• 제목/요약/키워드: Substantial Interest

검색결과 140건 처리시간 0.042초

블록체인 세대별 기술 동향 (Past, Present and Future of Blockchain Technology)

  • 박정숙;박준영;최선미;오진태;김기영
    • 전자통신동향분석
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    • 제33권6호
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    • pp.139-153
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    • 2018
  • The explosive interest in block chain, which was triggered by Bitcoin in 2009, is leading to substantial investment and the development of block chain technology. There is no dispute among experts that block chain will be the next generation of innovation. However, despite the high expectations for block chains, the related technology still has certain limitations. In addition to improving issues such as a low transaction throughput, inefficient agreement algorithms, and an inflexible governance structure, it is necessary to solve various problems for commercialization and full-scale spreading owing to the trilemma problem among the scalability, security, and decentralization. Under this situation, identification of the technology characteristics according to the generation is helpful for the development of the core technology requirements and commercialization blueprint in establishing an R&D direction. Therefore, in this article, the development of blockchain technology is divided into generations and analyzed in terms of the operational structure, consensus algorithm, governance, scalability, and security.

Mitochondria-targeting theranostics

  • Kang, Han Chang
    • 생체재료학회지
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    • 제22권4호
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    • pp.221-234
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    • 2018
  • Background: Interest in subcellular organelle-targeting theranostics is substantially increasing due to the significance of subcellular organelle-targeting drug delivery for maximizing therapeutic effects and minimizing side effects, as well as the significance of theranostics for delivering therapeutics at the correct locations and doses for diseases throughout diagnosis. Among organelles, mitochondria have received substantial attention due to their significant controlling functions in cells. Main body: With the necessity of subcellular organelle-targeting drug delivery and theranostics, examples of mitochondria-targeting moieties and types of mitochondria-targeting theranostics were introduced. In addition, the current studies of mitochondria-targeting theranostic chemicals, chemical conjugates, and nanosystems were summarized. Conclusion: With the current issues of mitochondria-targeting theranostic chemicals, chemical conjugates, and nanosystems, their potentials and alternatives are discussed.

Potential of Endophytic Diaporthe sp. as a New Source of Bioactive Compounds

  • Nagarajan, Kashvintha;Tong, Woei-Yenn;Leong, Chean-Ring;Tan, Wen-Nee
    • Journal of Microbiology and Biotechnology
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    • 제31권4호
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    • pp.493-500
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    • 2021
  • Endophytic fungi are symbiotically related to plants and spend most of their life cycle within them. In nature, they have a crucial role in plant micro-ecosystem. They are harnessed for their bioactive compounds to counter human health problems and diseases. Endophytic Diaporthe sp. is a widely distributed fungal genus that has garnered much interest within the scientific community. A substantial number of secondary metabolites have been detected from Diaporthe sp. inhabited in various plants. As such, this minireview highlights the potential of Diaporthe sp. as a rich source of bioactive compounds by emphasizing on their diverse chemical entities and potent biological properties. The bioactive compounds produced are of significant importance to act as new lead compounds for drug discovery and development.

Evaluation of the MBTI Popularity in South Korea -- An Analysis Based on Media Coverage

  • Wanting Jiang
    • International Journal of Advanced Culture Technology
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    • 제12권1호
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    • pp.26-33
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    • 2024
  • With the start of COVID-19 in 2020, the MBTI test became popular among Korean young generation and then developed into a nationwide hot topic. This paper aims to investigate the characteristics of the MBTI popularity in Korea and the public opinions toward this phenomenon. With the analysis of the reports contents, 231 news reports related to MBTI were selected from KINDS (Korea Integrated News Database System) as research samples. The general attitude of the media towards MBTI tests and the reasons for the formation of positive and negative evaluations will be discussed from three perspectives: media attention, media attitudes and cognitive sources. The research finds that the increasing interest in MBTI among the younger generation in Korea is driven by a post-epidemic desire for self-exploration, emotional planning, and online group affiliation. MBTI has gained quasi-scientific status, similar to horoscopes, influenced by celebrities and a substantial fan base in online communication. While widely used for entertainment and social currency, there are concerns that extensive labeling may unconsciously impact individuals' self-perception and hinder the development of a holistic and objective cognitive framework.

