• Title/Summary/Keyword: Sun Ginseng

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The Effect of Sun Ginseng on Hemodynamics and Body Temperature in Healthy Young Men

  • Lee, Jeeh-Wan;Cho, Jung-Ah;Ki, Chan-Young;Park, Jeong-Hill;Park, Man-Ki
    • Proceedings of the PSK Conference
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    • 2003.04a
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    • pp.317.2-318
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    • 2003

  • The current study was performed to observe the effect of Sun Ginseng (SG) on hemodynamics such as blood flow rate (BF), blood flow velocity (BV), heart rate (HR), systolic blood pressure (SBP) and diastolic blood pressure (DBP), and body temperature (BT) in healthy young men. This is a randomized, single-blind study observed during 6 hrs after orally single administration of SG. (omitted)

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Effect of Extraction Temperature and Ethanol Concentration on Nitrogeneous Constituents of Red Ginseng Extract (추출조건이 홍삼엑기스의 질소화합물 조성에 미치는 영향)

  • Seong, Hyeong-Sun;Kim, U-Jeong;Yang, Cha-Beom
    • Journal of Ginseng Research
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    • v.9 no.1
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    • pp.95-103
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    • 1985

  • The concentrated red ginseng extract (RG-EXT) was prepared by extracting the ginseng tails with 0-90% ethanol solution at 70-100$^{\circ}C$ and analyzed for amino acids composition and other nitrogeneous fractions. The results showed that nonprotein fraction was more than 90% of the total N-compounds and 17 free amino acids were identified by High Performance Liquid Chromatography. Maximum and minimum N-compounds or total free amino acids were recovered in RG-EXT with 50% and 90% ethanol, respectively. An increase in ethanol concentration resulted a significant change in free amino acid composition while extraction temperature caused a little gradual decrease in water soluble nonprotein and total nitrogen fractions.

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Effects of Ginseng Saponin on Modulation of Multidrug Resistance

  • Park, Jong-Dae;Kim, Dong-Sun;Kwon, Hyeok-Young;Son, Sang-Kwon;Lee, You-Hui;Baek, Nam-In;Kim, Shin-Il;Lee, Dong-Kwon
    • Archives of Pharmacal Research
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    • v.19 no.3
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    • pp.213-218
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    • 1996

  • Multidrug resistance (MDR) has been a major problem in cancer chemotherapy. To overcome this problem, we prepared minor ginsenosides stereoselectively from ginseng saponins and searched for a ginseng component which is effective for inhibition of MDR. MDR inhibition activity was determined by measuring cytotoxicity to MDR cells using multidrug resistant human fibrocarcinoma KB V20C, which is resistant to 20 nM vincristine and expresses high level of mdr1 gene. Of several ginseng components, 20(S)-ginsenoside Rg_3$, a red ginseng saponin, was found to have the most potent inhibitory activity on MDR and it's concentration capable of inhibiting 50% growth was $82\muM$.

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