• 제목/요약/키워드: Substance Use

검색결과 460건 처리시간 0.031초

근로자의 화학물질 노출관련 기록 보존에 관한 연구 (Record Keeping of Employee Exposure to Chemical Hazards under Industrial Safety and Health Law)

  • 오상민;박동욱;유성재;정진우;임경택;이재환;하권철
    • 한국산업보건학회지
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    • 제23권4호
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    • pp.367-373
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    • 2013
  • Objectives: Employee exposure record refers to a record containing information about environmental (workplace) monitoring or measuring of a toxic substance or harmful physical agent. The aims of this study were to examine problems related to exposure records and provide some amendments to the Korean Industrial Safety & Health Act for the effective management of chemical substances under the law. Methods: This study performed a literature search and review on legal provisions related to exposure records of a number of different countries, including Korea, the USA, Japan, EU, Germany, and the UK. They were compared and investigated and the amendment of articles was suggested. Results: The results of this study were provided as suggested amendments to the related act. There were a variety of ways of improvement, including a 30-year retention period and the introduction of new access methods, contents, transfer, and maintenance methods. All exposure data elements have to be standardized, including reference to a similar exposure group (SEG), sampling strategy, and circumstances of exposure (e.g., date, shift length, use of personal protective equipment, etc.). The SEGs are described by process, job, task, and environmental agent. Conclusions: This study is expected to provide for the amendment of the related act in order to ensure effective management of exposure records and is helpful for solving the cause and result of occupational disease by keeping exposure records according to the Industrial Safety & Health Act.

Remediation of heavy metal-contaminated soils using eco-friendly nano-scale chelators

  • Lim, Heejun;Park, Sungyoon;Yang, Jun Won;Cho, Wooyoun;Lim, Yejee;Park, Young Goo;Kwon, Dohyeong;Kim, Han S.
    • Membrane and Water Treatment
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    • 제9권3호
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    • pp.137-146
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    • 2018
  • Soil washing is one of the most frequently used remediation technologies for heavy metal-contaminated soils. Inorganic and organic acids and chelating agents that can enhance the removal of heavy metals from contaminated soils have been employed as soil washing agents. However, the toxicity, low removal efficiency and high cost of these chemicals limit their use. Given that humic substance (HS) can effectively chelate heavy metals, the development of an eco-friendly, performance-efficient and cost-effective soil washing agent using a nano-scale chelator composed of HS was examined in this study. Copper (Cu) and lead (Pb) were selected as target heavy metals. In soil washing experiments, HS concentration, pH, soil:washing solution ratio and extraction time were evaluated with regard to washing efficiency and the chelation effect. The highest removal rates by soil washing (69% for Cu and 56% for Pb) were achieved at an HS concentration of 1,000 mg/L and soil:washing solution ratio of 1:25. Washing with HS was found to be effective when the pH value was higher than 8, which can be attributed to the increased chelation effect between HS and heavy metals at the high pH range. In contrast, the washing efficiency decreased markedly in the low pH range due to HS precipitation. The chelation capacities for Cu and Pb in the aqueous phase were determined to be 0.547mmol-Cu/g-HS and 0.192mmol-Pb/g-HS, respectively.

압전방식 초음파 치석제거기의 작업조건에 따른 치과주조용 합금의 삭제에 관한 연구 (The effect of working parameters on removal of casting gold alloy using a piezoelectric ultrasonic scaler with scaler tip in vitro)

  • 차국봉;김원경;이영규;김영성
    • Journal of Periodontal and Implant Science
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    • 제39권2호
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    • pp.139-148
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    • 2009
  • Purpose: Ultrasonic scalers have been widely used for removing biofilm which is considered as major etiologic factor of periodontal disease. The purpose of this study was to evaluate the effect of working parameters of piezoeletric ultrasonic scaler with scaler tip (No. 1 tip) on casting gold alloy removal. Methods: Type III dental casting gold alloy (Firmilay$^{circledR}$, Jelenko Inc, CA, USA) was used as substitute for tooth substance. Piezoeletric ultrasonic scaler and No.1 scaler tip (P-Max$^{circledR}$, Satelec, France) were selected. The selected working parameters were mode (P mode, S mode), power setting (2, 4, 8) and lateral force (0.5 N, 1.0 N, 2.0 N). The effect of working parameters was evaluated in terms of ablation depth, ablation width and ablation area. Results: Mode influenced ablation depth and ablation area. Power also influenced ablation depth and ablation area. Especially, Power 2 and power 8 showed statistically significant difference. Lateral force had influence on ablation width, and 0.5 N resulted significant increase compared with 1.0 N and 2.0 N. Ablation depth was influenced by mode, power and lateral force and defect width was influenced by lateral force. Ablation area was influenced by mode and power. Conclusions: It can be concluded that the use of piezoelectric ultrasonic scaler with No. 1 scaler tip in S mode and high power may result in significant loss of tooth substance.

