• Journal of the Korean Society of Manufacturing Technology Engineers
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• v.21 no.6
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• pp.897-902
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• 2012

Low speed vehicle(LSV), golf carts have unique requirements to differential gear design. For double axle torque LSV differential loading conditions were determined with the help of analytical model and ANSYS finite element analysis. With stress safety factor 3.15, fatigue safety factor 1.08 and fatigue life 106 cycle ring gear teeth strength analysis is performed and structure design optimized. This allows reducing overall cost of differential unit.

• Journal of the Optical Society of Korea
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• v.19 no.6
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• pp.643-648
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• 2015

By comparing the results calculated by atan() and atan2() functions, the correctly estimated region of isoclinic phase map is determined using morphological techniques. The isoclinic phase map is automatically unwrapped in the true phase range -π/2 to π/2. Demonstrations of the method on a disc and a ring under diametral compression are performed. Test results compare well with the theoretical results. Furthermore, the influences of principal stress direction and the range of isoclinic phase upon stress separation are discussed.

• Transactions of the Korean Society of Mechanical Engineers A
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• v.27 no.9
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• pp.1597-1606
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• 2003

Static analysis using hybrid finite element(FE) method has been applied to characterize the influence of position, runout and thickness errors of the sun, ring and planet on the bearing forces and critical tooth stress. Some guidelines for tolerance control to manage critical stress and bearing forces are deduced from the results. Carrier indexing error planet assembly and planet tooth thickness error are most critical to reduce planet bearing force and maximize load sharing as well as to reduce critical stresses. Sun and carrier bearing forces due to errors increase several times more than those of normal condition.

• Proceedings of the KIEE Conference
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• 1999.07g
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• pp.3301-3303
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• 1999

A new method of measuring residual stresses in micromachined films using beam or ring structures is proposed. Using the proposed method, more exact value of residual stress can be obtained without any ambiguities in conventional buckling method. Theoretical modeling with respect to this method is described, and experiment is performed. The structure and fabrication process in this paper are simple and widely used in surface micromachining. Therefore, it is possible to obtain a synchronous measurement. A synchronous and reason -able estimation of residual stresses in micromachined films enables us to obtain the prediction of more exact performance in micromachined devices.

• Biomolecules & Therapeutics
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• v.29 no.2
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• pp.195-204
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• 2021

Cereblon (CRBN), a substrate receptor of cullin 4-RING E3 ligase (CRL4) regulates the ubiquitination and degradation of c-Jun, mediating the lipopolysaccharide-induced cellular response. However, the upstream signaling pathway that regulates this process is unknown. In this study, we describe how endoplasmic reticulum (ER) stress reversely regulates sequestosome-1 (p62)and c-Jun protein levels. Furthermore, our study reveals that expression of p62 attenuates c-Jun protein levels through the ubiquitinproteasome system. Conversely, siRNA knockdown of p62 elevates c-Jun protein levels. Immunoprecipitation and immunoblotting experiments demonstrate that p62 interacts with c-Jun and CRBN to form a ternary protein complex. Moreover, we find that CRBN knockdown completely abolishes the inhibitory effect of p62 on c-Jun. Using brefeldin A as an inducer of ER stress, we demonstrate that the p62/c-Jun axis participates in the regulation of ER stress-induced apoptosis, and that CRBN is required for this regulation. In summary, we have identified an upstream signaling pathway, which regulates p62-mediated c-Jun degradation. Our findings elucidate the underlying molecular mechanism by which p62/c-Jun axis regulates the ER stress-induced apoptosis, and provide a new molecular connection between ER stress and apoptosis.

• Journal of the Korean Society for Precision Engineering
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• v.14 no.8
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• pp.29-39
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• 1997

The clamp, as the structure which is used for supporting the pipe in the atomic power plant, is produced with a certain degree of anticlastic curvature in the current manufacturing process. In this study, the structural analysis of the clamp and the pipe was performed using ABAQUS. And the finite element modelling for the analysis was made by an HyperMesh. The contact forces which are transferred between the clamp and the pipe for the external force are changed according to the binding force of bolts and keeps the clamp tightly and protects the slipping between the clamp and the pipe. The clamps with the anticlastic curvature and with the flat curvature are considered in order to invest the anticlastic effect. In this study, another case is suggested. The present case does not have the stiffness ring on the end of the clamp but the suggested case has the ring. For the present case, the results showed that the equivalent stress is higher in the anticlastic curvature case than in the flat curvature case and the equivalent stresses on the pipe are almost the same as the binding force increses. For the suggested case, the result showed that the equivalent stress in the anticlastic curvature case decreases until some binding force and increases as the binding forces increase and is lower in some range than in the flat curvature case. From this study, the clamp with the anticlastic curvature in the suggested method is better than the clamp with the flat curvature and the optimal binding force are given.