인플레와 M2 유통속도(流通速度) (M2 Velocity and Expected Inflation in Korea: Implications for Interest Rate Policy)

  • 박우규
    • KDI Journal of Economic Policy
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    • 제13권2호
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    • pp.3-19
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    • 1991
  • 인플레기대심리(期待心理)의 지속으로 통화량규제(通貨量規制)의 중요성이 부각되는 가운데 투자금융회사의 업종전환(業種轉換), 금리자유화추진(金利自由化推進) 등으로 각종 통화지표(通貨指標)의 움직임이 불안정해질 우려 때문에 통화정책운용(通貨政策運用)에 어려움을 주고 있다. 그러나 본고(本稿)의 연구결과(硏究結果)에 의하면 70년대 중반 이후 금융환경(金融環境)이 급변하여 왔음에도 불구하고 실질(實質)M2는 실질(實質)GNP 및 기회비용(機會費用)(예상(豫想)인플레율(率)에서 M2가중평균수신금리(加重平均受信金利)를 뺀 것)과 장기적으로 안정적인 관계를 가지며, 이는 유통속도(流通速度)와 기회비용간(機會費用間)의 정(正)의 장기적 균형관계로 간략화 시킬 수 있는 것으로 나타났다. 따라서 사안(事案)의 성격에 따라서 다르겠으나 앞으로의 금융구조변화(金融構造變化)가 반드시 M2유통속도(流通速度)의 움직임을 불안정하게 할 것으로 미리 단정할 필요는 없겠다. 또한 예상(豫想)인플레율(率)이 M2가중평균수신금리(加重平均受信金利)를 지속적으로 상회한다면 유통속도(流通速度)도 그 간의 하락추세에서 벗어나 궁극적으로 상승하게 되며, 이는 기존의 금융정책기조(金融政策基調)의 변화를 요구하는 것이다. 즉 금리자유화(金利自由化)가 이루어져 있지 않은 현여건(現與件) 하에서나 혹은 향후(向後)에 일부(一部) 금리(金利)만을 자유화할 경우에는 정책당국이 시장기능(市場機能)을 대신하여 예상(豫想)인플레율(率)의 변화를 감안하여 수신금리(受信金利)를 수시로 조정하여야 한다. 또한 실물적(實物的) 요인(要因)이 아닌 금융산업개편(金融産業改編)과 같은 금융적(金融的) 요인(要因)에 의한 통화증가가능성(通貨增加可能性)이 존재한다면 수신금리(受信金利)를 탄력적(彈力的)으로 상향조정함으로써 실물경제(實物經濟)에 대한 충격을 최소화하는 등 금리정책(金利政策)의 중요성을 제고하여야 한다.

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스퍼터링 방법으로 성장시킨 나노구조의 Ga 농도 변화에 따른 형상 변화