습식 세정법에서 암모니아 대체물질에 관한 연구 (Studies on the aqueous ammonia alternatives in the wet scrubbing method)

  • 김재강;이주열;박병현;최진식
    • 한국응용과학기술학회지
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    • 제33권1호
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    • pp.110-117
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    • 2016
  • 기존 연구에서는 스크러버를 이용한 $NO_2$ 를 제거하기 위해 암모니아 수용액을 적용한다. 하지만 암모니아는 독성 및 악취가 강해 실선 적용에 어려움이 따를 수 있어, 암모니아를 대체할 수 있는 물질을 찾기 위해 이 연구를 진행하였다. 대체 물질로는 수산화나트륨(NaOH), 티오황산나트륨($Na_2S_2O_3$), 요소(Urea)를 사용하였다. 세정액을 제외한 모든 부분은 기존 암모니아를 적용한 실험의 최적 조건과 동일하게 진행하였다. 그 결과 실험에 사용된 세 가지 물질 중 두 물질은 암모니아 용액과 대체가 가능한 것으로 사료되었으며, 최적조건은 각각 NaOH 2.5 %, $Na_2S_2O_3$ 5.0 % 에서 가장 높은 효율을 나타냈다. Urea는 효율이 일정하게 지속되지 않아 대체 물질로는 적합하지 않음을 확인 할 수 있었다.

The Effect of Dimethyl Dimethoxy Biphenyl Dicarboxylate (DDB) against Tamoxifen-induced Liver Injury in Rats: DDB Use Is Curative or Protective

  • El-Beshbishy, Hesham A.
    • BMB Reports
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    • 제38권3호
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    • pp.300-306
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    • 2005
  • Tamoxifen citrate is an anti-estrogenic drug used for the treatment of breast cancer. It showed a degree of hepatic carcinogenesis, when it used for long term as it can decrease the hexose monophosphate shunt and thereby increasing the incidence of oxidative stress in liver rat cells leading to liver injury. In this study, a model of liver injury in female rats was done by intraperitoneal injection of tamoxifen in a dose of 45 mg/kg body weight for 7 successive days. This model produced a state of oxidative stress accompanied with liver injury as noticed by significant declines in the antioxidant enzymes (glutathione-S-transferase, glutathione peroxidase and catalase) and reduced glutathione concomitant with significant elevations in TBARS (thiobarbituric acid reactive substance) and liver transaminases; sGPT (serum glutamate pyruvate transaminase) and sGOT (serum glutamate oxaloacetate transaminase) levels. The oral administration of dimethyl dimethoxy biphenyl dicarboxylate (DDB) in a dose of 200 mg/kg body weight daily for 10 successive days, resulted in alleviation of the oxidative stress status of tamoxifen-intoxicated liver injury in rats as observed by significant increments in the antioxidant enzymes (glutathione-S-transferase, glutathione peroxidase and catalase) and reduced glutathione concomitant with significant decrements in TBARS and liver transaminases; sGPT and sGOT levels. The administration of DDB before tamoxifen intoxication (as protection) is more little effective than its curative effect against tamoxifen-induced liver injury. The data obtained from this study speculated that DDB can mediate its biochemical effects through the enhancement of the antioxidant enzyme activities and reduced glutathione level as well as decreasing lipid peroxides.

