• Title/Summary/Keyword: Stress intensities

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Heat stress during summer increases Caspase-3 activation in the ovary of domestic sow

  • Tae-Gyun Kim;Sung-Ho Kim;Sang-Yup Lee;Yong-Ho Choe;Junho Lee;Min Jang;Sung-Ho Yun;Young-Bum Son;Sung-Lim Lee;Seung-Joon Kim;Won-Jae Lee
    • Korean Journal of Veterinary Service
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    • v.47 no.3
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    • pp.123-132
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    • 2024
  • The stressful conditions including heat stress negatively affect to the animal's reproductive performance. Apoptosis of granulosa cells under unexpected stimuli can influence the fate of ovarian follicles and its function. Since the changes in caspase-3, a key executioner of the apoptosis pathway, have not yet been elucidated in heat-stressed sows, this study compared its changes in the ovaries of domestic sows affected by heat stress during summer. The samples were collected at spring (23.1℃; CON group) as suitable temperature for raising pigs or at summer (34.4℃; HS group) as unavoidable chronic heat stress. It was not significant but strong tendency to release higher level of stress hormone (corticosterone) in HS group than that in CON group was identified. A significant upregulation of cleaved (activated) caspase-3 expression in HS group was identified compared to CON group, indicating that apoptosis was increased in the ovarian follicles during summer. The expression of cleaved caspase-3 in the ovaries was positively related with degree of maximal atmospheric temperature and serum levels of corticosterone. The caspase-3-positive cells were more prevalent in mature follicles with localization primarily in the granulosa cell layer than immature follicles. The intensities of caspase-3 in the granulosa cell layer were stronger in HS group than CON group. In conclusion, the present study demonstrated that chronic heat stress during summer in Korea increased activated caspase-3-related apoptosis in the granulosa cells in the mature ovarian follicles, which might suggest that heat stress decreased reproductive performance in the domestic sows during summer.

Mechanisms of the Autonomic Nervous System to Stress Produced by Mental Task in a Noisy Environment (소음상황에서 인지적 과제에 의해 유발된 스트레스에 대한 자율신경반응의 기제)

  • Sohn, Jin-Hun;Estate M. Sokhadze;Lee, Kyung-Hwa;Kim, Yeon-Kyu;Park, Sangsup
    • Proceedings of the Korean Society for Emotion and Sensibility Conference
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    • 1999.11a
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    • pp.216-221
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    • 1999
  • A mental task combined with noise background is an effective model of laboratory stress for study of psychophysiology of the autonomic nervous system (ANS). The intensity of the background noise significantly affects both a subjective evaluation of experienced stress level during test and the physiological responses associated with mental load in noisy environments. Providing tests of similar difficulties we manipulated the background noise intensity as a main factor influencing a psychophysiological outcome and the analyzed reactivity along withe the noise intensity dimension. The goal of this study was to identify the patterns of ANS responses and the relevant subjective stress scores during performance of word recognition tasks on the background of white noise (WN) of the different intensities (55, 70 and 85 dB). Subjects were 27 college students (19-24 years old). BIOPAC, Grass Neurodata System and AcqKnowlwdge 3.5 software were used to record ECG, PPG, SCL, skin temperature, and respiration. Experimental manipulations were effective in producing subjective and physiological responses usually associated with stress. The results suggested that the following potential autonomic mechanisms might be involved in the mediation of the observed physiological responses: A sympathetic activation with parasympathetic withdrawal during mild 55 and 70dB noise (featured by similar profiles) and simultaneous activation of sympathetic and parasympathetic systems during intense 85dB WN. The parasympathetic activation in this case might be a compensatory effect directed to prevent sympathetic domination and to maintain optimal arousal state for the successful performance on mental stress task. It should be mentioned that obtained results partially support Gellhorn's (1960; 1970) "tuning phenomenon" as a possible mechanism underlying stress response.

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A Study on the Side Drop Impact of a Nuclear Spent Fuel Shipping Cask (사용후 핵연료 수송용기의 수평낙하충격에 관한 연구)

  • Chung, Sung-Hwan;Lee, Young-Shin
    • Transactions of the Korean Society of Mechanical Engineers A
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    • v.21 no.3
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    • pp.457-469
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    • 1997
  • A nuclear spent fuel shipping cask is required by IAEA and domestic regulations to withstand a 9m free drop condition. In this paper, the structural analysis under the 9m side drop condition was performed to understand the dynamic impact behavior and to evaluate the safety of the cask for 7 PWR nuclear spent fuel assemblies. The analysis result was compared with the measured value of the 9m side drop test for the 1/3 scaled-down model and the accuracy of the 3D analysis was confirmed. Analysis in accordance with the diameter of impact limiters for the proto-type cask were performed. Through the analysis, the impact behaviors due to the side drop and the effects dependent on the diameter of impact limiters were grasped. Maximum stress intensities on each part of the cask were respectively calculated by using the stress evaluation program and the structural safety of the cask was finally evaluated in accordance with the regulations.

