• Food preservation and processing industry
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• v.6 no.2
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• pp.11-13
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• 2007

This study relates to low and medium molecular weight isoflavone-${\beta}$-D-glucan produced by submerged liquid culture of Agaricus blazei, a method of producing the isoflavone-B-D-glucan using autolysis enzyme of Agaricus blazei mycelia, and use of the isoflavone-B-D-glucan for anti-cancer and immunoenhancing effect. In acordance with one aspect of the present study, it deals with a method of producing isoflavone-${\beta}$-D-glucan, which comprises the followings; 1) culturing and separating mushroom mycelia, 2) producing low-medium molecular weight isoflavone-${\beta}$-D-glucan from high molecular weight one. The cytotoxicity on human cnacer cell line (Caco-2, MCF-7), the expression of Cyclin D, Bcl-2, Bax protein, p21 protein, p53 protein in MCF-7 cells assessed by SDS-PAGE and immunoblotting, and other immuno related factor such as TNF-a and IL-1B activities were examined. Structural identification of isoflavone-${\beta}$-D-glucan which shoed cytotoxicity against cancer cell and immunoenhancing effects was carried by separation with DEAE-cellulose column chromatography, TLC, HPLC, IR, NMR, Clinical test for the cancer patients (n=119) for 6 month was carried out, and immunoenhancing factors(NK cell number, ratio of T4/T8) were checked. We concluded the identified isoflavone-${\beta}$-D-glucan has immuno enhancing effects and could be useful for cancer chemoprevention.

• Structural Engineering and Mechanics
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• v.69 no.5
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• pp.567-577
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• 2019

Guyed steel lattice towers (or guyed masts) are widely used for supporting antennas for telecommunications and broadcasting. This paper presents a numerical study on the static and dynamic response of guyed towers. Three-dimensional nonlinear finite-element models are used to simulate the response. Through performing static pushover analyses and free-vibration (modal) analyses, the effect of different bracing configurations is investigated. In addition, seismic analyses are performed on towers of different heights to study the influence of earthquake excitation time-lag (or the earthquake travel distance between tower anchors) and antenna weight on the seismic response of guyed towers. The results show that the inclusion of time lag in the seismic analysis of guyed towers can influence shear and moment distribution along the height of the mast. Moreover, it is found that the lateral response is insensitive to bracing configurations. The results also show that, depending on the mast height, an increased antenna weight can reduce the tower maximum base shear while other response quantities, such as cables tension force are found to be insensitive to variation in the antenna weight.

• Steel and Composite Structures
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• v.38 no.5
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• pp.599-615
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• 2021

The ultimate strength behaviour of sandwich composite beams with J-hooks and normal weight concrete (SCSSBJNs) are studied through two-point loading tests on ten full-scale SCSSBJNs. The test results show that the SCSSBJN with different parameters under two-point loads exhibits three types of failure modes, i.e., flexure, shear, and combined shear and flexure mode. SCSSBJN failed in different failure modes exhibits different load-deflection behaviours, and the main difference of these three types of behaviours exist in their last working stages. The influences of thickness of steel faceplate, shear span ratio, concrete core strength, and spacing of J-hooks on structural behaviours of SCSSBJN are discussed and analysed. These test results show that the failure mode of SCSSBJN was sensitive to the thickness of steel faceplate, shear span ratio, and concrete core strength. Theoretical models are developed to estimate the cracking, yielding, and ultimate bending resistance of SCSSBJN as well as its transverse cross-sectional shear resistance. The validations of predictions by these theoretical models proved that they are capable of estimating strengths of novel SCSSBJNs.

• Computers and Concrete
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• v.29 no.6
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• pp.361-374
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• 2022

On the premise of ensuring that the automatic and quantitative discharging function of concrete conveyors is met, the accuracy of the weight forecast by the mathematical model of the screw conveying volume is improved, and the error of the weight of the concrete parts and the accumulation thickness is reduced. In this paper, the discrete element method (DEM) is used to simulate the macroscopic flow of concrete. Using the concrete discrete element model, the size of the screw conveyor is set, and establish the response model between the influencing factors (process and structure) and the concrete mass flow rate according to the design points of the screw discharging experiment. The nonlinear data fitting method is used to obtain the volumetric efficiency function under the influence of process and structural factors, and the traditional screw conveying volume model is improved. The mass flow rate of concrete predicted by the improved mathematical model of screw conveying volume is consistent with the test results. The model can accurately describe the conveying process of concrete and achieve the purpose of improving the accuracy of forecasting the weight of discharged concrete.

• Wind and Structures
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• v.34 no.3
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• pp.291-301
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• 2022

Although mostly used in wind turbine market, single rotor wind turbines have problems with transportation and installation costs due to their large size. In order to solve such problems, multi-rotor wind turbine is being proposed; however, light weight design of multi-rotor wind turbine is required considering the installation at offshore or deep sea. This study proposes the systematic design process of the multi-rotor wind turbine focused on its supporting structure with simultaneous consideration of static and dynamic behaviors in an ideal situation. 2D and successive 3D topology optimization process based on the density method were applied to minimize the compliance of supporting structure. To realize the conceptual design obtained by topology optimization for manufacturing feasibility, the derived 3D structure was modified to have shell structures and optimized again through parametric design using the design of experiments and the response surface method for detail design of their thicknesses and radii. The resultant structure was determined to satisfy the stress and the buckling load constraint as well as to minimize the weight and the resultant supporting structure were verified numerically.