Photo-Ames Assay를 이용한 광발암성 예측 (Prediction of Photo-Carcinogenicity from Photo-Ames Assay)

  • Hong Mi Young;Kim Ji Young;Chung Moon Koo;Lee Michael
    • 한국환경성돌연변이발암원학회지
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    • 제25권1호
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    • pp.6-12
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    • 2005
  • Many compounds might become activated after absorption of UV light energy. In some cases, the resulting molecule may undergo further biological reaction of toxicological relevance related especially to the photo-carcinogenicity resulting from photo-genotoxicity. However, no regulatory requirements have been issued with the exception of guideline issued by the Scientific Committee of Cosmetology, Commission of the European Communities (SCC/EEC) on the testing of sunscreens for their photo-genotoxicity. Thus, the objectives of this study are to investigate the utility of photo-Ames assay for detecting photo-mutagens, and to evaluate its ability to predict rodent photo-carcinogenicity. Photo-Ames assay was performed on five test substances that demonstrated positive results in photo-carcinogenicity tests: 8-methoxypsoralen (photoactive substance that forms DNA adducts in the presence of ultraviolet A irradiation), chlorpromazine (an aliphatic phenothiazine an a-adr-energic blocking agent), lomefloxacin (an antibiotic in a class of drugs called fluoroquinolones), anthracene (a tricyclic aromatic hydrocarbon a basic substance for production of anthraquinone, dyes, pigments, insecticides, wood preservatives and coating materials) and retinoic acid (a retinoid compound closely related to vitamin A). Out of 5 test substances, 3 showed a positive outcome in photo-Ames assay. With this limited data set, an investigation into the predictive value of this photo-Ames test for determining the photo-carcinogenicity showed that photo-Ames assay has relatively low sensitivity (the ability of a test to predict carcinogenicity). Thus, to determine the use of in vitro genotoxicity tests for prediction of carcinogenicity,' several standard photo-genotoxicity assays should be compared for their suitability in detecting photo-genotoxic compounds.

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대화형 방송 환경에서 부가서비스 제공을 위한 객체 추적 시스템 (Object Tracking System for Additional Service Providing under Interactive Broadcasting Environment)

  • 안준한;변혜란
    • 한국정보과학회논문지:정보통신
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    • 제29권1호
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    • pp.97-107
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    • 2002
  • 본 논문은 대화형 방송환경에서 부가서비스를 제공받기 위해서 탐다운(Top-Down)메뉴 검색을 하는 것이 아니라, 방송영상의 화면 내부에서 부가서비스가 제공되길 원하는 객체를 선택했을 때 선택한 객체에 대한 부가서비스를 제공하는 새로운 방법을 제안한다. 이를 위해서는 실시간으로 방송되고 있는 동영상과 객체정보(위치, 크기, 모양)의 동기를 맞추는 기술과 동영상 내부의 객체 추적 기술이 필수적이다. 동영상과 객체정보의 동기를 맞추는 기술은 마이크로소프트사의 다이렉트쇼(DirectShow)를 이용하였으며, 객체를 추적하기 위한 방법은 객체를 크게 사람과 사물로 나누어, 사람의 얼굴은 모델을 만들어 추적하는 모델 기반 얼굴 추적 방법(Model-based face tracking)을 사용하고 나머지 사물에 대해서는 객체의 영역을 지정하여 영역을 추적하는 움직임 기반 추적 방법(Motion-based Tracking)을 적용하였다. 또한 움직임 기반 추적을 할 수 있도록 하고 모델 기반 추적 방법을 적용하여 움직임이 큰 객체도 검색 영역 확장 없이 정확한 추적을 할 수 있도록 하고 모델 기반 추적 방법에는 타원 모델과 색상 모델을 결합한 얼굴 모델을 적용하여 얼굴이 회전하여도 정확한 추적을 할 수 있도록 개선하였다.

모형레진 근관에서 엔진 구동용 니켈-타이타늄 파일의 경사도의 차이에 따른 근관성형력의 비교 (COMPARISON OF SHAPING ABILITY OF NICKEL-TITANIUM ROTARY FILES WITH DIFFERENT TAPER IN SIMULATED RESIN CANALS)

