• Bulletin of the Korean Chemical Society
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• 제13권3호
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• pp.315-316
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• 1992

Sodium (3S,4R)-3-[2-(2-aminothiazol-4-yl)-(Z)-2-methoxyi minoacetamido]-4-methoxymethyl-2-azetidinone-1- sulfonate (2) was synthesized in fourteen steps from D-aspartic acid. Starting from D-aspartic acid, (3S,4R)-3-amino-1-t-butyldimethylsilyl-4-methoxym ethyl-2-azetidinone (12) was synthesized in ten steps. Acylation of the amino group of 12 with $2-amino-{\alpha}-(methoxyimino)-4-thiazoleacetic$ acid, desilylation, sulfonation, and ion exchange afforded sodium (3S,4R)-3-[2-(2-aminothiazol-4-yl)-(Z)-2-methoxyi minoacetamido]-4-methoxymethyl-2-azetidinone-1- sulfonate (2). This new ${\beta}-lactam$ compound 2 showed low antibacterial activities.

• 약학회지
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• 제36권6호
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• pp.582-590
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• 1992

S. pneumoniae recP mutant was compared with rec-8 mutant to identify whether they are the same gene or not by determining sensitivity to DNA damaging agents. recP and rec-8 mutant have almost same sensitivity to UV, ethylmethane sulfonate, and methylmethane sulfonate, suggesting that recP has the same function as the rec-8 gene in DNA repair.

• 한국막학회:학술대회논문집
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• 한국막학회 2004년도 춘계 총회 및 학술발표회
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• pp.192-194
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• 2004

FFF에서 외부장은 시료의 종류에 따라 선택적으로 사용되며, 그 외부장의 종류에 따라 세부기술로 구분되어진다. 원심력(gravitational or centrifugal field)을 외부장으로 사용하는 침강장-흐름분획법(sedimentation FFF)은 지름이 0,05∼1um정도인 콜로이드 입자의 분리에 좋은 방법이다. 온도구배(thermal fradient)를 이용하는 열장-흐름분획법(thermal FFF)은 유기 고분자의 분리 및 고분자의 물성연구에 이용된다.(중략)

• Journal of Pharmaceutical Investigation
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• 제21권3호
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• pp.133-141
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• 1991

The fluorescence characteristics of l-anilinonaphthalene-8-sulfonate (ANS) and 2-p-toluidinylnaphthalene-6-sulfonate (TNS) made the dyes useful probes for the determination of the polarity at the binding sites of several water-soluble polyparacyclophanes. Polyparacyclophanes used were 1,6,20,25-tetraaza[ 6.1.6.1]paracyclophane (CPM 44), 1,7,21,27 -tetraaza[7.1.7.1]paracyclophane (CPM 55). 1,7,21,27 -tetraaza-14,34-dioxa[7.1.7.1]paracyclophane (CPE 55) and 1,8,22,29-tetraaza-15,36-dioxa[8.1.8.1] paracyclophane (CPE 66). The fluorescence quantum yield, emission maximum, and half bandwidth of ANS or TNS obtained in a variety of solvent systems were plotted as a function of four kinds of empirical solvent polarity scales such as dielectric constant (D), (D-l)/(2D+1). Y and Z values. It was found that the Z-value-emission maximum $(\overline}V_F,\;cm^{-1})$ profile showed the most reliable linearity. ANS and TNS interacted with CPM 44, CPM 55, CPE 55. CPE 66. ${\alpha}-cyclodextrin$ (CyD) and ${\beta}-CyD$ in the aqueous solution, and from the emission maxima the polarities (Z-value) of their binding sites were calculated to be 92.65, 87.50, 93.35, 84.52, 94.36, and 90.48 for ANS, respectively. and 91.07, 89.68, 85.44, 86.74 and 87.6 for TNS except for ${\alpha}-CyD$, respectively.

