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Changes in Cytomegalovirus Seroprevalence in Korea for 21 Years: a Single Center Study

  • Choi, Sae Rom;Kim, Kyung-Ran;Kim, Dong Sub;Kang, Ji-Man;Kim, Sun Ja;Kim, Jong Min;Oh, Soo-young;Kang, Choel-In;Chung, Doo Ryeon;Peck, Kyong Ran;Kang, Eun-Suk;Kim, Yae-Jean
    • Pediatric Infection and Vaccine
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    • v.25 no.3
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    • pp.123-131
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    • 2018
  • Purpose: Cytomegalovirus (CMV) infection is mostly asymptomatic but can be detrimental to certain hosts. We investigated changes of CMV seroprevalence in Koreans before and after the year 2000. Methods: We reviewed laboratory values of patients who were tested for CMV immunoglobulin G (IgG) at Samsung Medical Center, Seoul, Korea, from January 1995 to December 2015. Changes in seroprevalence were analyzed by gender, age, region, and tested year period (period 1, 1995-2005 vs. period 2, 2006-2015). Results: Overall CMV seropositivity was 94.1% (10,900/11,584). There was no significant difference for CMV seropositivity among the two periods (94.2% vs. 94.1%) (P=0.862). CMV seropositivity in the 11 to 20-year age group in period 2 (78.8%) was significantly lower than that of period 1 (89.9%) (P=0.001). The seropositivity of individuals aged 31-40 years (97.4%) was significantly higher than that of younger age groups (P<0.001) and lower than that of older age groups (P<0.001). Of 2,441 females of reproductive age (from 15 to 49), CMV seropositivity was 97% (2,467/2,441). The seropositivity in women aged 20-24-years was higher than that of men in the same age group (97.6% vs. 85.6%, P=0.003). No significant difference was observed among different regions. Conclusions: Overall CMV seropositivity of Koreans was estimated to be 94% and the average seropositivity of reproductive women was 97%. Monitoring of the changes in seroprevalence including the reproductive age group is needed in the future.

Validation of Electronic Foot Function Index in Patients with Foot and Ankle Disease: A Randomized, Prospective Multicenter Study (족부 족관절 질환 환자에서 전자식 족부 기능 지수의 인증: 임의 배정, 전향적, 다기관 연구)

  • Lee, Dong Yeon;Kim, Yu Mi;Lee, Jun Hyung;Kim, Jin;Kim, Ji-Beom;Kim, Bom Soo;Choi, Gi Won;Seo, Sang Gyo;Kim, Jun Beom;Park, Se-Jin;Kim, Yoon-Chung;Choi, Young Rak;Lee, Dong-Oh;Cho, Jae-Ho;Chun, Dong-Il;Kim, Hyong Nyun;Park, Jae-Yong
    • Journal of Korean Foot and Ankle Society
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    • v.23 no.1
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    • pp.24-30
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    • 2019
  • Purpose: To evaluate the efficiency of the electronic foot function index (eFFI) through a prospective, random based, multi-institutional study. Materials and Methods: The study included 227 patients ranging in age from 20 to 79 years, visited for surgery in different 15 institutes, and agreed to volunteer. The patients were assigned randomly into a paper-based evaluated group (n=113) and tablet-based evaluated group (n=114). The evaluation was done on the day of hospital admission and the method was changed on the second day of surgery and re-evaluated. PADAS 2.0 (https://www.proscore.kr) was used as an electronic evaluation program. Results: There were no differences in age and sex in both groups. The intraclass correlation coefficient (ICC) evaluation revealed an eFFI ICC of 0.924, showing that both results were similar. The evaluation time was shorter in the tablet-based group than the paper-based group (paper vs tablet, $3.7{\pm}3.8$ vs $2.3{\pm}1.3minutes$). Thirty-nine patients (17.2%) preferred to use paper and 131 patients (57.7%) preferred the tablet. Fifty-seven patients (25.1%) found both ways to be acceptable. Conclusion: eFFI through tablet devices appears to be more constant than the paper-based program. In addition, it required a shorter amount of time and the patients tended to prefer the tablet-based program. Overall, tablet and cloud system can be beneficial to a clinical study.

