• Journal of the Society of Cosmetic Scientists of Korea
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• v.31 no.4 s.54
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• pp.305-310
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• 2005

To obtain effective and safe depigmenting agents, we investigated the effects of Scirpi rhizoma, a medicine among Chinese herbs, on melanogenesis. Dried S. rhizoma was refluxed with 70% aqueous ethanol and the extract was evaporated to dryness. To determine the effects as a whitening agent, various in vitro tests were performed such as free radical scavenging activity, melanin formation assay, tyrosinase activity and expression of tyrosinase, TRP-1 and TRP-2(western blot and RT-PCR) in B16 melanoma cells. S. rhizoma showed scavenging activities of free radicals and reactive oxygen species (ROS) with the $IC_{50}\;of\;638{\mu}g/mL$ against 1,1-diphenyl-2-picrylhydrazyl (DPPH) radical and $21.7{\mu}g/mL$ against superoxide radicals in the xanthine/xanthine oxidase system, respectively. S. rhizoma significantly inhibited melanin production in B16 melanoma cells. S. rhizoma treatment(48 h) suppressed the biosynthesis of melanin up to 27% at 100{\mu}g/mL$ and reduced tyrosinase activity up to 31% at $100{\mu}g/mL$ in B16 melanoma cells. S. rhizoma was also able to significantly inhibit tyrosinase and TRP-1 expression in protein and mRNA level. These results suggest that S. rhizoma inhibited melanin biosynthesis by regulating tyrosinase activity and expression in B16 melanoma cells. Therefore, S. rhizoma may be useful as a new antioxidant and whitening agent to inhibit melanogenesis.

• Journal of the Society of Cosmetic Scientists of Korea
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• v.31 no.4 s.54
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• pp.323-327
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• 2005

Although many studies have been performed to elucidate the molecular consequence of ultraviolet irradiation on an aging, little is known about the effect of natural products. Matrix metalloproteinases (MMPs) we known to play an important role in (a) photoaging. Hete we investigated the effect of $1,2,4,6-tetra-O-galloyl-{\beta}-{_D}-gluco- pyranose (1)$ and 3,4,5-trihydroxybenzoic acid (2) on the expression of MMP-1 in UVA-irradiated human skin fibroblasts (products), (on the) activity of MMP-1, and (on the) scavenging activities of free radicals. Compounds 1 and 2 were isolated from Melothria heterophylla (Cucurbitaceae). These compounds were found to scavenge free radicals and reactive oxygen species (ROS) and were measured to have the $SC_{50}$ values of $3.9{\mu}M\;and\;13.3{\mu}M$ against the 1,1-diphenyl-2-picrylhydrazyl (DPPH) radicals and $4.3{\mu}M\;and\; 4.0{\mu}M$ against superoxide radicals in the xanthine/xanthine oxidase system, respectively. Compounds 1 and 2 showed a dose-dependent inhibitory effect on the e):pression and activity of MMP-1 in the UVA-irradiated human skin fibroblasts. Therefore, we concluded that compounds 1 and 2 significantly inhibited MMP-1 expression at the protein level. Also, these compounds were determined to have a potent antioxidant activity. From these results, we suggest that these compounds nay be used as (a) new anti-aging agents for the photo-damaged skin.

• Journal of the Society of Cosmetic Scientists of Korea
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• v.31 no.4 s.54
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• pp.329-335
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• 2005

In order to investigate the effects of Saussurea involucrata on (relationship between) aging (and Saussurea involucrata), we examined the activities of antioxidation, in vitro MMP inhibition and UVA-induced MMP-1 expression in human dermal fibroblasts. S. involucrata showed scavenging activities radicals and reactive oxygen species (ROS) with the $IC_{50}$ values of $3.89{\mu}g/mL$ against 1,1-diphenyl-2-picrylhydrazyl (DPPH) radical and $67.29{\mu}g/mL$ against superoxide radicals in the xanthine/xanthine oxidase system, respectively. At the concentration of $1000{\mu}g/mL$, S. involucrata showed 93.27% inhibition on lipid peroxidation of linoleic acid. S. involucrata inhibited the activities of MMP-1 in a does-dependent manner and the $IC_{50}$ value calculated from semi-log plots was $97.18{\mu}g/mL$. Also, UVA induced MMP expression in human dermal fibroblasts was reduced 42.86% by treatment with S. involucrata, and MMP-1 mRNA expression was reduced in a dose-dependent manner. Therefore S. involucrata was able to significantly inhibit MMP expression in protein and mRNA level. All these results suggested that S. involucrata might act as an anti-aging agent by antioxidation and reducing UVA-induced MMP-1 production.