  • 김영이;우창호;조형균
    • 한국재료학회:학술대회논문집
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    • 한국재료학회 2009년도 추계학술발표대회
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    • pp.23.1-23.1
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    • 2009
  • ZnO is of great interest for various technological applications ranging from optoelectronics to chemical sensors because of its superior emission, electronic, and chemical properties. In addition, vertically well-aligned ZnO nanorods on large areas with good optical and structural properties are of special interest for the fabrication of electronic and optical nanodevices. To date, several approaches have been proposed for the growth of one-dimensional (1D) ZnO nanostructunres. Several groups have been reported the MOCVD growth of ZnO nanorods with no metal catalysts at $400^{\circ}C$, and fabricated a well-aligned ZnO nanorod array on a PLD prepared ZnO film by using a catalyst-free method. It has been suggested that the synthesis of ZnO nanowires using a template-less/surfactant-free aqueous method. However, despite being a well-established and cost-effective method of thin film deposition, the use of magnetrons puttering to grow ZnO nanorods has not been reported yet. Additionally,magnetron sputtering has the dvantage of producing highly oriented ZnO film sat a relatively low process temperature. Currently, more effort has been concentrated on the synthesis of 1D ZnO nanostructures doped with various metal elements (Al, In, Ga, etc.) to obtain nanostructures with high quality,improved emission properties, and high conductance in functional oxide semiconductors. Among these dopants, Ga-doped ZnO has demonstrated substantial advantages over Al-doped ZnO, including greater resistant to oxidation. Since the covalent bond length of Ga-O ($1.92\;{\AA}$) is nearly equal to that of Zn-O ($1.97\;{\AA}$), high electron mobility and low electrical resistivity are also expected in the Ga-doped ZnO. In this article, we report the successful growth of Ga-doped ZnO nanorods on c-Sapphire substrate without metal catalysts by magnetrons puttering and our investigations of their structural, optical, and field emission properties.

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우리나라 일부지역 연령대별 건강기능식품 이용 실태 (Consumption of Health Functional Foods according to Age Group in Some Regions of Korea)

  • 정혜경;이해영
    • 대한영양사협회학술지
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    • 제17권2호
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    • pp.190-205
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    • 2011
  • The purpose of this study was to investigate the consumption of health functional foods according to age group. We surveyed 300 subjects with quota sampling aged 10 to 50 and over. The rate of consumption of health functional foods by users was substantial (52.7%). Consumers of health functional foods showed higher scores for interest in health (3.97 vs 3.49, P<0.001) and knowledge of health functional foods (3.79 vs 3.30, P<0.001) than non-consumers of health functional foods. Regarding consumers of health functional foods, the number (P<0.01) and types (P<0.05) of health functional foods, reasons for taking (P<0.05), motivations for buying (P<0.05), periods of taking (P<0.001), cost per month (P<0.01), observance of instruction (P<0.01), and effectiveness (P<0.01) were significantly different according to age group. For non-consumers of health functional foods, reasons for not-taking (P<0.01) and types of health functional foods to be planned (P<0.001) were different according to age group. For consumers and non-consumers, problems (P<0.01) andimprovements (P<0.001) for health functional foods showed significant differences according to age group. The majority of subjects (85.4%) answered that heath functional foods had no side-effects. Reported side effects were inappetence (6.6%), constipation (2.6%), and headache (2.0%). In conclusion, differentiated strategies and specialized education programs according to age group might be needed for promoting adequate consumption and preventing side-effects of health functional foods.

동적 시준을 이용한 CT 촬영과 볼록한 관심영역의 영상재구성 (Dynamically Collimated CT Scan and Image Reconstruction of Convex Region-of-Interest)

  • 진승오;권오경
    • 대한의용생체공학회:의공학회지
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    • 제35권5호
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    • pp.151-159
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    • 2014
  • Computed tomography (CT) is one of the most widely used medical imaging modality. However, substantial x-ray dose exposed to the human subject during the CT scan is a great concern. Region-of-interest (ROI) CT is considered to be a possible solution for its potential to reduce the x-ray dose to the human subject. In most of ROI-CT scans, the ROI is set to a circular shape whose diameter is often considerably smaller than the full field-of-view (FOV). However, an arbitrarily shaped ROI is very desirable to reduce the x-ray dose more than the circularly shaped ROI can do. We propose a new method to make a non-circular convex-shaped ROI along with the image reconstruction method. To make a ROI with an arbitrary convex shape, dynamic collimations are necessary to minimize the x-ray dose at each angle of view. In addition to the dynamic collimation, we get the ROI projection data with slightly lower sampling rate in the view direction to further reduce the x-ray dose. We reconstruct images from the ROI projection data in the compressed sensing (CS) framework assisted by the exterior projection data acquired from the pilot scan to set the ROI. To validate the proposed method, we used the experimental micro-CT projection data after truncating them to simulate the dynamic collimation. The reconstructed ROI images showed little errors as compared to the images reconstructed from the full-FOV scan data as well as little artifacts inside the ROI. We expect the proposed method can significantly reduce the x-ray dose in CT scans if the dynamic collimation is realized in real CT machines.