• Journal of Pharmaceutical Investigation
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• 제18권3호
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• pp.113-123
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• 1988

A series of water-soluble polyparacyclophanes bearing two diphenylmethane or two diphenyl ether skeletons were investigated to develop useful host compounds by using 1-anilinonaphthalene-6-sulfonate (ANS) and 2-p-toluidinylnaphthalene-6-sulfonate (TNS) as fluorescent hydrophobic substrates in aqueous solution. It was noteworthy that remarkable fluorescent enhancements and blue shifts of ANS and TNS were observed only in the presence of 1,6,20,25-tetraaza[6.1.6.1] paracyclophane (CPM 44) and 1,6,21,27-tetraaza [7.1.7.1] paracyclophane (CPM 55) for diphenylmethane skeleton, and 1,7,21,27-tetraaza-14,34-dioxa [7.1.7.1] paracyclophane (CPE 55) and 1,8,22,29-tetraaza-15,36-dioxa [8.1.8.1] paracyclophane (CPE 66) for diphenyl ether skeleton, comparing with ${\alpha}-\;and\;{\beta}-cyclodextrins$. However, their acyclic analogues such as 4,4'-dimethylaminodiphenylmethane and 4,4'-dimethylaminodiphenyl ether, and paracyclophanes whose cavities were smaller showed only small effects under the same conditions. These facts suggested that hosts and substrates were in an intimate contact which would not occur without larger structures, and thus that guest molecules were strongly incorporated in the hydrophobic cavities of these larger paracyclophanes. The effects of pH on the fluorescent intensity of ANS-CPM 44, ANS-CPM 55, ANS-CPE 55, ANS-CPE 66, TNS-CPM 44, TNS-CPM 55, TNS-CPE 55 and TNS-CPE 66 systems were not significant below pH 2.0, but their fluorescent intensities were markedly reduced with increasing ionic strength.

• Environmental Analysis Health and Toxicology
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• 제7권1_2호
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• pp.67-87
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• 1992

Each detergent-solution in the concentration of 0.4% was prepared with four kinds of raw materials of detergents and two kinds of commercial surfactants for kitchen. LAS (Linear Alkyl Benzene Sulfonate), AOS ($\alpha$-O1effine Sulfonate), SLS (Sodium Lauryl Sulfonate) and SLE (Sodium Lauryl Ester Sulfonate) were used as the raw materials. Vegetables and fruits such as cucumber, crown daisy, lettuce, strawberry and tomatos were diped in each solution and washed 5 times in static or flow state. For the other experiments, tablewares such as porcelain, stainless bowls, glass and plastic cups were diped in each solution and washed also 5 times with cold and hot water in static or flow state. The residues of the detergents on the every steps of wash-conditions were measured. The results of this study were summarized as followings: 1. The residures of the detergents on the tested vegetables and fruits after 5 times washing were detected with the range from 0.450 to 7.120 ppm in static state and from 0.343 to 6.375 ppm in flow state. 2. The residures of the detergents on the tested tablewares after 5 times washing with cold water were observed with the range from 0.057 to 0.815 ppm in static state and from 0.066 to 0.905 ppm in flow state. 4. The residures of the detergents on the tested tablewares after 5 times washing with hot water were determined with the range from 0.061 to 0.424 ppm in static state and from 0.066 to 0.368 ppm in flow state. 4. Independent on detergent types, water temperatures and washing methods, the detergents were remained stablely on the porcelain; 0.057~0.815 ppm, on the stainless bowl; 0.061~0.905 ppm, on the glass cup; 0.0l4~0.592 ppm and on the plastic cup; 0.201~0.592 ppm.

• 한국광학회지
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• 제9권2호
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• pp.76-85
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• 1998

서서히 용액을 증발시키는 늦은 용액증발법을 이용하여 유기단결정 p-toluene sulfonate(PTS) 덩어리와 박막을 제작하였다. 유기 단결정 PTS 덩어리는 Z-scan 방법을 이용하여 1600 nm, 95fs 레이저 광으로 3차와 5차 비선형 굴절률 $n_{2}$와 $n_{3}$를 측정하였으며, PTS 박막 도파관에서는 다중모드 출력을 관측하였다. 입력광의 세기가 2~5 GW/$cm^{2}$영역에서 PTS의 비선형 광학계수는 $n_{2}=6{\times}10^{-4}cm^{2}$/GW, $n_{3}=-7{\times}10^{-5}cm^{4}/GW^{2}$이고 2광자 흡수와 3광자 흡수는 없었다. 빛의 세기가 강한 5~16 GW/$cm^{2}$영역에서는 비선형 슈레딩거식과 빠른 푸리에변환 광전파방법을 이용하여 시료 내에서 전파광의 모양이 가우시안 광에서 왜곡되어 전파되는 것을 전산모의하였다.