The Collection of Paintiongs and Calligraphy at Jipgyeong-dang Hall during King Gojong's Reign(1897~1907) (고종연간 집경당(緝敬當)의 운용과 궁중(宮中) 서화수장(書畵收藏))

  • Hwang, Jung-yon
    • Korean Journal of Heritage: History & Science
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    • v.40
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    • pp.207-241
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    • 2007
  • This paper investigates the royal collection of paintings and calligraphy during King Gojong's (高宗) reign (1897~1907) based on the function of the Jipgyeong-dang Hall (緝敬堂), situated at "sleeping realm (寢殿)," Gyeongbok Palace. Using the surviving palace records and art works this study argues that the date of building the hall is approximately confined to the year of 1890. Not being matched with the general opinion that the Jipgyeong-dang Hall was used for the official meeting with envoys, this hall functioned as the main place for royal audience and the storehouse for archives. The role of Gojong as collector and patron was essential not only to the maintenance of the collection but also to the strengthening of royal authority just before the Japanese annexation in 1910. The specific titles of the collection at this hall can be verified through the Catalogue of the Books, Paintings, and Calligraphy Exposed to the Sun at Jipgyeong-dang Hall (緝敬堂曝曬書目) dating to the nineteenth century. The records of the catalogue inform us that more than 1,000 paintings and pieces of calligraphy, inkrubbings from old steles, manuals for painting, and encyclopedia concerning art theories from Korea, China, and Japan were preserved there. The collection of Jipgyeong-dang Hall resulted from Gojong's policy to foster the collection of contemporary Chinese and Japanese art works and various catalogues. Standing behind the Gyeongbok Palace, the Jibok-jae Hall (集玉齋) also preserved the diverse sources of practical learning, as did the Jipgyong-dang Hall for Gojong. The enormous royal collections by Gojong might have been constructed in accordance with the royal artistic taste and the artistic milieu of the late Joseon period. The surviving royal catalogues confirm this assumption as documentary evidence.

Study of Nutrient Analysis by Specie of Domestically Cultivated Popcorns (국내 육성 팝콘 옥수수 품종별 영양성분 분석 연구)

  • Park, A Reum;Lee, Ki Yeon;Kim, Tae Hee;Choi, Jae Geun;Lee, Hyo Young;Choi, Sung Jin;Kwon, Sun Bae;Kim, Hee Yeon
    • Journal of Food Hygiene and Safety
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    • v.34 no.5
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    • pp.438-446
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    • 2019
  • In this study, the nutrients of a total of 4 species of popcorn, Oryun Popcorn, Oryun Popcorn 2, G-Popcorn and Gichan Popcorn, cultivated in Gangwon-do, were analyzed and compared. The contents of these products, including their general ingredients, inorganic substances, fatty acids, reducing sugar and starch, were analyzed. The moisture, crude ash and crude fat content of the dried popcorn species were 11.54-12.54%, 0.97-1.45% and 2.48-2.62%, respectively. The crude protein content was 9.68-11.75%. As for inorganic substances, the potassium and phosphorus content were the highest. Potassium was 228.25-310.46 mg/100g and was the highest in Oryun Popcorn, and the content of phosphorus was 276.04-310.00 mg/100g. As for fatty acids, 11 types were detected. The content of linoleic acid accounted for 52.89-55.76% of the total fatty acid content showing the highest amount followed by oleic acid (24.31-26.65%) and palmitic acid (14.20-15.92%). As for amino acids, total 16 types of amino acids were detected by specie, with glutamic acid making up 17.70-18.52% of total amino acids, the highest, followed by leucine (12.30-12.54%) and proline (10.34-10.92%) in that order. The creducing sugar content by specie was 4.68-5.13% and starch content was 42.14-46.14%.

Characteristics of Growth and Seedling Quality of 1-Year-Old Container Seedlings of Quercus myrsinaefolia by Shading and Fertilizing Treatment (피음 및 시비처리에 따른 가시나무 1년생 용기묘의 생장과 묘목품질 특성)

