• Biotechnology and Bioprocess Engineering:BBE
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• v.8 no.3
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• pp.187-191
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• 2003

Proteolytic enzymes existing in plant cell cultured media are the major reason for the loss of secreted human granulocyte-macrophage colony-stimulating factor (hGM-CSF). The addition of pepstatin, aprotinin and PMSF relatively decreased the proteolytic degradation of hGM-CSF in a conditioned medium, but sufficient prevention against the proteolytic activity could not be obtained with chemical protease inhibitors. Gelatin, as a competitive substrate for protease, showed a stabilizing effect in a conditioned medium. Compared to the initial hGM-CSF concentration in a conditioned medium. with 10 g/L of gelatin, 68% of the hGM-CSF remained after 5 days. In a cell culture experiment, 5 g/L of gelatin significantly stimulated the hGM-CSF production and accumulation in culture media, with no growth inhibition. compared to the controls (4.72 $\mu\textrm{g}$/L), the extracellular hGM-CSF level could be increased to 39.78 $\mu\textrm{g}$/L with the addition of 5 g/L of gelatin.

• Journal of IKEEE
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• v.7 no.2 s.13
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• pp.230-235
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• 2003

A small and integrated MMIC VCO(Voltage Controlled Oscillator) at Ka-band has been developed. This oscillator was designed as Clapp-Gouriet type scheme, fabricated, and implemented on the carrier. This was connected to an alumna substrate on the carrier providing output port for module, utilizing ribbon and wire bonding technique allowing the loss of 0.2dB. This VCO module showed the excellent performance.

• The Journal of Korean Institute of Communications and Information Sciences
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• v.36 no.10A
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• pp.847-851
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• 2011

In this paper, we reported on a high performance MMIC star mixer for millimeter-wave applications. The star mixer was fabricated using drain-source-connected pseudomorphic high electron mobility transistor (PHEMT) diodes considering the PHEMT MMIC full process on 2 mil thick GaAs substrate. The average conversion loss of 13 dB was measured in the RF frequency range of 81 GHz to 86 GHz at LO frequency of 75 GHz with LO power of 10 dBm. The RF-LO isolation characteristics are greater than 30 dB and the input 1-dB compression are approximately 4 dBm. The total chip size is 0.8 mm ${\times}$ 0.8 mm.

• The Journal of Korean Institute of Electromagnetic Engineering and Science
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• v.12 no.1
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• pp.27-36
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• 2001

In this paper, micromachined millimeter-wave cavity resonators ar presented. One-port and two-port cavity resonators at Ka-band are designed using 3D design software, HP $HFSS^{TM}$ ver. 5.5 Cavity resonators are fabricated on Si substrate, which is etched down for the cavity, bonded with a Quartz wafer in which metal patterns for the feeding line coupling slot are formed. One-port resonator shows the resonant frequency of 39.34 GHz, the return loss of 14.5 dB, and the loaded $Q(Q_{L})$ of 150. Two-port cavity resonator shows the resonant frequency of 39 GHz, the insertion and return losses of 4.6dB and 19,9dB, the loaded($Q_{L}$) and unloaded $Q(Q_{U})$) of 44.3 and 107, respectively.

• The Journal of Korean Institute of Electromagnetic Engineering and Science
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• v.11 no.8
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• pp.1313-1321
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• 2000

This paper presents a novel HTS microstrip pseudo-lumped element resonator for the compact and simple filter design. A 7-pole bandpass filter with quasi-elliptic response is designed and fabricated using non-adjacent couplings between resonators. A seven-pole quasi-elliptic filter is fabricated using double sided YBCO on a LaAlO$_3$ substrate with thickness of 0.5 mm and dielectric constant of 23.5. The filter has an insertion loss of 0.8 dB at 20K, a bandwidth of 8 MHz at the center frequency of 1774 MHz, and an attenuation of 33 dB for the cut-off-band of 1 MHz.