Prediction of Wall Shear Stresses in Transitional Boundary Layers Using Near-Wall Mean Velocity Profiles

  • Jeon, Woo-Pyung;Shin, Sung-Ho;Kang, Shin-Hyoung
    • Journal of Mechanical Science and Technology
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    • v.14 no.11
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    • pp.1305-1318
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    • 2000
  • The local wall shear stress in transitional boundary layer was estimated from the near-wall mean velocity data using the principle of Computational Preston Tube Method(CPM). The previous DNS and experimental databases of transitional boundary layers were used to demonstrate the accuracy of the method and to provide the applicable range of wall unit y(sup)+. The skin friction coefficients predicted by the CPM agreed well with those from previous studies. To reexamine the applicability of CPM, near-wall hot-wire measurement were conducted in developing transitional boundary layers on a flat plate with different freestream turbulence intensities. The intermittency profiles across the transitional boundary layers were reasonably obtained from the conditional sampling technique. An empirical correlation between the representative intermittency near the wall and free parameter K$_1$of the extended wall function of CPM has been newly proposed using the present and other experimental data. The CPM has been verified as a useful tool to measure the wall shear stress in transitional boundary layer with reasonable accuracy.

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Design and Structural Safety Evaluation of Canister for Dry Storage System of PWR Spent Nuclear Fuels

  • Taehyung Na;Youngoh Lee;Taehyeon Kim;Donghee Lee
    • Journal of Nuclear Fuel Cycle and Waste Technology(JNFCWT)
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    • v.21 no.4
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    • pp.559-570
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    • 2023
  • The aim of this study is to ensure the structural integrity of a canister to be used in a dry storage system currently being developed in Korea. Based on burnup and cooling periods, the canister is designed with 24 bundles of spent nuclear fuel stored inside it. It is a cylindrical structure with a height of 4,890 mm, an internal diameter of 1,708 mm, and an inner length of 4,590 mm. The canister lid is fixed with multiple seals and welds to maintain its confinement boundary to prevent the leakage of radioactive waste. The canister is evaluated under different loads that may be generated under normal, off-normal, and accident conditions, and combinations of these loads are compared against the allowable stress thresholds to assess its structural integrity in accordance with NUREG-2215. The evaluation result shows that the stress intensities applied on the canister under normal, off-normal, and accident conditions are below the allowable stress thresholds, thus confirming its structural integrity.

Difference between Stress, Depression, and Self-esteem along with Physical Activity Levels in Overweight and Obese Perimenopausal Women (갱년기 과체중과 비만여성의 신체활동량에 따른 스트레스, 우울, 자존감의 차이 연구)

  • Hwang, Mi-Ja;Song, Mi-Yeon
    • The Journal of Churna Manual Medicine for Spine and Nerves
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    • v.2 no.2
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    • pp.105-116
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    • 2007
  • Objectives : Physical activity is known as beneficial to mental health like decreasing depression and stress. In this study, we tried to find out the relationship between body composition, stress, depression, and self-esteem with physical activity level. Methods : International Physical Activity Questionnaire(IPAQ)-short form, SRRS(Social readjustment rating scale), SRI(Stress response index), and BDI(Beck's depression index), SES(Self-esteem scale) were given to peri-menopausal women aged 45-55 and BMI$\geq$23kg/m2. They were given written consent and this study is performed under the permission of institutional review board of Kyung Hee East-west Neo Medical Center. Results : The mean of physical activity of total subjects was 2406MET-min/week(n=42). The physical activity of overweight(23kg/m2$\leq$BMI<25kg/m2) and obese(BMI$\geq$25kg/m2) permimenopausal women was 1428MET-min/week and 2970MET-min/week(p<0.05) respectively. When three levels of physical activity pattern(inactive, minimally active, and HEPA(Health-enhancing physical activity) active) was analyzed, all of them were heavily relied on the activity intensities of walking. The scores of BDI, SRRS, and SRI were lower and that of SES were higher in HEPA active group, not showing statical significance. Anger(subscale of SRI) measures were lower and SES measures were higher in HEPA active group than others among overweight women(p<0.05). Conclusions : The level of physical activity of peri-menopausal women was on the average, but the vigorous activity is thought to be necessary. The HEPA active group showed lower depression, stress and higher self-esteem than minimally active and inactive group.

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A Study on Gamma ray effects on Stress Response and Cellular Toxicity using Bacterial Cells

  • Min, Ji-Ho;Lee, Hyeon-Ju;Lee, Chang-U;Gu, Man-Bok
    • 한국생물공학회:학술대회논문집
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    • 2000.11a
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    • pp.187-190
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    • 2000
  • Effects of gamma ionizing radiation on recombinant Escherichia coli cells containing stress promoters, recA, fabA, grpE, or katG, fused to luxCDABE originated from Vibrio fischeri were characterized by monitoring transcriptional responses reflected by bioluminescent output. Quantification of gamma-ray intensity may be possible using the recA and fabA promoter fusion since a linear enhancement of bioluminescence emission with increasing gamma-ray intensity was observed. Other strains sensitive to either oxidative stress (DPD2511, katG::luxCDABE) or protein-damaging stress (TV1061, grpE::luxCDABE) were also irradiated by gamma-rays, and resulted in no noticeable bioluminescent output while DPD2794 with recA promoter and DPD2540 with fabA promoter irradiated by the same intensities of gamma-rays gave a significant bioluminescent output. This indicates that the main stresses in the recombinant bacteria caused by ionizing radiation are DNA and membrane-damage, not protein- or oxidative-damage. In addition, in this study, to investigate the relationship between the radiation dose rate and bacterial responses, two recombinant Escherichia coli strains, DPD2794 and GC2, containing lac promoter fused to luxCDABE originating from Photorhapdus luminescences, were used for detecting DNA damage and cellular toxicity under various radiation dose rates. Throughout this study, it was found that these bacteria showed quantitative stress responses to DNA damage and general toxicity caused by gamma rays, depending on the radiation dose rates, indicating that the bacterial stress responses and general toxicity were seriously influenced according to radiation dose rates.

