• 한국항만학회지
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• 제8권2호
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• pp.37-56
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• 1994

The effects of wave energy focusing by a submerged berm type of structure is examined. The fundamental idea is based on the phenomenon of refraction by a lens-shaped crescent structure which results in the focusing of wave energy on the center line of the structure. The shape of the submerged structure is a complex curve combining circular with elliptical elements. Based on the design procedure, a special configuration of structure(termed herein as a triple crescent structure) is introduced. Next, some hydraulic model tests are performed to confirm the wave focusing effect in laboratory. In addition, in order to interpret the wave focusing performance behind the structure, a numerical procedure by the hybrid element method is used on the basis of the conventional mild slope equation but modified and extended to allow for steeper bottom slopes and higher curvature. The modified refraction and diffraction provide additional mechanism for wave height amplification and the maximum amplification for triple crescent structure is presented. It also allows for the possibility of wave energy scattering with the change of the incident wave direction. Comparisons with previous theoretical results involving a submerged crescent shape structure are described.

• Applied Microscopy
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• 제51권
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• pp.13.1-13.7
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• 2021

The novel coronavirus, severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has arisen as a global pandemic affecting the respiratory system showing acute respiratory distress syndrome (ARDS). However, there is no targeted therapeutic agent yet and due to the growing cases of infections and the rising death tolls, discovery of the possible drug is the need of the hour. In general, the study for discovering therapeutic agent for SARS-CoV-2 is largely focused on large-scale screening with fragment-based drug discovery (FBDD). With the recent advancement in cryo-electron microscopy (Cryo-EM), it has become one of the widely used tools in structural biology. It is effective in investigating the structure of numerous proteins in high-resolution and also had an intense influence on drug discovery, determining the binding reaction and regulation of known drugs as well as leading the design and development of new drug candidates. Here, we review the application of cryo-EM in a structure-based drug design (SBDD) and in silico screening of the recently acquired FBDD in SARS-CoV-2. Such insights will help deliver better understanding in the procurement of the effective remedial solution for this pandemic.

• 한국소음진동공학회:학술대회논문집
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• 한국소음진동공학회 2004년도 춘계학술대회논문집
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• pp.237-242
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• 2004

In design stage of high precision manufacture/inspection FAB building, it is necessary to investigate the vibration allowable limits of high precision equipment and to study a structure dynamic characteristics of C/R and Sub-structure in order to provide a structure vibration environment to satisfy thess allowable limits. The aim of this study is to investigate the dynamic characteristics of PC-Type mock-up structures designed for next TFT LCD FAB through vibration measurement and analysis procedure, therefore, to provide a proper dynamic structure design for high precision manufacture/inspection work process, which satisfy thess allowable limits.

• 국제강구조저널
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• 제18권5호
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• pp.1598-1606
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• 2018

An integrated optimal structural design method for a diagrid structure and control device was developed. A multi-objective genetic algorithm was used and a 60-story diagrid building structure was developed as an example structure. Artificial wind and earthquake loads were generated to assess the wind-induced and seismic responses. A smart tuned mass damper (TMD) was used as a structural control system and an MR (magnetorheological) damper was employed to develop a smart TMD (STMD). The multi-objective genetic algorithm used five objectives including a reduction of the dynamic responses, additional stiffness and damping, mass of STMD, capacity of the MR damper for the integrated optimization of a diagrid structure and a STMD. From the proposed method, integrated optimal designs for the diagrid structure and STMD were obtained. The numerical simulation also showed that the STMD provided good control performance for reducing the wind-induced and seismic responses of a tall diagrid building structure.

• 한국전산유체공학회:학술대회논문집
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• 한국전산유체공학회 2011년 춘계학술대회논문집
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• pp.605-607
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• 2011

A Study on the flow-structure characteristics of a 3/2 way pneumatic valve is essential for optimizing the performance of ship engines. It is important for the valve to have desirable safety factor am reduced weight from the safety and economic point of view. In this study, we capture flow-structure characteristics of 3/2 way pneumatic valve. This is optimized based on the proper design criteria. The air at a pressure of 30 bar is the working fluid which is made to fill in the tack in short time. This time is defined as the filling time. The flow and structure analysis is performed for three cases under maximum stress and safety factor. In optimum design, considering the flow-structure characteristics, we model twenty seven cases by using DOE(design of experiments) method Here, analysis for each cases is performed and then metamodels are created We obtain optimized parameters and then analysis is repeated to compare with the initial model. Finally, the feasibility of the optimum design is verified.