  • 금기연;임경란;정일영;이승종;이찬영
    • Restorative Dentistry and Endodontics
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    • 제25권1호
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    • pp.78-84
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    • 2000
  • The aim of this study was to compare shaping ability of nickel-titanium rotary files with different taper in simulated resin canals. The instruments used in this study were GT with .04 taper ProFile with ISO-sized tip, .04 taper ProFile with ISO-sized tip alone, and .02 taper Naviflex file and all canals were prepared by crown-down technique. A total of 30 composite images were made from pre- and post-canal scanned images using Scanjet 4C scanner and Corel photopaint 8.0 and then, prevalence of canal aberrations was measured. The amount of coronal substance the instruments removed was also calculated two-dimensionally on digitized images with the Brain C software to compare the relative enlarging efficiency. Finally, the prepared internal canal form was evaluated three-dimensionally with impression technique. The results were as follows; 1. The incidence of zipping in Naviflex group was significantly high compared to the other two groups(P<.05). 2. The amount of coronal substance the GT combined group removed was significantly larger than the other two groups(P<.05). 3. The GT combined group produced canals with good taper and flow. Under the conditionas of this study, the combined use of larger tapered nickel-titanium rotary files prepared simulated canals safely, efficiently and with good three-dimensional form.

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미국 환경법의 Imminent & Substantial Endangerment에 대한 이해 및 사례별 분석 (Understanding Imminent & Substantial Endangerment (ISE) in the U.S. Environmental Laws and Analysis on ISE Uses)

  • 정승우
    • 한국지하수토양환경학회지:지하수토양환경
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    • 제14권3호
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    • pp.14-21
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    • 2009
  • 미국 환경법에 규정된 Imminent & Substantial Endangerment(ISE) 조항에 대한 정의, 결정 및 적용사례를 분석하였다. ISE는 행정권자가 현재의 환경오염상황이 인체에 급박하고 실질적인 위해를 가할 수 있는 오염으로 판단할 경우 오염책임자에게 대책을 강구하게 하는 환경오염 상황 및 환경법상의 조항으로 정의된다. 이때의 행정권자의 대책 요구는 권고, 행정명령, 민사소송, 형사소송 등 다양하게 이루어지며 모든 행정 집행 과정에 ISE가 언급된다. ISE의 판단을 위해서는 1) a possible ISE 2) because of actual or threatened release 3) of a hazardous substance 4) from a facility, 네 가지 요소에 대한 명확한 증거가 있어야 한다. 그러나 네 가지 요소에 대한 정의는 매우 광범위하며 유연성을 가지고 있어, ISE 판단은 행정권자의 충분한 자료 확보와 주관적인 판단에 따르는 것으로 나타났다. 또한 ISE 판단은 판단 주체에 따라 차이를 보이지만 공통적인 사항은 매우 상세한 현장조사 결과 및 과학적인 정황에 기인하고 있다. 미국내 ISE 행정명령에 대한 기본 문서 형태 및 내용은 규정되어 있지만 ISE 판단에 대한 구체적인 정량적 기준 및 방법은 정의되어 있지 않았다.

미세조류 분리/회수를 위한 세포외 고분자물질 생물 응집제 활용 (Application of extracellular polymeric substances (EPSs)-bioflocculant for recovery of microalgae)

  • 최오경;;김종락;맹승규;김극태;이재우
    • 상하수도학회지
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    • 제35권1호
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    • pp.63-69
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    • 2021
  • Microalgae are primary producers of aquatic ecosystems, securing biodiversity and health of the ecosystem and contributing to reducing the impact of climate change through carbon dioxide fixation. Also, they are useful biomass that can be used as biological resources for producing valuable industrial products. However, harvesting process, which is the separation of microalgal biomass from mixed liquor, is an important bottleneck in use of valorization of microalgae as a bioresource accounting for 20 to 30% of the total production cost. This study investigates the applicability of sewage sludge-derived extracellular polymeric substance (EPS) as bioflucculant for harvesting microalgae. We compared the flocculation characteristics of microalgae using EPSs extracted from sewage sludge by three methods. The flocculation efficiency of microalgae is closely related to the carbohydrate and protein concentrations of EPS. Heat-extracted EPS contains the highest carbohydrate and protein concentrations and can be a best-suited bioflocculant for microalgae recovery with 87.2% flocculation efficiency. Injection of bioflocculant improved the flocculation efficiency of all three different algal strains, Chlorella Vulgaris, Chlamydomonas Asymmetrica, Scenedesmus sp., however the improvement was more significant when it was used for flocculation of Chlamydomonas Asymmetrica with flagella.