Financial and Economic Risk Prevention and Countermeasures Based on Big Data and Internet of Things

  • Songyan Liu;Pengfei Liu;Hecheng Wang
    • Journal of Information Processing Systems
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    • 제20권3호
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    • pp.391-398
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    • 2024
  • Given the further promotion of economic globalization, China's financial market has also expanded. However, at present, this market faces substantial risks. The main financial and economic risks in China are in the areas of policy, credit, exchange rates, accounting, and interest rates. The current status of China's financial market is as follows: insufficient attention from upper management; insufficient innovation in the development of the financial economy; and lack of a sound financial and economic risk protection system. To further understand the current situation of China's financial market, we conducted a questionnaire survey on the financial market and reached the following conclusions. A comprehensive enterprise questionnaire from the government's perspective, the enterprise's perspective and the individual's perspective showed that the following problems exist in the financial and economic risk prevention aspects of big data and Internet of Things in China. The political system at the country's grassroots level is not comprehensive enough. The legal regulatory system is not comprehensive enough, leading to serious incidents of loan fraud. The top management of enterprises does not pay enough attention to financial risk prevention. Therefore, we constructed a financial and economic risk prevention model based on big data and Internet of Things that has effective preventive capabilities for both enterprises and individuals. The concept reflected in the model is to obtain data through Internet of Things, use big data for screening, and then pass these data to the big data analysis system at the grassroots level for analysis. The data initially screened as big data are analyzed in depth, and we obtain the original data that can be used to make decisions. Finally, we put forward the corresponding opinions, and their main contents represent the following points: the key is to build a sound national financial and economic risk prevention and assessment system, the guarantee is to strengthen the supervision of national financial risks, and the purpose is to promote the marketization of financial interest rates.

(-)-Epigallocatechin-3-Gallate Induces Apoptosis and Inhibits Invasion and Migration of Human Cervical Cancer Cells

  • Sharma, Chhavi;Nusri, Qurrat El-Ain;Begum, Salema;Javed, Elham;Rizvi, Tahir A.;Hussain, Arif
    • Asian Pacific Journal of Cancer Prevention
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    • 제13권9호
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    • pp.4815-4822
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    • 2012
  • Invasion and metastasis are the major causes of cancer-related death. Pharmacological or therapeutic interventions such as chemoprevention of the progression stages of neoplastic development could result in substantial reduction in the incidence of cancer mortality. (-)-Epigallocatechin-3-gallate (EGCG), a promising chemopreventive agent, has attracted extensive interest for cancer therapy utilizing its antioxidant, anti-proliferative and inhibitory effects on angiogenesis and tumor cell invasion. In this study, we assessed the influence of EGCG on the proliferative potential of HeLa cells by cell viability assay and authenticated the results by nuclear morphological examination, DNA laddering assay and cell cycle analysis. Further we analyzed the anti-invasive properties of EGCG by wound migration assay and gene expression of MMP-9 and TIMP-1 in HeLa cells. Our results indicated that EGCG induced growth inhibition of HeLa cells in a dose- and time-dependent manner. It was observed that cell death mediated by EGCG was through apoptosis. Interestingly, EGCG effectively inhibited invasion and migration of HeLa cells and modulated the expression of related genes (MMP-9 and TIMP-1). These results indicate that EGCG may effectively suppress promotion and progression stages of cervical cancer development.