• Proceedings of the PSK Conference
• /
• 2002.10a
• /
• pp.254.1-254.1
• /
• 2002

The effects of aporplline isoquinoline alkaloids such as liriodenine. anonaine and asimilobine on dopamine biosynthesis in PC12 cells were investigated. Treatment of PC12 cells with liriodenine (10 ${\mu}$M), anonaine (0.05 ${\mu}$M) and asimilobine (0.15 ${\mu}$M) showed 33.6%, 37.7% and 35.1 % inhibition of dopamine content for 12 h. The IC$\sub$50/ values of liriodenine. anonaine and asimilobine were 8.4 ${\mu}$M. 0.05 ${\mu}$M and 0.13 ${\mu}$M. respectively. (omitted)

• Molecules and Cells
• /
• v.43 no.2
• /
• pp.182-187
• /
• 2020

When cells are stimulated by growth factors, they make a critical choice in early G₁ phase: proceed forward to S phase, remain in G₁, or revert to G₀ phase. Once the critical decision is made, cells execute a fixed program independently of extracellular signals. The specific stage at which the critical decision is made is called the restriction point or R-point. The existence of the R-point raises a major question: what is the nature of the molecular machinery that decides whether or not a cell in G₁ will continue to advance through the cell cycle or exit from the cell cycle? The R-point program is perturbed in nearly all cancer cells. Therefore, exploring the nature of the R-point decision-making machinery will provide insight into how cells consult extracellular signals and intracellular status to make an appropriate R-point decision, as well into the development of cancers. Recent studies have shown that expression of a number of immediate early genes is associated with the R-point decision, and that the decision-making program constitutes an oncogene surveillance mechanism. In this review, we briefly summarize recent findings regarding the mechanisms underlying the context-dependent R-point decision.

• Applied Chemistry for Engineering
• /
• v.10 no.1
• /
• pp.73-79
• /
• 1999

The superstructured $Li_{4/3}Ti_{5/3}O_4$ was prepared by sol-gel process using a mixed solution of lithium acetate (LA) and titanium n-butoxide (TNB). The gel phase was obtained by adding ammonia water ($NH_4OH/TNB$ mole ratio of 0.35) and water ($H_2O/TNH$ mole ratio of 3.5) into the clear sol that was prepared after mixing TNB/LA mole ratio of 5/4 with AA/TNB mole raio of 0.125. It was found that the most suitable $Li_{4/3}Ti_{5/3}O_4$ was obtained by heat treatment of xerogel at $600^{\circ}C$ for 30 hrs. The synthesized $Li_{4/3}Ti_{5/3}O_4$ showed an initial discharge capacity of 174 mAh/g and the capacity loss of about 27.3% during 25 cycles in Li/1M $LiClO_4(in\;PC)/Li_{4/3}Ti_{5/3}O_4$ at current density of $0.15mA/cm^2$ and the voltage range of 0.5~3.0 V.

• Journal of the Korean Institute of Electrical and Electronic Material Engineers
• /
• v.20 no.1
• /
• pp.25-30
• /
• 2007

In this paper, lead-free [$Li_{0.04}(Na_{y}K_{1-y})_{0.96}](Nb_{0.86}Ta_{0.1}Sb_{0.04})O_{3}$ (y=0.4 - 0.58) ceramics were manufactured using conventional miked oxide method for acoustic emission(AE) sensor application and their dielectric and piezoelectric properties were investigated with the variations of Na/K ratio. The samples in the composition Na/K=54/46 exhibited excellent electrical properties of $d_{33}=300$ PC/N and kp=0.49. Taking into consideration above piezoelectric properties, it can be concluded that the [$Li_{0.04}(Na_{y}K_{1-y})_{0.96}](Nb_{0.86}Ta_{0.1}Sb_{0.04})O_{3}$ system ceramics are the promising lead-free materials capable of substituting PZT system ceramics.

• Transactions on Electrical and Electronic Materials
• /
• v.3 no.2
• /
• pp.28-31
• /
• 2002

The Cdl-xZnxTe film was fabricated by thermal evaporation for the flat-panel X-ray detector. The stoichimetric ratio and the crystal structure of a polycrystalline Cd$_{1-x}$ Zn$_{x}$Te were investigated by EPMA and XRD, respectively. The leakage current and X-ray sensitivity of the fabricated films were measured to analyze the X-ray response characteristic of Zn in the polycrystalline CdZnTe thin film. The leakage current and the output charge density of Cd$_{0.7}$Zn$_{0.3}$Te thin film were measured to 0.37 nA/cm$^2$ and 260 pc/cm$^2$ at an applied voltage of 2.5 V/${\mu}{\textrm}{m}$, respectively. Experimental results showed that the increase of Zn doping rates in Cd$_{1-x}$ Zn$_{x}$Te detectors reduced the leakage current and improved the signal to noise ratio significantly.