  • Sung, Hwan In;Song, Ki Sun;Cha, Young Geun;Kim, Jong Jin
    • Journal of Korean Society of Forest Science
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    • v.100 no.4
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    • pp.598-608
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    • 2011
  • The purpose of this study was to examine potential effects of shading and fertilizing treatment - two basic applicable factors in production of 1-year-old container seedling - on growth and seedling quality of Quercus myrsinaefolia, one of evergreen tree species in warm temperate zone of Korean. Every experimental process was conducted in a facility that consisted of compartments under the lighting control with full sunlight and shading (35%, 55% and 75% of full sunlight). Based on fertilizing treatment, this study made an experiment in 4 groups of container seedling: control (non-treated seedlings) and 1000, 2000, 3000 ppm group (3 groups with different concentrations of water-soluble fertilizer (N:P:K=19:19:19, v/v). Seedlings under 55% shading with 2000 ppm concentration showed the highest height (totaling 21.1 cm), and under 35% shading with 2000 ppm concentration showed the highest root collar diameter growth (totaling 3.96 mm) among others. All three fertilizing groups except control showed H/D ratio ranging from 4.27 to 5.26 regardless of fertilizer concentration under 35% and 55% shading where container seedlings showed a tendency toward excellent growth of height and root collar diameter. Overall, 2000 ppm group under 55% shading showed highest dry mass production of leaves (1,292 g) among others, while 2000 ppm group under 35% shading showed highest dry mass production of shoots and roots (0.592 g and 0.998 g, respectively) among others. Also, it was found that 2000 ppm group under 35% shading showed the highest dry mass production of whole seedling, which was followed by 2000 ppm group under 55% shading and 3000 ppm group under 35% shading, respectively. According to analysis on LWR of Quercus myrsinaefolia depending on shading and fertilizing treatment, it was found that 3000 ppm group under 75% shading showed highest LWR level among others, whereas every fertilized group showed lower RWR level than control without fertilizing regardless of shading levels. In general, all fertilized groups under 55% shading had relatively high quality index (QI), and 2000 ppm group under 35% shading had highest QI among others. Based on the findings of this study, it is concluded that shading level ranging from 35 to 55% and fertilizing concentration of 2,000 ppm are suitable for producing 1-year-old container seedlings of Quercus myrsinaefolia with excellent growth and high quality index.

Current status and tasks of the transmission of Gyeonggi Province intangible cultural assets (folk songs) (경기도 향토민요 관련 무형문화재의 전승현황과 과제)

  • Jang, hee-sun
    • (The) Research of the performance art and culture
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    • no.35
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    • pp.405-439
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    • 2017
  • In this article, I suggest issues and tasks in transmission of Gyeonggi Province folk songs after thorough study of designation of Gyeonggi Province folk songs as intangible cultural asset, reproduction and transmission. Intangible cultural assets are classified into seasonal playing and songs. Originally, category or extension of folk songs is above mere songs and it also embraces personal lives as well as village communities. Intangible assets of folk songs are folk art, group events and non-stage events at the same time based on tradition, history, uniqueness, characters of field value. Gyeonggi Province has 9 intangible assets now because of the revocation of several assets (All Gyeonggi Province, Hwasung, Gwacheon) within five years after initial designation of 13 assets in 1998. They are mostly distributed in the north Gyeonggi region where is close to the DMZ and delay in development seems to have enabled the preservation. Most of the intangible cultural assets are farming songs and weeding which show characteristics of Gyeonggi Province. Most of the designees are who performed excavation, recovery, excluding a few cases without designees on designation, and almost all the designee passed away. Number of cases have been revoked because transmission was not completed or some cases were transmitted to groups rather than specific designees. Subscription concert, the biggest and most representative event, is performed once a year with all of the 9 intangible cultural assets in the original complete forms of the designation. Intangible cultural assets are classified into seasonal playing and songs. In general, current performance of the intangible cultural assets and folk songs are same as the originally designated forms and are not in varied forms other than folk songs like songs for rice-planting and weeding. Funeral songs are transmitted in Yangju and Yangpyeong. In terms of the operation, preservation societies having training centers have been performing more constant activities for preservation including lecture, performance and transmission. Members are quite aged and the societies are suffering from lack of support fund for reproduction and transmission. Problems in reproduction and tasks for the transmission I would like to suggest are like followings. First, preservation and value of the cultural assets. Second, new understanding of designation and revocation of the intangible cultural assets. Third, record of performance and sound source. Fourth, liaison with local communities. Fifth, organization of professional resources and establishment of systematic support and management.

Management of Naturalized Citizens from Yeozin and Its Limitation Through the Event of Guilsang(吉尙) in the Early 17th Century - Centering on 『Naturalization Registration』 (길상사건(吉尙事件)을 통해 본 17세기 초 향화호인(向化胡人) 관리 실태와 한계 - 『향화인등록(向化人謄錄)』을 중심으로 -)