• Journal of the Korean GEO-environmental Society
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• v.24 no.12
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• pp.19-29
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• 2023

The main problem with roads is that cracks and settlement occur over time due to loads acting from the surface layer. One way to solve this problem is to use Geocell. Geocell can be used for structural reinforcement for erosion prevention, ground stabilization on flat and steep slopes, load bearing, and ground preservation. In this study, analyzed road pavement application cases using Geocell and purpose of this study is to analyze the bearing capacity of a road paving method including Geocell using field tests and LFWD(Light Falling Weight Deflectometer) equipment. In addition, the bearing capacity was compared and analyzed with the existing traditional road pavement method.

• Journal of the Ergonomics Society of Korea
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• v.31 no.2
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• pp.327-336
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• 2012

Objective: The purpose of this study is to find the problems of stability when people use the bassinet as an ambulatory aid for old people. Background: Many aged people use a bassinet as ambulatory aid. But the safety of using the bassinet as ambulatory aid has not been verified yet. Method: The 13 university-students who don't have musculoskeletal disorders volunteered to participate in this study. According to structural analysis of the both tools, we compared the structural stability of an outdoor rollator with the structural stability of a bassinet. And when the participants walked using both tools, the motions were captured and analysed. We measured the angle of shoulder joint and the angle of trunk from the ground when the participants were walking. And we found the distance from participants' pressure cone apex and greater trochanter. Results: Following the structural analysis, the bassinet has the lower structural stability than the outdoor rollator. When the people used the bassinet as ambulatory aid, the angle of the shoulder joint was bigger than to use the outdoor rollator. The angle of trunk wasn't different between the outdoor rollator and the bassinet. And distance from pressure cone apex to greater trochanter was far to use the bassinet than to use the outdoor rollator. Conclusion: Through the structure analysis and gait analysis of the bassinet and the outdoor rollator, we can be aware of that the bassinet has problem of stability. Therefore the people who use the bassinet as an ambulatory aid, especially supporting body weight, may be hurt due to the problems of stability. Application: This research can be used for developing a study of the ambulatory aid and preventing the accident when the aged people use the ambulatory aid.

• Journal of the Computational Structural Engineering Institute of Korea
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• v.33 no.3
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• pp.187-192
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• 2020

To reduce fuel consumption by reducing the weight of the deck of a dump truck and to design an eco-friendly deck, accurate structural analysis is required. To date, the load on the deck has been calculated based on the hydrostatic pressure or by applying the earth pressure theory. However, these methods cannot be used to determine the non-uniformity of the load on the deck. Load distribution varies depending on the size distribution and interaction of aggregate particles. Compared with the finite element method, the discrete element method can simulate the behavior of aggregate particles more effectively. In this study, major properties were obtained by measuring bulk density and repose. The deck of a 15 ton dump truck was simulated using the obtained properties and bumping, breaking, and turning load conditions were applied. EDEM, which is a discrete element analysis software, was employed. The stress and strain distribution of the deck were calculated by NASTRAN and compared with the measured values. The study revealed that the results derived from a DEM simulation were more accurate than those based on mathematical assumption.

• Journal of Soil and Groundwater Environment
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• v.20 no.7
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• pp.70-79
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• 2015

A sample of soil humic acid (HA) was divided by ultrafiltration (UF) into five fractions of different molecular size (UF₁: > 300, UF₂: 100~300, UF₃: 30~100, UF₄: 10~30, UF₅: 1~10 kilodaltons). Apparent average molecular weight (M_w) of the HA fractions were measured using high performance size exclusion chromatography (HPSEC), and the chemical and structural properties of the five HA fractions were characterized by elemental compositions (H/C, O/C and w ((2O + 3NH)/ C)) and ultraviolet-visible absorption ratios (SUVA, A_4/6). The organic carbon normalized-sorption coefficients (Koc) for the binding of phenanthrene to the HA fractions were determined by fluorescence quenching and relationship between the sorption coefficients and structural characteristics of the HA fractions were investigated. The elemental analysis and UV-vis spectral data indicated that the HA fractions with higher molecular weights have grater aliphatic character and lower contents of oxygen, while the HA fractions with lower molecular size have greater aromatic character and molecular polarity that correspond to greater SUVA and internal oxidation values (w). The log Koc values (L/kg C) were gradual increased from 4.45 for UF₅ to 4.87 for UF1. The correlation study between the structural descriptors of the HA fractions and log Koc values of phenanthrene show that the magnitude of Koc values positively correlated with $M_w$ and H/C, while negatively correlated with the independent descriptors of the O/C, w, SUVA and A_4/6.

• Composites Research
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• v.13 no.2
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• pp.61-71
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• 2000

Today, the use of composite materials become an essential part in the design and manufacturing process of the flight vehicles to reduce the structural weight. Since the structural properties can be varied largely due to the stacking sequence of ply angles, it is very important problem to determine the optimized ply angles under a design objective. Thus, in this study, the analysis of static aeroelastic optimization of a composite wing has been performed. An analytical system to calculate and optimize tile aero-structural equilibrium position has been developed and incorporated with the genetic algorithm. The effects of stacking sequence on the structural deformation and aerodynamic distribution have been studied and calculated with the condition of minimum structural deformation for a swept-back composite wing. For the set of practical stacking angles, the design results to maximize the performance of static aeroelasticity are also presented.