• Journal of the Society of Cosmetic Scientists of Korea
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• v.31 no.4 s.54
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• pp.343-347
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• 2005

As aging occurs, ow skin gets more wrinkles, becomes drier and loses its elasticity. Validating the evaluation of skin elasticity is especially important, because it is not as visible as other signs of aging such as wrinkles. Here, we identified the correlation between age and the Parameters given by Cutometer, and (we present) the parameters of that reflect the decreases in skin elasticity along with ages (Ur/Uf, Ua/Uf, Ur/Ue, Ua, $r=0.687{\sim}0.725$). Also we developed an evaluation method to quantify the difference of skin by viewing or touching. A five-grade standard of Moire topographic photo scale on face was prepared using sensory evaluation of 20 to 61 year - old women. Based on this photo standard, scoring was performed using (a) 5-grade system by three specialists to obtain the consensus score. Significant negative correlations between age and results of Cutometer $(r=-0.687{\sim}-0.725)$, Moire topography scores (r=-938) were found. Finally we have shown the significance of the correlation between the result of Cutometer and the score of Moire topography (r=0.711). Our studies using Moire topography on face have confirmed that instrumental measurements reflect the decrease in shin elasticity, which is perceived visually.

• Journal of Korea Trade
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• v.25 no.7
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• pp.92-107
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• 2021

Purpose - This paper analyzes the relationship between trade facilitation and agricultural products exports and estimates the effects of trade facilitation in importing countries on Chinese agricultural products exports, which is of great significance for promoting agricultural trade between China,Japan and Korea and the governments of the three countries to formulate targeted trade facilitation policies. Design/methodology - Based on Wilson (2003) theoretical framework, this paper sets up its own trade facilitation level measurement system by involving four primary indicators and fifteen secondary indicators to evaluate the trade facilitation levels of Japan and Korea from 2011 to 2018 respectively. The paper selected the data on China's agricultural exports at the HS4 level from 2011-2018 and used a fixed-effects model to estimate the effect of changes in trade facilitation levels in trading partner countries on China's agricultural trade. Findings - Our main findings can be summarized as follows: the level of trade facilitation in importing countries has a significantly positive effect on China's agricultural exports. The higher the level of trade facilitation in trading partner countries, the more Chinese agricultural exports trade, i.e. for every 1 percentage point increase in the level of trade facilitation, the volume of exports will increase by 2.299%.The sub-sample test shows that China's main agricultural products exported to Japan and Korea, such as aquatic products, vegetables, fruits and other perishable fresh products, are particularly significantly affected by the level of trade facilitation. Originality/value - First, from the innovation of the research perspective, which is different from the analysis of the existing paper on the overall trade facilitation of all traded commodities. This article is based on the close trade relations between China, Japan and Korea, and the particularity of agricultural products, from the perspective of China's agricultural exports to Japan and Korea, discuss the impact of importing countries-Japan and Korea's trade facilitation levels on China's agricultural exports;Secondly, in this paper, the hierarchical data of the HS4 quartile is used to avoid the information loss of the industry, and to analyse the impact of the importing country's trade facilitation level on the export of different types of agricultural products more scientifically.

• 한국사회정책
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• v.25 no.3
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• pp.279-303
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• 2018

Since the introduction of the Riester Pension Scheme, the controversy has continued in the policy studies and the political debates. This study evaluates the achievements and limitations of the German Riester pension scheme and tries to derive policy implications for South Korea. As a result of the analysis, the most worthwhile achievement of the Riester Pension is to strengthen the role of the private pension schemes. Unlike other private pension schemes, it included a large part of lower income households. It also opened a new perspective of utilizing private pension schemes to accomplish the goals of the family policy. Despite these attainments, it does not reach the promised coverage rate. It also was revealed that the higher income households have concluded more Riester Pension Contracts than the targeted lower-income households. Due to high administration fee and incomplete information problems, benefit levels are supposed to be much lower than expected. It concludes, above all, despite some achievements, the Riester Pension Scheme will not fill completely the gap of old age income security caused by the reduction of the public pension system. The German case provides fruitful lessons for Korea. The introduction of a subsidized personal pension scheme in South Korea can be realized only when some prerequisites would be satisfied such as the consolidation and maturing of public pension schemes and the strengthening of the transparency in the private pension market.