  • Yi, Sun Hui
    • (The)Study of the Eastern Classic
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    • no.37
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    • pp.93-126
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    • 2009
  • This study is about a event, which happened on January of 1603 in Hamheung. It has covered from the beginning through the conclusion of the event. The event was ignited by a naturalized citizen, Guilsang's coming to the capital city without permission from the government. With this study I've wished to find the situations of specific management of naturalized citizens as well as popular attitudes towards them at the time. Concerning with the event of Guilsang, I could find more detailed situations from "Naturalization Registration". The reason why Guilsang came to Seoul was that he wanted to ask for living together with his son-in-law's family in Yang-Ju. Before his coming, Bie-Byun-Sa had sent a official letter to the governor of Hamkyung-Do so that he had had to move somewhere between Anbyun and Yung-heung. But Guilsang had wanted to live with his whole family in Seoul. The place he visited first was Sa-Yuk-Won. He presented his petition through Yeozin language translator there. Sa-Yuk-Won then informed Ye-Jo to have him investigated. After its investigation, Ye-Jo reported to the king. There were arguments about Guilsang family in the government. Guilsang had wanted to live with his whole family, including his relatives and son-in-law. Guilsang's request had more pros than cons in terms of humanism. But letting him live in Seoul was a difficult decision for the government. but his family strenuously insisted on living in Seoul, trying to kill itself. Finally Government selected Yong-In which was a compromise between the naturalized citizens' wish and difficult position of Government. Yong-In Miejo-Hyun was a poor region where naturalized citizens had lived before but now empty after the wars. In the process of the event of Guilsang, Government differentiated naturalized citizens from general citizens and regarded them foreign. A man from Yeozin was naturalized due to economic reason. But, he couldn't accept to live somewhere except Seoul, separating from his family. Government concerned with dangers of naturalized citizen becoming into foreign agents and stabilization of borders. These concerns caused the policy of residential control and decentralization of naturalized citizens failed.

A Study on Conventional Expression of Hangul Ganchal and Email (조선시대 한글 간찰과 이메일의 상투적 표현 고찰)

  • Jeon, Byeong-yong
    • (The)Study of the Eastern Classic
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    • no.49
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    • pp.431-459
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    • 2012
  • The purpose of this article is to compare and analyze the conventional expression of Hangul Ganchal in Cheosun Dynasty and Email. Conventional expression is used remarkably in introductions and conclusions. In introduction, it is used for addressing and safety greetings while in conclusion, it is used for closing address and closing words. In Cheosun Dynasty, an envelope of Ganchal only included the details of the receiver because the letter was genuinely delivered by someone who knew the receiver and the sender very well. An envelope of Ganchal is applicable to the screen of the internet which is used for emailing. In an email, we see the name of the sender and the title of the text and once we click the title, we are able to view the text. The difference between the Ganchal and the email was reflected on how the receiver's detail showed on Ganchal and the email show the sender's details. In a case of addressing in a letter while using the conventional expression, we can see how we use "To~" in humble term and " ~께" in a honorific term. We confirmed that the conventional expression has not yet settled in both of the Gnachal and email for the seasonal greetings. The safety greetings comprised with both of the senders' and receivers' latest updates. In Ganchal, this composition is well described conventionally, whereas in emails, only the receivers' latest news are written but the senders' latest updates are hard to be seen throughout the text. In Ganchal's closing section, the closing address and closing words were expressed conventionally. However, in the case of email; those were again hard to be found throughout. To conclude, in Ganchal the conventional expression was developed and placed in 16thcentury(Sun-eon) when there was a focus in our native language. In 17thcentury(Hyeon-eon), it stood still for a sometime and moved on to 19thcentury(Jing-eon) when there was a strong in fluence of Hangul Ganchal, which resulted in regression to the conservative expression. In general, we are able to confirm that the conventional expression is slowly disappearing.

Characteristic of Personnel Organization and Facility of Gyeonggi Kamyoung during Late Joseon (조선후기 경기감영의 인원 구성과 시설 특징)

