\mu}g/ml$. 열수추출물은 $2.235{\mu}g/ml$로 나타났다. 반면, 총 flavonoid성 함량은 딸기즙은 $200.36{\mu}g/ml$로 나타났고, 열수추출물은 $201.07{\mu}g/ml$로 나타났고, 냉동저장기간 동안 총 phenol 함량과 총 flavonoid성 함량은 비교적 차이가 없었다. 딸기의 항산화 효과는 전자공여능이 딸기즙과 열수추출물이 각각 94.2%, 93.5%로 나타났고, ABTS는 각각 99.9%, 100%로 높게 나타났다. Xanthine oxidase의 저해활성의 경우 딸기즙이 93.0%, 열수 추출물은 99.9%로 높은 저해율을 나타내었고, 열수추출물이 다소 높게 나타났다. SOD 유사활성은 딸기즙과 열수추출물이 32.5%, 38.0%로 열수추출물이 비교적 높은 SOD유사활성을 나타내었고, 냉동기간에 의한 항산화 효과는 비교적 차이가 없었다. 이러한 결과로 냉동 저장 시 항산화활성의 차이가 거의 없음으로 연중 원료의 안정적인 수급과 식품소재로 활용이 가능할 것으로 사료된다.