• 생명과학회지
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• 제17권5호
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• pp.641-645
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• 2007

염 내성 돌연변이체를 선발하기 위하여, ethyl methane sulfonate(EMS)로 처리된 돌연변이 종자 집단을 사용하였다. 150 mM NaCl 고염 스트레스 하에서 종자 발아 내성을 보이는 세 종류의 EMS 돌연변이체를 선발하였다. 세 종류의 EMS 돌연변이체들 중, salt tolerance 42-14(sto42-14) 돌연변이체는 175 mM NaCl 고농도에서 종자 발아율이 대조구(WT)에 비해 7배 이상의 높은 발아율을 보였다. 또한 내염성 sto42-14 돌연변이체는 glucose(Glc)에 대해서도 비감수성을 갖고 있음을 관찰되었고, 흥미롭게도 sto42-14돌연변이체에 $20{\mu}M$ gibberellin(GA)을 처리한 결과, 대조구에 비해 하배축과 뿌리의 생장이 억제됨을 관찰할 수 있었다. 이러한 결과를 바탕으로, 고염 내성 sto42-14 돌연변이체는 Glc 뿐만 아니라 GA호르몬 반응에도 관련되어져 있음을 알 수 있다.

• 환경위생공학
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• 제8권1호
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• pp.81-91
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• 1993

This paper was carried out to isolate and identify Aeromonas caviae which can degrade Sodium Dodecyl Benzene Sulfonate(SDBS) effectively. And the affecting factors for the ability of bacterial degradation were also studied. Frm October 1991 to February 1992, two hundred samples from sweage in Taegu area and Nakdong river waters in Talsung Gun area were tested. Minimal salt medium which contain SDBS only as a carbon source was used as a culture medium. The isolated new strain was identified as Aeromonas caviae Kim & Kweon. The optimal pH for SDBS degradation were 7.0 and temperature, $32^{\circ}C.$ It was taken 24 hours to degrade SDBS of 20mg/l completely under the optimal pH and temperature. And in the case of 30 mg/l of SDBS, it was taken 36 hours. The nitrogen sources were added to the minimal salt media containing 20mg/l of SDBS, and they were incubated at $32^{\circ}C$ for 14 hours. 86.9% SDBS were degraded after addition of 0.03% peptone as a organic nitrogen source. And 70.5% SDBS after addition of 0.05% ammonium sulfate as a inorganic nitrogen source. In the case of metal compounds(0.015%), the degradation rate for SDBS were 3.5 fold increased in the media containing magnesium chloride and calcium chloride than in the media that were not containing these metal compounds. And where the media containing magnesium chloride was 0.05%, the degradation rate was 65.8%. And above 0.3% NaCI, the degradation rate was decreased slowly.

• 한국응용과학기술학회지
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• 제11권1호
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• pp.71-77
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• 1994

In order to review industrial application of amphoteric surfactants, new types of hydroxy sulfobetaine, 3-(N, N-dimethyl N-dimethyl-N-alkylammonio)-2-hydroxy-1-propane sulfonate and 3-(N, N-dimethyl N-acylammonio)-2-hydroxy-1-propane sulfonate were prepared by the reaction of quaternized sodium 1-chloro-2-hydroxy-3-propane sulfonate with N, N-dimethyl-N-alkylamine and N, N-dimethyl N-acylamido propylamine that have a straight chain radical of 12, 18 carbon atoms respectively in the presence of alkali catalyst. All the reaction products could be separated by means of column and thin layer chromatography, and the yields of all products ranged in $85{\sim}90%$, the structure of them could be confirmed from IR and $^{1}H$-NMR spectra.