• Journal of the Korean Institute of Gas
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• v.23 no.4
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• pp.40-45
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• 2019

This paper is a purpose to study the failure example for heavy-duty vehicle fire. The first example, the researcher found the engine over-heating phenomenon causing a coolant leakage by the sealing poor of head-gasket because of D-ring part deformation contacting with cylinder liner top-part and cylinder head. He certified a fire breakout by short transferred to surrounding wiring of air-cleaner. The second example, a brake lining by return fault of break operating S cam causing with much wear of a rear 4 wheel brake lining repeatably was worn by friction. In the long run, it became the cause of fire. The third example, the researcher knew the fire cause was came about the short of wire by overload of tilting motor when the driver tilted up the cap to inspect a engine. Therefore, a heavy-duty fire must minimize the fire occurrence by thorough controlling.

• Journal of Korean Medicine Rehabilitation
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• v.29 no.3
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• pp.75-85
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• 2019

Objectives This study was perfomed to assess the adherance to CARE (CAse REport) guideline of case reports in the Journal of Korean Medicine Rehabilitation Methods We searched the case reports published in the Journal of Korean Medicine Rehabilitation from January 2016 to April 2019 in the database of oriental medicine advanced searching integrated system (OASIS). Then we evaluated the quality of the searched case reports based on the CARE guideline. Results Totally 31 papers were selected after the screening the case reports by the inclusion and exclusion criteria. The report rate of the sub-items of the CARE guideline was 78.26% at the maximum, 60.87% at the maximum, and 70.97% on the average. The following items were reported only in less than 50% of them; 'Timeline', 'Diagnostic challenges', 'Diagnostic reasoning including other diagnoses considered' 'Prognostic characteristics', 'Follow-up and Outcomes', 'Patient Perspective', 'Informed Consent' Conclusions This study is expected to contribute to the overall improvement of the level of case reports in the Journal of Korean Medicine Rehabilitation.

• Korean Journal of Family Social Work
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• no.57
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• pp.217-253
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• 2017

This study examines the process of developing and managing parent participation education programs, its performance, and its factor of deriving performance targeted on multi-cultural parents with children in early elementary school. Particularly, opinions of multi-cultural parents were considered and every process of developing and managing the program in this study was reflected. The analysed results were largely divided into three upper categories, which were 'growing as parents', 'forming new multi-culturalism', 'creating support system', and eight sub-categories. In addition, the factors that led to the positive achievement of program were appeared as 'development of active education program', 'organization and operation of parent inclusive program', 'utilization of flexible group structure', 'implementation of close interaction and communication between the members of the development team and the management team'. Based on the following results, we propose development and management process for effective multi-cultural parent education program.

• 한국노년학
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• v.32 no.4
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• pp.1199-1215
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• 2012

The purpose of this study is to investigate the determinants of job satisfaction among care givers. Finding out the determinants of job satisfaction among care givers, the dependent variables were defined 3 groups with 9 sub-factors, such as personal factors of growth needs and self-efficacy, job factors of job diversity, job autonomy, job importance, role clarity and workload, organizational factors of comradeship, education & training. For the study, data were collected form 479 care givers working in 52 care facilities of Chung Nam Province and analyzed them by regression analysis technique using the SPSS 20.0 statistical package. The results are as followings, job diversity, job importance, comradeship, education & training have positive effects on job satisfaction respectively, workload effects on it negatively, but growth needs, self-efficacy, job autonomy, role clarity no effectiveness on job satisfaction. Based on the results of study, theoretical implications are discussed for care givers to promote the job satisfaction and suggested the directions for further study. Further more, the findings provide the basic sources for care giver human resource management in long term care facilities which are suffering from recruiting of care giver, and it also contribute to successful management of long term care insurance system as a meaningful suggestion.