• Korean Journal of Materials Research
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• v.8 no.3
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• pp.200-205
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• 1998

The nature, degree, and evolution of contact damage from Hertzian contacts in silicon nitride-boron nitride composites($Si_3N_4-BN$) are investigated as a function of boron nitride content. The strong deviations of indentation stress-strain from elastic response indicate exceptional plasticity in $Si_3N_4-BN$. The absence of ring cracks or cone cracks on the surfaces is observed, indicating a high damage tolerance. Subsurface quasi- plastic deformation by shear stress is considerable and microdamage is widely distributed within the region below the contact. Shear faults associated with local microfailures play a precursor role in plasticity of this material. When boron nitride content increases, $Si_3N_4-BN$ becomes softer and more quasi-plastic.

• Structural Engineering and Mechanics
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• v.66 no.3
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• pp.343-351
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• 2018

Brazilian disc test is one of the most widely used experiments in the literature of geo-mechanics. In this work, the pre-holed concrete Brazilian disc specimens are numerically modelled by a two-dimensional discrete element approach. The cracks initiations, propagations and coalescences in the numerically simulated Brazilian discs (each containing a single cylindrical hole and or multiple holes) are studied. The pre-holed Brazilian discs are numerically tested under Brazilian test conditions. The single-holed Brazilian discs with different ratios of the diameter of the holes to that of the disc radius are modelled first. The breakage load in the ring type disc specimens containing an internal hole with varying diameters is measured and the crack propagation mechanism around the wall of the ring is investigated. The crack propagation and coalescence mechanisms are also studied for the case of multi-holes' concrete Brazilian discs. The numerical and experimental results show that the breaking mechanism of the pre-holed disc specimens is mainly due to the initiation of the radially induced tensile cracks which are growth from the surface of the central hole. Radially cracks propagated toward the direction of diametrical loading. It has been observed that for the case of disc specimens with multiple holes under diametrical compressive loading, the breaking process of the modelled specimens may occur due to the simultaneous cracks propagation and cracks coalescence phenomena. These results also show that as the hole diameter and the number of the holes increases both the failure stress and the crack initiation stress decreases. The experimental results already exist in the literature are quit agree with the proposed numerical simulation results which validates this simulation procedure.

• Advances in concrete construction
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• v.14 no.2
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• pp.93-102
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• 2022

In this study, limestone powder (LS) and fly ash (FA) were used as powder materials in self-compacting concrete (SCC) in increasing quantities in addition to cement, so that the two powders commonly used in the production of SCC could be compared in the same study. Considering the reduction of the maximum aggregate size in SCC, 10 mm or 16 mm was selected as the coarse aggregate size. The properties of fresh concrete were determined by slump flow (including T₅₀₀ time), V-funnel and J-ring experiments. The experimental results showed that as the amount of both LS and FA increased, the slump flow also increased. The increase in powder material had a negative effect on V-funnel flow times, causing it to increase; however, the increase in FA concretes was smaller compared to LS ones. The increase in the powder content reduced the amount of blockage in the J-ring test for both aggregate sizes. As the hardened concrete properties, the compressive and splitting strengths as well as the modulus of elasticity were determined. Longitudinal and transverse deformations were measured by attaching a special frame to the cylindrical specimens and the values of Poisson's ratio, initiation and critical stresses were obtained. Despite having a similar W/C ratio, all SCC exhibited higher compressive strength than NVC. Compressive strength increased with increasing powder content for both LS and FA; however, the increase of the FA was higher than the LS due to the pozzolanic effect. SCC with a coarse aggregate size of 16 mm showed higher strength than 10 mm for both powders. Similarly, the modulus of elasticity increased with the amount of powder material. Inelastic properties, which are rarely found in the literature for SCC, were determined by measuring the initial and critical stresses. Crack formation in SCC begins under lower stresses (corresponding to lower initial stresses) than in normal concretes, while critical stresses indicate a more brittle behavior by taking higher values.

• Proceedings of the Korea Society of Environmental Biology Conference
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• 2003.11a
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• pp.86-91
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• 2003

In this study, in order to examine whether salt and heat shock stress would alter or not contraction and relaxation of isolated rat aorta. Under anesthesia with sodium pentobarbital(50 mg Kg$^{-1}$ i.p.), male Sprague Dawley rats weighing 300-330 g were subjected to 0, heat shock combined salt stress, where as the sham group was left at modified Krebs-bicarbonate solution. To measure contractile response of vascular ring preparation isolated from rat was determined in organ bath and was recorded on physiograph connected to isometric transducer. And the strip was checked for expression of heat shock protein(Hsps) by means of western blotting. The combination group of heat and 50 mM NaCl group increased vascular contractility, and the heat and 150 mM NaCl group decreased vascular contractility for 5 hours, and then recovered for 8 hours compared to that of control. Expressin of Hsp 70 of vascular muscle of rat aorta more increased by combination of heat and NaCl treatment than those of single treatment of heat or NaCl treatment, and vascular Hsp 70 showed a little decrease at 8 hours compared at 5 hours. These result indicate that mixed environmental stress either increased or decreased in vascular contractility by combination of heat and NaCl concentration.