  • YI, SUN HUI
    • (The)Study of the Eastern Classic
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    • no.73
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    • pp.185-217
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    • 2018
  • This research is a part of basic research on Gyeonggi Kamyoung focused on reconstruct personnel organization and facility of Gyeonggi Kamyoung, the only Kamyoung without a Kamyoung Record, which should have been recorded on it. Excluding Gyeonggi Kamyoung, other 7 Kamyoung each have its Kamyoung Record that shows their detailed history and set up. Due to lack of information about Gyeonggi Kamyoung, this research set objective on reconstructing Kamyoung Record of it with fragments of information on multiple historical records. By doing this, this research will also be a background for general research on distinguishing administrative unity from regional uniqueness of all 8 provinces Kamyoung. Kamyoung's personnel organization is sorted into government official from central government and Yeongli and staff. The information about the government official on this research is based on "Ki-Yung-Jang-Gae- Deung-Rok"'s personal assessment. According to it, Dosa Junggun Geomlyul had the same task and position as others in different provinces did. The difference Gyeonggi Kamyoung had was an absence of Sim Yak since 1700 while others still had it. The information about Yeongli and staff's organization was based on "Ki-Yeong-Sin-Jeong-Sa-Le". In Gyeonggi Kamyoung, along 6-Bang, there were 208 Yeongli and staff categorized into 50 different official duties. Also, compared to other Kamyoungs, Youngli's scale was smaller. Kamyoung's facility inside Pojeongmun and wall is distinguished from other Kamyoung related facilities in this research. Organization of facilities inside Pojeongmun and wall is based on "Gyeonggi-Kamyoung-Do". Like other Kamyoungs in different provinces, Seonhwadang, which is the main building, is located in the center and had a similar organization. Significant point was that Gyeonggi Kamyoung had both Youngli-Cheong and Hyeongli-Cheong at the same time. In the dense and developed area outside of Seodaemun, Gyeonggi Kamyoung had its related facility around it in small scale.

Performance of Investment Strategy using Investor-specific Transaction Information and Machine Learning (투자자별 거래정보와 머신러닝을 활용한 투자전략의 성과)

  • Kim, Kyung Mock;Kim, Sun Woong;Choi, Heung Sik
    • Journal of Intelligence and Information Systems
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    • v.27 no.1
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    • pp.65-82
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    • 2021
  • Stock market investors are generally split into foreign investors, institutional investors, and individual investors. Compared to individual investor groups, professional investor groups such as foreign investors have an advantage in information and financial power and, as a result, foreign investors are known to show good investment performance among market participants. The purpose of this study is to propose an investment strategy that combines investor-specific transaction information and machine learning, and to analyze the portfolio investment performance of the proposed model using actual stock price and investor-specific transaction data. The Korea Exchange offers daily information on the volume of purchase and sale of each investor to securities firms. We developed a data collection program in C# programming language using an API provided by Daishin Securities Cybosplus, and collected 151 out of 200 KOSPI stocks with daily opening price, closing price and investor-specific net purchase data from January 2, 2007 to July 31, 2017. The self-organizing map model is an artificial neural network that performs clustering by unsupervised learning and has been introduced by Teuvo Kohonen since 1984. We implement competition among intra-surface artificial neurons, and all connections are non-recursive artificial neural networks that go from bottom to top. It can also be expanded to multiple layers, although many fault layers are commonly used. Linear functions are used by active functions of artificial nerve cells, and learning rules use Instar rules as well as general competitive learning. The core of the backpropagation model is the model that performs classification by supervised learning as an artificial neural network. We grouped and transformed investor-specific transaction volume data to learn backpropagation models through the self-organizing map model of artificial neural networks. As a result of the estimation of verification data through training, the portfolios were rebalanced monthly. For performance analysis, a passive portfolio was designated and the KOSPI 200 and KOSPI index returns for proxies on market returns were also obtained. Performance analysis was conducted using the equally-weighted portfolio return, compound interest rate, annual return, Maximum Draw Down, standard deviation, and Sharpe Ratio. Buy and hold returns of the top 10 market capitalization stocks are designated as a benchmark. Buy and hold strategy is the best strategy under the efficient market hypothesis. The prediction rate of learning data using backpropagation model was significantly high at 96.61%, while the prediction rate of verification data was also relatively high in the results of the 57.1% verification data. The performance evaluation of self-organizing map grouping can be determined as a result of a backpropagation model. This is because if the grouping results of the self-organizing map model had been poor, the learning results of the backpropagation model would have been poor. In this way, the performance assessment of machine learning is judged to be better learned than previous studies. Our portfolio doubled the return on the benchmark and performed better than the market returns on the KOSPI and KOSPI 200 indexes. In contrast to the benchmark, the MDD and standard deviation for portfolio risk indicators also showed better results. The Sharpe Ratio performed higher than benchmarks and stock market indexes. Through this, we presented the direction of portfolio composition program using machine learning and investor-specific transaction information and showed that it can be used to develop programs for real stock investment. The return is the result of monthly portfolio composition and asset rebalancing to the same proportion. Better outcomes are predicted when forming a monthly portfolio if the system is enforced by rebalancing the suggested stocks continuously without selling and re-buying it. Therefore, real transactions appear to be relevant.