• 전기전자학회논문지
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• 제19권4호
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• pp.590-595
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• 2015

본 논문은 타일 기반 레스터라이져에서 연산이 필요하지 않은 하위 계층에 대한 호출을 막아 연산의 효율을 올릴수 있는 계층 구조의 설계를 제안한다. 제안하는 계층 구조는 내외부 판정과 각 하위 계층이 가지는 타일의 최대 좌표값, 최소 좌표값을 이용하여 하위 계층을 3가지 형태로 분류한다. 각 하위 계층이 분류되는 형태에 따라 해당 계층의 연산의 필요 여부를 구분할 수 있으며 연산이 필요하지 않는 하위 계층에 대한 호출을 수행하지 않는 것으로 그래픽 처리과정의 전체 연산량을 줄일 수 있다. 제안하는 구조를 이용하여 하위 계층의 분류를 통해 그래픽 처리의 연산 시간을 줄일 수 있으며 3D 모델을 구성하는 정점의 밀집도가 클수록 높은 효율을 보인다.

• 한국가스학회지
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• 제9권4호
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• pp.36-43
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• 2005

본 논문은 다구찌 설계방법을 이용하여 LNG저장탱크의 지붕 구조물에 대한 최적설계 조건을 확보하기 위해 FEM해석을 수행하였다. 다구찌 설계방법은 저장탱크 구조물의 설계인자에 가장 큰 영향을 미치는 파라메터를 고찰하고 최적화하는데 유용한 결과를 제시하였다. 다구찌 설계방법으로 수행된 FEM 해석결과에 따르면, LNG저장탱크 지붕 구조물의 최적설계에 필요한 인자로 지붕 중심부의 두께를 언급하고 있다. 안전하면서 효율적인 지붕을 건설하기 위한 철근 콘크리트 지붕의 초기 구조물 설계는 반경방향의 H빔과 원주방향의 L빔을 가능한 작은 수량으로 배열하고 두꺼운 지붕 구조물을 갖춘 LNG 외부탱크가 최적이라는 해석결과를 제시한다.

• 한국구조물진단유지관리공학회 논문집
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• 제19권1호
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• pp.81-89
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• 2015

본 연구에서는 철근콘크리트구조에서 전단벽체를 대상으로 설계단계에서부터 Set-Based Design과 계층화분석기법을 통하여 선정된 최적배근그룹을 적용한 S-BIM기반 자동철근배근시스템 제안을 목적으로 한다. 복합적인 기준에 대한 쌍대비교 분석을 통해 최적 철근배근그룹을 선정하고 BIM 소프트웨어 벤더 (Vendor)에서 제공하는 Open API를 이용하여 구조설계 알고리즘을 통한 부재의 생성 및 철근배근이 자동으로 수행될 수 있도록 하였다. 결과적으로 가중치가 가장 높은 ALT1 (0.142)의 최적철근배근그룹이 선정되었고, 이를 TS상에 생성하였다.

• 한국전산유체공학회:학술대회논문집
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• 한국전산유체공학회 2005년도 춘계 학술대회논문집
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• pp.187-190
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• 2005

In this study, the reliablility based design optimization is peformed for an aircraft wing. The flexiblility of the wing was assumed by considering the interaction modeled by static aeroelasticity between aerodynamic forces and the structure. For a multidisciplinary design optimization the results of aerodynamic analysis and structural analysis were included in the optimization formulation. The First Order Reliability Method(FORM) was employed to consider the uncertainty of the designed points.

• 한국고분자학회:학술대회논문집
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• 한국고분자학회 2006년도 IUPAC International Symposium on Advanced Polymers for Emerging Technologies
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• pp.19-20
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• 2006

We report the design of electroluminescent conjugated polymers for high efficiency, turn-on voltage, color Tuning, and easy processing. Three approaches for the design are reported, being: (1) single chain consideration, (2) supramolecular structure consideration, and (3) conformation manipulation. Two polymer systems are to be reported, being fluorene-based and carbazole-based conjugated polymers.