• Proceedings of the Korean Geotechical Society Conference
• /
• 1999.11b
• /
• pp.3-11
• /
• 1999

It has been said from previous studies that the preconsolidation pressure (p$\sub$c/)of Nangton Rive. deposit is considerably less than the in situ effective burden pressure (p'$\sub$$\upsilon$ο/). Question has risen whether this small pc vale is due to under consolidation or unsuitable laboratory test including low small quality. As a cooperative research program between PHRI (Port and Harbor Research Institute) and Pusan National University, an extensive soil investigation was carried out at a site of Yangsan, Pusan, using the Japanese sampler. It Is found that although p$\sub$c/ value at the site is slightly greater than p'$\sub$$\upsilon$ο/, its over consolidation ratio (OCR) is quite small compared with aged normally consolidated clay in Japan.

• Proceedings of the Korean Institute of Electrical and Electronic Material Engineers Conference
• /
• 2000.11a
• /
• pp.359-362
• /
• 2000

The purpose of this study is to research and develop graphene composite for lithium polymer battery. VO(graphene) composite is one of the promising material as a electrode active material for lithium polymer battery(LPB). We investigated AC impedance response and charge/discharge cycling of VO(graphene)/SPE/Li cells. The first discharge capacity of VO(graphene) cathode with 50wt.% V$_2$O$\sub$5/ was 150mAh/g, while that of VO(graphene) cathode with 85wt.% V$_2$O$\sub$5/ was 248mAh/g. The Ah efficiency was above 98% after the 2nd cycle. The discharge capacity of VO(graphene) anode with 3wt.% V$_2$O$\sub$5/ was 718 and 266mAh/g at cycle 1 and 10 at room temperature, respectively. The VO(graphene) anode with 3wt.% V$_2$O$\sub$5/ in PVDF-PAN-PC-EC-LiC1O$_4$ electrolyte showed good capacity with cycling.

• Journal of the Korean Geotechnical Society
• /
• v.35 no.12
• /
• pp.91-100
• /
• 2019

Hollow prestressed concrete-filled steel tube (HCFT) piles, which combines PHC piles inside thin-wall steel tubes, were developed to increase the flexural strength of the pile with respect to the lateral load. Since P-M curves are needed for evaluating the structural safety of piles when applying HCFT piles to fields, equations for plotting P-M curves of HCFT piles in limit states were proposed. When the yield strength is applied to the steel tube and PC steel bar of HCFT piles, the proposed equations significantly underestimated the flexural strength of HCFT piles. Unlike the flexural strength test results, the proposed equations also provide greater flexural strengths for 12 mm thick steel pipe piles with the same diameter than for HCFT piles. However, when the ultimate strengths are used instead of the yield strengths for the steel tube and PC steel bar, the proposed equations provide the flexural strengths very close to the flexural strength test results.

• Korean Journal of Fisheries and Aquatic Sciences
• /
• v.53 no.2
• /
• pp.147-155
• /
• 2020

This study aimed amount optimization of salmon Oncorhynchus keta mince (SM), threadfin bream Nemipterus virgatus surimi (TBS), natural tomato (NTC) and paprika colorants (PC) for preparation of fish cake using molding device and response surface methodology (RSM). The results of the RSM program for processing of fish cake indicated that the amount optimization of independent variables based on the dependent variables (Y₁, gel strength; Y₂, overall acceptance) for high-quality FC were 263.8 g for SM, 88.5 g for TBS, 0.11 g for NTC and 0.20 g for PC. Hunter redness and overall acceptance of fish (salmon) cake, which was prepared under the optimum amounts, were 13.82 and 8.33 score, respectively. The fish (salmon) cake was superior in sensory overall acceptance to commercial fish cake.

• Radiation Oncology Journal
• /
• v.37 no.2
• /
• pp.127-133
• /
• 2019

Purpose: The aim of this study was to identify volume changes and dose variations of rectum and bladder during radiation therapy in prostate cancer (PC) patients. Materials and Methods: We analyzed 20 patients with PC treated with helical tomotherapy. Daily image guidance was performed. We re-contoured the entire bladder and rectum including its contents as well as the organ walls on megavoltage computed tomography once a week. Dose variations were analyzed by means of Dmedian, Dmean, Dmax, V₁₀ to V₇₅, as well as the organs at risk (OAR) volume. Further, we investigated the correlation between volume changes and changes in Dmean of OAR. Results: During treatment, the rectal volume ranged from 62% to 223% of its initial volume, the bladder volume from 22% to 375%. The average Dmean ranged from 87% to 118% for the rectum and 58% to 160% for the bladder. The Pearson correlation coefficients between volume changes and corresponding changes in Dmean were -0.82 for the bladder and 0.52 for the rectum. The comparison of the dose wall histogram (DWH) and the dose volume histogram (DVH) showed that the DVH underestimates the percentage of the rectal and bladder volume exposed to the high dose region. Conclusion: Relevant variations in the volume of OAR and corresponding dose variations can be observed. For the bladder, an increase in the volume generally leads to lower doses; for the rectum, the correlation is weaker. Having demonstrated remarkable differences in the dose distribution of the DWH and the DVH, the use of DWHs should be considered.