• The Journal of Korean Institute of Electromagnetic Engineering and Science
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• v.20 no.3
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• pp.215-221
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• 2009

In this paper, a slotted trapezoidal microstrip fractal patch antenna is designed and fabricated for the vehicle GPS antenna. We designed air substrate patch antenna to obtain gain improvement by the elimination of dielectric loss. By applying fractal structure with crossed slot to trapezoidal patch, we obtained 42.5 % as much patch size as conventional triangular patch antenna. Measured bandwidth was 200 MHz on GPS band under VSWR 2:1 And gain was 4.31 dBi at resonant frequency that is 2$\sim$5 dB higher gain than conventional ceramic patch antenna on GPS band.

• Journal of Environmental Health Sciences
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• v.19 no.3
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• pp.17-21
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• 1993

Characteristics of a downflow anaerobic packed bed reactor with raschig ring ceramics as a packing were measured and discussed for the basic evaluation of the process. A synthesized glucose substrate wastewater were used as a feed and process characteristics such as pH, biogas production, composition of produced gas, COD removal and VSS were measured with the hydraulic retention time (HRT) changing from 0.25 to 2 days. As a result, this type of reactor was applicable in continuous operation within the given HRT range and the transient period approaching the steady state was about 20 days. The content of methane in produced gas increase with HRT was always high above 50% enough to use as energy source. The COD removal efficiency increased gradually as HRT increased. The axial profile of VSS concentration in the reactor usually showed the maximum at the lower region and the minimum at the middle. The VSS concentration at the upper region and the exit appeared similarly. However, at 0.25 day of HRT, the VSS concentration of effluent became higher than that of the upper region. Therefore the optimum HRT of this reactor occurred about 0.5 day, at which the production of methane began to be just stabilized and loss of VSS and COD removal were resonable.

• The Proceeding of the Korean Institute of Electromagnetic Engineering and Science
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• v.24 no.2
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• pp.51-57
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• 2013

The current expanding mobile markets incessantly demands small form factor, low power consumption and high aggregate throughput for silicon-level integration such as memory to logic system. One of emerging solution for meeting this high market demand is 3D through silicon stacking (TSS) technology. Main challenges to bring 3D TSS technology to the volume production level are establishing a cost effective supply chain and building a reliable manufacturing processes. In addition, this technology inherently help increase number of IOs and shorten interconnect length. With those benefits, however, potential signal and power integrity risks are also elevated; increase in PDN inductance, channel loss on substrate, crosstalk and parasitic capacitance. This paper will report recent progress of wide IO memory to high count TSV logic device assembly development work. 28 nm node TSV test vehicles were fabricated by the foundry and assembled. Successful integration of memory wide IO chip with less than a millimeter package thickness form factor was achieved. For this successful integration, we discussed potential signal and power integrity challenges. This report demonstrated functional wide IO memory to 28 nm logic device assembly using 3D package architecture with such a thin form factor.

• Journal of electromagnetic engineering and science
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• v.17 no.2
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• pp.108-110
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• 2017

The global positioning system (GPS) is a useful system in civilian and military applications. However, because of the weak signal, GPS receivers are vulnerable to interference caused by unwanted signals or intentional jammers. To alleviate this issue, a controlled reception pattern antenna (CRPA) array can be employed to adaptively place radiation pattern nulls toward the direction of the signal interference. The performance of the CRPA array improves as the number of antenna elements increases. Therefore, antenna miniaturization is highly desirable for CRPA applications. We designed a compact CRPA array based on seven electrically miniaturized microstrip patch antennas (MPAs) on a 5-inch ground platform. We used a non-Foster matching circuit to match efficiently miniaturized MPAs on an FR-4 substrate. Experimental results show that the non-Foster matching circuit significantly improves such elements of antenna performance as return loss and antenna gain. In addition, we confirmed that the mutual coupling of the proposed CRPA array is less than -45 dB.

• The Journal of the Korea institute of electronic communication sciences
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• v.13 no.4
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• pp.745-750
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• 2018

A Slot array antenna with a phase reversal device is presented for WLAN operation. The array factor and radiation characteristics of the antenna are investigated. For practical application of the radiation pattern, the phase reversal device is used. The antenna is formed on both sides of the substrate ($30mm{\times}96mm{\times}0.2mm$). The measured results show that the proposed antenna has a 10 dB return loss bandwidth of 156 MHz (2.392 - 2.548 GHz) and the measured maximum gain was 8.31 dBi.