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Effects of Ni Concentration on Residual Stress in Electrodeposited Ni Thin Film for 63Ni Sealed Source (63Ni 밀봉선원용 Ni 전기도금 박막에서 Ni 농도가 잔류응력에 미치는 영향)

  • Yoon, Pilgeun;Park, Deok-Yong
    • Journal of Surface Science and Engineering
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    • v.50 no.1
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    • pp.29-34
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    • 2017
  • Chloride plating solution was fabricated by dissolving metal Ni powders in a mixed solution with HCl and de-ionized water. Effects of $Ni^{2+}$ and saccharin concentrations in the plating baths on current efficiency, residual stress, surface morphology and microstructure of Ni films were studied. In the case of $0.2M\;Ni^{2+}$ concentration, current efficiency was decreased to about 65 % with increasing saccharin concentration, but, in the case of $0.7M\;Ni^{2+}$ concentration, it was shown more than 90 % with the increase of saccharin concentration. Residual stress of Ni thin film was appeared to be about 400 MPa up to 0.0244 M saccharin concentration at the $0.2M\;Ni^{2+}$ concentration and surface morphology with severe cracks was observed in the range of 0.0487~0.0975 M saccharin concentration. Residual stress of Ni thin films was measured to be about 750 MPa without saccharin addition and 114~148 MPa at the range of 0.0097~0.0975 M saccharin concentration for the $0.7M\;Ni^{2+}$ concentration. Relatively low residual stress values (114~148 MPa) of the Ni films at the range of 0.0097~0.0975 M saccharin concentration may be resulted from codeposition of S from saccharin. Ni films at $0.7M\;Ni^{2+}$ concentration showed smooth surface morphology and were independent of saccharin concentration. Ni films at $0.7M\;Ni^{2+}$ concentration consist of FCC(111), FCC(200), FCC(220) and FCC(311) peaks and the intensities of FCC(111) and FCC(200) peaks increased with increasing saccharin concentration. Also, the average grain size decreased with increasing saccharin concentration from about 30 nm to about 15 nm.

The Fracture Study of SCC of Al - Alloy for Marine Structures (해양구조물용 알미늄 합금의 SCC에 의한 파괴연구)

  • 김귀식
    • Journal of the Korean Society of Fisheries and Ocean Technology
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    • v.19 no.1
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    • pp.79-84
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    • 1983
  • The test specimen, designated the double cantilever beam, was employed for a fracture mechanics study of stress corrosion cracking (SCC) of type 5083 Al-alloy in seawater. Stress intensities for this DCB specimen were calculated by using compliance, strain energy release rate and relation between stress intensity and strain energy release rate. Analytical expression for compliance as a function of crack length was obtained by applying beam theory. It was investigated that the polarization potentials affected the growth rate and surface of stress corrosion cracking. The results are as follows, The critical stress intensity was 134.81-148.38kg/mm super(3/2) and K sub(Ii) under polarization potentials was 75.92-145.78kg/mm super(3/2). The minimum stress corrosion crack growth rate was occurred at-987mV SCE. Insoluble compound on $\beta$ phase was looked into through SCC. The greater anodic potential is, the larger insoluble compound on $\beta$ phase becomes.

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Analysis of Simple Creep Stress Calculation Methods for Creep Life Assessment (크리프 수명 평가를 위한 간략 크리프 응력 산출 방법론 분석)

  • Seo, Jun Min;Lee, Han Sang;Kim, Yun Jae
    • Transactions of the Korean Society of Mechanical Engineers A
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    • v.41 no.8
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    • pp.703-709
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    • 2017
  • Creep analysis takes much more time than elastic or elastic-plastic analysis. In this study, we conducted elastic and elastic-plastic analysis and compared the results with creep analysis results. In the elastic analysis, we used primary stress, which can be classified by the $M{\alpha}-tangent$ method and stress intensities recommended in the ASME code. In the elastic-plastic analysis, we calculated the parameters recommended in the R5 code. For the FE models, a bending load, uniaxial load, and biaxial load were applied to the cross shaped welded plate, and a bending load and internal pressure were applied to the elbow pipe. To investigate the element size sensitivity, we conducted FE analysis for various element sizes for the cases where bending load was applied to the cross shaped welded plate. There was no significant difference between the creep stress and the alternative methods; however, in the $M{\alpha}-tangent$ method, the results were affected by the element size.